Atjaunināt sīkdatņu piekrišanu

E-grāmata: Biomarkers in Toxicology

Edited by (Professor and Head, Toxicology Department, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA)
  • Formāts: PDF+DRM
  • Izdošanas datums: 25-Jan-2014
  • Izdevniecība: Academic Press Inc
  • Valoda: eng
  • ISBN-13: 9780124046498
Citas grāmatas par šo tēmu:
  • Formāts - PDF+DRM
  • Cena: 184,40 €*
  • * ši ir gala cena, t.i., netiek piemērotas nekādas papildus atlaides
  • Ielikt grozā
  • Pievienot vēlmju sarakstam
  • Šī e-grāmata paredzēta tikai personīgai lietošanai. E-grāmatas nav iespējams atgriezt un nauda par iegādātajām e-grāmatām netiek atmaksāta.
  • Formāts: PDF+DRM
  • Izdošanas datums: 25-Jan-2014
  • Izdevniecība: Academic Press Inc
  • Valoda: eng
  • ISBN-13: 9780124046498
Citas grāmatas par šo tēmu:

DRM restrictions

  • Kopēšana (kopēt/ievietot):

    nav atļauts

  • Drukāšana:

    nav atļauts

  • Lietošana:

    Digitālo tiesību pārvaldība (Digital Rights Management (DRM))
    Izdevējs ir piegādājis šo grāmatu šifrētā veidā, kas nozīmē, ka jums ir jāinstalē bezmaksas programmatūra, lai to atbloķētu un lasītu. Lai lasītu šo e-grāmatu, jums ir jāizveido Adobe ID. Vairāk informācijas šeit. E-grāmatu var lasīt un lejupielādēt līdz 6 ierīcēm (vienam lietotājam ar vienu un to pašu Adobe ID).

    Nepieciešamā programmatūra
    Lai lasītu šo e-grāmatu mobilajā ierīcē (tālrunī vai planšetdatorā), jums būs jāinstalē šī bezmaksas lietotne: PocketBook Reader (iOS / Android)

    Lai lejupielādētu un lasītu šo e-grāmatu datorā vai Mac datorā, jums ir nepieciešamid Adobe Digital Editions (šī ir bezmaksas lietotne, kas īpaši izstrādāta e-grāmatām. Tā nav tas pats, kas Adobe Reader, kas, iespējams, jau ir jūsu datorā.)

    Jūs nevarat lasīt šo e-grāmatu, izmantojot Amazon Kindle.

General introductory chapters discuss modeling with rodents, minipigs, nonhuman primates, zebrafish, and other animals, as well as alternative animal toxicity testing. Subsequent chapters address biomarkers as indicators of exposure, effect, and susceptibility. Coverage encompasses systems toxicity (e.g. central nervous, cardiovascular, and respiratory systems); agents (e.g. insecticides metals, chemical and biological warfare agents); pharmaceuticals and nutraceuticals; radiation, nanoparticles, and carcinogenesis; and special topics (e.g. Alzheimer's, Parkinson's). The concluding chapters discuss applications. Annotation ©2014 Ringgold, Inc., Portland, OR (protoview.com)

Biomarkers in Toxicology is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This book includes both vertebrate and non-vertebrate species models for toxicological testing and development of biomarkers. Divided into several key sections, this reference volume contains chapters devoted to topics in molecular-cellular toxicology, as well as a look at the latest cutting-edge technologies used to detect biomarkers of exposure and effects. Each chapter also contains several references to the current literature and important resources for further reading. Given this comprehensive treatment, Biomarkers in Toxicology is an essential reference for all those interested in biomarkers across several scientific and biomedical fields.

  • Written by international experts who have evaluated the expansive literature to provide you with one resource covering all aspects of toxicology biomarkers
  • Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure and effect of chemicals of different classes
  • Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation and much more

Recenzijas

"...thoroughly conveys the very important role that biomarkers play in biological research and other applicationsprovides an indepth reference resource for those in the field of toxicology and chemical safety assessment."--Lab Animal

"...an important text for every toxicologist because the scope of the volume is greater than simply identifying indicators of adverse consequences of toxicants...will become a standard text and reference for every toxicologist." -International Journal of Toxicology

"This is a thorough book, covering animal models, organ systems, and specific xenobiotic classes in biomarker research. Animal models and mechanisms of toxicity are particularly well coveredThis is the first book of its kind, and it is a fantastic introduction and reference for anyone interested in biomarkers of toxicity." Rating: 3 Stars --Doody.com, June 6, 2014

"The book presents an excellent comprehensive discussion of biomarkers in various specialized areas of toxicology. These include toxicity testing models, biomarkers in biological systems and special physiological states such as certain disease conditions, specific agents as biomarkers, and biomarkers of special areas of interest such as petroleum products, radiation, nanoparticles and carcinogenesis. It strengthens the scientific information with discussions in biomarker applications in toxicology such as in biomonitoring, evaluation of pharmaceuticals and susceptibility, indicators of toxicity, computational toxicology and risk assessment. It is unique in the broad coverage in the overall areas and in the in-depth knowledge in each area. The discussion of biomarkers in biological or organ systems is particularly useful for an understanding of some issues relating to key toxicity endpoints for the nervous system, cardiovascular system, respiratory system, ocular system, gastrointestinal system, skeletal system, immune system, placenta, blood and bone marrow, kidney, liver and pancreas. It is an outstanding reference source for those interested in biomarkers in scientific and biomedical fields, toxicology and risk assessment." -Anna M. Fan, PhD, DABT, California EPA, Office of Environmental Health Hazard Assessment, Oakland, CA

"Natural and man-made toxins (pesticides, manufacturing chemicals, natural toxins, etc.) are important elements of the world where we now live. This book, Biomarkers in Toxicology provides an extensive and broad review of current markers for toxicological exposure provided by contributing experts from across the world and across multiple disciplines. This rapidly emerging and important field has relevance in human and animal health including risks from environmental, accidental or intentional exposures to natural toxins and anthropogenic compounds. This comprehensive review is a valuable and important resource for scientists, regulators, diagnosticians, epidemiologists, clinicians, veterinarians and others interested in toxicology. This is an excellent overview of the current state of knowledge of Biomarkers in toxicology and will surely provide the basis for future editions as this rapidly changing field progresses." -Kip E. Panter, PhD, USDA- Agricultural Research Service, Poisonous Plant Research Laboratory, Logan, UT

Papildus informācija

The single most comprehensive reference devoted to all aspects of biomarkers in toxicology, bringing together a unique and focused evaluation of the latest research and technologies in this area
Foreword xi
List of Contributors
xiii
Part I General
1 Introduction
3(4)
Ramesh C. Gupta
2 Rodents model for toxicity testing and biomarkers
7(64)
Shayne C. Gad
3 Minipig models for toxicity testing and biomarkers
71(22)
Niels-Christian Ganderup
4 Nonhuman primates in preclinical research
93(10)
Adam D. Aulbach
Daniel J. Patrick
Ali Faqi
5 Biomarkers of toxicity in zebrafish
103(10)
Stephanie Padilla
6 Caenorhabditis elegans as a model for biomarkers of diseases and toxicities
113(16)
Vanessa A. Fitsanakis
Rekek Negga
Holly E. Hatfield
7 Alternative animal toxicity testing and biomarkers
129(20)
Gopala Krishna
Saryu Goel
Kavya A. Krishna
8 Toxicokinetic-toxicodynamic modeling
149(8)
Ronette Gehring
Deon van der Merwe
Part II Systems Toxicity Biomarkers
9 Central nervous system toxicity biomarkers
157(12)
Lucio G. Costa
Claudia Pellacani
10 Peripheral nervous system toxicity biomarkers
169(30)
T.V. Damodaran
11 Cardiovascular toxicity biomarkers
199(18)
Csaba K. Zoltani
12 Respiratory toxicity biomarkers
217(24)
Urmila P. Kodavanti
13 Hepatic toxicity biomarkers
241(20)
Xi Yang
Laura K. Schnackenberg
Qiang Shi
William F. Salminen
14 Conventional and emerging renal biomarkers
261(8)
Sue M. Ford
15 Gastrointestinal toxicity biomarkers
269(10)
Aryamitra Banerjee
16 Biomarkers of acute and chronic pancreatitis
279(12)
Bhupendra S. Kaphalia
17 Skeletal muscle toxicity biomarkers
291(18)
Ramesh C. Gupta
Michelle A. Lasher
Robin B. Doss
Dejan Milatovic
18 Dermal toxicity biomarkers
309(8)
Diane E. Heck
Laurie B. Joseph
Hong Duck Kim
19 Ocular biomarkers in diseases and toxicities
317(8)
George A. Kontadakis
Argyro Plaka
Domniki Fragou
George D. Kymionis
Aristides M. Tsatsakis
20 Biomarkers of toxicity in human placenta
325(36)
Kirsi Vahakangas
Jarkko Loikkanen
Heidi Sahlman
Vesa Karttunen
Jenni Repo
Elina Sieppi
Maria Kummu
Pasi Huuskonen
Kirsi Myohanen
Markus Storvik
Markku Pasanen
Paivi Myllynen
Olavi Pelkonen
21 Blood and bone marrow toxicity biomarkers
361(12)
Sharon Gwaltney-Brant
22 Immunotoxicity biomarkers
373(16)
Sharon Gwaltney-Brant
Part III Agents Toxicity Biomarkers
23 Insecticides
389(20)
Ramesh C. Gupta
Dejan Milatovic
24 Herbicides and fungicides
409(24)
P.K. Gupta
25 Polychlorinated biphenyls, polybrominated biphenyls, and brominated flame retardants
433(18)
Prasada Rao S. Kodavanti
Bommanna G. Loganathan
26 Polycyclic aromatic hydrocarbons
451(8)
Leah D. Banks
Kelly L. Harris
Jane A. Mantey
Darryl B. Hood
Anthony E. Archibong
Aramandla Ramesh
27 Bisphenol A
459(16)
Patrick Allard
28 Melamine
475(10)
Karyn Bischoff
29 Metals
485(36)
Swaran J.S. Flora
30 Chemical and biological warfare agents
521(18)
D. Thavaselvam
Swaran S. Flora
31 Freshwater cyanotoxins
539(10)
Deon van der Merwe
32 Mycotoxins
549(14)
R.W. Coppock
Margitta M. Dziwenka
33 Poisonous plants: biomarkers for diagnosis
563(30)
Kip E. Panter
Kevin D. Welch
Dale R. Gardner
Part IV Pharmaceuticals and Nutraceuticals Biomarkers
34 Biomarkers of drug toxicity
593(16)
Arturo Anadon
Victor Castellano
Maria Rosa
Martinez-Larranaga
35 Biomarkers of toxicity for dietary ingredients contained in dietary supplements
609(20)
Corey J. Hilmas
Daniel S. Fabricant
36 Nutriphenomics in rodent models: Impact of dietary choices on toxicological biomarkers
629(18)
Michael A. Pellizzon
Matthew R. Ricci
Part V Biomarkers of Petroleum Products and Mixtures Toxicity
37 Biomarkers of petroleum products toxicity
647(8)
R.W. Coppock
Margitta M. Dziwenka
38 Biomarkers of chemical mixture toxicity
655(18)
Antonio F. Hernandez
Fernando Gil
Aristides M. Tsatsakis
Part VI Biomarkers of Radiation, Nanoparticles, and Carcinogenesis
39 Biomarkers of radiation injury and response
673(16)
Kausik Ray
Kathryn Hudak
Deborah Citrin
Melissa Stick
40 Biomarker analysis for nanotoxicology
689(8)
Evangelia Hondroulis
Jairo Nelson
Chen-zhong Li
41 Engineered nanomaterials: Biomarkers of exposure and effect
697(20)
Enrico Bergamaschi
Mary Gulumian
Jun Kanno
Kai Savolainen
42 Epigenetic biomarkers in toxicology
717(12)
Angela Aliberti
Frank A. Barile
43 Genotoxicity biomarkers: Molecular basis of genetic variability and susceptibility
729(14)
S. Beedanagari
S. V. Vulimiri
S. Bhatia
B. Mahadevan
44 Risk factors as biomarkers of susceptibility in breast cancer
743(16)
Casey E. Reed
Suzanne E. Fenton
45 Pancreatic and ovarian cancer biomarkers
759(12)
Brian M. Nolen
Anna E. Lokshin
46 Prostate cancer biomarkers
771(14)
Yi Lu
Chikezie Madu
47 Biomonitoring exposures to carcinogens
785(16)
Sofia Pavanello
Marcello Lotti
Part VII Special Topics
48 Biomarkers of Alzheimer's disease
801(16)
Jason Pitt
49 Biomarkers of Parkinson's disease
817(16)
Huajun Jin
Arthi Kanthasamy
Vellareddy Anantharam
Anumantha G. Kanthasamy
50 Cytoskeletal disruption as a biomarker of developmental neurotoxicity
833(14)
Alan J. Hargreaves
Magdalini Sachana
John Flaskos
51 Biomarkers of mitochondrial dysfunction and toxicity
847(16)
Carlos M. Palmeira
Filipe V. Duarte
Joao S. Teodoro
Ana T. Varela
Anabela P. Rolo
52 Biomarkers of oxidative/nitrosative stress and neurotoxicity
863(20)
Dejan Milatovic
Snjezana Zaja-Milatovic
Ramesh C. Gupta
53 Citrulline: Pharmacological perspectives and role as a biomarker in diseases and toxicities
883(24)
Shilpa N. Kaore
Navinchandra M. Kaore
54 Pathological biomarkers in toxicology
907(16)
Meliton N. Novilla
Vincent P. Meador
Stewart B. Jacobson
Part VIII Applications of Biomarkers in Toxicology
55 Biomarkers in drug safety evaluation
923(24)
Arturo Anadon
Victor Castellano
Maria Rosa Martinez-Larranaga
56 Membrane transporters and transporter substrates as biomarkers for drug pharmacokinetics, pharmacodynamics, and toxicity/adverse events
947(18)
Beata Toth
Peter Krajcsi
Remi Magnan
57 Biomarkers in biomonitoring of xenobiotics
965(10)
Miguel A. Sogorb
Jorge Estevez
Eugenio Vilanova
58 Biomarkers of susceptibility
975(8)
James J. Chen
Wei-Jiun Lin
Tzu-Pin Lu
59 Biomarkers for drugs of abuse and neuropsychiatric disorders: Models and mechanisms
983(20)
Pushpinder Kaur Multani
Nitin Saini
Ravneet Kaur
Praveen Sharma
60 MicroRNA expression as an indicator of tissue toxicity
1003(16)
Andrew D. Penman
Greer E. Kaufman
Kellye K. Daniels
61 Percellome toxicogenomics project as a source of biomarkers of chemical toxicity
1019(14)
Jun Kanno
62 Transcriptomic biomarkers in safety and risk assessment of chemicals
1033(6)
David T. Szabo
63 Biomarkers in computational toxicology
1039(18)
Yu-Mei Tan
Daniel T. Chang
Martin Phillips
Stephen Edwards
Christopher M. Grulke
Michael-Rock Goldsmith
Jon Sobus
Rory Conolly
Rogelio Tornero-Velez
Curtis C. Dary
64 Biomarkers in toxicology, risk assessment, and environmental chemical regulations
1057(24)
Anna M. Fan
Index 1081
Dr. Ramesh C. Gupta, Professor & Head of Toxicology Department at Murray State university, is engaged in experimental brain research in relation to Alzheimers disease (AD) and pesticide toxicity. He has delivered lectures in Australia, Italy, Japan, Germany, France, Switzerland, Spain, Czech Republic, China, South Korea, and Sweden. He served the panels of NIH, CDC, NIOSH, and NAS. He has >350 publications to his credit, including seven major books with Elsevier: (1) Toxicology of Organophosphate and Carbamate Compounds, (2) Veterinary Toxicology: Basic and Clinical Principles, (3) Handbook of Toxicology of Chemical Warfare Agents, (4) Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology, (5) Reproductive and Developmental Toxicology, (6) Biomarkers in Toxicology and (7) Neutraceuticals. He is recipient of Murray State University's distinguished researcher award of the year-2006. He is a diplomate of American Board of Toxicology, and fellow of American College of Toxicology, American College of Nutrition, and Academy of Toxicological Sciences.