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Atlas of Lymph Node Pathology: A Pattern Based Approach [Hardback]

  • Formāts: Hardback, 320 pages, height x width: 276x213 mm, weight: 1043 g, 930
  • Izdošanas datums: 31-Dec-2020
  • Izdevniecība: Lippincott Williams and Wilkins
  • ISBN-10: 1496375548
  • ISBN-13: 9781496375544
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  • Formāts: Hardback, 320 pages, height x width: 276x213 mm, weight: 1043 g, 930
  • Izdošanas datums: 31-Dec-2020
  • Izdevniecība: Lippincott Williams and Wilkins
  • ISBN-10: 1496375548
  • ISBN-13: 9781496375544
Citas grāmatas par šo tēmu:
"Closely mirroring the daily sign-out process, Atlas of Lymph Node Pathology: A Pattern Based Approach is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily "scope-side guide," it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report. More than 1,500 high-quality photomicrographs depict reactive and neoplastic processes involving lymph nodes, capturing the full spectrum of morphologic changes associatedwith common abnormalities, including relatively rare conditions. Captions include a morphologic description, highlighting subtle features and key diagnostic considerations. Practical tools throughout the text include: Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options. Discussions of how and when to incorporate immunohistochemical and special stains, as well as the utilization of flow cytometry and molecular tools. Checklists for key elements of thediagnostic approach and sample notes for inclusion in pathology reports. Relevant endoscopic images, photographs of select gross specimens, and medical figures. Brief reviews of normal histology that provide contrast to succeeding patterns. "Pearls and Pitfalls" and "Near Misses" sections with lessons from real-life sign-out experience . "Frequently Asked Questions" sections that discuss common diagnostic dilemmas. "Sample Note" sections that offer a template of how to synthesize complicated or especially challenging topicsQuizzes in every chapter that provide experience with high-yield, board-style teaching topics"--

Closely mirroring the daily sign-out process, Atlas of Lymph Node Pathology: A Pattern Based Approach is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily &;scope-side guide,&; it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report.
  • More than 1,500 high-quality photomicrographs depict reactive and neoplastic processes involving lymph nodes, capturing the full spectrum of morphologic changes associated with common abnormalities, including relatively rare conditions. Captions include a morphologic description, highlighting subtle features and key diagnostic considerations.
  • Practical tools throughout the text include:
    • Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options
    • Discussions of how and when to incorporate immunohistochemical and special stains, as well as the utilization of flow cytometry and molecular tools
    • Checklists for key elements of the diagnostic approach and sample notes for inclusion in pathology reports
    • Relevant endoscopic images, photographs of select gross specimens, and medical figures
    • Brief reviews of normal histology that provide contrast to succeeding patterns
    • &;Pearls and Pitfalls&; and &;Near Misses&; sections with lessons from real-life sign-out experience            
    • &;Frequently Asked Questions&; sections that discuss common diagnostic dilemmas   
    • &;Sample Note&; sections that offer a template of how to synthesize complicated or especially challenging topics
    • Quizzes in every chapter that provide experience with high-yield, board-style teaching topics  

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Closely mirroring the daily sign-out process, Atlas of Lymph Node Pathology: A Pattern Based Approach is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily &;scope-side guide,&; it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report.
1 Introduction To The Lymph Node
1(36)
Lymph Node Structure
2(10)
Capsule
2(1)
Sinuses
2(1)
Cortex
3(5)
Paracortex
8(1)
Medulla
9(3)
Specimen Preparation
12(5)
Fixation
12(1)
Frozen Sections
12(2)
Limited Specimens
14(3)
Clinical Context
17(3)
Anatomic Site
17(1)
Patient Demographics
17(1)
Clinical Information
17(3)
Ancillary Studies
20(5)
Flow Cytometry
20(3)
Cytogenetic/FISH Studies
23(1)
Molecular Studies
23(2)
Near Misses
25(12)
IgG4-Reactive Lymphadenopathy
25(1)
Nodal Marginal Zone B-Cell Lymphoma With Colonization of Reactive Follicles
25(2)
Intrafollicular Neoplasia
27(4)
Interfollicular Classical Hodgkin Lymphoma
31(1)
Early Angioimmunoblastic T-cell Lymphoma
31(6)
2 The Lymph Node Capsule
37(26)
Normal Lymph Node Capsule
38(1)
Absent Capsule
38(1)
Lymph Node Versus Lymphoid Tissue
38(1)
Capsular Inclusions
38(1)
Disrupted Capsule
39(1)
Thickened Capsule
40(15)
Reactive Conditions
40(9)
Neoplastic Conditions
49(6)
Near Misses
55(8)
Angioimmunoblastic T-cell Lymphoma
55(1)
Kaposi Sarcoma
55(2)
Tumor-Infiltrating Lymphocytes Versus Metastatic Disease
57(1)
Capsular Nevi Versus Metastatic Melanoma
57(6)
3 The Lymphatic Sinuses
63(22)
Introduction
64(1)
Conditions With Dilated Prominent Sinuses
64(5)
Sinus Histiocytosis and Dermatopathic Lymphadenopathy
64(1)
Sinus Histiocytosis With Massive Lymphadenopathy (SHML)
65(1)
Langerhans Cell Histiocytosis (LCH)
65(1)
Lymphoplasmacytic Lymphoma
66(1)
Node Draining Suppurative Area
67(1)
Lipid-Associated Lymphadenopathy (Lymphangiogram, Prosthesis, or Storage Diseases)
67(1)
Vascular Transformation of Sinuses
68(1)
Near Miss
69(1)
Sinusoidal Involvement by Kaposi Sarcoma Mimicking Vascular Transformation of Sinuses
69(1)
Sinusoidal Lymphomatous Infiltrates
69(1)
Near Miss
70(5)
ALCL Mimicking Metastatic Carcinoma
70(4)
Metastatic Cancer
74(1)
Near Miss
75(2)
Benign Mesothelial Cells
75(1)
Leukemic Infiltrates
75(1)
Other Perisinusoidal Cellular Clusters
76(1)
Conditions With Inconspicuous/Obliterated Sinuses
77(8)
Follicular Lymphoma
77(2)
Castleman Disease
79(1)
Angioimmunoblastic T-cell Lymphoma
80(5)
4 Cortex
85(22)
Introduction
86(1)
Clinical Correlation
86(1)
Site-Specific Variations in Follicles
86(1)
Abnormal Follicles
87(9)
Reactive Follicular Hyperplasia
87(1)
Giant Follicular Hyperplasia
88(4)
Reactive Follicular Hyperplasia In Altered Immune States
92(1)
Intrafollicular Plasmacytosis-IgG4 Disease
93(2)
Other Clonal Conditions With Reactive Hyperplasia
95(1)
Abnormal Expanded Mantle Zones
96(6)
Castleman-Like Proliferations
96(3)
Progressive Transformation of Germinal Centers
99(2)
Kimura Disease
101(1)
Attenuated Mantle Zones
102(1)
Other Infectious Processes
102(5)
Toxoplasma
102(5)
5 Paracortex
107(48)
Paracortical Hyperplasia
108(15)
Dermatopathic Lymphadenopathy
108(3)
Infection
111(9)
Drug-Associated Lymphadenopathy
120(2)
Autoimmune Conditions
122(1)
Systemic Lupus Erythematosus Lymphadenopathy
122(1)
Atypical Paracortical Hyperplasia
122(1)
Histiocytic Proliferations
123(7)
Singly/Small Clusters
123(4)
Granulomas
127(1)
Extensive/Diffuse
127(3)
Vascular Changes
130(5)
Vascular Proliferation
130(5)
Abnormalities of Vessel Walls
135(1)
Expansion/Infiltration of the Paracortex by Unexpected Cells
135(11)
Atypical Lymphocytes/Lymphomas
137(1)
Plasma Cells
137(7)
Spindled Cells
144(2)
Necrosis
146(1)
Near Misses
146(9)
Hamazaki-Wesenberg Bodies in Sarcoidosis Lymphadenopathy
146(2)
Indolent "[ "-Lymphoblastic Proliferation
148(1)
Lymph Node Involvement by Myeloid/Lymphoid Neoplasms With PDGFRA Rearrangement
148(7)
6 Obliterated Nodular Pattern
155(24)
Introduction
156(1)
List of Entities to Consider in Cases With Nodular Pattern
156(1)
Follicular lymphoma
157(11)
Some Histologic Variations That Represent Pitfalls in the Diagnosis of Follicular Lymphoma
157(5)
Grading and Follicular Lymphoma
162(3)
Unconventional Wisdom Relating to FL Grading
165(3)
Immunostains and Approach in Nodular Proliferations
168(5)
Scenarios and Clinical Details That Determine How You Look at and Sign Out Some Follicular Lymphoma Cases
172(1)
Pitfall Cases of Nodular Proliferations
173(6)
Pitfall Case 1: Nodal Marginal Zone lymphoma with Follicular Colonization
173(2)
Pitfall Case 2: Germinotropic lymphoproliferative disorder, EBV+/ HHV8+
175(1)
Pitfall Case 3: Follicular variant of peripheral T-cell lymphoma (Figures 6.66-6.70)
176(3)
7 Obliterated Nodal Architecture
179(42)
B-Cell Lymphomas
180(18)
Small Lymphocytic Lymphoma and Richter Syndrome
180(3)
Mantle Cell Lymphoma
183(1)
Diffuse Follicular Lymphoma
183(2)
Follicular Lymphoma With Transformation to DLBCL
185(1)
Plasmacytoma/Plasma Cell Myeloma
186(1)
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
187(1)
T-Cell-/Histiocyte-Rich Large B-Cell Lymphoma
188(1)
Plasmablastic Lymphoma
189(3)
Primary Mediastinal Large B-Cell Lymphoma
192(1)
B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classical Hodgkin Lymphoma (Gray Zone Lymphoma)
192(1)
Burkitt Lymphoma
192(1)
High-Grade B-Cell Lymphoma
193(5)
T-Cell Lymphomas
198(8)
Anaplastic Large-Cell Lymphoma
198(1)
Peripheral T-Cell Lymphoma
198(4)
Lymphoepithelioid Variant of PTCL (Lennert Lymphoma)
202(4)
Precursor Lesion
206(3)
Myeloid Sarcoma
206(3)
B-Lymphoblastic Lymphoma
209(1)
T-Lymphoblastic Lymphoma
209(1)
Near Misses
209(12)
Blastoid Variant of Mantle Cell Lymphoma
209(4)
Nodal Involvement by CD30-Positive T-Cell Lymphoproliferative Disorder
213(1)
Peripheral T-Cell Lymphoma With Hodgkin-Like Cells
213(3)
Anaplastic Large-Cell Lymphoma With Aberrant Expression of PAX5
216(5)
8 Necrosis
221(20)
Introduction
222(1)
Lymphoma/Aggressive Lymphoproliferative Neoplasms
222(1)
B-Cell Lymphoma
222(1)
B Lymphoblastic Lymphoma
222(6)
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
223(1)
EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
223(2)
Post-Transplant Lymphoproliferative Disorder
225(2)
Plasmablastic Lymphoma
227(1)
Classical Hodgkin Lymphoma
228(1)
T-Cell and NK Cell Lymphoma
228(1)
Peripheral T-Cell Lymphoma, Not Otherwise Specified
228(1)
NK/T-Cell Lymphoma
228(1)
Anaplastic Large Cell Lymphoma
229(3)
Infectious Etiologies
232(4)
Mycobacterial Lymphadenitis
232(1)
Cytomegalovirus Infection
233(1)
Herpes Simplex Lymphadenitis
233(1)
Cat Scratch Disease
233(1)
Fungal Infection/Lymphadenitis
234(2)
Benign Reactive Lymphoproliferative Disorders
236(1)
Systemic Lupus Erythematosus
236(1)
Near Misses
236(5)
Epstein-Barr Virus: Infectious Mononucleosis
236(1)
Kikuchi-Fujimoto Lymphadenitis
236(5)
9 Immunohistochemistry
241(36)
Introduction
242(1)
Key Features Related to Technical Points in Immunohistochemistry
242(1)
List of Common Antibodies in Lymphoma Immunohistochemistry
243(2)
Near Miss
245(25)
CD20-Negative Follicular Lymphoma
245(9)
Incidental Mantle Cell Lymphoma in Reactive Looking Node
254(4)
Peripheral T-cell Lymphoma With Hodgkin-Like Cells of B-Cell Derivation
258(6)
Stains Related to Microorganisms
264(2)
Extracavitary Primary Effusion Lymphoma
266(4)
Exercise in Interpretation, Sample Write-Ups in One Single Case, and Best Practices in Write-Ups
270(7)
Self-Assessment Questions 277(12)
Self-Assessment Answers 289(8)
Index 297