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Biomedical Applications of Extracellular Vesicles [Hardback]

Series edited by , (Southern Medical University, China), (Columbia University, USA), Series edited by , (Chinese Academy of Sciences)
  • Formāts: Hardback, 208 pages, height x width x depth: 244x170x20 mm, weight: 567 g
  • Izdošanas datums: 27-Dec-2023
  • Izdevniecība: Blackwell Verlag GmbH
  • ISBN-10: 3527352120
  • ISBN-13: 9783527352128
Citas grāmatas par šo tēmu:
  • Hardback
  • Cena: 165,25 €
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  • Formāts: Hardback, 208 pages, height x width x depth: 244x170x20 mm, weight: 567 g
  • Izdošanas datums: 27-Dec-2023
  • Izdevniecība: Blackwell Verlag GmbH
  • ISBN-10: 3527352120
  • ISBN-13: 9783527352128
Citas grāmatas par šo tēmu:
Biomedical Applications of Extracellular Vesicles

Unique resource focusing on biomedical applications and clinical translation of extracellular vesicles in science and medicine

Focusing on key points to better understand extracellular vesicles (EVs) and their development, Biomedical Applications of Extracellular Vesicles describes in detail the biogenesis of EVs, the mechanism of intercellular communication, and the treatment of various diseases of EVs and the EV-based drug delivery platforms. An application-oriented resource, the work presents rapidly newer biomedical and clinical applications of natural and engineered EVs such as drug delivery, diagnosis, prognosis monitoring, immunotherapy, and more.

The first part of this book provides a basic background on EVs. Next, the book introduces the excellent therapeutic effects of EVs themselves and the underlying mechanisms, followed by how EVs from different sources were used to construct drug delivery platforms. The latest research on EVs from leading groups around the world is presented.

Sample topics covered in Biomedical Applications of Extracellular Vesicles include:

  • Biogenesis of various EVs
  • Pros and cons of the different instrumental and methodological developments for analytical strategies applied to EVs
  • EVs in treatment of major diseases, such as cancer, cardiovascular and respiratory diseases
  • Current methods of engineering EVs, and a comparison of the advantages and disadvantages of each method
  • Biomaterials, such as hydrogels, scaffolds, and microneedles, that have been developed to further enhance the therapeutic efficacy of EVs
  • Key challenges, such as quality control, scalability, and biosafety, that limit the clinical and industrial translation of EVs

Explaining in detail how extracellular vesicles are produced and engineered, along with potential applications and commercial developments of EVs in science and industry, Biomedical Applications of Extracellular Vesicles is an essential resource on the subject for chemists, cell biologists, and molecular physicists.

1 Introduction
2 Exosome biogenesis and identification
3 Biological applications of exosomes from different cell sources
4 Therapeutic potential of extracellular vesicles in treatment of disease
5 Applications of engineered extracellular vesicles
6 Current technology for extracellular vesicles production, isolation and quality control
7 Prospects and limitations of clinical application of exosomes
8 Conclusion and future perspectives
Dr. Zhenhua Li is Professor at Southern Medical University, China. He serves as an editorial board member of Extracellular Vesicle, Exploration, Materials Today Bio.

Dr. Xing-Jie Liang is Deputy Director of Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences.

Dr. Ke Cheng is a Professor of Biomedical Engineering at Columbia University.