"This book is a pivotal reference source for the latest scholarly research on the progress of pharmaceutical design and computational approaches in the field of molecular docking, highlighting innovative research perspectives and real-world applications"--
Contributed by biochemists, biophysicists, and other scientists from Mexico, Asia, Iran, Ukraine, and the US, the 11 chapters in this volume discuss methodologies of molecular docking in drug design. They address the role of molecular docking in computer-aided drug design and development; the application of docking methodologies in quantitative structure activity relationship-based studies; the challenges and limitations of molecular docking; its application in studies on the binding mechanism of enzymes with natural products; docking of biologically active substances to double helical nucleic acids; rational drug design for the subtype selective G protein-coupled receptor ligands; molecular modeling, dynamics, and docking of membrane proteins; interactions and mutations in human toll-like receptor-4 and Ebola glycoprotein; molecular docking-based anti-allergic drug design; protein-protein interactions as an alternative to targeting the ATP binding site of kinase; and applications outside drug discovery. Annotation ©2016 Ringgold, Inc., Portland, OR (protoview.com)
As the pharmaceutical industry continues to advance, new techniques in drug design are emerging. In order to deliver optimum care to patients, the development of innovative pharmacological techniques has become a widely studied topic. Applied Case Studies and Solutions in Molecular Docking-Based Drug Design is a pivotal reference source for the latest scholarly research on the progress of pharmaceutical design and computational approaches in the field of molecular docking. Highlighting innovative research perspectives and real-world applications, this book is ideally designed for professionals, researchers, practitioners, and medical chemists actively involved in computational chemistry and pharmaceutical sciences.
