This comprehensive book addresses all elements of the autonomic nervous system (ANS) and sleep interaction, as well as ANS alterations in sleep and how these impact primary and comorbid sleep dysfunction. It meets the market need for a comprehensive text that deals with ANS changes in sleep and how these impact various neurological, medical, and primary sleep disorders.
Organized into three parts, the book begins with a review of the foundational bodily systems that participate in coordination of ANS activity with other homeostatic responses such as respiration, cardiovascular reflexes, and responses to stress. Part two then examines methods of laboratory evaluation and the why, when, how of interpreting heart rate variability in sleep. To conclude, the final section of the book broadly covers the many clinical aspects of ANS, including insomnia, restless leg syndrome, sleep apnea, sleep related epilepsy, and acute autonomic neuropathy.
Autonomic Nervous System and Sleep enhances the reader's understanding of the pathophysiology of various disorders, and explains how to apply this profound understanding is important to new lines of therapy to improve morbidity.
Chapter
1. Introduction.- Part I: BASICS.-Chapter
2. Central Autonomic
Network.- Chapter
3. Functional Neuroanatomy of the Peripheral Autonomic
Nervous System.
Chapter
4. Functional Neuroanatomy and Mechanism of
Sleep.-Chapter
5. Physiological Changes in the Autonomic Nervous System
during Sleep.- Chapter
6. Brain-Heart Interaction: Cardiovascular Reflexes.-
Chapter
7. Sleep and Circadian Regulation of the Autonomic Nervous System.-
Chapter
8. Nocturnal Arousal Phenomenon and the Autonomic Nervous System.-
PART II LABORATORY EVALUATION.
Chapter
9. Methods of Laboratory Evaluation
of the Autonomic Nervous System in Wakefulness and Sleep.
Chapter
10.
Interpreting Heart Rate Variability in Sleep: Why, When, How?.
Chapter
11.
Laboratory Evaluation of Sleep Disorders: PSG, MSLT, MWT, and Actigraphy.-
PART III CLINICAL ASPECTS.-Chapter
12. An Approach to a Patient with
Suspected Autonomic Failure and Sleep Dysfunction.
Chapter
13. Obstructive
Sleep Apnea in Adults and theAutonomic Nervous System.
Chapter
14. Primary
Insomnia and Dysautonomia.
Chapter 15. Restless Leg Syndrome, Periodic Limb
Movements, ad Dysautonomia.
Chapter 16. NREM-Related Parasomnias and
Dysautonomia.
Chapter
17. Narcolepsy, Idiopathic Hypersomnia, and
Dysautonomia.
Chapter
18. Fatal Familial Insomnia.
Chapter 19.Sleep-Related
Epilepsy, Dysautonomia, and Sudden Nocturnal Death.
Chapter 20. The Postural
Tachycardia Syndrome (PoTS) .
Chapter
21. Congenital Central Hypoventilation
Syndrome.
Chapter
22. Autonomic Dysfunction in Parasomnias of REM Sleep.-
Chapter
23. Multiple System Atrophy.
Chapter
24. Pure Autonomic Failure.-
Chapter
25. Acute Autonomic Neuropathy.
Chapter
26. Familial Dysautonomia.-
Chapter
27. Diabetic Autonomic Neuropathy.
Chapter
28. Spinal Cord Lesion
and Dysautonomia.
Chapter
29. Dysautonomia and Sleep Dysfunction in
Pediatric Practice.
Chapter
30. Autonomic Regulation of Sleep-Related
Gastrointestinal Function.
Sudhansu Chokroverty, MDHackensack Meridian HealthNeuroscience Institute at JFKJFK University Medical CenterSeton Hall University & Hackensack Meridian School of Medicine at Seton HallRutgers Robert Wood Johnson Medical SchoolNew Jersey, USA Pietro Cortelli, MD, PhDIRCCS Istituto di Scienze NeurologicheDepartment of BiomedicalNeuroMotor Sciences University of BolognaBologna, Italy