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Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation [Hardback]

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(Professor, Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA), (Associate Professor and Undergraduate Program Director, Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA)
  • Formāts: Hardback, 410 pages, height x width: 235x191 mm, weight: 870 g
  • Sērija : Biomedical Engineering
  • Izdošanas datums: 02-Nov-2011
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0123813832
  • ISBN-13: 9780123813831
Citas grāmatas par šo tēmu:
Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and MicrocirculationPalielināt
  • Formāts: Hardback, 410 pages, height x width: 235x191 mm, weight: 870 g
  • Sērija : Biomedical Engineering
  • Izdošanas datums: 02-Nov-2011
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0123813832
  • ISBN-13: 9780123813831
Citas grāmatas par šo tēmu:
Permanent link: https://www.kriso.lv/db/9780123813831.html
Keywords:

Both broad and deep in coverage, Rubenstein shows that fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement and renal transport. Each section initiates discussion with governing equations, derives the state equations and then shows examples of their usage. Clinical applications, extensive worked examples, and numerous end of chapter problems clearly show the applications of fluid mechanics to biomedical engineering situations. A section on experimental techniques provides a springboard for future research efforts in the subject area.

  • Uses language and math that is appropriate and conducive for undergraduate learning, containing many worked examples and end of chapter problems
  • All engineering concepts and equations are developed within a biological context
  • Covers topics in the traditional biofluids curriculum, as well as addressing other systems in the body that can be described by biofluid mechanics principles, such as air flow through the lungs, joint lubrication, intraocular fluid movement, and renal transport
  • Clinical applications are discussed throughout the book, providing practical applications for the concepts discussed.


Both broad and deep in coverage, Rubenstein shows that fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement and renal transport. Each section initiates discussion with governing equations, derives the state equations and then shows examples of their usage. Clinical applications, extensive worked examples, and numerous end of chapter problems clearly show the applications of fluid mechanics to biomedical engineering situations. A section on experimental techniques provides a springboard for future research efforts in the subject area.

  • Uses language and math that is appropriate and conducive for undergraduate learning, containing many worked examples and end of chapter problems
  • All engineering concepts and equations are developed within a biological context
  • Covers topics in the traditional biofluids curriculum, as well as addressing other systems in the body that can be described by biofluid mechanics principles, such as air flow through the lungs, joint lubrication, intraocular fluid movement, and renal transport
  • Clinical applications are discussed throughout the book, providing practical applications for the concepts discussed.
Preface ix
I FLUID MECHANICS BASICS
1 Introduction
1.1 Note to Student about the Textbook
3(1)
1.2 Biomedical Engineering
4(1)
1.3 Scope of Fluid Mechanics
5(1)
1.4 Scope of Biofluid Mechanics
6(2)
1.5 Dimensions and Units
8(3)
End of
Chapter Summary
9(2)
2 Fundamentals of fluid Mechanics
2.1 Fluid Mechanics Introduction
11(3)
2.2 Fundamental Fluid Mechanics Equation
14(4)
2.3 Analysis Methods
18(3)
2.4 Fluid as a Continuum
21(3)
2.5 Elemental Stress and Pressure
24(4)
2.6 Kinematics: Velocity, Acceleration, Rotation, and Deformation
28(8)
2.7 Viscosity
36(2)
2.8 Fluid Motions
38(2)
2.9 Two-Phase Flow
40(1)
2.10 Changes in the Fundamental Relationships on the Microscale
41(1)
2.11 Fluid Structure Interaction
42(7)
End of
Chapter summary
43(1)
Homework Problems
44(4)
References
48(1)
3 Conservation Laws
3.1 Fluid Statics Equation
49(9)
3.2 Buoyancy
58(2)
3.3 Conservation of Mass
60(8)
3.4 Conservation of Momentum
68(4)
3.5 Momentum Equation with Acceleration
72(5)
3.6 The First and Second Laws of Thermodynamics
77(5)
3.7 The Navier-Stokes Equations
82(7)
3.8 Bernoulli Equation
89(14)
End of
Chapter Summary
93(2)
Homework Problems
95(5)
Reference
100(3)
II MACROCIRCULATION
4 The Heart
4.1 Cardiac Physiology
103(31)
4.2 Cardiac Conduction System/ Electrocardiogram
109(3)
4.3 The Cardiac Cycle
112(3)
4.4 Heart Motion
115(4)
4.5 Heart Valve Function
119(4)
4.6 Disease Conditions
123(11)
4.6.1 Coronary Artery Disease
123(2)
4.6.2 Myocardial Infarction
125(2)
4.6.3 Heart Valve Diseases
127(1)
End of
Chapter Summary
127(2)
Homework Problems
129(2)
References
131(3)
5 Blood Flow in Arteries and Veins
5.1 Arterial System Physiology
134(3)
5.2 Venous System Physiology
137(2)
5.3 Blood Cells and Plasma
139(5)
5.4 Blood Rheology
144(3)
5.5 Pressure, Flow, and Resistance: Arterial System
147(4)
5.6 Pressure, Flow, and Resistance: Venous System
151(2)
5.7 Wave Propagation in Arterial Circulation
153(4)
5.8 Flow Separation at Bifurcations and at Walls
157(5)
5.9 Flow through Tapering and Curved Channels
162(4)
5.10 Pulsatile Flow and Turbulence
166(2)
5.11 Disease Conditions
168(14)
5.11.1 Arteriosclerosis/Stroke/High Blood Pressure
168(2)
5.11.2 Platelet Activation/ Thromboembolism
170(1)
5.11.3 Aneurysm
170(1)
End of
Chapter Summary
171(4)
Homework Problems
175(1)
References
176(6)
III MICROCIRCULATION
6 Microvascular Beds
6.1 Microcirculation Physiology
182(3)
6.2 Endothelial Cell and Smooth Muscle Cell Physiology
185(2)
6.3 Local Control of Blood Flow
187(2)
6.4 Pressure Distribution Throughout the Microvascular Beds
189(2)
6.5 Velocity Distribution Throughout the Microvascular Beds
191(5)
6.6 Interstitial Space Pressure and Velocity
196(2)
6.7 Hematocrit/Fahraeus-Lindquist Effect/ Fahraeus Effect
198(3)
6.8 Plug Flow in Capillaries
201(3)
6.9 Characteristics of Two-Phase Flow
204(1)
6.10 Interactions Between Cells and the Vessel Wall
205(3)
6.11 Disease Conditions
208(10)
6.11.1 Shock/Tissue Necrosis
208(1)
6.11.2 Edema
208(1)
End of
Chapter Summary
209(3)
Homework Problems
212(2)
References
214(4)
7 Mass Transport and Heat Transfer in the Microcirculation
7.1 Gas Diffusion
218(8)
7.2 Glucose Transport
226(1)
7.3 Vascular Permeability
227(3)
7.4 Energy Considerations
230(5)
7.5 Transport through Porous Media
235(1)
7.6 Microcirculatory Heat Transfer
236(5)
7.7 Cell Transfer During Inflammation/White Blood Cell Rolling and Sticking
241(8)
End of
Chapter Summary
242(4)
Homework Problems
246(1)
References
247(2)
8 The Lymphatic System
8.1 Lymphatic Physiology
249(4)
8.2 Lymph Formation
253(1)
8.3 Flow through the Lymphatic System
254(3)
8.4 Disease Conditions
257(8)
8.4.1 Cancer Metastasis via the Lymphatic System
257(1)
8.4.2 Lymphedema
258(1)
End of
Chapter Summary
259(1)
Homework Problems
260(1)
References
261(4)
IV OTHER BIOLOGICAL FLOWS WITHIN THE BODY
9 Flow in the Lungs
9.1 Lung Physiology
265(5)
9.2 Elasticity of the Lung Blood Vessels and Alveoli
270(2)
9.3 Pressure-Volume Relationship for Air Flow in the Lungs
272(2)
9.4 Oxygen/Carbon Dioxide Diffusion
274(4)
9.5 Oxygen/Carbon Dioxide Transport in the Blood
278(2)
9.6 Compressible Fluid Flow
280(2)
9.7 Disease Conditions
282(7)
9.7.1 Emphysema
282(1)
9.7.2 Tuberculosis
283(1)
End of
Chapter Summary
284(2)
Homework Problems
286(1)
References
287(2)
10 Intraocular Fluid Flow
10.1 Eye Physiology
289(3)
10.2 Aqueous Humor Formation
292(1)
10.3 Aquaporins
293(1)
10.4 Flow of Aqueous Humor
294(2)
10.5 Intraocular Pressure
296(2)
10.6 Disease Conditions
298(7)
10.6.1 Glaucoma
298(1)
10.6.2 Cataracts
299(1)
End of
Chapter Summary
300(1)
Homework Problems
301(1)
References
302(3)
11 Lubrication of Joints
11.1 Skeletal Physiology
305(6)
11.2 Formation of Synovial Fluid
311(1)
11.3 Synovial Fluid Flow
312(2)
11.4 Mechanical Forces within Joints
314(5)
11.5 Disease Conditions
319(6)
11.5.1 Synovitis
319(1)
End of
Chapter Summary
320(1)
Homework Problems
321(2)
References
323(2)
12 Flow Through the Kidney
12.1 Kidney Physiology
325(4)
12.2 Glomerular Filtration
329(2)
12.3 Tubule Reabsorption/Secretion
331(3)
12.4 Sodium Balance/Water Balance
334(2)
12.5 Compartmental Analysts for Urine Formation
336(2)
12.6 Extracorporeal Flows: Dialysis
338(3)
12.7 Disease Conditions
341(8)
12.7.1 Renal Calculi
341(1)
End of
Chapter Summary
342(1)
Homework Problems
343(2)
References
345(4)
V MODELING AND EXPERIMENTAL TECHNIQUES
13 In Silico Biofluid Mechanics
13.1 Computational Fluid Dynamics
349(10)
13.2 Fluid Structure Interaction Modeling
359(3)
13.3 Buckingham Pi Theorem and Dynamic Similarity
362(13)
End of
Chapter Summary
369(2)
Homework Problems
371(1)
References
372(3)
14 In vitro Biofluid Mechanics
14.1 Particle Imaging Velocimetry
375(2)
14.2 Laser Doppler Velocimetry
377(2)
14.3 Flow Chambers: Parallel Plate/Cone-and-Plate Viscometry
379(6)
End of
Chapter Summary
381(1)
Homework Problems
381(1)
References
382(3)
15 In vivo Biofluid Mechanics
15.1 Live Animal Preparations
385(2)
15.2 Doppler Ultrasound
387(3)
15.3 Phase Contrast Magnetic Resonance Imaging
390(1)
15.4 Review of Other Techniques
391(4)
End of
Chapter Summary
392(1)
Homework Problems
393(1)
References
393(2)
Further Readings Section 395(2)
Index 397
Dr. Yin conducts research into coronary artery disease, specifically how altered blood flow and stress distribution affect platelet and endothelial cell behavior and lead to cardiovascular disease initiation. The focus of Dr. Frames research is in integrating signal transduction events with physical properties of blood flow at the microvascular level, with the long term research goal of understanding the two phase question of how solute distribution and transport are coupled in the microcirculation.