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Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance 2nd edition [Hardback]

(Steris Limited, Basingstoke)
  • Formāts: Hardback, 432 pages, height x width x depth: 257x180x25 mm, weight: 1111 g
  • Sērija : ASM Books
  • Izdošanas datums: 01-Oct-2017
  • Izdevniecība: American Society for Microbiology
  • ISBN-10: 1555819672
  • ISBN-13: 9781555819675
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  • Formāts: Hardback, 432 pages, height x width x depth: 257x180x25 mm, weight: 1111 g
  • Sērija : ASM Books
  • Izdošanas datums: 01-Oct-2017
  • Izdevniecība: American Society for Microbiology
  • ISBN-10: 1555819672
  • ISBN-13: 9781555819675
Citas grāmatas par šo tēmu:

The theory and practice of controlling and eliminating microorganisms

Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance by Gerald E. McDonnell is a detailed and accessible presentation of microbial control methods. Each major category, such as physical disinfection methods, is given a chapter, in which theory, spectrum of activity, advantages, disadvantages, and modes of action of the methods are thoroughly and clearly presented. Sufficient background on the life cycles and general anatomy of microorganisms is provided so that the reader who is new to microbiology will better appreciate how physical and chemical biocides work their magic on microbes. Topics covered include:• Evaluating the efficacy of chemical antiseptics and disinfectants, and of physical methods of microbial control and sterilization• How to choose the proper biocidal product and process for specific applications• Classic physical and chemical disinfection methods, such as heat, cold, non-ionizing radiation, acids, oxidizing agents, and metals• Newer chemical disinfectants, including isothiazolones, micro- and nano-particles, and bacteriophages as control agents• Antisepsis of skin and wounds and the biocides that can be used as antiseptics• Classic methods of physical sterilization along with newer methods, including the use of plasmaor pulsed light• Chemical sterilization methods that use ethylene oxide, formaldehyde, or a variety of other oxidizing agents• Modes of action of biocides in controlling microbial growth and disrupting microbial physiology• Mechanisms that microorganisms use to resist the effects of biocides

The second edition of Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance is well suited as a textbook and is outstanding as a reference book for facilities managers andapplication engineers in manufacturing plants, hospitals, and food production facilities. It is also essential for public health officials, health care professionals, and infection control practitioners.



The theory and practice of controlling and eliminating microorganisms

An examination of the various chemical and physical antisepsis, disinfection, and sterilization methods used for infection prevention and contamination control. Serves as a reference for microbiologists, chemists, facilities managers, health care professionals, infection and contamination control practitioners, application engineers, and students.
Preface xix
About the Author xxi
Chapter 1 Introduction
1.1 General introduction
1(1)
1.2 Definitions
2(4)
1.3 General microbiology
6(30)
1.3.1 Introduction
6(1)
1.3.2 Eukaryotes & prokaryotes
6(1)
1.3.3 Eukaryotes
6(8)
1.3.3.1 Multicellular eukaryotes
6(2)
1.3.3.2 Fungi
8(5)
1.3.3.3 Algae
13(1)
1.3.3.4 Protozoa
13(1)
1.3.4 Prokaryotes
14(14)
1.3.4.1 Eubacteria
14(12)
1.3.4.2 Archaea
26(2)
1.3.5 Viruses
28(5)
1.3.6 Prions
33(1)
1.3.7 Toxins
34(2)
1.4 General considerations
36(25)
1.4.1 Microbial resistance
36(2)
1.4.2 Evaluation of efficacy
38(12)
1.4.2.1 Suspension testing
38(5)
1.4.2.2 Surface testing
43(2)
1.4.2.3 In-use testing
45(1)
1.4.2.4 Biological, chemical, and other indicators
46(3)
1.4.2.5 Parametric control
49(1)
1.4.2.6 Microscopy and other techniques
49(1)
1.4.3 Disinfection versus sterilization
50(2)
1.4.4 Choosing a process or product
52(1)
1.4.5 Guidelines and standards
53(1)
1.4.6 Formulation effects
53(2)
1.4.7 Process effects
55(2)
1.4.8 The importance of surface cleaning
57(2)
1.4.9 Water quality
59(2)
Chapter 2 Physical Disinfection
2.1 Introduction
61(1)
2.2 Heat
61(7)
2.2.1 Types
61(2)
2.2.2 Applications
63(3)
2.2.3 Spectrum of activity
66(1)
2.2.4 Advantages
67(1)
2.2.5 Disadvantages
67(1)
2.2.6 Mode of action
68(1)
2.3 Cold temperatures
68(1)
2.4 Radiation
68(9)
2.4.1 Isotopes
68(1)
2.4.2 Electromagnetic radiation
69(2)
2.4.3 Types
71(2)
2.4.3.1 Ultraviolet
71(1)
2.4.3.2 Infrared
72(1)
2.4.3.3 Microwaves
72(1)
2.4.4 Applications
73(1)
2.4.4.1 UV
73(1)
2.4.4.2 Infrared
74(1)
2.4.4.3 Microwaves
74(1)
2.4.5 Spectrum of activity
74(1)
2.4.5.1 UV
74(1)
2.4.5.2 Infrared
75(1)
2.4.5.3 Microwaves
75(1)
2.4.6 Advantages
75(1)
2.4.6.1 UV
75(1)
2.4.6.2 Infrared
75(1)
2.4.6.3 Microwaves
75(1)
2.4.7 Disadvantages
76(1)
2.4.7.1 UV
76(1)
2.4.7.2 Infrared
76(1)
2.4.7.3 Microwaves
76(1)
2.4.8 Mode of action
76(1)
2.4.8.1 UV
76(1)
2.4.8.2 Infrared
77(1)
2.4.8.3 Microwaves
77(1)
2.5 Filtration
77(8)
2.5.1 Types and applications
77(5)
2.5.2 Spectrum of activity
82(2)
2.5.3 Advantages
84(1)
2.5.4 Disadvantages
84(1)
2.5.5 Mode of action
84(1)
Chapter 3 Chemical Disinfection
3.1 Introduction
85(1)
3.2 Acids and acid derivatives
85(4)
3.2.1 Types
85(2)
3.2.2 Applications
87(1)
3.2.3 Spectrum of activity
88(1)
3.2.4 Advantages
88(1)
3.2.5 Disadvantages
88(1)
3.2.6 Mode of action
89(1)
3.3 Alkalis or bases
89(2)
3.3.1 Types
89(1)
3.3.2 Applications
90(1)
3.3.3 Spectrum of activity
90(1)
3.3.4 Advantages
90(1)
3.3.5 Disadvantages
91(1)
3.3.6 Mode of action
91(1)
3.4 Aldehydes
91(6)
3.4.1 Types
91(1)
3.4.2 Applications
91(2)
3.4.2.1 Glutaraldehyde and OPA
91(1)
3.4.2.2 Formaldehyde
92(1)
3.4.3 Spectrum of activity
93(1)
3.4.3.1 Glutaraldehyde and OPA
93(1)
3.4.3.2 Formaldehyde
94(1)
3.4.4 Advantages
94(1)
3.4.4.1 Glutaraldehyde and OPA
94(1)
3.4.4.2 Formaldehyde
94(1)
3.4.5 Disadvantages
95(1)
3.4.5.1 Glutaraldehyde and OPA
95(1)
3.4.5.2 Formaldehyde
95(1)
3.4.6 Mode of action
95(2)
3.4.6.1 Glutaraldehyde and OPA
95(2)
3.4.6.2 Formaldehyde
97(1)
3.5 Alcohols
97(2)
3.5.1 Types
97(1)
3.5.2 Applications
97(1)
3.5.3 Spectrum of activity
98(1)
3.5.4 Advantages
98(1)
3.5.5 Disadvantages
99(1)
3.5.6 Mode of action
99(1)
3.6 Anilides
99(2)
3.6.1 Types
99(1)
3.6.2 Applications
100(1)
3.6.3 Spectrum of activity
100(1)
3.6.4 Advantages
100(1)
3.6.5 Disadvantages
100(1)
3.6.6 Mode of action
100(1)
3.7 Antimicrobial dyes
101(3)
3.7.1 Types
101(1)
3.7.2 Applications
101(1)
3.7.3 Spectrum of activity
102(1)
3.7.4 Advantages
103(1)
3.7.5 Disadvantages
103(1)
3.7.6 Mode of action
103(1)
3.8 Biguanides
104(3)
3.8.1 Types
104(1)
3.8.2 Applications
104(1)
3.8.3 Spectrum of activity
105(1)
3.8.4 Advantages
106(1)
3.8.5 Disadvantages
106(1)
3.8.6 Mode of action
106(1)
3.9 Diamidines
107(1)
3.9.1 Types
107(1)
3.9.2 Applications
107(1)
3.9.3 Spectrum of activity
107(1)
3.9.4 Advantages
108(1)
3.9.5 Disadvantages
108(1)
3.9.6 Mode of action
108(1)
3.10 Essential oils and plant extracts
108(3)
3.10.1 Types
108(1)
3.10.2 Applications
109(1)
3.10.3 Spectrum of activity
109(1)
3.10.4 Advantages
110(1)
3.10.5 Disadvantages
110(1)
3.10.6 Mode of action
110(1)
3.11 Halogens and halogen-releasing agents
111(10)
3.11.1 Types
111(4)
3.11.2 Applications
115(2)
3.11.2.1 Iodine
115(1)
3.11.2.2 Chlorine
116(1)
3.11.2.3 Bromine
117(1)
3.11.3 Spectrum of activity
117(1)
3.11.3.1 Iodine
117(1)
3.11.3.2 Chlorine
117(1)
3.11.3.3 Bromine
118(1)
3.11.4 Advantages
118(1)
3.11.4.1 Iodine
118(1)
3.11.4.2 Chlorine
118(1)
3.11.4.3 Bromine
118(1)
3.11.5 Disadvantages
119(1)
3.11.5.1 Iodine
119(1)
3.11.5.2 Chlorine
119(1)
3.11.5.3 Bromine
119(1)
3.11.6 Mode of action
120(1)
3.11.6.1 Iodine
120(1)
3.11.6.2 Chlorine
120(1)
3.11.6.3 Bromine
121(1)
3.12 Metals
121(5)
3.12.1 Types
121(1)
3.12.2 Applications
122(1)
3.12.2.1 Copper
122(1)
3.12.2.2 Silver
123(1)
3.12.3 Spectrum of activity
123(1)
3.12.3.1 Copper
123(1)
3.12.3.2 Silver
124(1)
3.12.4 Advantages
124(1)
3.12.4.1 Copper
124(1)
3.12.4.2 Silver
124(1)
3.12.5 Disadvantages
124(1)
3.12.5.1 Copper
124(1)
3.12.5.2 Silver
124(1)
3.12.6 Mode of action
125(1)
3.12.6.1 Copper
125(1)
3.12.6.2 Silver
125(1)
3.13 Peroxygens and other forms of oxygen
126(17)
3.13.1 Types
126(3)
3.13.2 Applications
129(7)
3.13.2.1 Ozone
129(1)
3.13.2.2 Hydrogen peroxide
130(4)
3.13.2.3 PAA
134(1)
3.13.2.4 Chlorine dioxide
135(1)
3.13.3 Spectrum of activity
136(3)
3.13.3.1 Ozone
136(1)
3.13.3.2 Hydrogen peroxide
137(1)
3.13.3.3 PAA
138(1)
3.13.3.4 Chlorine dioxide
139(1)
3.13.4 Advantages
139(1)
3.13.4.1 Ozone
139(1)
3.13.4.2 Hydrogen peroxide
139(1)
3.13.4.3 PAA
140(1)
3.13.4.4 Chlorine dioxide
140(1)
3.13.5 Disadvantages
140(2)
3.13.5.1 Ozone
140(1)
3.13.5.2 Hydrogen peroxide
140(1)
3.13.5.3 PAA
141(1)
3.13.5.4 Chlorine dioxide
141(1)
3.13.6 Mode of action
142(1)
3.13.6.1 Ozone
142(1)
3.13.6.2 Hydrogen peroxide
142(1)
3.13.6.3 PAA
143(1)
3.13.6.4 Chlorine dioxide
143(1)
3.14 Phenolics
143(4)
3.14.1 Types
144(1)
3.14.2 Applications
144(1)
3.14.3 Spectrum of activity
145(1)
3.14.4 Advantages
145(1)
3.14.5 Disadvantages
146(1)
3.14.6 Mode of action
146(1)
3.15 Antiseptic phenolics
147(8)
3.15.1 Types
147(1)
3.15.2 Applications
148(1)
3.15.3 Antimicrobial activity
149(1)
3.15.4 Advantages
150(1)
3.15.5 Disadvantages
151(1)
3.15.6 Mode of action
152(3)
3.15.6.1 Triclosan
152(2)
3.15.6.2 Chloroxylenol
154(1)
3.15.6.3 Salicylic acid
154(1)
3.16 Quaternary ammonium compounds and surfactants
155(4)
3.16.1 Types
155(1)
3.16.2 Applications
156(1)
3.16.3 Antimicrobial efficacy
157(1)
3.16.4 Advantages
158(1)
3.16.5 Disadvantages
158(1)
3.16.6 Mode of action
158(1)
3.17 Other miscellaneous biocides or applications
159(6)
3.17.1 Pyrithiones
159(1)
3.17.2 Isothiazolones derivatives
159(1)
3.17.3 Biocides integrated into surfaces
160(2)
3.17.4 Micro-or nano-particles
162(1)
3.17.5 Antimicrobial enzymes, proteins, or peptides
163(2)
3.17.6 Bacteriophages
165(2)
Chapter 4 Antiseptics and Antisepsis
4.1 Introduction
167(1)
4.2 Some definitions specific to antisepsis
167(1)
4.3 Structure of skin
168(1)
4.4 Skin microbiology
169(1)
4.5 Antiseptic applications
169(8)
4.5.1 Routine skin washing/antisepsis
170(3)
4.5.2 Pretreatment of skin prior to surgical intervention
173(1)
4.5.3 Treatment of skin or wound infections
174(3)
4.5.4 Treatment of oral and other mucous membranes
177(1)
4.5.5 Material-integrated applications
177(1)
4.6 Biocides used as antiseptics
177(8)
4.6.1 General considerations
177(3)
4.6.2 Major types of biocides in antiseptics
180(3)
4.6.3 Other antiseptic biocides
183(2)
Chapter 5 Physical Sterilization
5.1 Introduction
185(1)
5.2 Moist heat sterilization
185(12)
5.2.1 Types
187(5)
5.2.2 Applications
192(1)
5.2.3 Spectrum of activity
193(3)
5.2.4 Advantages
196(1)
5.2.5 Disadvantages
196(1)
5.2.6 Mode of action
197(1)
5.3 Dry heat sterilization
197(3)
5.3.1 Types
197(1)
5.3.2 Applications
198(1)
5.3.3 Spectrum of activity
199(1)
5.3.4 Advantages
199(1)
5.3.5 Disadvantages
199(1)
5.3.6 Mode of action
200(1)
5.4 Radiation sterilization
200(9)
5.4.1 Types
200(3)
5.4.2 Applications
203(3)
5.4.3 Spectrum of activity
206(2)
5.4.4 Advantages
208(1)
5.4.5 Disadvantages
208(1)
5.4.6 Mode of action
209(1)
5.5 Filtration
209(1)
5.6 Other physical sterilization methods
209(6)
5.6.1 Plasma
209(2)
5.6.2 Pulsed light
211(2)
5.6.3 Supercritical fluids
213(1)
5.6.4 Pulsed electric fields
214(1)
Chapter 6 Chemical Sterilization
6.1 Introduction
215(1)
6.2 Epoxides
215(7)
6.2.1 Types
216(1)
6.2.2 Applications
216(3)
6.2.3 Spectrum of activity
219(2)
6.2.4 Advantages
221(1)
6.2.5 Disadvantages
221(1)
6.2.6 Mode of action
222(1)
6.3 Low temperature steam-formaldehyde
222(3)
6.3.1 Types and applications
222(3)
6.3.2 Spectrum of activity
225(1)
6.3.3 Advantages
225(1)
6.3.4 Disadvantages
225(1)
6.3.5 Mode of action
225(1)
6.4 High temperature formaldehyde-alcohol
6.4.1 Types and applications
225(1)
6.4.2 Spectrum of activity
226(1)
6.4.3 Advantages
226(1)
6.4.4 Disadvantages
226(1)
6.4.5 Mode of action
226(1)
6.5 Hydrogen peroxide
226(7)
6.5.1 Types
226(2)
6.5.2 Applications
228(4)
6.5.3 Spectrum of activity
232(1)
6.5.4 Advantages
233(1)
6.5.5 Disadvantages
233(1)
6.5.6 Mode of action
233(1)
6.6 Other oxidizing agent-based processes
233(14)
6.6.1 Liquid peracetic acid
234(1)
6.6.2 Electrolyzed water
234(5)
6.6.2.1 Types
234(2)
6.6.2.2 Applications
236(1)
6.6.2.3 Spectrum of activity
237(1)
6.6.2.4 Advantages
237(1)
6.6.2.5 Disadvantages
238(1)
6.6.2.6 Mode of action
238(1)
6.6.3 Gaseous peracetic acid
239(1)
6.6.4 Ozone
240(2)
6.6.5 Chlorine dioxide
242(1)
6.6.6 Nitrogen dioxide
242(5)
Chapter 7 Mechanisms of Action
7.1 Introduction
247(1)
7.2 Anti-infectives
248(3)
7.2.1 Antibacterials (antibiotics)
248(3)
7.2.2 Antifungals
251(1)
7.2.3 Antivirals
251(1)
7.2.4 Antiparasitic drugs
251(1)
7.3 Macromolecular structure
251(4)
7.4 General mechanisms of action
255(30)
7.4.1 Introduction
255(2)
7.4.2 Oxidizing agents
257(6)
7.4.3 Cross-linking or coagulating agents
263(7)
7.4.4 Transfer of energy
270(6)
7.4.5 Other structure-disrupting agents
276(9)
Chapter 8 Mechanisms of Microbial Resistance
8.1 Introduction
285(1)
8.2 Biocide/Microorganism interaction
285(2)
8.3 Intrinsic bacterial resistance mechanisms
287(42)
8.3.1 General stationary phase phenomenon
288(1)
8.3.2 Motility and chemotaxis
289(1)
8.3.3 Stress responses
289(6)
8.3.4 Efflux mechanisms
295(4)
8.3.5 Enzymatic and chemical protection
299(1)
8.3.6 Intrinsic mechanisms to heavy metals
300(2)
8.3.7 Capsules, slime formation, and S-layers
302(2)
8.3.8 Biofilm development
304(6)
8.3.9 Bacteria with extreme intrinsic resistance
310(2)
8.3.10 Extremophiles
312(4)
8.3.11 Dormancy
316(11)
8.3.12 Revival mechanisms
327(2)
8.4 Intrinsic resistance of mycobacteria
329(4)
8.5 Intrinsic resistance of other Gram-positive bacteria
333(4)
8.6 Intrinsic resistance of Gram-negative bacteria
337(4)
8.7 Acquired bacterial resistance mechanisms
341(25)
8.7.1 Introduction
341(3)
8.7.2 Mutational resistance
344(11)
8.7.3 Plasmids and transmissible elements
355(11)
8.8 Mechanisms of viral resistance
366(6)
8.9 Mechanisms of prion resistance
372(4)
8.10 Mechanisms of fungal resistance
376(10)
8.11 Mechanisms of resistance in other eukaryotic microorganisms
386(7)
Index 393