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E-grāmata: Cancer-Causing Viruses and Their Inhibitors

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Edited by (National Institute of Technical Teachers Training and Research (NITTTR), Bhopal, India)
  • Formāts: 511 pages
  • Izdošanas datums: 16-May-2014
  • Izdevniecība: CRC Press Inc
  • ISBN-13: 9780429586064
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Cancer-Causing Viruses and Their InhibitorsPalielināt
  • Formāts: 511 pages
  • Izdošanas datums: 16-May-2014
  • Izdevniecība: CRC Press Inc
  • ISBN-13: 9780429586064
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Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles.

The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including:











Human T-cell leukemia virus type 1 (HTLV-1)





Hepatitis C virus (HCV)





EpsteinBarr virus (EBV)





Human papilloma virus (HPV)





Human herpes virus 8 (HHV-8)/Kaposis sarcoma-associated herpes virus (KSHV)





Human immunodeficiency virus (HIV/AIDS)





Oncolytic viruses

This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies.
Cancer Causing Viruses: An Introduction. Targeting Human T-Cell Leukemia
Virus Type 1: Pathogenesis and Treatment Strategies. Hepatitis C Virus and
Its Inhibitors: The Polymerase as a Target for Nucleoside and Nucleotide
Analogs. Mechanisms of Hepatitis C Virus Clearance by Interferon and
Ribavirin Combination: Lessons Learned from In Vitro Cell Culture. Hepatitis
B Virus Infection and Hepatocellular Carcinoma. EpsteinBarr Virus and
Treatment of Its Infection. Landscape of Papilloma Virus in Human Cancers:
Prevention and Therapeutic Avenues. Role of High-Risk Human Papillomaviruses
in Breast Carcinogenesis. Prospective Therapies of Genital Human
Papillomavirus Infections. Human Herpesvirus Type 8/Kaposi Sarcoma
Herpesvirus: An Overview of Viral Pathogenesis and Treatment of Associated
Diseases. Tea Polyphenolic Compounds against Herpes Simplex Viruses. HIV
Integrase Inhibitors: Qualitative and Quantitative Structure-Activity
Relationship Studies. Virus Wars: Oncolytic versus Oncogenic Viruses.
Oncolytic Viruses and Histone Deacetylase Inhibitors. Index.
Dr. Satya P. Gupta is a Professor in the Department of Applied Sciences at the National Institute of Technical Teachers Training and Research (NITTTR), Bhopal, India. Dr Gupta is one of the pioneers of QSAR (quantitative structure-activity relationship). He has published approximately 200 papers in various reputed journals on the topic and contributed dozens of authoritative reviews in prestigious review journals. This book is a result of his vast experience working in QSAR.
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