This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
Chapter
1. An introduction to respiratory diseases and an emerging need
for efficient drug delivery systems.
Chapter
2. Inflammatory respiratory
diseases: Correlation between Lung cancer and CoVid-19.
Chapter
3.
Advancements in translational respiratory research using nanotechnology.-
Chapter
4. Chemical moieties as advanced therapeutics for targeting
respiratory disorders.
Chapter
5. Phytochemicals and their nanoformulations
targeted for pulmonary diseases.
Chapter
6. Nanocarriers: an advanced and
highly effective approach for targeting chronic lung diseases.
Chapter
7.
Vesicular drug delivery systems in respiratory diseases.
Chapter
8.
Nanoparticles in chronic respiratory diseases.
Chapter
9. Applications of
nanotechnology in pulmonary disease diagnosis.
Chapter
10. Nanotechnology in
pulmonary disease diagnosis.
Chapter
11. Recent trends in Nanomedicine for
diagnosis and treatment of pulmonary diseases.
Chapter
12. Strategies for
enhanced drug targeting to inflamed lungs: Novel perspectives.
Chapter
13.
Solid-Lipid Nanocarriers (SLNs) based drug delivery for treating various
pulmonary diseases.
Chapter
14. Microparticles, microspheres and
microemulsions as pulmonary drug delivery systems for the treatment of
respiratory diseases.
Chapter
15. Microparticles, microspheres and
microemulsions in respiratory diseases.
Chapter
16. Advanced drug delivery
systems targeting the immune system at cellular level in chronic respiratory
diseases.
Chapter
17. Targeted Micellar Systems for Pulmonary Disease
Intervention.
Chapter
18. Polymeric and inorganic nanoparticles targeting
chronic respiratory diseases.
Chapter
19. Mucoadhesive drug delivery system
in chronic respiratory diseases.
Chapter
20. Liposomal Drug Delivery:
Therapeutic Applications in Chronic Respiratory Diseases.
Chapter
21.
Biologics and vaccines for nasal and pulmonary drug delivery.
Chapter
22.
Drug delivery systems for respiratory infections.
Chapter
23. Cell and Gene
Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological
Trends and Advancements in Respiratory Medicine.
Chapter
24. Targeting
biofilms in respiratory diseases using novel drug delivery systems.
Chapter
25. Advanced nanomaterials for drug delivery in chronic respiratory
disorders.
Chapter
26. Emerging technological trends and advancements in
respiratory medicine.
Chapter
27. Pulmonary pharmacokinetics and
Biophysics.
Chapter
28. Clinical trials on novel advanced drugs for chronic
respiratory disorders.
DineshKumarChellappan currently works at the International Medical University (IMU), Kuala Lumpur, Malaysia. He has more than 12 years of teaching experience in the current profession. He completed his Ph.D. in Pharmaceutical Sciences, from the Manipal University, India, in 2009. Prior to that, he did his Masters in Pharmacy from the same university. He has worked on several research projects, especially in the field of diabetes and inflammation. He has published more than 1200 publications in reputed research journals with a cumulative impact factor of >2400. He also has presented a number of papers at conferences and has received research grants, both at national and international levels, to conduct research. In addition, heis a reviewer and is on the editorial board of several research journals. His area of expertise lies in the preparation of standardized plant extracts, isolation of phytoconstituents, characterization and structural elucidation of phytoconstituents, and pharmacological research of standardized extract for its various activities.
KavitaPabreja holds a Doctoral degree in Drug Discovery Biology from Monash Institute of Pharmaceutical Sciences, Monash University, Australia. Dr Pabrejas lecturing experience covers >5 years across national and international Universities, where she actively contributed to medical research and curriculum development. Her research experience includes >10 years of laboratory-based research focuse^21 original research and review articles in high-quality peer-reviewed journals. Currently, Dr Pabreja is utilizing her knowledge and skills in the role of Regulatory Affairs Coordinator with a leading Australian novel vaccine research company.
Md. Faiyazuddin has over 15 years of experience as an entrepreneur, academician, and researcher in the frontier areas of Pharmaceutical Sciences and Nanomedicine. Dr. Faiyazuddin is currently working as a Professor of Pharmaceutics with an additional charge of Dean Research & Development at Al - Karim University, Katihar, India. He served earlier as the Head of Asia Office and Global Business Director, Nano Drug Delivery®, Baltimore, USA. In recognition of his work, He was nominated as a Fellow member of the prestigious George Washington University USA for three years (2019 -2022). Most recently he earned Executive Degree in Strategic Leadership Management from the Jacobs-Abbey Global Institute for Leadership Studies, USA. He holds several leading positions including Principal InvestigatorNanopharmaceutical drug delivery research lab at the Integral University, Lucknow, Assistant Professor, and Quality CoordinatorCollege of Pharmacy, University of Hail, KSA, and Assistant Professor, Faculty of Pharmacy, Integral University, Lucknow, India. Dr. Faiyazuddin is the founder president of the International Pharmaceutical Forum. He is an associate member of the Institute of Nanotechnology, Scotland, British Society of Nanomedicine, International Society of Aerosol in Medicine, and American Lung Association, Chicago. He has made path-breaking contributions, particularly in Drug Delivery, Respiratory Nanomedicines, Onco-pharmaceuticals, Nanoemulsions, and Nanocarriers for Skin delivery. His research has received funding from the Department of Science & Technology, Govt. of India, the Deanship of Scientific Research, UoH, Saudi Arabia, and other foreign agencies. Dr. Faiyazuddin has published more than 70 peer-reviewed manuscripts in various international journals and has authored 4 books and 7 book chapters. He has a number of awards and accolades to his name. He is the organizing member of various international conferences in the Middle East and Europe. Dr. Faiyazuddin is editor of journals like Journal of Nanomedicine and Biotherapeutic Discovery, Pharmacologia, Intellectual Property Rights: Open Access, Clinical Research, and Regulatory Affairs, International Journal of Pharmacy Teaching and Practices, International Journal of Research in Pharmaceutical and Nano Sciences, and Journal of Basic and Applied Research.