Antimicrobials: Synthetic and Natural Compounds summarizes the latest research regarding the possibilities of the most important natural antimicrobial compounds derived from various plant sources containing a wide variety of secondary metabolites. With collected contributions from international subject experts, it focuses primarily on natural products as a source of bioactive compounds that may be active against multidrug-resistant pathogens, providing an alternative to established antibiotics in controlling infectious diseases.
Covering a wide range of marine, microbial, and plant-origin antimicrobials, the book examines the usefulness of plant products containing antimicrobial molecules against bacteria, fungi, protozoa, and viruses. It also reports on unusual sources of antimicrobials such as animal fecal actinomycetes, actinobacteria, and cyanobacteria and discusses synthetic chemical compounds and biogenic nanoparticles.
The number of drug-resistant bacteria is increasing, posing a major problem to modern medicine. This book explores an important topic: finding and applying alternative means of pathogenic control and treatment via natural sources. It is an important source of information for microbiologists, biotechnologists, biochemists, pharmacologists, botanists, marine biologists, and others involved in research on natural and synthetic antimicrobial compounds. It is also a useful resource for scholars, scientists, academics, and students in various science disciplines.
Recenzijas
"Antimicrobials is an eclectic collection of 25 chapters covering antimicrobial, anticancer, and antiviral drugs obtained from a vast array of natural environments and from traditional and microbe-mediated chemical synthetic approaches... Summing Up: Recommended. Graduate students, researchers/faculty, and professionals/practitioners." - M. S. Kainz, Ripon College, CHOICE, July 2016 Issue.
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| Editors |
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| Contributors |
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Chapter 1 Antibiotics: From discovery to journey |
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1 | (16) |
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Section I Broad spectrum antimicrobial compounds from microorganisms |
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Chapter 2 Antimicrobial potential of marine actinobacteria: A review |
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17 | (12) |
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Chapter 3 Antimicrobial compounds from microorganisms: Production, characterization, and applications |
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29 | (24) |
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Chapter 4 Animal fecal actinomycetes: A new source for the discovery of drug leads |
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53 | (30) |
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Chapter 5 Potentially novel Actinobacteria-derived antibiotics from unique microenvironments |
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83 | (16) |
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Chapter 6 Antimicrobial agents from actinomycetes: Chemistry and applications |
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99 | (18) |
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Chapter 7 Actinobacteria: A predominant source of antimicrobial compounds |
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117 | (26) |
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Chapter 8 Novel antimicrobial and anticancer drugs from bacteria |
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143 | (12) |
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Chapter 9 Bacteriocin: A natural alternative to synthetic antibacterial antibiotics |
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155 | (20) |
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Dharumadurai Dhanasekaran |
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Chapter 10 Protease inhibitors from marine organisms |
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175 | (14) |
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Chapter 11 Ganoderma: A bioresource of antimicrobials |
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189 | (14) |
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Dharumadurai Dhanasekaran |
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Chapter 12 Marine cyanobacteria: A prolific source of antimicrobial natural products |
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203 | (30) |
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Chapter 13 Antimicrobial and natural compounds from edible mushrooms |
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233 | (22) |
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Chapter 14 Aspergillosis and its resistance: Marine natural products as future treatment |
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255 | (24) |
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Dharumadurai Dhanasekaran |
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Section II Broad spectrum antimicrobial compounds from animals |
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Chapter 15 Secondary metabolites from microorganisms isolated from marine sponges from 2000 to 2012 |
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279 | (40) |
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Section III Broad spectrum antimicrobial compounds from plants and rhizosphere microorganisms |
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Chapter 16 Antimicrobial compounds and their chemical entities on therapeutic herbals for agricultural and medical applications |
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319 | (40) |
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Chapter 17 Role of antimicrobial compounds from Trichoderma spp. in plant disease management |
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359 | (12) |
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Chapter 18 Antimicrobial compounds from rhizosphere bacteria and their role in plant disease management |
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371 | (18) |
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Nallanchakravarthula Srivathsa |
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Section IV Synthetic chemical compounds as broad spectrum antimicrobials |
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Chapter 19 Microbe-mediated synthesis of silver nanoparticles: A new drug of choice against pathogenic microorganisms |
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389 | (14) |
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Chapter 20 Nanomaterials: Source of antimicrobial products |
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403 | (16) |
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Dharumadurai Dhanasekaran |
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Chapter 21 Platinum-based anticancer therapeutics and their mechanistic aspects: An overview |
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419 | (16) |
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Section V Narrow-spectrum antimicrobials |
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Chapter 22 Marine actinobacteria as potential drug storehouses: A future perspective on antituberculosis compounds |
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435 | (22) |
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Dharumadurai Dhanasekaran |
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Chapter 23 Antiprotozoal agents derived from natural soil and aquatic actinobacteria: Fighting one microbe with another |
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457 | (22) |
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Chapter 24 Bioactive compounds from actinomycetes and their antiviral properties: Present trends and future prospectives |
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479 | (8) |
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Chapter 25 Novel antidermatophytic drug candidates from nature |
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487 | (26) |
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| Index |
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Dharumadurai Dhanasekaran, PhD, is an Assistant Professor at Bharathidasan University, Tiruchirapalli, Tamil Nadu, India. He is experienced in actinobacteriology and mycology, with his current research focusing on actinobacteria, microalgae, fungi, and mushrooms for animal and human health improvement. He has deposited approximately 54 nucleotide sequences in GenBank, published 77 research and review articles and one book, and organized several national-level symposia, conferences, and workshops. He is a life member of the Mycological Society of India and the National Academy of Biological Sciences, is an editorial board member of national and international journals, and is a board of studies member in microbiology.
Nooruddin Thajuddin, PhD, is the Dean of the Faculty of Science, Engineering and Technology and the Head of the Department of Microbiology of the School of Life Sciences at Bharathidasan University, Tiruchirapalli, Tamil Nadu, India. He has vast experience in microbial taxonomy, isolation, cultivation, harvesting, and extraction of valuable products and is an expert in employing molecular tools in the identification and phylogeny of various microorganisms and bioremediation of effluents and bioenergy from microalgae and cyanobacteria. He has deposited about 475 nucleotide sequences in GenBank; has published 220 research and review articles and three books; has developed germplasm of cyanobacteria, microalgae, bacteria, actinobacteria, and fungi in his laboratory; and has organized several national-level symposia, workshops, refresher courses, and DST-INSPIRE programs. He is a life member of various academic bodies and an editorial board member of national and international journals.
Annamalai Panneerselvam, PhD, is an Associate Professor and the Head of the Department of Botany and Microbiology at AVVM Sri Pushpam College, Poondi, Tamil Nadu, India. He has more than 32 years of experience in teaching and
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