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This book discusses emerging approaches related to of 3D printing and bioprinting technologies in such areas as drug development, medical devices, and bioreactors. It offers an overview of applications, the market, and regulatory analysis.

The increasing availability and decreasing costs of 3D printing and bioprinting technologies are expanding opportunities to meet medical needs. 3D Printing and Bioprinting for Pharmaceutical and Medical Applications discusses emerging approaches related to these game-changer technologies in such areas as drug development, medical devices, and bioreactors.

Key Features:

  • Offers an overview of applications, the market, and regulatory analysis
  • Analyzes market research of 3D printing and bioprinting technologies
  • Reviews 3D printing of novel pharmaceutical dosage forms for personalized therapies and for medical devices, as well as the benefits of 3D printing for training purposes
  • Covers 3D bioprinting technology, including the design of polymers and decellularized matrices for bio-inks development, elaboration of 3D models for drug evaluation, and 3D bioprinting for musculoskeletal, cardiovascular, central nervous system, ocular, and skin applications
  • Provides risk-benefit analysis of each application
  • Highlights bioreactors, regulatory aspects, frontiers, and challenges

This book serves as an ideal reference for students, researchers, and professionals in materials science, bioengineering, the medical industry, and healthcare.

Chapter 1 3D Printing and Bioprinting Technologies in Pharmaceutics:
Commercial Perspectives and Market Analytics

Suihong Liu, Yakui Liu, Qingxi Hu, Haiguang Zhang, Jeong-Hui Park, Khandmaa
Dashnyam, Jung-Hwan Lee, Lijia Cheng, Zheng Shi, Barkan Kagan Durukan, Hilal
Turkoglu Sasmazel, Serge Ostrovidov, Hirokazu Kaji, Rouhollah Mehdinavaz
Aghdam, Alireza Jenabi, Mohammed Alqahtani, Mohamed Abbas, José Luis Pedraz
Muńoz, Seeram Ramakrishna, Hae-Won Kim, and Murugan Ramalingam

Chapter 2 3D Printing of New Drugs: Pharmaceutical Dosage Forms in
Personalised Therapies

Įlvaro Goyanes and Iria Seoane-Viańo

Chapter 3 3D Printing for In Vitro Drug Release Analysis and Cell Culture
Applications

Daniel Andrés Real, Marcelo Javier Kogan, Santiago Daniel Palma, and Juan
Pablo Real

Chapter 4 3D Printing of Medical Devices

Mary B. McGuckin, Achmad Himawan, Linlin Li, Jiaqi Gao, Qonita Kurnia Anjani,
Yara Naser, Ke Peng, Camila J. Picco, Anna Korelidou, Rand Ghanma, and Eneko
Larrańeta

Chapter 5 Polymers for Bioinks Development

Patricia Diaz-Rodriguez and Luis Diaz-Gomez

Chapter 6 Decellularized Matrices for Bioink Development

Daniel P. Reis, Luca Gasperini, and Alexandra P. Marques

Chapter 7 3D Bioprinting for Musculoskeletal Applications

Sandra Ruiz-Alonso, Fįtima Garcķa-Villén, Ilia Villate-Beitia, Fouad
Alhakim-Khalak, Jorge Ordoyo-Pascual, Lucķa Enriquez-Rodrķguez, Jon Zarate
Sesma, Gustavo Puras Ochoa, Laura Saenz Del Burgo Martķnez, and Jose Luis
Pedraz Muńoz

Chapter 8 3D Bioprinting for Cardiovascular Applications

N. Matthews, S. Ly, D. West, and C. Gentile

Chapter 9 3D Bioprinting for Central Nervous System Applications

Denis Scaini

Chapter 10 3D Bioprinting for Ocular Applications

Idoia Gallego, Markel Lafuente-Merchan, Myriam Sainz-Ramos, Ivįn Maldonado,
Jon Zarate Sesma, Laura Saenz del Burgo Martķnez, Gustavo Puras Ochoa, José
Luis Pedraz Muńoz, and Hodei Gómez-Fernįndez

Chapter 11 Bioreactors for Tendon Constructs

J. M. H. Spierings and J. Foolen

Chapter 12 Bioprinted Combined Medicinal Products: Regulatory Challenges for
Their Authorization and Commercialization

Eva Martķn-Becerra, Rossana Garcķa-Castro, and Ana Torres-Garcķa

Chapter 13 3D-Bioprinted Scaffold Technology to Promote Articular Cartilage
Regeneration in Osteoarthritis: An Example of Challenges of 3D Bioprinting

A. Mallick, V. Ward, M. B. OReilly, G. P. Duffy, and T. Mitra
José Luis Pedraz is Professor and principal researcher in the NanoBioCel group at the University of the Basque Country (UPV/EHU). The research group belongs to the CIBER-BBN of the Carlos III Health Institute, where he serves as the head and director of the medicine formulation laboratory (ICTS) Nanbiosis. Dr. Pedraz is also founder and director of the Pharmaceutical Development Unit of the Basque Country, currently TECNALIA Pharma Labs integrated in the TECNALIA Corporation within a joint project with the UPV/EHU, of which he is scientific director. He had a PhD in Pharmacy from the University of Salamanca.

Gustavo Puras is Professor at University of the Basque Country (UPV/EHU), Department of Pharmacy and Food Sciences. He is a member of the NanoBioCel research group at UPV/EHU and the National System of Researchers of Mexico (SNI). He is Professor in the Masters Program of Pharmacology, Development, Evaluation and Rational Use of Medicines at UPV/EHU. He received a PhD in Pharmacy from UPV/EHU.

Laura Saenz del Burgo is Professor at the University School of Nursing in Vitoria-Gasteiz and Associate Professor at University of the Basque Country (UPV/EHU) in the Department of Pharmacy and Food Sciences. She is a member of the NanoBioCel research group at UPV/EHU and part of the CIBER-BBN and gives technical assistance to the Nanbiosis platform (Drug Formulation). She received the PhD in Pharmacy from UPV/EHU and has worked as a postdoctoral researcher at the Institute of Molecular, Cell and Systems Biology, University of Glasgow.

Jon Zarate is Associate Professor, Department of Pharmacy and Food Sciences, Professor of the Doctoral Program in Drug Research and Evaluation, Application of Pharmaceutical Technology to the Development of Advanced Therapies, and Professor in the Masters Program in Pharmacology, Development, Evaluation and Rational Use of Medicines at University of the Basque Country (UPV/EHU). He is a member of the NanoBioCel research group at the same institution. He received a PhD in Pharmacy from UPV/EHU.