This book covers design and development of novel cost-effective aptamer-based biosensors for disease diagnostic and prognostic including understanding of health care management in terms of timely update of disease situation in a particular geographical area.
The design and fabrication of aptamer-based biosensors for point-of-care testing of disease diagnostic and prognostic is an upthrust and interdisciplinary area of research. This book covers the design and development of novel cost-effective aptamer-based biosensors for disease diagnostic and prognostic including an understanding of health care management in terms of timely updates of disease situations in a particular geographical area. It also discusses the scaling up and market trend of aptamer-based devices for extension of research from lab to market, and end users.
Features:
- Explains the design and fabrication of aptasensors-based diagnostic devices
- Includes novel approaches and comprehensive technology overview for diagnosis management towards early-stage detection of various biomarkers associated with several health conditions
- Demonstrates possible benefits of combined diagnostics and therapeutic possibilities using aptamer-based point-of-care technologies devices
- Discusses emerging implications and recent advances of biosensing platforms for designing and developing aptamer-based point-of-care testing (POCT) devices
- Explores aptamer-based approach to develop advanced platforms for medical applications and open arena for state-of-the-art future research
This book is aimed at researchers and graduate students in biomedical engineering, diagnostics, nanobiotechnology, and materials science.
1. Overview of aptamer-based biosensors
2. Biomarkers for aptamer-based
diagnostic applications
3. Designing and synthesis of aptamer via various
approaches (SELEX and ExSELEX)
4. A comparative study of aptasensor versus
immunosensor for biomarker detection
5. Aptamer-based point-of-care
diagnostic devices for infectious diseases
6. Aptamer-based colorimetric
biosensor
7. Aptamer beacon probes for the detection and visualization of
miRNA
8. Microfluidics-enabled aptamer-based sensing devices the
aptafluidics microdevices
9. Fabrication of aptamer-based electrochemical
biosensor for health care monitoring
10. Challenges and advances in
aptamer-based biosensing approaches
11. Current perspectives of aptasensors
as diagnostic tools for oncological diseases
Arpana Parihar is currently working as a Women Scientist B at CSIR- AMPRI, Bhopal, MP, India, under the scheme of DST-WoS-B awarded from the Department of Science and Technology, Government of India.
Raju Khan is currently working as a Principal Scientist and Associate Professor at CSIR-AMPRI Bhopal, Madhya Pradesh, India. He has more than 15 years of experience in electrochemistry, and development of biosensors-based diagnostics.