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Actinobacteria: Diversity and Biotechnological Applications: New and Future Developments in Microbial Biotechnology and Bioengineering [Mīkstie vāki]

Edited by (Associate Professor, Department of Agriculture & Environmental Sciences (AES), National Institute of Food Technology Entrepreneurship & Management (NIFTEM), An Institute of National Importance (INI), Haryana, India), Edited by , Edited by (Professor, AgroBio)
  • Formāts: Paperback / softback, 362 pages, height x width: 276x216 mm, weight: 1010 g
  • Izdošanas datums: 09-Feb-2018
  • Izdevniecība: Elsevier Science Ltd
  • ISBN-10: 0444639942
  • ISBN-13: 9780444639943
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Actinobacteria: Diversity and Biotechnological Applications: New and Future Developments in Microbial Biotechnology and BioengineeringPalielināt
  • Formāts: Paperback / softback, 362 pages, height x width: 276x216 mm, weight: 1010 g
  • Izdošanas datums: 09-Feb-2018
  • Izdevniecība: Elsevier Science Ltd
  • ISBN-10: 0444639942
  • ISBN-13: 9780444639943
Citas grāmatas par šo tēmu:
Permanent link: https://www.kriso.lv/db/9780444639943.html

Actinobacteria: Diversity and Biotechnological Applications: New and Future Developments in Microbial Biotechnology and Bioengineering, a volume in the series New and Future Developments in Microbial Biotechnology and Bioengineering series, offers the latest on the biotechnology of Kingdom actinobacteria, covering unique niches like their endosphere, rhizospheric soil and contaminated sites, etc. The book also covers the bioactive secondary metabolites obtained from actinobacteria and describes the application of microorganism (Actinobacteria) in plant growth promotion and in environmental cleanup. Finally, the book describes the biocontrol aspects of actinobacteria and how they can control fungal phytopathogens and the production of secondary metabolites.

  • Includes an overview of all types of actinobacteria, source and enzymatic activity
  • Lists various bioengineering methods for the production of these enzymes
  • Reviews numerous industrial applications of actinobacteria, i.e., crop improvement, removal of heavy metals, etc.
  • Offers unique coverage of the application of actinobacteria in bioremediation processes
  • Explores the plant growth promoting potential of endophytic actinobacteria
  • Describes biosynthetic potential genes associated with actinobacterial genome
List of Contributors
xiii
1 Methods Used for the Recovery of Culturable Endophytic Actinobacteria: An Overview
Ajit K. Passari
Vineet K. Mishra
Vijai K. Gupta
Bhim P. Singh
1.1 Introduction
1(1)
1.2 Isolation of Endophytic Actinobacteria
2(6)
1.2.1 Isolation Sources
2(1)
1.2.2 Isolation Procedure
2(4)
1.2.3 Media Used for Isolation of Actinobacteria
6(1)
1.2.4 Validation of Endophytic Actinobacteria
6(2)
1.3 Scanning Electron Microscope (SEM) Analysis
8(1)
1.4 Conclusion
8(5)
References
8(5)
2 Actinobacteria from Rhizosphere: Molecular Diversity, Distributions, and Potential Biotechnological Applications
Ajar Nath Yadav
Priyanka Verma
Sunil Kumar
Vinod Kumar
Manish Kumar
Thankappan Chellammal Kumari Sugitha
Bhim P. Singh
Anil Kumar Saxena
Harcharan Singh Dhaliwal
2.1 Introduction
13(1)
2.2 Isolation, Characterization, and Identification of Actinobacteria
14(3)
2.3 Diversity and Distribution of Actinobacteria
17(6)
2.4 Biotechnological Applications of Actinobacteria
23(10)
2.4.1 Direct Plant Growth Promotion
23(5)
2.4.2 Indirect Plant Growth Promotion
28(4)
2.4.3 Role of Actinobacteria for Biocontrol for Insect
32(1)
2.4.4 Actinobacteria for Human Health
33(1)
2.5 Conclusion and Future Prospects
33(10)
Acknowledgement
34(1)
References
34(9)
3 Molecular Markers Used for Identification and Genomic Profiling of Plant Associated Endophytic Actinobacteria
Ajit K. Passari
Vineet K. Mishra
Zothanpuia
Bhim P. Singh
3.1 Introduction
43(1)
3.2 Isolation of Endophytic Actinobacteria
44(1)
3.3 Morphological and Biochemical Identification of Endophytic Actinomycetes
44(1)
3.4 Molecular Characterization of Endophytic Actinomycetes Using Molecular Markers
45(1)
3.5 16S rRNA Gene Sequencing
46(2)
3.6 16S rRNA Restriction Fragment Length Polymorphism (16S rRNA-RFLP)
48(6)
3.7 Random Amplified Polymorphic DNA Polymerase Chain Reaction (RAPD-PCR)
54(3)
3.8 Repetitive Element Sequence (Rep) Based PCR (ERIC-PCR and BOX-PCR)
57(4)
3.9 Conclusion
61(6)
Acknowledgments
61(1)
References
61(4)
Further Reading
65(2)
4 Freshwater Actinobacteria: Potential Source for Natural Product Search and Discovery
Zothanpuia
Ajit K. Passari
Vincent V. Leo
Bhim P. Singh
4.1 Introduction to Actinobacteria
67(1)
4.2 Freshwater Actinobacteria
67(1)
4.3 Streptomyces: The dominant Genus
68(1)
4.4 Isolation of Freshwater Actinobacteria
69(1)
4.4.1 Pretreatment of Samples
69(1)
4.4.2 Heat Treatment
69(1)
4.4.3 Chemical Treatment
70(1)
4.5 Media for Isolation of Freshwater Actinobacteria
70(1)
4.6 Characterization of Freshwater Actinobacteria
70(4)
4.6.1 Morphological Characterization of Freshwater Actinobacteria
70(3)
4.6.2 Molecular Characterization of Actinobacteria
73(1)
4.7 Biotechnological Significance of Freshwater Actinobacteria
74(1)
4.7.1 Antimicrobial Potential of Freshwater Actinobacteria
74(1)
4.7.2 Enzymatic Activity of Freshwater Actinobacteria
74(1)
4.7.3 Secondary Metabolites From Freshwater Actinobacteria
74(1)
4.8 Biosynthetic (Secondary Metabolite) Genes From Freshwater Actinobacteria
75(1)
4.9 Conclusion
75(4)
References
75(2)
Further Reading
77(2)
5 Actinobacteria: Eco-Friendly Candidates for Control of Plant Diseases in a Sustainable Manner
Pooja Shrivastava
Rajesh Kumar
5.1 Introduction
79(1)
5.2 Actinobacteria as Plant Disease Suppressor
80(5)
5.2.1 Production of Agro-active Compounds (Antibiotics) and Volatiles by Actinobacteria
80(3)
5.2.2 Hyperparasitism/Mycoparasitisrn
83(1)
5.2.3 Competition and Rhizosphere Colonization
83(1)
5.2.4 Cell Wall Degrading (Hydrolytic) Enzymes
84(1)
5.2.5 Induction of Systemic Resistance
85(1)
5.3 Commercial Biocontrol Agents From Actinobacteria
85(1)
5.4 Merits of Actinobacterial BCAs
86(1)
5.5 Future Perspectives and Conclusion
86(7)
Acknowledgements
87(1)
References
87(4)
Further Reading
91(2)
6 Biocontrol Potential and Applications of Actinobacteria in Agriculture
Vivek Sharma
Richa Salwan
6.1 Introduction
93(1)
6.2 Actinobacterial Originated Bioformulations
94(1)
6.3 Biocontrol Mechanisms of Actinobacteria to Control Plant Diseases
94(1)
6.4 Rhizosphere Competence or Root Colonization
95(1)
6.5 Competition for Iron and the Role of Siderophores in Plant Growth and Development
95(2)
6.6 Phosphate Solubilization Potential of Actinobacteria
97(1)
6.7 Volatile Organic Compounds (VOCs) From Actinobacteria
97(1)
6.8 Antibiosis and Other Metabolites of Atinobacterial Origin
97(1)
6.9 Polyketide Synthesis by Actinobacteria
98(1)
6.10 Lytic Enzyme Production
99(2)
6.11 Growth Promotion
101(1)
6.12 Plant Immunity
101(1)
6.13 Application of Actinobacteria as Biocontrol
101(1)
6.13.1 Soil-Borne Diseases
102(1)
6.13.2 Foliar Diseases
102(1)
6.13.3 Vascular Wilt Diseases
102(1)
6.14 Insecticides Originated From Actiobacteria
102(1)
6.14.1 Nematode Control Potential
103(1)
6.15 Conclusion
103(6)
References
103(5)
Further Reading
108(1)
7 Endophytic Actinobacteria from Native Plants of Algerian Sahara: Potential Agents for Biocontrol and Promotion of Plant Growth
Yacine Goudjal
Miyada Zamoum
Nasserdine Sabaou
Abdelghani Zitouni
Van der Meer
7.1 Introduction
109(1)
7.2 Algerian Sahara and Its Native Plants: A Potential Source of Interesting Actinobacteria
110(1)
7.3 Isolation of Endophytic Actinobacteria
110(2)
7.4 Biocontrol and Plant Growth-Promoting Traits of Actinobacteria
112(4)
7.4.1 Antibiosis
112(1)
7.4.2 Lytic Enzymes
113(1)
7.4.3 Siderophore Production
113(1)
7.4.4 Solubilization of Inorganic Phosphate
113(1)
7.4.5 Colonization of Root Tissues
114(1)
7.4.6 Production of ACC-Deaminase
114(1)
7.4.7 Production of Phytohormones
115(1)
7.5 Endophytic Actinobacteria for Biocontrol and Plant Growth Promotion Applications
116(1)
7.6 Formulation of Biopesticides Based on Actinobacteria
117(2)
7.7 Conclusion
119(6)
References
120(5)
8 Streptomyces in Plant Growth Promotion: Mechanisms and Role
Natarajan Amaresan
Krishna Kumar
Jinal H. Naik
Kiran Gandhi Bapatla
Raj Kumar Mishra
8.1 Introduction
125(1)
8.2 Plant-Streptomyces Interaction
125(1)
8.3 Mechanism of Plant Growth Promotion
126(1)
8.4 Direct Mechanism
126(1)
8.4.1 Nitrogen Fixation
126(1)
8.4.2 Phosphate Solubilization
126(1)
8.4.3 Potassium Solubilization
127(1)
8.4.4 Production of Phytohormones
127(1)
8.5 Indirect Mechanism
127(3)
8.5.1 Antagonism
127(1)
8.5.2 Competition
128(1)
8.5.3 Siderophore Production
128(1)
8.5.4 Hydrogen Cyanide Production (HCN)
128(1)
8.5.5 Cell Wall Degrading Enzymes
128(1)
8.5.6 Antibiotic Production
129(1)
8.5.7 Induction of Host Resistance
129(1)
8.5.8 Abiotic Stress Management
129(1)
8.6 Commercial Streptomyces Biocontrol Agents
130(1)
8.7 Conclusion
130(7)
Acknowledgments
130(1)
References
130(5)
Further Reading
135(2)
9 Current Status and Applications of Actinobacteria in the Production of Anticancerous Compounds
Siddhardha Busi
Subha Swaraj Pattnaik
9.1 Introduction
137(1)
9.2 Trends in Drug Discovery Programmes
137(1)
9.3 Actinobacteria in Drug Discovery
138(1)
9.4 Anticancer Compounds From Actinobacteria
138(1)
9.5 Anticancer Compounds From Marine Derived Actinobacteria
139(4)
9.5.1 Anticancer Compounds From Marine Streptomyces
139(3)
9.5.2 Anticancer Compounds From Marine Micromonospora
142(1)
9.5.3 Anticancer Compounds From Marine Salinispora
142(1)
9.5.4 Anticancer Compounds From Marine Actinomadura
143(1)
9.5.5 Anticancer Compounds From Marine Nocardia
143(1)
9.6 Anticancer Compounds From Terrestrial Actinobacteria
143(1)
9.7 Antitumor Compounds From Actinobacteria
144(1)
9.8 Antitumor Compounds From Marine Derived Actinobacteria
144(1)
9.8.1 Polyketides
144(1)
9.8.2 Non Ribosomal Peptides
145(1)
9.8.3 Polyketide Peptides
145(1)
9.8.4 Isoprenoids
145(1)
9.8.5 Indolocarbazoles
145(1)
9.9 Antitumor Compounds From Terrestrial Actinobacteria
145(3)
9.10 Future Perspectives
148(1)
9.11 Conclusion
149(6)
References
149(6)
10 Biotechnological Potential of Thermophilic Actinobacteria Associated With Hot Springs
Amrita Kumari Panda
Satpal Singh Bisht
Mahendra Rana
Surajit De Mandal
Nachimuthu Senthil Kumar
10.1 Introduction
155(1)
10.1.1 The Phylum Actinobacteria
155(1)
10.1.2 Thermophilic Actinobacteria
156(1)
10.2 Isolation of Thermophilic Actinobacteria From Hot Springs
156(1)
10.3 Importance of Actinobacteria in the Hot Springs
156(1)
10.4 Bio-prospecting of Thermophilic Actinobacteria
156(5)
10.4.1 Industrially Important Enzymes
158(1)
10.4.2 Genetically Engineered Protein Production
158(1)
10.4.3 Biocontrol Agent
158(2)
10.4.4 Bioactive Compounds
160(1)
10.5 Conclusion
161(4)
Acknowledgments
161(1)
References
161(3)
Further Reading
164(1)
11 The Role of Actinobacteria in the Production of Industrial Enzymes
Richa Salwan
Vivek Sharma
11.1 Introduction
165(1)
11.2 Enzymes
165(1)
11.3 Amylases
166(1)
11.4 Lignocellulolytic Enzymes
166(3)
11.4.1 Lignolytic Enzymes
166(1)
11.4.2 Xylanases
167(1)
11.4.3 Cellulases
168(1)
11.4.4 Chitinases
168(1)
11.4.5 Proteases
169(1)
11.4.6 Lipase Enzyme
169(1)
11.5 Enzymes Used for Biotransformation/Modification of Natural Products
169(1)
11.5.1 Prenyltransferase
169(1)
11.5.2 Halogenase
170(1)
11.6 Other Industrial Applications of Actinomycetes
170(2)
11.6.1 Food Industry
170(1)
11.6.2 Leather Industry
170(1)
11.6.3 Detergent Industry
171(1)
11.6.4 Photographic Industry
171(1)
11.6.5 Pharmaceutical and Medical Applications
171(1)
11.6.6 Silk Degumming
171(1)
11.6.7 Bioremediation
172(1)
11.7 Conclusion and Future Prospects
172(7)
References
172(5)
Further Reading
177(2)
12 Characterization of the Genus Sinomonas: From Taxonomy to Applications
Manik Prabhu Narsing Rao
Min Xiao
Wen-Jun Li
12.1 Introduction
179(1)
12.2 History
179(2)
12.3 Morphological and Growth Conditions of Sinomonas Species
181(4)
12.4 Biochemical Characters of Sinomonas Species
185(1)
12.5 Chemotaxonomic and Molecular Characters of Sinomonas Species
185(3)
12.5.1 The Amino Acids and Sugars of Whole-Cell Hydrolysates
185(1)
12.5.2 Polar Lipids and Fatty Acids
185(1)
12.5.3 Respiratory Quinone and DNA G + C Contents
185(3)
12.6 Genome Sequences of Sinomonas Species
188(1)
12.7 Applications of the Genus Sinomonas
188(1)
12.8 Conclusion
189(2)
Acknowledgements
189(1)
References
189(2)
13 Actinobacteria: A Highly Potent Source for Holocellulose Degrading Enzymes
Vincent V. Leo
Dhaneswaree Asem
Zothanpuia
Bhim P. Singh
13.1 Introduction
191(1)
13.2 Actinobacterial Cellulases
192(3)
13.2.1 Exo-glucanase or Avicelase (EC 3.2.1.91)
192(1)
13.2.2 Endo-glucanase (EC 3.2.1.4)
193(1)
13.2.3 β-glucosidase (EC 3.2.1.21)
194(1)
13.3 Actinobacterial Hemicellulases
195(5)
13.3.1 Endo-1,4-β-xylanase (EC 3.2.1.8) and Acetyl Xylan Esterase (EC 3.1.1.72)
195(4)
13.3.2 Mannanase or β-Mannanase or endo-1,4-β-D-Mannanases (EC 3.2.1.78)
199(1)
13.4 Actinobacterial Dextranase (EC 3.2.1.11)
200(1)
13.5 Actinobacterial LPMO (CAZY-Auxiliary Activity Family 10)
200(1)
13.6 Conclusion
200(7)
Acknowledgment
202(1)
References
202(5)
14 Metabolic Potential and Biotechnological Importance of Plant Associated Endophytic Actinobacteria
Ashok Ganapathy
Sivakumar Natesan
14.1 Introduction
207(1)
14.2 Isolation of Endophytic Actinobacteria
208(1)
14.3 Identification and Molecular Characterization of Endophytic Actinobacteria
209(1)
14.4 Metabolic Potential of Endophytic Actinobacteria
210(8)
14.4.1 Endophytic Actinobacteria as Biological Control Agents
210(4)
14.4.2 Endophytic Actinobacteria as Plant Growth Promoting Agents
214(1)
14.4.3 Biotechnological Applications of Endophytic Actinobacteria
215(1)
14.4.4 Role of Endophytic Actinobacteria in Antibacterial Agents
215(1)
14.4.5 Biosynthetic Potential and Applications of Endophytic Actinobacterial Metabolites
216(2)
14.4.6 Role of Endophytic Actinobacteria in Bioremediation
218(1)
14.5 Conclusion
218(7)
Acknowledgements
218(1)
References
219(3)
Further Reading
222(3)
15 Biology of Pathogenic Actinobacteria: Nocardia and Allied Genera
Kiran Chawla
Peralam Y. Prakash
15.1 Introduction
225(1)
15.2 Taxonomy, Ecology, Structure
225(1)
15.3 Clinical Spectrum
225(3)
15.3.1 Pulmonary Manifestations
226(1)
15.3.2 Primary Cutaneous or Subcutaneous Infections
226(1)
15.3.3 Systemic Infections
226(2)
15.3.4 CNS Involvement
228(1)
15.4 Approaches for Identification
228(2)
15.5 Management of Nocardia and Other Actinobacteria Associated Infections
230(2)
15.5.1 Therapeutic Choices and Consideration
230(1)
15.5.2 Duration of Therapy and Progression
231(1)
15.5.3 Surgical Treatment
231(1)
15.6 Conclusion
232(3)
References
232(1)
Further Reading
233(2)
16 Novel Perspectives of Biotic and Abiotic Stress Tolerance Mechanism in Actinobacteria
Annavarapu Mohana Venkata Naga Prathyusha
Pallaval Veera Bramhachari
16.1 Introduction
235(1)
16.2 Actinobacterial Diversity in Rhizosphere
236(1)
16.3 Importance of PGPA in Sustainable Agricultural Production
236(1)
16.4 Portraying the Mechanistic Insights of PGPAs
237(1)
16.5 Functions of Actinobacteria in Sustainable Agriculture
238(3)
16.5.1 Alleviation of Plant Pathogen Stress by Actinobacteria
239(1)
16.5.2 Alleviation of Salt Stress by Actinobaceria
239(1)
16.5.3 Alleviation of Drought Stress by Actinobacteria
240(1)
16.5.4 Significance of Actinobacterial Metagenornics in Agricultural Research
240(1)
16.6 Conclusions and Future Perspectives
241(4)
Acknowledgment
241(1)
References
241(3)
Further Reading
244(1)
17 Detection and Expression of Biosynthetic Gene Clusters in Actinobacteria
Aleem B. Pinjari
Pallaval Veera Bramhachari
17.1 Introduction
245(1)
17.2 Biologically Active Secondary Metabolites From Actinobacteria
245(1)
17.2.1 Peptide Antibiotics
245(1)
17.2.2 Polyketides
246(1)
17.3 Biosynthetic Gene Clusters
246(5)
17.3.1 Detection of Biosynthetic Gene Clusters (BGCs)
246(2)
17.3.2 Expression of Biosynthetic Gene Clusters (BGCs)
248(3)
17.4 Conclusions and Future Perspectives
251(6)
Acknowledgement
251(1)
References
251(4)
Further Reading
255(2)
18 Recent Trends in Biosorption of Heavy Metals by Actinobacteria
Ashok Bankar
Geetha Nagaraja
18.1 Introduction
257(1)
18.2 Conventional Methods for Management of Heavy Metal Pollution
258(2)
18.2.1 Different Sources of Heavy Metals
258(1)
18.2.2 The Toxic Effects of Heavy Metals on Human Health
258(1)
18.2.3 Conventional Methods for Removal of Heavy Metals
259(1)
18.3 Biotechnological Approaches in Heavy Metal Bioremediation: Actinobacteria-Metal Interactions
260(10)
18.3.1 Heavy Metal Tolerance Mechanism(s) in Actinobacteria
260(2)
18.3.2 Bioaccumulation of Heavy Metals by Actinobacterial-Cells
262(1)
18.3.3 Advantages of Actinobacterial Biomass for Metal Biosorption
263(1)
18.3.4 Surface Characterization of Actinobacterial-Biornass
264(1)
18.3.5 Equilibrium Isotherms Models and Kinetics Models for Metal Adsorption by Actinobacterial-Biornass
265(1)
18.3.6 Biosorption Capacity of Actinobacterial-Biornass
266(4)
18.4 Conclusions
270(7)
Acknowledgments
271(1)
References
271(6)
19 Antimicrobial Compounds From Actinobacteria: Synthetic Pathways and Applications
Ekta Verma
Sindhunath Chakraborty
Balkrishna Tiwari
Arun Kumar Mishra
19.1 Introduction
277(1)
19.2 Actinobacteria and Their Environmental Distribution
277(4)
19.2.1 Actinobacteria
277(1)
19.2.2 Environmental Distribution of Actinobacteria
278(3)
19.3 Diversity and Applications of Actinobacterial Bioactive Compounds
281(1)
19.3.1 Antibacterial Compounds
281(1)
19.3.2 Antifungal Compounds
281(1)
19.3.3 Antiviral Compounds
282(1)
19.3.4 Anticancerous/Cytotoxic Compounds
282(1)
19.3.5 Biocontrol Agents
282(1)
19.4 Elicitation of Actinobacterial Bioactive Compounds
282(4)
19.4.1 Biological Process of Elicitation
283(2)
19.4.2 Chemical Process of Elicitation
285(1)
19.4.3 Molecular Method of Elicitation
286(1)
19.5 Biosynthesis of Antimicrobial Agents in Actinobacteria
286(3)
19.5.1 PKS Assembly Lines
287(1)
19.5.2 NRPS Assembly Lines
287(2)
19.5.3 PKS-NRPS Hybrid Assembly Lines
289(1)
19.5.4 Heterocyclization and Macrocyclization
289(1)
19.6 Summary
289(1)
19.7 Challenges and Future Prospect
289(8)
Acknowledgements
290(1)
References
290(5)
Further Reading
295(2)
20 Bio-Augmentation of Actinobacteria and Their Role in Dye Decolorization
Jamseel Moopantakath
Ranjith Kumavath
20.1 Introduction
297(1)
20.2 Textile Dyes and Their Importance
297(1)
20.2.1 Natural Dyes
297(1)
20.2.2 Synthetic Dye
298(1)
20.2.3 Textile Dye Act as a Xenobiotic
298(1)
20.3 Bio Magnifications
298(1)
20.4 Different Methods of Degradation
299(1)
20.5 Biodegradation of Azo Dye by Actinobacteria
299(1)
20.6 Enzymes Involved in the Biodegradation of Textile Dye by Actinobacteria
299(1)
20.7 Reductive Degradation of Textile Dye
300(1)
20.8 Oxidative Degradation of Azodyes
300(2)
20.9 Factors Effecting Biodegradation of Azo Dyes
302(1)
20.10 Future Prospectives of Actinobacteria Degradation
302(1)
20.11 Conclusion
302(3)
Acknowledgments
302(1)
References
302(2)
Further Reading
304(1)
21 Future Prospects of Actinobacteria in Health and Industry
Priyanka Sharma
Jintu Dutta
Debajit Thakur
21.1 Introduction
305(1)
21.2 Actinobacteria in Human Health
305(2)
21.3 Different Classes of Antibiotics From Actinobacteria
307(3)
21.3.1 β-lactam
307(2)
21.3.2 Aminoglycosides
309(1)
21.3.3 Chloramphenicol
309(1)
21.3.4 Tetracyclines
309(1)
21.3.5 Glycopeptide Antibiotics
309(1)
21.3.6 Macrolide-Lincosamide-Streptogramin B (MLS)
309(1)
21.3.7 Quinolone
310(1)
21.3.8 Sulphonamides
310(1)
21.4 Actinobacteria in Agriculture
310(2)
21.5 Actinobacteria in Nanotechnology
312(3)
21.6 Actinobacteria in Enzyme Industry
315(2)
21.7 Conclusion
317(8)
References
318(6)
Further Reading
324(1)
22 Genomics of Actinobacteria With a Focus on Natural Product Biosynthetic Genes
Pallaval Veera Bramhachari
Aleem Basha
Pinjari E. Kariali
22.1 Introduction
325(1)
22.2 Actinobacterial Genome
326(1)
22.3 Impact of Actinobacterial Natural Product Genomics
326(2)
22.4 Challenges in Actinobacterial Genomics
328(1)
22.5 Expression in Heterologous Hosts Versus Genome Mining
328(1)
22.6 CRISPR/Cas9 Genome Editing Technology
329(1)
22.7 Metagenomics-Driven Natural Product Discovery
329(1)
22.8 Computational Tools for Identification of BGCs in Streptomyces sp.
329(3)
22.8.1 Genome Mining Using Gene Specific Sequences
330(1)
22.8.2 Genome Mining Using Gene Specific Sequences
331(1)
22.8.3 Genome Mining Based on Phytogeny
331(1)
22.9 Conclusion and Future Prospects
332(5)
Acknowledgements
332(1)
References
332(3)
Further Reading
335(2)
Index 337
Dr. Singh is Associate Professor in the Department of Agriculture and Environmental Sciences at National Institute of Food Technology Entrepreneurship & Management (NIFTEM), An Institute of National Importance (INI), under the Ministry of Food Processing Industries, Government of India. Dr. Singh has obtained his Ph.D. from the Department of Biotechnology, Bundelkhand University, Jhansi, India while working in the Indian Agricultural Research Institute-National Bureau of Agriculturally Important Microorganisms (ICAR-NBAIM), Mau, India completed his post graduate training at the National Bureau of Plant Genetic Resources (ICAR-NBPGR), Pusa campus, New Delhi on Genetic Diversity of Barley Landraces by using RAPD markers. Dr. Singh has authored more than 100 research papers and book chapters in journals and books of international repute. Dr. Singh edited six books published by Springer and Elsevier. He is a member of the Association of Microbiologist of India (AMI), the Asian PGPR society for Sustainable Agriculture, the Mushroom Society of India (MSI), and the Indian Science Congress (ISC). He received several prestigious awards from agencies such as DST, New Delhi and other agencies in the field of Microbial Diversity. Dr Singh has served as guest editors in many journals like Frontiers in Microbiology, Biology-MDPI, Journal of Fungi-MDPI, Frontiers in Molecular biosciences etc. His major research areas are in postharvest disease management using natural agents and improving the shelf life of fresh commodities to reduce food loss happening during the food supply chain. Vijai K. Gupta has previously worked as- Senior Scientist, ERA Chair VALORTECH, Estonian University of Life Sciences, Estonia; Senior Scientist, ERA Chair Green Chemistry, Tallinn Technical University, Estonia and Senior Researcher, Molecular Glycobiotechnology Group Department of Biochemistry. NUI Galway Ireland. Currently, he working as Professor (Associate) of Biochemistry at UM6P University, Morocco. Dr. Guptas present work is focused on the development and optimization of novel enzyme-based bioconversion systems for biorefining and bioenergy, bioactive natural products and biomass to bioproduct valorisation using microbial technologies. He has 122 publications with h-index 36 and RG Score 41.25 Dr. Ajit Kumar Passari working as Postdoctoral Scientist in Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), México. Dr. Passari has more than eight years of research experience in the fields of Clinical, Genomics, Bioactive Compound Production, Agricultural Biotechnology, Plant-Microbe Interactions, Natural Product Isolation, PGPR, and biocontrol effect in crop plants. Dr. Passari obtained a doctorate in Biotechnology from the Department of Biotechnology, Mizoram University, India. Dr. Passari has published more than 50 publications in different reputed international and national journals along with many edited books published with Elsevier, Springer, etc. and he has also filled many patents in India. Dr. Passari has a life member of various scientific bodies like American Society of Microbiology (ASM), Microbiology Society & Indian Science Congress etc. Dr. Passari is a reviewer of different international journals including Nature-Scientific Reports, Frontiers in Microbiology, PLOS One, Biotechnology Reports and Applied Microbiology and Biotechnology.