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Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle [Hardback]

Edited by (Psychologist, Universidad Anįhuac Mayab, Mexico)
  • Formāts: Hardback, 220 pages, height x width: 229x152 mm, weight: 500 g
  • Izdošanas datums: 27-Mar-2019
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0128164301
  • ISBN-13: 9780128164303
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  • Cena: 156,15 €
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Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake CyclePalielināt
  • Formāts: Hardback, 220 pages, height x width: 229x152 mm, weight: 500 g
  • Izdošanas datums: 27-Mar-2019
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0128164301
  • ISBN-13: 9780128164303
Citas grāmatas par šo tēmu:
Permanent link: https://www.kriso.lv/db/9780128164303.html
Keywords:

The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to examine sleep, and examines the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in molecular mechanisms underlying sleep, and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science – why we sleep and why we cannot survive without it.

  • Reviews the neurobiological and cellular mechanisms of the sleep-wake cycle
  • Provides the implications of sleep in health and disease
  • Contrasts different techniques to study molecular mechanisms
  • Contains case studies to better illustrate points
  • Covers sleep disturbance and health problems involved in sleep
  • Includes chapters on the ontogeny of sleep, along with multiple mechanisms for sleep generation
List of Contributors
ix
Introduction xiii
Ritchie E. Brown
1 The Sleep---Wake Cycle: An Overview
1(16)
Timothy Roehrs
Thomas Roth
1.1 Introduction
2(1)
1.2 Electrophysiology of Sleep: Polysomnography
3(3)
1.3 Physiological and Cognitive Function During Sleep
6(2)
1.4 Regulation of Sleep and Wake
8(3)
1.5 Neurobiological Controls of Wake and Sleep
11(1)
1.6 Factors Influencing Sleep
12(2)
1.7 Summary
14(1)
References
15(1)
Further Reading
16(1)
2 Electrophysiological Correlates of the Sleep---Wake Cycle
17(10)
Michael D. Oliver
Subimal Datta
2.1 Overview of Sleep and the Sleep---Wake Cycle
17(2)
2.2 Stages of Sleep
19(2)
2.3 Electrophysiological Correlates
21(2)
2.4 Summary
23(1)
References
24(3)
3 Physiological Mechanisms for the Control of Waking
27(18)
Edgar Garcia-Rill
3.1 Introduction
28(1)
3.2 Waking Up and Staying Awake
29(1)
3.3 Reticular Activating System Gamma Activity
30(4)
3.4 Bottom-Up Gamma
34(1)
3.5 Locomotor Control
35(3)
3.6 Future Directions
38(1)
Acknowledgments
39(1)
References
39(6)
4 Neurochemistry and Pharmacology of Sleep
45(40)
Pablo Torterolo
Jaime M. Monti
Giancarlo Vanini
Abbreviations
46(1)
4.1 Introduction
47(1)
4.2 Sleep and Wakefulness
47(1)
4.3 Most Functions Are Modified During Sleep
48(2)
4.4 Synopsis of Waking and Sleep Mechanisms
50(2)
4.5 Neuronal Models of Sleep and Wakefulness
52(1)
4.6 Wakefulness-Promoting Neuronal Networks and Neurotransmitters
52(8)
4.7 Neural Systems That Generate NREM Sleep
60(2)
4.8 Neural Systems That Promote the Generation of REM Sleep
62(3)
4.9 The Melanin-Concentrating Hormone: A NREM and REM Sleep Promoting System
65(1)
4.10 Other Substances That Participate in the Control of Wakefulness and Sleep
65(3)
4.11 Pharmacological Approaches in Sleep Pathology
68(3)
4.12 Conclusions
71(1)
Acknowledgments
71(1)
References
72(13)
5 The Role of Neuroglobin in Brain Function and Sleep-Wake Cycle
85(18)
Oscar Ramirez-Plascencia
Mario Eduardo Acosta-Hernandez
Fabio Garcia-Garcia
5.1 Introduction
86(1)
5.2 Neuroglobin
86(1)
5.3 Neuroglobin Distribution in the Brain
87(2)
5.4 The Role of Neuroglobin in Brain Function
89(4)
5.5 Participation of the Neuroglobin in Sleep---Wake Regulation Cycle
93(2)
5.6 Conclusions
95(1)
Acknowledgments
95(1)
References
95(8)
6 Overview of Sleep Disorders
103(20)
Aljohara S. Almeneessier
Ravi Gupta
Seithikurippu R. Pandi-Perumal
Ahmed S. Bahammam
6.1 Introduction
103(16)
References
119(4)
7 Obesity and Sleep Disturbances
123(20)
Jacqueline Danisi
Julio Fernandez-Mendoza
Alexandros N. Vgontzas
Edward O. Bixler
7.1 Introduction: The Obesity Epidemic
123(2)
7.2 Etiology and Pathophysiology of Obesity
125(2)
7.3 Insufficient and Disturbed Sleep in Obesity
127(7)
7.4 The Role of Inflammation and tHe Stress System in the Association Between Obesity and Sleep Disturbances
134(3)
7.5 Conclusion
137(1)
References
138(5)
8 Sleep Disorders and Genes
143(16)
Eric Murillo-Rodri'Guez
Tetsuya Yamamoto
Andre Barciela Veras
Nuno Barbosa Rocha
Diogo Telles-Correira
Sergio Machado
Chogo Monteiro
Henning Budde
Pablo Torterolo
8.1 Introduction
144(1)
8.2 The Sleep-Wake Cycle: An Overview
145(3)
8.3 Basis of Gene Expression
148(1)
8.4 Gene Expression in Pathological Conditions
149(1)
8.5 Sleep Disorders Linked to Gene Expression
149(3)
8.6 Could We Edit Genes Related to Sleep Disorders? The Case ofCRISPR~Cas9
152(1)
8.7 Conclusions
152(1)
Acknowledgments
153(1)
References
154(4)
Further Reading
158(1)
9 Alcoholism and Sleep
159(34)
Rishi Sharma
Pradeep Sahota
Mahesh M. Thakkar
9.1 Introduction
160(1)
9.2 Sleep-Wakefulness
161(4)
9.3 Alcohol and Sleep
165(18)
9.4 Summary
183(1)
Acknowledgments
183(1)
References
184(9)
Index 193
Dr. Murillo-Rodrķguez is a Psychologist and PhD in Biomedical Sciences, having completed his post-doctoral training at Harvard Medical School. He has served as editor of multiple journals such as The International Journal of Neuropsychopharmacology and PLoS ONE, among many others. He is a member of several scientific societies, including the Society for Neuroscience. He has received academic awards such as the Young Investigator Award from the World Federation of Sleep Research and Sleep Research Societies Society, and is a member of the National System of Researchers (Level 2) of the National Council of Science and Technology (México). He is also the author of The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy (Elsevier, May 2017).