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E-grāmata: Anxiety Disorders

Edited by (MD, Chief, Section on Development and Affective Neuroscience, Mood and Anxi), Edited by , Edited by (MD, PhD, Professor, Center for Behavioral Neuroscience, Department of Psychiatry and Behavioral Sciences, Yerkes Research Ctr, Emory University, Atlanta, GA)
  • Formāts: 448 pages
  • Sērija : Primer On
  • Izdošanas datums: 15-Apr-2015
  • Izdevniecība: Oxford University Press Inc
  • Valoda: eng
  • ISBN-13: 9780199395149
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  • Formāts: 448 pages
  • Sērija : Primer On
  • Izdošanas datums: 15-Apr-2015
  • Izdevniecība: Oxford University Press Inc
  • Valoda: eng
  • ISBN-13: 9780199395149
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Anxiety affects millions, manifesting as generalized anxiety disorder (GAD), obsessive compulsive disorder, panic disorder, phobias, post-traumatic-stress disorder (PTSD), and social anxiety disorder. Not only are anxiety disorders common, but they are also crippling, frequently co-occurring and predict high risk for depressive disorders. Shared mechanisms may explain the overlapping features of many anxiety disorders and account for associations with other highly-impairing conditions, such as major depression and substance use. Beyond risk for specific disorders, anxiety also predicts a number of other adverse outcomes, including suicidal behavior, medical problems, social, and economic difficulties. Conversely, disorder-specific mechanisms may also exist and explain the unique features of each syndrome. Thus, it is important to understand both shared and specific aspects of anxiety.

The Primer on Anxiety Disorders provides early-stage practitioners and trainees, as well as seasoned clinicians and researchers, with need-to-know knowledge on diagnosis and treatment. Clinical cases are used throughout the book to enhance understanding of and illustrate specific disorders, comorbid conditions and clinical issues. To facilitate an integrative approach, content allows clinicians to understand patient characteristics and tailor interventions. The integrated approach of each chapter includes recent research on genetics and neuroscience to understand the mechanisms of anxiety disorders, focusing on the forthcoming new nosology in DSM-5. Chapters further integrate innovative advances in clinical research providing research on a range of discoveries regarding biomarkers of illness, biological predictors of treatments and the effect of treatment on neurocircuitry.

Recenzijas

All clinicians and clinical scientists working in anxiety disorders who would like a vision of where the field will be in 5 to 10 years should read this Primer. With three of the leading clinical investigators in the world as Editors, and with a first-rate roster of contributors covering all the latest findings from neurotransmitter underpinnings of drug treatments to the neuroscience of psychological treatments, readers can preview likely changes in diagnosis, assessment, and treatment in the years to come. Most importantly, we get a glimpse of a future in which we can individualize treatment based on a sound set of scientifically validated predictors of outcome. A must read!" - David H. Barlow PhD, ABPP, Professor of Psychology and Psychiatry, Boston University, Founder and Director Emeritus, Center for Anxiety and Related Disorders, Boston, MA The study of anxiety, once the foundational concept for all psychopathology, maps the path for the future of all psychiatric neuroscience and psychobiology, revealing the rich interplay of nature, nurture and development, and yielding therapeutic advances in psychotherapies, psychopharmacology and neurotherapeutics. The publishers, editors and authors of this volume, and the pioneering organization that has brought them together, the ADAA, have delivered a comprehensive, essential and useful volume for the field." - Jerrold F. Rosenbaum, MD, Chief of Psychiatry, Massachusetts General Hospital; Stanley Cobb Professor of Psychiatry, Harvard Medical School, Boston, MA Among the book's many strengths are its readability, the focus on the important, need-to-know material, and comprehensive summaries of cited research. * Doody's Notes *

Foreword: Anxiety Disorders, Big Science, and Big Data: The Next Generation of Science and Practice ix
Terence M. Keane
Contributors xv
SECTION 1 OVERVIEW OF ANXIETY AND RELATED ILLNESSES
1 Anxiety and Related Disorders in DSM-5
3(14)
Dan J. Stein
2 Translational Perspectives on Anxiety Disorders and the Research Domain Criteria Construct of Potential Threat
17(16)
Isabelle M. Rosso
Daniel G. Dillon
Diego A. Pizzagalli
Scott L. Rauch
SECTION 2 NEUROBIOLOGY AND NEURAL CIRCUITRY OF ANXIETY DISORDERS
3 Neurobiology and Neuroimaging of Fear and Anxiety Circuitry
33(14)
K. Luan Phan
4 The Genetics of Anxiety Disorders
47(22)
Jordan W. Smoller
Felecia E. Cerrato
Sarah L. Weatherall
SECTION 3 DEVELOPMENT OF FEAR, FEAR PATHWAYS, AND ANXIETY DISORDERS IN CHILDREN AND ADOLESCENTS
5 Developmental Biology Related to Emotion and Anxiety
69(14)
Daniel S. Pine
6 The Development of Fear and Its Inhibition: Knowledge Gained from Preclinical Models
83(12)
Bridget L. Callaghan
Rick Richardson
7 Involving the Family in Treatment
95(10)
Karen Lynn Cassiday
8 Treating the College-age Patient
105(16)
Lisa R. Hale
Kathryn D. Kriegshauser
SECTION 4 POSTTRAUMATIC STRESS AND THE NEUROBIOLOGY OF TRAUMA
9 Neurobiology and Translational Approaches to Posttraumatic Stress Disorder
121(14)
Sheila A. M. Rauch
James L. Abelson
Arash Javanbakht
Israel Liberzon
10 Clinical Aspects of Trauma-related Anxiety and Posttraumatic Stress Disorder
135(18)
Andrew A. Cooper
Norah C. Feeny
Barbara O. Rothbaum
SECTION 5 OBSESSIVE COMPULSIVE AND DISORDERS OF CORTICAL-STRIATAL PROCESSING
11 Dissecting OCD Circuits: From Animal Models to Targeted Treatments
153(16)
Susanne E. Ahmari
Darin D. Dougherty
12 Clinical Aspects of Obsessive-Compulsive Disorder
169(20)
H. Blair Simpson
Edna B. Foa
SECTION 6 PHOBIAS, FEARS, AND PANIC
13 The Etiology of Fear and Anxiety: The Role of Environmental Exposures
189(12)
John M. Hettema
14 Clinical Aspects of Social Anxiety Disorder and Specific Phobias
201(12)
Franklin Schneier
Asala Halaj
15 Clinical Aspects of Panic Disorder
213(14)
Stefan G. Hofmann
SECTION 7 INTERSECTION OF MEDICAL AND ANXIETY DISORDERS
16 Fear, Anxiety Avoidance, and Chronic Pain
227(14)
Gordon J. G. Asmundson
Holly A. Parkerson
Christina A. D'Ambrosio
17 Detection and Treatment of Anxiety Disorders in Primary Care Settings
241(14)
Cara H. Fuchs
Risa B. Weisberg
18 Gastrointestinal Disorders, Irritable Bowel Syndrome, and Anxiety
255(12)
R. Bruce Lydiard
19 Anxiety Disorders and Cardiovascular Illness
267(16)
Michael J. Zvolensky
Jafar Bakhshaie
Charles Brandt
SECTION 8 INTERSECTION OF ANXIETY WITH MOOD AND SUBSTANCE DISORDERS
20 Substance Abuse and Comorbidity with Anxiety
283(16)
Jenna L. McCauley
Sudie E. Back
Kathleen T. Brady
21 Comorbidity of Anxiety and Depression
299(16)
Amanda W. Calkins
Andrew H. Rogers
Allison A. Campbell
Naomi M. Simon
22 Generalized Anxiety Disorder
315(14)
Emmanuel Garcia
Megan E. Renna
Douglas S. Mennin
23 Anxiety and Suicide
329(14)
Jessica D. Ribeiro
Matthew K. Nock
SECTION 9 COGNITIVE AND EXPOSURE-BASED TREATMENTS OF ANXIETY DISORDERS
24 Neural Circuit Mechanisms of Fear Extinction
343(12)
Blake L. Rosenbaum
Kara K. Cover
Huijin Song
Mohammed R. Milad
25 Learning Theory and Cognitive Behavioral Therapy
355(12)
Michael Treanor
Lindsay K. Staples-Bradley
Michelle G. Craske
26 Pharmacological Mechanisms of Modulating Fear and Extinction
367(22)
Boadie W. Dunlop
Kerry J. Ressler
Barbara O. Rothbaum
SECTION 10 NEUROTRANSMITTER PATHWAYS AND PHARMACOLOGICAL TREATMENTS OF ANXIETY DISORDERS
27 Stress, Anxiety, and Depression and the Role of Glutamate Neurotransmission
389(12)
Wendol Williams
Gerard Sanacora
28 The Role of the Hypothalamic--Pituitary--Adrenal Axis in Anxiety Disorders
401(12)
Luminita Luca
Charles B. Nemeroff
29 Pharmacological Interventions for Adult Anxiety Disorders
413(22)
Ryan J. Kimmel
Peter P. Roy-Byrne
SECTION 11 NEW TECHNOLOGIES AND APPROACHES TO TREATMENT
30 Adherence to Psychotherapy and Pharmacotherapy for Anxiety Disorders
435(18)
Alyson K. Zalta
Elizabeth C. Kaiser
Sheila M. Dowd
Mark H. Pollack
31 Computer Tools as Novel Treatment for Depression and Anxiety
453(10)
Anett Gyurak
Amit Etkin
32 Internet-Based Treatment for Anxiety and Obsessive-Compulsive and Related Disorders
463(12)
Christian Ruck
Erik Andersson
Erik Hedman
Index 475
Kerry J. Ressler, Professor of Psychiatry and Behavioral Sciences at Emory University, received his B.S. degree in molecular biology from M.I.T., and his M.D./Ph.D. from Harvard Medical School. His work focuses on translational research bridging molecular neurobiology in animal models with human genetic research. His basic and clinical research examines neurobiological, molecular, genetic and behavioral processes that underlie fear related processing and Posttraumatic Stress Disorder.

Dr. Daniel S. Pine is Chief, Section on Development and Affective Neuroscience, in the National Institute of Mental Health Intramural Research Program. Since graduating from medical school at the University of Chicago, Dr. Pine has been engaged continuously in research on pediatric mental disorders. Currently, his group examines the degree to which mood and anxiety disorders in children and adolescents are associated with abnormalities in the amygdala, prefrontal cortex, and brain regions that modulate these structures.

Barbara Olasov Rothbaum, Ph.D. is a professor in psychiatry and Associate Vice Chair of Clinical Research at the Emory School of Medicine in the Department of Psychiatry and Behavioral Sciences and director of the Trauma and Anxiety Recovery Program at Emory. Dr. Rothbaum specializes in research on the treatment of individuals with anxiety disorders, particularly focusing on Posttraumatic Stress Disorder (PTSD).