| List of Contributors |
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xi | |
| Preface |
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xiii | |
| Chapter 1 Anatomy and physiology of major organ systems |
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1 | (34) |
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1 | (5) |
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6 | (5) |
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11 | (6) |
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17 | (4) |
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21 | (2) |
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23 | (8) |
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31 | (2) |
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33 | (2) |
| Chapter 2 Pathophysiology |
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35 | (54) |
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2.1 Pathophysiology: a definition |
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35 | (1) |
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2.2 Introduction to epidemacology |
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35 | (3) |
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2.3 Introduction to phamacology |
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38 | (6) |
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44 | (6) |
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2.5 Liver, biliary tract and pancreatic disease |
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50 | (6) |
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56 | (3) |
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2.7 Urinary tract disease |
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59 | (6) |
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2.8 Cardiovascular disease |
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65 | (11) |
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76 | (4) |
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80 | (8) |
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88 | (1) |
| Chapter 3 Clinical cell biology and genetics |
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89 | (50) |
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89 | (14) |
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103 | (13) |
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3.3 Human genetic disorders |
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116 | (20) |
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3.4 Important techniques in molecular cell biology |
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136 | (2) |
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138 | (1) |
| Chapter 4 Christopher M. Stonard and Jennifer H. Stonard |
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139 | (66) |
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Part I: Principles of cellular pathology |
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139 | (36) |
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4.1 Structure and function of normal cells, tissues and organs |
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139 | (1) |
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140 | (1) |
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4.3 Cellular responses to injury |
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141 | (2) |
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4.4 Tissue responses to injury: acute inflammation |
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143 | (6) |
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4.5 Tissue responses to injury: chronic inflammation |
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149 | (2) |
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151 | (3) |
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4.7 Hyperplasia and hypertrophy |
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154 | (1) |
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155 | (2) |
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4.9 Thrombosis and embolism |
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157 | (2) |
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4.10 Ischaemia and infarction |
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159 | (1) |
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4.11 Amyloid and amyloidosis |
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160 | (2) |
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4.12 Infections of histological importance |
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162 | (3) |
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4.13 Metaplasia, dysplasia and carcinoma in situ |
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165 | (3) |
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168 | (7) |
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Part II: Clinical application and laboratory techniques |
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175 | (28) |
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175 | (3) |
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178 | (2) |
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180 | (2) |
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4.18 Processing and embedding |
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182 | (2) |
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184 | (2) |
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4.20 Standard staining methods and procedures |
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186 | (4) |
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190 | (1) |
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4.22 Immunohistochemistry |
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191 | (5) |
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196 | (1) |
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197 | (4) |
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4.25 In situ hybridization |
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201 | (2) |
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203 | (2) |
| Chapter 5 Clinical Chemistry |
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205 | (56) |
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205 | (1) |
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Part I: Analytical methods |
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205 | (27) |
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205 | (5) |
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5.2 Analytical methods in clinical chemistry laboratories |
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210 | (21) |
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5.3 Summary: common clinical tests for sample analytes |
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231 | (1) |
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Part II: Clinical assessments |
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232 | (27) |
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5.4 Urea and electrolytes (U and Es) |
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232 | (2) |
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5.5 Metabolism and gastrointestinal markers |
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234 | (2) |
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236 | (1) |
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237 | (1) |
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5.8 Heart disease and lipid disorder tests |
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238 | (2) |
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5.9 Pancreatic function tests |
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240 | (1) |
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5.10 Bone disease assessment |
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241 | (1) |
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5.11 Endocrinological assessments |
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241 | (8) |
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5.12 Pregnancy tests and pregnancy clinical chemistry |
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249 | (2) |
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5.13 Therapeutic drug monitoring and toxicology |
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251 | (2) |
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5.14 Clinical chemistry at the extremes of age |
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253 | (1) |
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254 | (5) |
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259 | (2) |
| Chapter 6 Medical microbiology |
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261 | (50) |
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261 | (1) |
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6.1 Overview of microorganisms |
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261 | (4) |
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6.2 Laboratory investigation of infection |
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265 | (12) |
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277 | (7) |
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284 | (4) |
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6.5 Parasitology-protozoa and helminths |
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288 | (2) |
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290 | (7) |
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297 | (1) |
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6.8 Infections in the immunocompromised patient |
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298 | (1) |
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6.9 Healthcare associated infections |
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299 | (3) |
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6.10 Antimicrobial agents |
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302 | (5) |
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307 | (2) |
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309 | (1) |
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309 | (2) |
| Chapter 7 Clinical immunology |
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311 | (18) |
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Part I: The fundamentals of immunology |
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311 | (12) |
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7.1 Overview of the immune system |
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311 | (5) |
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7.2 Overview of the immune response |
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316 | (5) |
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7.3 MHC genotyping, autoimmunity and susceptibility to disease |
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321 | (1) |
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7.4 Physical age and immunocompetency |
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322 | (1) |
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Part II: Laboratory investigations and immune assessments |
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323 | (5) |
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7.5 Inflammation and chronic infection |
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323 | (1) |
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324 | (1) |
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325 | (1) |
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326 | (1) |
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326 | (2) |
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328 | (1) |
| Chapter 8 Suzanne M. Docherty |
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329 | (68) |
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8.1 Introduction and components of blood |
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329 | (3) |
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8.2 Routine laboratory blood tests |
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332 | (4) |
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336 | (1) |
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8.4 Red blood cell structure, disorders and metabolism |
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337 | (5) |
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342 | (11) |
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353 | (6) |
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8.7 Benign white blood cell disorders |
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359 | (2) |
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361 | (5) |
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8.9 Coagulation disorders |
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366 | (5) |
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8.10 Myeloproliferative disorders |
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371 | (2) |
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8.11 Haematological malignancies |
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373 | (5) |
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378 | (2) |
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380 | (10) |
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390 | (3) |
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8.15 Haemopoetic stem cell transplantation |
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393 | (2) |
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395 | (2) |
| Chapter 9 Professional practice and biomedical science |
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397 | (10) |
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9.1 What is a biomedical scientist? |
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397 | (1) |
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397 | (1) |
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9.3 Professional practice and the role of the HPC |
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398 | (1) |
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9.4 Standards of proficiency-biomedical scientists |
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399 | (1) |
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9.5 Expectations of a health professional |
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400 | (1) |
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9.6 Professional relationships |
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401 | (1) |
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9.7 The skills required for the application of practice |
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401 | (1) |
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9.8 Knowledge, understanding and skills |
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402 | (1) |
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9.9 Standards of conduct, performance and ethics |
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403 | (1) |
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403 | (1) |
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404 | (1) |
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404 | (1) |
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9.13 The professional biomedical scientist as an agent for change in the wider healthcare setting |
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405 | (2) |
| Appendix |
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407 | (6) |
| Index |
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413 | |
Biežāk uzdotie jautājumi par e-grāmatām