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E-grāmata: 3D Printing Applications in Cardiovascular Medicine

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Edited by (Professor of Medicine and Professor of Radiology, Weill Cornell Medical College, Cornell University; Attending Radiologist, New York-Presbyterian Hospital, New York, NY, USA), Edited by , Edited by , Edited by (Assistant Professor of Biomedical Engineering in Radiology,)
  • Formāts: EPUB+DRM
  • Izdošanas datums: 04-Jul-2018
  • Izdevniecība: Academic Press Inc
  • Valoda: eng
  • ISBN-13: 9780128039434
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3D Printing Applications in Cardiovascular MedicinePalielināt
  • Formāts: EPUB+DRM
  • Izdošanas datums: 04-Jul-2018
  • Izdevniecība: Academic Press Inc
  • Valoda: eng
  • ISBN-13: 9780128039434
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3D Printing Applications in Cardiovascular Medicine addresses the rapidly growing field of additive fabrication within the medical field, in particular, focusing on cardiovascular medicine. To date, 3D printing of hearts and vascular systems has been largely reserved to anatomic reconstruction with no additional functionalities. However, 3D printing allows for functional, physiologic and bio-engineering of products to enhance diagnosis and treatment of cardiovascular disease. This book contains the state-of-the-art technologies and studies that demonstrate the utility of 3D printing for these purposes.

  • Addresses the novel technology and cardiac and vascular application of 3D printing
  • Features case studies and tips for applying 3D technology into clinical practice
  • Includes an accompanying website that provides 3D examples from cardiovascular clinicians, imagers, computer science and engineering experts
List of Contributors
xiii
Preface xvii
Acknowledgments xix
Introduction xxi
Chapter 1 History of 3D Printing
1(10)
Amanda Su
Subhi J. Al'Aref
Introduction to 3D Printing
1(1)
Early Research
1(1)
Beginning of 3D Printing
1(2)
Commercialization of 3D Printing
3(2)
3D Printing in Medicine
5(1)
Charles Hull
6(2)
References
8(3)
Chapter 2 3D Printing Methods
11(22)
Rami H. Awad
Sami A. Habash
Christopher J. Hansen
Introduction
11(3)
Overview of 3D Printing Process
11(1)
Processing Parameters Relevant to Cardiovascular Printing
12(2)
Digital Models
14(1)
Printing Methods
15(11)
Fused Deposition Modeling
15(3)
Selective Laser Sintering
18(2)
Direct Writing
20(2)
Stereolithography
22(2)
Material Jetting
24(2)
Summary
26(2)
References
28(5)
Chapter 3 Materials for 3D Printing Cardiovascular Devices
33(28)
Sanlin Robinson
Amir Hossein Kaboodrangi
Simon Dunham
Robert Shepherd
Introduction
33(18)
Synthetic Materials
34(1)
Commercial Material Systems
34(1)
Elastomers
35(3)
Hierarchical Materials
38(1)
3D Printing Actuators
39(2)
Bioprinting Materials
41(1)
Bioink Properties
41(2)
Bioinks
43(3)
Bioprinting Vasculature
46(5)
Conclusion
51(1)
References
51(10)
Chapter 4 Applications of 3D Printing
61(18)
Simon Dunham
Bobak Mosadegh
Eva A. Romito
Mohamed Zgaren
3D Printing for the Consumer Market
61(3)
3D Printing Edibles and the Food Industry
64(2)
Medical
66(2)
Industrial
68(1)
3D Bioprinting
69(2)
Potential of 3D Printing for Clothing and Accessories
71(3)
3D Printed Textiles
72(2)
3D Printed Fashion
74(1)
References
74(5)
Chapter 5 Complex Congenital Heart Disease
79(24)
Kevin Luke Tsai
Subhi J. Avaref
Alexander R. van Rosendael
Jeroen J. Bax
Introduction
79(1)
Cardiovascular Visualization
79(4)
Procedural Planning
83(1)
Examples of 3D Printing in Congenital Heart Disease
83(11)
Septal Defects
83(2)
Double Outlet Right Ventricle
85(1)
Transposition of the Great Arteries
86(3)
Tetralogy of Fallot
89(2)
Evaluation for Ventricular Assist Devices
91(1)
Evaluation for Heart Transplantation
92(2)
Use in Resource-Limited Environments
94(1)
Current Limitations
94(2)
The Future of Medical 3D Printing
96(1)
Conclusion
97(1)
References
98(5)
Chapter 6 Valvular Heart Disease
103(38)
Qusai Saleh
John Moscona
Thierry Le Jemtel
Introduction
103(1)
Imaging Considerations
104(1)
Applications in Valvular Heart Disease
105(1)
Aortic Valve Disease
105(8)
Anatomy of the Aortic Valve
107(2)
3D Printing Applications
109(4)
Mitral Valve Disease
113(13)
Anatomy of the Mitral Valve
114(3)
3D Printing Applications
117(9)
Tricuspid Valve Disease
126(3)
Anatomy of the Tricuspid Valve
128(1)
3D Printing Applications
128(1)
Pulmonary Valve Disease
129(2)
Development of Personalized Valvular Interventions
131(1)
References
131(10)
Chapter 7 Simulation of Percutaneous Structura Interventions
141(12)
Serge C. Harb
Brian P. Griffin
L. Leonardo Rodriguez
Introduction
141(1)
Simulation of Valvular Interventions
142(4)
Aortic Valve
142(1)
Mitral Valve
143(1)
Tricuspid Valve
143(2)
Pulmonary Valve
145(1)
Paravalvular Leaks
145(1)
Simulation of Congenital Interventions
146(1)
Simple Congenital Heart Defects
146(1)
Complex Congenital Heart Defects
146(1)
Simulation of Vascular Interventions
146(1)
Simulation of Miscellaneous Percutaneous Interventions
147(1)
Left Atrial Appendage Closure
147(1)
Hypertrophic Obstructive Cardiomyopathy
147(1)
Other Miscellaneous Applications
148(1)
Conclusion
148(1)
References
149(4)
Chapter 8 4D Printing of Actuating Cardiac Tissue
153(10)
Vahid Serpooshan
James B. Hu
Orlando Chirikian
Daniel A. Hu
Morteza Mahmoudi
Sean M. Wu
Introduction
153(6)
Temperature-Sensitive Materials
154(2)
Electrical-Sensitive (Conductive) Materials
156(1)
Cell-Traction Force-Sensitive Materials
157(2)
Bioengineering of Actuating Cardiac Tissues
159(1)
Conclusion
159(1)
References
160(2)
Further Reading
162(1)
Chapter 9 Bioprinting Cardiovascular Organs
163(26)
Yasin Hussain
Jonathan T. Butcher
Introduction
163(1)
Bioprinting Technologies
163(4)
Inkjet-Based Bioprinting
165(1)
Pressure/Extrusion-Based Bioprinting
165(1)
Laser-Assisted Bioprinting
166(1)
Stereolithography
166(1)
Bioinks
167(2)
Cell-Laden Hydrogels
167(1)
Cell Suspension
168(1)
Decellularized Extracellular Matrix
168(1)
Biomolecules
169(1)
Bioprinting Cardiovascular Tissue
169(11)
Cardiac Valves
169(1)
Aortic Valve Structure and Biomechanics
169(1)
Aortic Valve Constructs: Parameters for Bioprinting
170(1)
Examples of Bioprinting Aortic Valves
171(2)
Limitations
173(1)
Vasculature
174(1)
Structure and Function
174(1)
Bioprinting Vascular Constructs
174(1)
Scaffold-Based Indirect Vessel Bioprinting
175(1)
Scaffold-Based Direct Vessel Bioprinting
175(1)
Scaffold-Free Vessel Bioprinting
176(1)
Limitations
176(1)
Bioprinting of Myocardial Tissue and the Whole Heart
177(1)
Structure and Function
177(1)
Bioprinting Myocardial Constructs
178(1)
Bioprinting the Heart
178(2)
Limitations
180(1)
Future Directions
180(1)
References
180(9)
Chapter 10 Multimaterial Cardiovascular Printing
189(22)
Bobak Mosadegh
Ahmed Amro
Yazan Numan
Introduction
189(1)
Multimaterial Printing for Education and Communication
190(4)
Multimaterial Printing for Surgical Planning
194(2)
Multimaterial Printing of Valves
196(3)
Multimaterial Printing of Coronaries
199(2)
Multimaterial Printing of Cardiac Tissue
201(2)
Future Perspective of Multimaterial Printing for Cardiovascular Devices
203(2)
References
205(6)
Chapter 11 Assessing Perfusion Using 3D Bioprinting
211(16)
Hanley Ong
Kranthi K. Kolli
3D Bioprinting of Perfusable Vascular Networks
211(1)
Materials and Methods
212(6)
Innovations in Subtractive 3D Bioprinting of Vascularized Tissues
214(4)
Innovations in Additive 3D Bioprinting of Vascularized Tissues
218(1)
Applications in Transplantation and Regenerative Medicine
218(5)
Applications as Medical Research Models
223(1)
Future Directions
224(1)
References
225(2)
Chapter 12 Surgical Predictive Planning Using 3D Printing
227(16)
Muath Bishawi
Sreekanth Vemulapalli
Introduction
227(12)
Image Acquisition Modalities
229(1)
Current Applications of 3D Printing
230(7)
Future Developments in 3D Printing for Cardiac Surgery
237(2)
Conclusions
239(1)
References
239(4)
Chapter 13 The Future of 3D Printing in Cardiovascular Disease
243(12)
Mohamed B. Elshazly
Michael Hoosien
3D Printing as a Tool for Education and Simulation in Cardiovascular Medicine and Surgery
243(1)
3D Printing Clinical Applications in the Future of Cardiovascular Disease
244(4)
Structural Heart Disease Interventions
244(2)
Electrophysiology Applications
246(1)
Congenital Heart Disease
247(1)
Coronary and Systemic Vascular Disease
247(1)
Current Challenges and Future Directions of 3D Printing in Cardiovascular Disease
248(4)
Innovation in Image Acquisition and Post-Acquisition Processing
248(2)
Innovation in 3D Printing Materials
250(1)
Innovation in Bringing 3D Printing to Cardiovascular Clinical Practice
251(1)
Conclusion
252(1)
References
252(3)
Glossary 255(6)
Nomenclature 261(2)
Author Index 263(4)
Subject Index 267
Dr. James K. Min specializes in the diagnosis of coronary heart disease with multi-detector CT angiography. He also has expertise in the identification novel clinical risk factors that place individuals at higher risk for the development of coronary heart disease.

Between 2010-2014 Dr. Min published 197 publications, with 93.4% in the Medicine category. He has an h-index of 40. He has 3,910 citations, a 3.59 FWCI and averages 19.8 citations per publication during this same time frame. 49% of his publications appear in the top 10% most cited publications worldwide.

Dr . Min has experience with international, national, and institutional collaboration having worked with 150 co-authors. He also has experience with single authorship. Dr. Bobak Mosadegh uses interdisciplinary approaches to develop novel technologies for biomedical applications, particularly for cardiovascular diseases, cancer, and implantable/wearable therapeutics. His lab has specific interests in exploiting the properties of polymers and fluids to develop soft machines with integrated smart” behaviors. These soft machines use technologies related to microfluidics, soft robotics, and 3D cell culture. As of 2017, Dr. Mosadegh published 42 publications throughout various disciplines. He has an h-index of 28, and over 2500 citations. From 2010-2014, Dr. Mosadegh has a 2.75 FWCI and averages 16 citations per publication during this same time frame. 63.2% of his publications appear in the top 10% most cited publications worldwide. Dr. Mosadegh has experience with international, national, and institutional collaboration having worked with over 100 co-authors. Dr. Dunham's research centers on the development and testing of novel cardiovascular medical devices. His lab employs the use of soft materials, 3D printing, biomimicry, functional materials and flexible electronics to develop devices and tests methods with embedded functionality, sensing and other unique functionalities. Since joining the Dalio Institute for Cardiovascular Imaging at Weill Cornell Medicine, these efforts have been focused primarily on cardiovascular medicine. Between 2010-2014, Dr. Dunham published 12 papers across various disciplines. He has an h-index of 8 and 335 citations during that period of time. Dr. Subhi AlAref is an Instructor in Medicine and an Instructor of Medicine in Radiology at Weill Cornell Medicine and an Assistant Attending Physician at the NewYork-Presbyterian Hospital. Dr. AlAref was born and raised in Jerusalem, where he finished his primary and secondary education. He subsequently performed his premedical and medical training at Weill Cornell Medical College in Qatar, and earned his M.D. in 2008. He completed his training in Internal Medicine Residency, Cardiovascular Disease Fellowship, Interventional Cardiology and Preventative Cardiology at The NewYork-Presbyterian Hospital/Weill Cornell Medicine in New York City. He is board certified in Internal Medicine, Cardiovascular Disease, Interventional Cardiology, Vascular Medicine, Echocardiography and Nuclear Cardiology.
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