1 Introduction: the issues |
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1 | (11) |
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1 | (2) |
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1.2 Rewards and punishers |
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3 | (2) |
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1.3 The approaches taken to emotion and motivation |
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5 | (6) |
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1.3.1 The causes of emotion |
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5 | (2) |
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1.3.2 The importance of understanding the primate, including human, brain |
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7 | (2) |
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1.3.3 Functional neuroimaging in humans, neuronal encoding, and understanding the brain computationally |
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9 | (2) |
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1.4 Emotion, motivation, and depression: the plan of the book |
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11 | (1) |
2 The nature of emotion |
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12 | (21) |
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12 | (1) |
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12 | (2) |
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14 | (8) |
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2.4 Other theories of emotion |
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22 | (3) |
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2.4.1 The James-Lange and other bodily theories |
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22 | (1) |
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23 | (1) |
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2.4.3 Dimensional and categorical theories of emotion |
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24 | (1) |
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2.4.4 Other approaches to emotion |
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24 | (1) |
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2.5 Individual differences in emotion, personality, and emotional intelligence |
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25 | (2) |
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2.6 Cognition and emotion |
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27 | (2) |
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2.7 Emotion, motivation, reward, and mood |
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29 | (1) |
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2.8 Advantages of the approach to emotion described here (Rolls' theory of emotion) |
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30 | (3) |
3 The functions of emotion: reward, punishment, and emotion in brain design |
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33 | (17) |
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33 | (1) |
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3.2 Brain design and the functions of emotion |
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33 | (6) |
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3.2.1 Taxes, rewards, and punishers: gene-specified goals for actions, and the flexibility of actions |
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33 | (4) |
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3.2.2 Explicit systems, language, and reinforcement |
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37 | (1) |
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3.2.3 Special-purpose design by an external agent vs evolution by natural selection |
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38 | (1) |
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3.3 Selection of behaviour: cost-benefit 'analysis' of net value |
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39 | (1) |
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3.4 Further functions of emotion |
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40 | (6) |
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3.4.1 Autonomic and endocrine responses |
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40 | (1) |
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3.4.2 Flexibility of behavioural actions |
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41 | (1) |
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3.4.3 Emotional states are motivating |
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41 | (2) |
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43 | (1) |
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43 | (1) |
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3.4.6 Separate functions for each different primary reinforcer |
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44 | (1) |
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3.4.7 The mood state can influence the cognitive evaluation of moods or memories |
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44 | (1) |
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3.4.8 Facilitation of memory storage |
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45 | (1) |
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3.4.9 Emotional and mood states are persistent, and help to produce persistent motivation |
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45 | (1) |
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3.4.10 Emotions may trigger memory recall and influence cognitive processing |
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45 | (1) |
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3.5 The functions of emotion in an evolutionary, Darwinian, context |
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46 | (2) |
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3.6 The functions of motivation in an evolutionary, Darwinian, context |
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48 | (1) |
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3.7 Are all goals for action gene-specified? |
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49 | (1) |
4 The brain mechanisms underlying emotion |
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50 | (73) |
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50 | (1) |
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4.2 Overview of brain systems involved in emotion |
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50 | (5) |
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4.3 Representations of primary reinforcers, i.e. of unlearned value |
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55 | (4) |
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55 | (1) |
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55 | (1) |
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4.3.3 Pleasant and painful touch |
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56 | (2) |
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58 | (1) |
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4.4 Learning associations between stimuli and primary reinforcers: emotion-related learning |
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59 | (7) |
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4.4.1 Emotion-related learning about visual stimuli in the orbitofrontal cortex |
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59 | (3) |
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4.4.2 The visual inputs from the temporal lobe cortex to the orbitofrontal cortex and amygdala for emotion-related learning |
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62 | (4) |
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4.5 The orbitofrontal cortex and emotion |
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66 | (29) |
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4.5.1 Historical background |
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66 | (1) |
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4.5.2 Connections of the orbitofrontal cortex |
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67 | (2) |
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4.5.3 Neurophysiology and functional neuroimaging of the orbitofrontal cortex |
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69 | (20) |
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4.5.4 The human orbitofrontal cortex |
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89 | (3) |
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4.5.5 A neurophysiological and computational basis for stimulus-reinforcer association learning and reversal in the orbitofrontal cortex |
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92 | (3) |
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4.6 The amygdala and emotion |
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95 | (10) |
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4.6.1 Overview of the functions of the amygdala in emotion |
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95 | (1) |
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4.6.2 The amygdala and the associative processes involved in emotion-related learning |
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96 | (1) |
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4.6.3 Connections of the amygdala |
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96 | (2) |
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4.6.4 Effects of amygdala lesions |
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98 | (2) |
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4.6.5 Neuronal activity in the primate amygdala to reinforcing stimuli |
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100 | (2) |
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4.6.6 Responses of primate amygdala neurons to novel stimuli that are reinforcing |
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102 | (1) |
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4.6.7 Neuronal responses in the amygdala to faces |
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103 | (1) |
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4.6.8 Evidence from humans |
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103 | (2) |
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4.7 The cingulate cortex and emotion |
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105 | (7) |
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4.7.1 Introduction and overview of the anterior cingulate cortex |
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105 | (2) |
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4.7.2 Anterior cingulate cortex anatomy and connections |
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107 | (1) |
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4.7.3 Anterior cingulate cortex functional neuroimaging and neuronal activity |
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108 | (2) |
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4.7.4 Anterior cingulate cortex lesion effects |
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110 | (1) |
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4.7.5 Mid-cingulate cortex, the cingulate motor area, and action-outcome learning |
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111 | (1) |
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112 | (4) |
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4.9 Effects of emotion on cognitive processing and memory |
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116 | (2) |
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4.10 Summary of brain systems involved in emotion |
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118 | (5) |
5 Food reward value, pleasure, appetite, hunger, and over-eating |
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123 | (24) |
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123 | (1) |
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5.2 The control signals for hunger and satiety |
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124 | (5) |
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5.2.1 Reward vs satiety signals |
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124 | (1) |
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5.2.2 Sensory-specific satiety |
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124 | (5) |
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5.2.3 Conditioned appetite and satiety |
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129 | (1) |
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5.3 The brain control of eating and reward |
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129 | (11) |
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5.3.1 Brain mechanisms for taste reward value |
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129 | (6) |
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5.3.2 Convergence between taste and olfactory processing to represent flavour |
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135 | (1) |
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5.3.3 Brain mechanisms for the reward produced by the odour of food |
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136 | (1) |
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5.3.4 The responses of orbitofrontal cortex taste and olfactory neurons to the sight of food: expected value neurons |
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137 | (1) |
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5.3.5 Functions of the amygdala in feeding |
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137 | (1) |
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5.3.6 Functions of the orbitofrontal cortex in eating |
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138 | (1) |
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5.3.7 Output pathways for feeding |
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139 | (1) |
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5.4 Obesity and the reward value of food |
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140 | (7) |
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141 | (1) |
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5.4.2 Brain processing of the sensory properties and pleasantness of food |
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141 | (2) |
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143 | (1) |
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5.4.4 Sensory-specific satiety |
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143 | (1) |
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5.4.5 Fixed meal times, and the availability of food |
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143 | (1) |
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5.4.6 Food saliency, and portion size |
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143 | (1) |
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5.4.7 Energy density of food |
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144 | (1) |
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144 | (1) |
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144 | (1) |
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144 | (1) |
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144 | (1) |
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5.4.12 Cognitive factors, and attention |
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145 | (1) |
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5.4.13 Weight gain in women at midlife |
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145 | (1) |
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5.4.14 Compliance with information about risk factors for obesity |
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146 | (1) |
6 Pharmacology of emotion, reward, and addiction; the basal ganglia |
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147 | (12) |
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6.1 Overview of the pharmacology of emotion |
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147 | (1) |
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6.2 Dopamine systems in the brain |
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147 | (5) |
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6.2.1 Dopamine pharmacology |
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148 | (1) |
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148 | (1) |
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6.2.3 Self-administration of dopaminergic substances, and addiction |
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149 | (1) |
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6.2.4 Behaviours associated with the release of dopamine |
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150 | (1) |
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6.2.5 Dopamine neurons and reward prediction error |
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151 | (1) |
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152 | (4) |
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6.3.1 Overview of the basal ganglia |
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152 | (1) |
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6.3.2 Systems-level architecture of the basal ganglia |
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153 | (1) |
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6.3.3 Neuronal activity in the striatum |
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154 | (2) |
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6.4 Opiate reward systems, analgesia, and food reward |
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156 | (1) |
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6.5 Pharmacology of anxiety in relation to brain systems involved in emotion |
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156 | (1) |
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157 | (2) |
7 Sexual behaviour, reward, and brain function |
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159 | (29) |
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159 | (1) |
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7.2 Mate selection, attractiveness, and love |
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160 | (7) |
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161 | (2) |
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163 | (3) |
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7.2.3 Pair-bonding, and love |
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166 | (1) |
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7.3 Parental attachment, care, and parent-offspring conflict |
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167 | (2) |
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7.4 Sperm competition and its consequences for sexual behaviour |
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169 | (4) |
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7.5 Female cryptic choice and its consequences for sexual behaviour |
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173 | (1) |
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7.6 Concealed ovulation and concealed estrus and their consequences for sexual behaviour |
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174 | (2) |
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7.7 Sexual selection of sexual and non-sexual behaviour |
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176 | (5) |
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7.7.1 Sexual selection and natural selection |
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176 | (3) |
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7.7.2 Non-sexual characteristics may be sexually selected for courtship |
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179 | (2) |
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7.8 Neural basis of sexual behaviour |
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181 | (6) |
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7.8.1 Olfactory rewards and pheromones |
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181 | (2) |
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7.8.2 Preoptic area and hypothalamus |
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183 | (2) |
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7.8.3 Orbitofrontal cortex and related areas |
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185 | (2) |
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187 | (1) |
8 Decision-making and attractor networks |
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188 | (13) |
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8.1 Overview of decision-making |
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188 | (1) |
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8.2 Decision-making in an attractor network |
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189 | (7) |
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8.2.1 An attractor decision-making network |
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189 | (2) |
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8.2.2 The operation of a model of decision-making |
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191 | (3) |
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8.2.3 Using the model to locate reward-related decision-making attractor networks in the brain |
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194 | (2) |
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8.3 Implications and applications of this approach to decision-making |
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196 | (5) |
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8.3.1 Multiple decision-making systems in the brain |
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196 | (1) |
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8.3.2 Distributed decision-making |
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196 | (1) |
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8.3.3 Predicting a decision before the evidence is provided |
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196 | (1) |
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197 | (1) |
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197 | (1) |
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8.3.6 The evolutionary utility of probabilistic choice |
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198 | (1) |
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8.3.7 Unpredictable behaviour |
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198 | (1) |
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199 | (1) |
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199 | (1) |
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8.3.10 Decision-making between the emotional and rational systems |
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200 | (1) |
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8.3.11 Dynamical neuropsychiatry: schizophrenia, obsessive-compulsive disorder, and memory changes in normal aging |
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200 | (1) |
9 Depression |
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201 | (38) |
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201 | (6) |
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9.1.1 The economic and social cost of depression |
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201 | (1) |
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9.1.2 The triggers and causes of depression: non-reward systems |
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201 | (4) |
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9.1.3 Brain systems that underlie depression |
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205 | (2) |
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9.2 A non-reward attractor theory of depression |
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207 | (1) |
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9.3 Evidence consistent with the non-reward attractor theory of depression |
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208 | (3) |
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9.4 Advances in understanding the functions of the orbitofrontal cortex and other brain systems in depression |
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211 | (17) |
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211 | (3) |
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9.4.2 Orbitofrontal cortex |
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214 | (2) |
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9.4.3 Anterior cingulate cortex |
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216 | (3) |
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9.4.4 Posterior cingulate cortex |
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219 | (1) |
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220 | (3) |
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223 | (2) |
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9.4.7 Effective connectivity in depression |
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225 | (1) |
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9.4.8 Depression and poor sleep quality |
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226 | (2) |
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9.5 Possible subtypes of depression |
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228 | (1) |
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9.6 Implications for treatments |
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229 | (4) |
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9.6.1 Brain-based treatments |
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229 | (1) |
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9.6.2 Behavioural treatments and cognitive therapy |
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230 | (3) |
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9.7 Pharmacological treatments for depression |
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233 | (2) |
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233 | (2) |
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235 | (1) |
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9.8 Mania and bipolar disorder |
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235 | (4) |
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9.8.1 Mania, increased responsiveness to reward, and decreased responsiveness to non-reward |
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236 | (1) |
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9.8.2 Attractor networks, mania, increased responsiveness to reward, and decreased responsiveness to non-reward |
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237 | (1) |
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9.8.3 Other aspects of bipolar disorder |
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238 | (1) |
10 Rational vs emotional routes to action, and consciousness |
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239 | (17) |
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10.1 Multiple routes to action; reasoning vs emotion |
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239 | (6) |
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10.1.1 Some of the different routes to action produced by emotion-related stimuli |
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239 | (1) |
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10.1.2 Examples of some complex behaviours that may be performed implicitly |
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239 | (1) |
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10.1.3 A reasoning, rational, route to action |
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240 | (2) |
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10.1.4 The Selfish Gene vs The Selfish Phenotype |
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242 | (1) |
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10.1.5 Decision-making between the implicit and explicit systems |
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243 | (2) |
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10.2 A higher order syntactic thought theory of consciousness |
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245 | (4) |
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10.2.1 Rolls' higher order syntactic thought (HOST) theory of consciousness |
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245 | (3) |
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10.2.2 Adaptive value of processing in the system that is related to consciousness |
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248 | (1) |
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10.3 Comparison with other theories of consciousness |
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249 | (7) |
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10.3.1 Higher-order thought theories |
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249 | (2) |
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10.3.2 Oscillations and temporal binding |
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251 | (1) |
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10.3.3 A high neural threshold for information to reach consciousness |
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252 | (1) |
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10.3.4 James-Lange theory and Damasio's somatic marker hypothesis about feelings |
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253 | (1) |
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10.3.5 LeDoux's approach to emotion and consciousness |
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253 | (1) |
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10.3.6 Global workspace theories of consciousness |
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253 | (1) |
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10.3.7 Monitoring and consciousness |
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254 | (2) |
11 Conclusions, and broader issues |
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256 | (18) |
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256 | (8) |
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11.2 Selection of actions by explicit rational thought |
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264 | (1) |
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264 | (5) |
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11.4 Emotion and aesthetics |
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269 | (2) |
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271 | (3) |
A Glossary |
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274 | (4) |
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274 | (1) |
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A.2 Learning theory terms |
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275 | (3) |
References |
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278 | (33) |
Index |
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311 | |