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Advances in Chromatography: Volume 55 [Hardback]

Edited by , Edited by (Boehringer-Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA)
  • Formāts: Hardback, 250 pages, height x width: 234x156 mm, weight: 566 g, 13 Tables, black and white; 31 Line drawings, color; 58 Line drawings, black and white; 2 Halftones, color; 1 Halftones, black and white
  • Sērija : Advances in Chromatography
  • Izdošanas datums: 18-Dec-2017
  • Izdevniecība: CRC Press
  • ISBN-10: 1138068314
  • ISBN-13: 9781138068315
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Advances in Chromatography: Volume 55Palielināt
  • Formāts: Hardback, 250 pages, height x width: 234x156 mm, weight: 566 g, 13 Tables, black and white; 31 Line drawings, color; 58 Line drawings, black and white; 2 Halftones, color; 1 Halftones, black and white
  • Sērija : Advances in Chromatography
  • Izdošanas datums: 18-Dec-2017
  • Izdevniecība: CRC Press
  • ISBN-10: 1138068314
  • ISBN-13: 9781138068315
Citas grāmatas par šo tēmu:
Permanent link: https://www.kriso.lv/db/9781138068315.html
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For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 55, established, well-known chemists offer cutting-edge reviews of chromatographic methods to pay tribute to the late Eli Grushka, beloved series editor, who inspired and mentored many in the field of separation science. The clear presentation of topics and vivid illustrations for which this series has become known makes the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill.

Preface vii
Tributes for Eli Grushka ix
Contributors xvii
Chapter 1 A Study of Peak Capacity Optimization in One-Dimensional Gradient Elution Reversed-Phase Chromatography: A Memorial to Eli Grushka 1(22)
Peter W. Carr
Dwight R. Stoll
1.1 Introduction
1(1)
1.2 What Is Peak Capacity
2(3)
1.3 Limitations of the Peak Capacity Concept
5(2)
1.4 Gradient Elution Reversed-Phase Liquid Chromatography
7(4)
1.5 Speed in Liquid Chromatography and Optimization of Peak Capacity
11(5)
1.6 Effect of the Gradient Compression Factor on the Peak Capacity
16(3)
References
19(4)
Chapter 2 Laser Applications in Chromatography 23(28)
Anneli Kruve
Israel Schechter
2.1 Introduction
24(1)
2.2 Raman and Surface-Enhanced Raman Spectroscopies
25(26)
2.2.1 High-Performance Liquid Chromatography-Surface-Enhanced Raman Spectroscopy
26(3)
2.2.1.1 Fluorescence Interferences
26(1)
2.2.1.2 Mobile-Phase Interferences
26(1)
2.2.1.3 pH Interferences
27(1)
2.2.1.4 Online Coupling of Surface-Enhanced Raman Spectroscopy to High-Performance Liquid Chromatography
27(1)
2.2.1.5 Off-Line Coupling of Surface-Enhanced Raman Spectroscopy to High-Performance Liquid Chromatography
28(1)
2.2.1.6 Applications of High-Performance Liquid Chromatography-Surface-Enhanced Raman Spectroscopy
29(1)
2.2.1.7 Chemometric Methods for High-Performance Liquid Chromatography-Surface-Enhanced Raman Spectroscopy
29(1)
2.2.2 Thin-Layer Chromatography-Surface-Enhanced Raman Spectroscopy
29(3)
2.2.2.1 Thin-Layer Chromatography Plates Used in Thin-Layer Chromatography-Surface-Enhanced Raman Spectroscopy
29(1)
2.2.2.2 Application of Nanoparticles to Thin-Layer Chromatography Plates
30(1)
2.2.2.3 Dissolving of the Thin-Layer Chromatography Spots
30(1)
2.2.2.4 Dynamic Surface-Enhanced Raman Spectroscopy
30(1)
2.2.2.5 Applications of Thin-Layer Chromatography- Surface-Enhanced Raman Spectroscopy
30(2)
2.2.2.6 Quantification and Detection Limits
32(1)
2.2.2.7 Chemometric Methods for Thin-Layer Chromatography-Surface-Enhanced Raman Spectroscopy
32(1)
2.2.3 Alternative Methods
32(19)
Chapter 3 Hafnia and Zirconia Chromatographic Materials for the Enrichment of Phosphorylated Peptides 51(18)
Stefan Vujcic
Lisandra Santiago-Capeles
Karina M. Tirado-Gonzalez
Amaris C. Borges-Munoz
Luis A. Colon
3.1 Preamble by Luis A. Colon
51(1)
3.2 Introduction
52(2)
3.2.1 Enrichment of Phosphopeptides by Group IV Metal Oxides
53(1)
3.3 Tryptic Digest and Phosphopeptide Enrichment Procedures
54(1)
3.4 Hafnia and Zirconia Adsorptive Materials
55(1)
3.5 Enrichment of Bovine β-Casein Phosphopeptides on Zirconia and Hafnia Materials
55(10)
3.5.1 Electrospray Ionization-Mass Spectrometric Analysis
56(3)
3.5.2 Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight-Mass Spectrometric Analysis
59(6)
3.6 Final Remarks
65(1)
Acknowledgment
66(1)
References
66(3)
Chapter 4 Making Topipown Sequencing of All/Any Proteins a Reality. How Might This Be Accomplished? 69(18)
Ira S. Krull
Jared R. Auclair
4.1 Introduction and Background
70(1)
4.2 The Spaghetti Ball Analogy
70(4)
4.3 Sample Preparation
74(3)
4.3.1 Can the Right Solvents Help in Achieving 100% Sequence Coverage?
74(1)
4.3.2 Do Higher Charge States of Proteins Result in a Higher, Percent Sequence Coverage or Not? Supercharging versus Proton Transfer Reactions in the Gas Phase
74(2)
4.3.3 Would Pre-Mass Spectrometry, Chemical Derivatization Improve the Percent Sequence Coverage of Typical Proteins?
76(1)
4.4 Instrumental Parameters
77(6)
4.4.1 Can Source Parameters Be Realized and Maintained Throughout the Entire Mass Spectrometry to Increase Top-Down Sequencing?
77(1)
4.4.2 Ion Mobility Spectrometry and Collisional Cross Sections of Proteins versus Temperature
77(3)
4.4.3 How Can the Above-Mentioned Information Then Be Utilized to Improve All Future Top-Down Sequencing Studies?
80(2)
4.4.4 On Combining High Temperature, Differential Ion Mobility Spectrometry with Ultraviolet Photodissociation before MS-MS? How Else Can We Bring about Fragmentation of the Denatured Protein with Maximum Collisional Cross Sections?
82(1)
4.5 Conclusion
83(1)
Acknowledgments
83(1)
Abbreviations
83(1)
References
84(3)
Chapter 5 Is the Number of Peaks in a Chromatogram Always Less Than the Peak Capacity? A Study in Memory of Eli Grushka 87(18)
Joe M. Davis
Mark R. Schure
5.1 Introduction
87(1)
5.2 Background
88(2)
5.3 Theory
90(6)
5.3.1 Review of Statistical Overlap Theory
90(2)
5.3.2 Relative Values of p and n,
92(1)
5.3.3 Interpeak Statistics Functions
93(3)
5.4 Procedures
96(1)
5.5 Results and Discussion
96(5)
5.5.1 Relative Values of p and n,
97(3)
5.5.2 Trends
100(1)
5.6 Conclusion
101(1)
References
101(5)
Nonstandard Abbreviations
106
Chapter 6 Advances in Organic Polymer-Based Monolithic Columns for Liquid Phase Separation Techniques 105(80)
Ziad El Rassi
6.1 Introduction
107(1)
6.2 Polar Organic Monoliths
107(42)
6.2.1 Direct Copolymerization
108(22)
6.2.1.1 Nature of the Surface Charge
108(22)
6.2.2 Postpolymerization Functionalization
130(9)
6.2.2.1 Nature of the Surface Charge
131(8)
6.2.3 Monoliths with Incorporated Nanoparticles
139(4)
6.2.4 Ionic Liquid Monoliths
143(1)
6.2.5 Polar Organic-Silica Hybrid Monoliths
144(5)
6.3 Nonpolar Organic Monoliths
149(32)
6.3.1 Direct Copolymerization
150(10)
6.3.1.1 Poly Acrylate/Methacrylate-Based Monoliths
150(10)
6.3.1.2 Styrene Divinyl Benzene-Based Monoliths
160(1)
6.3.2 Cross-Linkers-Based Monoliths
160(3)
6.3.3 Nonclassical Polymerization Approaches and Novel Chemistries
163(5)
6.3.4 Postpolymerization Functionalization
168(3)
6.3.5 Monoliths with Incorporated Nanoparticles
171(5)
6.3.6 Ionic Liquid Immobilized Monoliths
176(2)
6.3.7 Nonpolar Hybrid Organic-Silica Monoliths
178(3)
6.4 Conclusion
181(1)
References
182(3)
Chapter 7 Solid-Core or Fully Porous Columns in Ultra High-Performance Liquid Chromatography-Which Way to Go for Better Efficiency of the Separation? 185(20)
Shulamit Levin
7.1 Introduction
185(1)
7.2 Ultra High-Performance Liquid Chromatography Emergence
186(4)
7.3 Efficiency of the Separation
190(6)
7.4 Reemergence of the Solid-Core Columns
196(1)
7.5 Theoretical Studies of the Extended Efficiency of Solid-Core Columns
197(4)
7.6 Conclusion
201(1)
References
201(4)
Chapter 8 Inverse Size-Exclusion Chromatography 205(24)
Annamdria Sepsey
Ivett Bacskay
Attila Felinger
8.1 Introduction
205(1)
8.2 Band Broadening Processes in Liquid Chromatography
206(2)
8.3 Distributions Contributing to Band Broadening
208(3)
8.3.1 Particle Size Distribution
208(1)
8.3.2 Pore Size Distribution
209(1)
8.3.3 Polydispersity
210(1)
8.4 Size-Exclusion Chromatography
211(3)
8.5 Inverse Size-Exclusion Chromatography
214(8)
8.5.1 Historical Perspectives
214(2)
8.5.2 Novel Model Based on the Stochastic Theory of Size-Exclusion Chromatography
216(6)
8.6 Conclusion
222(1)
References
222(7)
Chapter 9 Studies on the Antioxidant Activity of Foods and Food Ingredients by Thin-Layer Chromatography-Direct Bioautography with 2,2'-Diphenyl-l-Picrylhydrazyl Radical (DPPH) 229(16)
Joseph Sherma
9.1 Introduction
229(1)
9.2 Techniques of Thin-Layer Chromatography-2,2'Diphenyl-1- Picrylhydrazyl Radical
230(2)
9.3 Applications of Thin-Layer Chromatography-2,2'Diphenyl-1- Picrylhydrazyl Radical
232(8)
9.4 Future Prospects
240(1)
Acknowledgments
241(1)
References
241(4)
Index 245
Dr. Nelu Grinberg is a Distinguished Research Fellow in the Chemical Development Department at Boehringer Ingelheim Pharmaceuticals in Ridgefield, CT. Prior to this, he worked for sixteen years in the Analytical Department at Merck Research Laboratories in Rahway, NJ, where he was a Senior Research Fellow. He has authored and coauthored over 118 publications, including articles and book chapters. He is currently Editor and Chief of the Journal of Liquid Chromatography and Related Techniques, Editor of the book series Chromatographic Science Series, and Co-editor of the Advances in Chromatography series. He is also the President of the Connecticut Separation Science Council and a Koltoff fellow of the Hebrew University of Jerusalem. Dr. Grinberg obtained his Ph.D. in Chemistry from the Technical University of lasi in Romania. He conducted postdoctoral research with Professor Barry Karger at Northeastern University in Boston, Massachusetts, and with Professor Emanuel Gil-Av at The Weizmann Institute of Science in Rehovot, Israel.