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E-grāmata: Antimicrobial Stewardship

Edited by (Professor of Infectious Diseases and Clinical Microbiology, Koc University School of Medicine, Istanbul, Turkey), Edited by (Associate profess), Edited by , Edited by (Professor of Infectious Diseases, University of Lorraine, Nancy University Hospital, Nancy, France)
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Antimicrobials are the most commonly used drugs. Because of increasing resistance, the effective antimicrobials are becoming limited and this is an important cause of mortality and morbidity, that will become even more significant in the future. Accordingly, antimicrobial stewardship gained importance. Antimicrobial Stewardship (AMS) includes the experience of ESGAP workshops and courses on antibiotic stewardship since 2012. It combines clinical and laboratory information about AMS, with the focus on human medicine. The ESCMID study group on antibiotic policies (ESGAP) is one of the most productive groups in the field. The group organizes courses and workshops. Such a book will be an ideal tool for the participants of the workshop.

With short chapters (around 1500 words) written on different topics the authors insisted on the following points: - ‘hands on’, practical approach - tips to increase success - description of the most common mistakes - global picture (out- and inpatient settings, all countries) - short list of 10-20 landmark references

  • Focuses on the most recent AMS strategies
  • Provides a detailed description of laboratory support
  • Offers a balanced synthesis of basic and clinical sciences for each individual case, presenting clinical courses of the cases in parallel with the pathogenesis and detailed microbiological information for each infection
  • Describes the prevalence and incidence of the global issues and current therapeutic approaches
  • Presents the measures for infection control

Papildus informācija

Provides updated knowledge of bacterial resistance and recent developments in antimicrobial stewardship
Contributors xi
Foreword xv
Mario Poljak
Introduction xvii
Murat Akova
Introduction xix
Jesus Rodriguez-Bano
Introduction xxi
Evelina Tacconelli
Preface xxiii
Acknowledgments xxv
Section A The Global Picture of Antimicrobial Use and Resistance
1 The Global Crisis of Antimicrobial Resistance
3(10)
Tomislav Kostyanev
Fusun Can
2 Antimicrobial Stewardship: Efficacy and Implementation of Strategies to Address Antimicrobial Overuse and Resistance
13(16)
David X. Li
Sara E. Cosgrove
3 Quality Indicators and Quantity Metrics of Antibiotic Use
29(12)
Vera Vlahovic-Palcevski
Inge C. Gyssens
Section B AMS Strategies
4 Improving Antimicrobial Prescribing: Input from Behavioral Strategies and Quality Improvement Methods
41(14)
Marlies E.J.L. Hulscher
Jeroen Schouten
5 Education of Healthcare Professionals on Responsible Antimicrobial Prescribing
55(14)
Oliver J. Dyar
Bojana Beovic
6 Rapid Diagnostics and Biomarkers for Antimicrobial Stewardship
69(16)
Jose R. Pano Pardo
7 Pharmacokinetic and Pharmacodynamic Tools to Increase Efficacy
85(14)
Mahipal C. Sinnollareddy
Menino O. Cotta
Jason A. Roberts
8 The Use of Computerized Decision Support Systems to Support Antimicrobial Stewardship Programs
99(16)
Karin Thursky
9 The Role of Microbiology Laboratory in Promoting Antimicrobial Stewardship
115(14)
Fusun Can
Onur Karatuna
10 The Role of Pharmacists
129(10)
Philip Howard
11 The Roles of Nurses in Antimicrobial Stewardship
139(8)
Oliver J. Dyar
Celine Pulcini
12 Antifungal Stewardship
147(20)
Ozlem K. Azap
Onder Ergonul
Section C AMS in Specific Clinical Settings
13 Optimising Prescribing for Acute Respiratory Tract Infections as an Example for Antimicrobial Stewardship in Primary Care
167(8)
Femke Bohmer
Anja Wollny
Attila Altiner
14 Antimicrobial Stewardship: What to Tell the Patients and the General Public
175(10)
Vera Vlahovic-Palcevski
15 Antimicrobial Stewardship in Long-Term Care Facilities
185(8)
Celine Pulcini
16 Antimicrobial Stewardship in ICU
193(12)
Jeroen Schouten
Jan De Waele
17 Antimicrobial Stewardship in Hematology Patients
205(14)
Murat Akova
18 AMS in an Era of Multidrug-Resistant Bacteria
219(16)
Pilar Retamar
Jesus Rodriguez-Bano
Mical Paul
Khetam Hussein
Section D AMS Experiences Around the World
19.1 AMS Initiatives and Policies: The International Picture
235(4)
Bojana Beovic
Sara E. Cosgrove
19.2 Missions and Objectives of EUCIC and ESGAP
239(4)
Evelina Tacconelli
Bojana Beovic
19.3 Antimicrobial Stewardship in Latin America
243(4)
Gabriel Levy-Hara
Pilar Ramon-Pardo
Jose L. Castro
Cristhian Hernandez-Gomez
Luis Bavestrello
Maria V. Villegas
19.4 Antimicrobial Stewardship in Australia
247(4)
Kirsty Buising
Karin Thursky
19.5 Antimicrobial Stewardship in Austria
251(4)
Agnes Wechsler-Fordos
19.6 Antimicrobial Stewardship in Belgium
255(4)
Patrick Lacor
Peter Messiaen
19.7 Antimicrobial Stewardship in Bulgaria
259(4)
Emma Keuleyan
Tomislav Kostyanev
19.8 Antimicrobial Stewardship in Croatia
263(4)
Arjana Tambic Andrasevic
Vera Vlahovic-Palcevski
19.9 Antimicrobial Stewardship in England
267(4)
Philip Howard
19.10 Antimicrobial Stewardship in France
271(4)
Celine Pulcini
Guillaume Beraud
19.11 Antimicrobial Stewardship in Germany
275(6)
Katja de With
Winfried V. Kern
19.12 Antimicrobial Stewardship in Greece
281(4)
Antonis Valachis
Diamantis P. Kofteridis
19.13 Antimicrobial Stewardship in India
285(4)
Abdul Ghafur
19.14 Antimicrobial Stewardship in Israel
289(4)
Mitchell J. Schwaber
19.15 Antimicrobial Stewardship in Italy
293(4)
Leonardo Pagani
Pierluigi Viale
19.16 Antimicrobial Stewardship in Japan
297(2)
Keigo Shibayama
19.17 Antibiotic Stewardship in the Netherlands
299(2)
Inge C. Gyssens
Jan Prins
Jeroen Schouten
19.18 Antimicrobial Stewardship in Scotland
301(4)
Dilip Nathwani
Jacqueline Sneddon
19.19 Antimicrobial Stewardship in Slovenia
305(4)
Bojana Beovic
Milan Cizman
19.20 Antimicrobial Stewardship in South Africa
309(4)
Marc Mendelson
19.21 Antimicrobial Stewardship in Argentina
313(4)
Gabriel Levy-Hara
19.22 Antimicrobial Stewardship in Spain
317(4)
Jose R. Pano-Pardo
Jesus Rodriguez-Bano
19.23 Antibiotic Stewardship in Sweden
321(8)
Cecilia Stalsby Lundborg
Mats Erntell
Katarina Hedin
19.24 Antimicrobial Stewardship in Switzerland
329(2)
Catherine Pluss-Suard
Laurence Senn
Giorgio Zanetti
19.25 Antimicrobial Stewardship in Turkey
331(4)
Onder Ergonul
Fusun Can
Murat Akova
19.26 Antimicrobial Stewardship in the United States
335(6)
Theodore I. Markou
Sara E. Cosgrove
Section E Research and Perspectives
20 Methodological Challenges in Evaluating Antimicrobial Stewardship Programs: "Through Measuring to Knowledge"
341(20)
Marlieke E. A. de Kraker
Stephan Harbarth
Index 361(2)
List of Abbreviations 363
Céline Pulcini is Full Professor of Infectious Disease in Nancy, France. Her main research interest lies in antimicrobial stewardship and vaccination practices with the aim of preventing the emergence of bacterial resistance to antibiotics.

Professor Pulcini is Secretary of ESGAP, the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Antibiotic Policies. She is or has recently served also as Expert for the National Antibiotic Plan of the French Ministry of Health, the ECDC and the WHO. She is a member of the Executive Committee of the French Infectious Diseases Society (SPILF) and she coordinates the SPILF Antimicrobial Stewardship working group. In addition to this, Professor Pulcini is a partner in the European Innovative Medicines Initiative project DRIVE-AB.

As well as serving as an Associate Editor for the journal Clinical Microbiology and Infection, Professor Pulcini has also authored or co-authored over 130 international publications. She received in 2017 the ESCMID Young Investigator Award. Onder Ergonul, MD, MPH has been a professor of Infectious Diseases and Clinical Microbiology at Koē University, School of Medicine since 2011. He graduated from Hacettepe University School of Medicine in 1989 and completed his residency in 1996 in the Infectious Diseases and Clinical Microbiology department of Ankara University in Ankara, Turkey. He received his Master of Public Health degree from Harvard University School of Public Health in 2003. In 2000-2002, he worked as a research fellow in the Clinical Epidemiology division of the Infectious Diseases Department at the University of Utah, School of Medicine, USA. He is the editor of a book on Crimean-Congo Hemorrhagic Fever (2007, Springer). He received the Public Health Scientific award of Turkish Medical Association in 2007. He has been the president of the Turkish Society of Clinical Microbiology and Infectious Diseases since 2013. He has been the associate editor of Clinical Microbiology and Infection, official journal of the European Society of Clinical Microbiology and Infectious Diseases since 2013. He was elected as the member of Science Academy of Turkey in 2013. Fusun Can, MD Can is an associate professor of medical microbiology at the Koc University School of Medicine. She is specialized in the epidemiology of emerging bacterial pathogens, antibiotic resistance mechanisms and biofilm related infections. She graduated from Hacettepe University School of Medicine in 1989 and completed her residency in 1996 at Ankara University, Department of Microbiology and Clinical Microbiology in Ankara,Turkey. She worked as a research fellow in the Department of Microbiology at the University of Florida School of Medicine, USA. Before joining Koc University, she was the director of the Department of Medical Microbiology at Baskent University, in Ankara. She is responsible for the Microbiology and Biosafety Level III Laboratory at Koc University. Prof. Bojana Beovi, MD, PhD graduated at Medical School University in Ljubljana where she obtained her master degree and PhD. She was further educated in pharmacology at the University of Zagreb, Croatia and at The University of Wisconsin Hospital and Clinics.

From 2006 to 2009 she was the president of the Health Council at the Ministry of Health of Slovenia. From 2012 to 2017, she was the President of the Educational Council at the Medical Chamber of Slovenia. Currently, she is the head of the ID Consultancy Service at UMC Ljubljana, and vice chair of the Department of Infectious Diseases. Since 2004 she is the president of the Slovenian Society of Chemotherapy and since 2005 the vice-president of the Intersectoral Coordination Mechanism for Prudent Use of Antimicrobials at the Ministry of Health. Since 2008 she is the head of the Antibiotic Committee in UMC Ljubljana. Since 2015 she is the chair of the European Society of Clinical Microbiology and Infectious diseases (ESCMID) Study group for Antibiotic policies (ESGAP). She actively participates in several European level initiatives in the field of antimicrobial resistance and stewardship.

She is full professor of infectious diseases at the Medical School, University of Ljubljana. She was the organizer and co-organizer of several international and national scientific meetings and educational courses, and the author of several national antimicrobial guidelines and handbooks on antimicrobial therapy. Her current focus of interest in research is antibiotic stewardship, infections in surgery, and infections with multiple resistant bacteria.