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E-grāmata: Cardiovascular Computed Tomography [Oxford Medicine Online E-books]

Edited by (Clinical Research Fellow, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, ), Edited by , Edited by (Consultant Cardiologist, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK), Edited by
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Cardiovascular computed tomography (CT) has rapidly become an important imaging tool in cardiology, and is now a compulsory component of the core curriculum for cardiology in UK and Europe. It is a complex imaging modality, however, with many aspects to master: CT theory, image acquisition and analysis, interpretation and reporting. This practical handbook is therefore essential reading for both training and reference for all cardiovascular CT users, including cardiologists, radiologists and radiographers, providing practical guidance on performing, analysing and interpreting cardiovascular CT scans in an accessible format.
Contributors xix
Symbols and abbreviations xxi
1 Development of cardiovascular CT
1(8)
Introduction
2(1)
Origins of X-ray computed tomography
3(1)
Scanner development
4(2)
Electron beam CT
6(3)
2 MSCT scanner components
9(12)
Gantry
10(2)
X-ray tube
12(2)
Collimators
14(1)
Detectors
15(1)
Detector terminology
16(2)
Detectors, data channels, and slices
18(3)
3 Technical principles of cardiovascular CT
21(18)
X-ray tube current
22(1)
X-ray tube voltage
23(1)
Scan pitch
24(2)
Spatial resolution
26(2)
Temporal resolution
28(2)
Multisegment reconstruction
30(2)
ECG gating (1)
32(2)
ECG gating (2)
34(2)
Acquisition mode
36(3)
4 Beyond 64-slice CT
39(10)
Limitations of 64-slice CT technology
40(2)
Cardiac CT with >64 slices
42(2)
Dual-source CT
44(2)
Single heartbeat CT
46(1)
Future technology
47(2)
5 Radiation physics, biology, and protection
49(20)
Interactions of X-rays with matter
50(1)
Biological effects of ionizing radiation
51(3)
Radiation dosimetry (1)
54(2)
Radiation dosimetry (2)
56(2)
Principles of radiation protection
58(2)
Patient dose and scanner design
60(2)
Scan parameters and radiation dose
62(2)
Radiation dose management
64(2)
Radiation dose optimization techniques
66(3)
6 Practical aspects of cardiovascular CT
69(14)
Justification and authorization
70(2)
Patient selection
72(2)
Preparing the patient
74(2)
Sample patient safety questionnaire
76(1)
Sample patient observation chart
77(1)
Heart-rate control
78(2)
Glyceryl trinitrate
80(1)
Preparing to scan
81(1)
Performing the acquisition
82(1)
7 Intravenous contrast media
83(16)
Iodinated contrast media (1)
84(2)
Coordinated contrast media (2)
86(2)
Adminstration of intravenous contrast
88(2)
Practical aspects
90(2)
Adverse contrast reactions (1)
92(2)
Adverse contrast reactions (2)
94(2)
Treatment of adverse contrast reactions
96(3)
8 Scan protocols
99(16)
Introduction
100(2)
Optimizing scan timing
102(4)
Coronary artery calcium scoring
106(2)
CT coronary angiography
108(2)
Gated CT pulmonary angiogram
110(1)
Gated CT pulmonary venography
111(1)
Prior to percutaneous aortic valve replacement
112(3)
9 Difficult scenarios
115(1)
Dysrhythmia (1)
116(2)
Dysrhythmia (2)
118(2)
Large patients
120(4)
Children (1)
124(3)
Children (2)
127(2)
10 Image reconstruction and processing
129(22)
Preparing to reconstruct
130(2)
Reconstruction of the CT image (1)
132(2)
Convolution filters and kernels
134(2)
Reconstruction of the CT image (2)
136(2)
CT numbers and windowing
138(2)
Image formats
140(2)
Multiplanar reformatting
142(2)
Curved multiplanar reformatting
144(2)
Maximum intensity projection
146(2)
3D image formats
148(3)
11 Sources of artefact
151(16)
Beam hardening
152(2)
Partial volume effect
154(2)
Motion artefact
156(2)
Data gaps and interpolation errors
158(2)
ECG interpretation errors
160(2)
Artefacts that mimic coronary stenoses
162(2)
Centreline tracking errors
164(3)
12 Cross-sectional anatomy of the thorax
167(10)
Introduction
168(2)
Cross-sectional anatomy of the thorax
170(7)
13 The coronary arteries and cardiac veins
177(14)
The coronary arterial circulation
178(2)
The coronary ostia and left coronary artery
180(2)
The right coronary artery
182(2)
The cardiac venous system
184(2)
Coronary sinus and its tributaries
186(5)
14 Imaging atherosclerotic plaque
191(18)
Pathology of atherosclerosis
192(2)
Coronary artery calcium scoring (1)
194(2)
Coronary artery calcium scoring (2)
196(2)
Imaging non-calcified plaque
198(2)
Quantifying luminal stenosis
200(2)
Diagnostic performance
202(2)
Comparison with invasive coronary angiography
204(2)
Comparison with other techniques
206(1)
Prognostic performance
207(2)
15 Coronary stent imaging
209(10)
Introduction
210(2)
The blooming effect
212(2)
Technical requirements
214(2)
Diagnostic performance
216(2)
Conclusion
218(1)
16 Coronary artery bypass graft imaging
219(10)
Introduction
220(2)
Scan acquisition
222(2)
Image analysis and interpretation
224(2)
Diagnostic performance
226(2)
Conclusions
228(1)
17 Evaluation of ventricular and atrial function
229(10)
Introduction
230(2)
Assessment of global left ventricular function
232(2)
Assessment of regional left ventricular function
234(2)
Right ventriculography
236(2)
Atrial assessment
238(1)
18 Ventricular pathology
239(20)
Introduction
240(2)
Investigating ischaemic left ventricular dysfunction
242(2)
Cardiomyopathies and myocardial infiltration
244(2)
Cardiac CT appearances in cardiomyopathies
246(2)
Cardiac CT in `unclassified' cardiomyopathies and myocardial infiltrations
248(1)
Cardiac masses
249(1)
Benign cardiac tumours
250(4)
Malignant cardiac tumours
254(2)
Cardiac pseudotumours
256(3)
19 Evaluation of myocardial scarring and perfusion
259(14)
Introduction
260(2)
Contrast pharmacokinetics
262(2)
Scan acquisition: technical aspects
264(2)
Image interpretation
266(2)
Delayed CCT in clinical practice
268(2)
Evaluation of myocardial perfusion
270(3)
20 Evaluation of the left atrium and pulmonary veins
273(10)
Introduction
274(1)
Cardiac CT prior to electrophysiology procedures
275(1)
Left atrium and pulmonary veins
276(2)
Other relevant anatomy
278(2)
Substrates for ventricular dysrhythmia
280(1)
Template report for pre-electrophysiology CT
281(2)
21 Valve imaging
283(36)
Introduction
284(1)
Acquisition for valve imaging
285(1)
Post-processing
286(3)
Multiphase reconstruction
289(1)
Artefacts
290(2)
Aortic stenosis (1)
292(2)
Aortic stenosis (2)
294(2)
Aortic regurgitation
296(2)
Mitral stenosis
298(2)
Mitral regurgitation (1)
300(2)
Mitral regurgitation (2)
302(2)
Tricuspid regurgitation
304(4)
Tricuspid stenosis
308(2)
Pulmonary regurgitation
310(2)
Pulmonary stenosis
312(2)
Prosthetic valves (1)
314(2)
Prosthetic valves (2)
316(3)
22 Pericardial disease
319(12)
The pericardium
320(2)
Pericardial imaging
322(2)
Pericardial effusion
324(2)
Constrictive pericarditis
326(2)
Pericardial tumours and masses
328(2)
Congenital absence of pericardium
330(1)
23 Congenital heart disease
331(40)
Introduction
332(2)
Sequential segmental analysis
334(2)
Technical considerations in congenital cardiovascular CT
336(2)
Anomalous coronary arteries (1)
338(2)
Anomalous coronary arteries (2)
340(1)
Myocardial bridging
341(1)
Coronary assessment in adult congenital heart disease
342(2)
Other congenital coronary anomalies
344(2)
Atrial septal defects
346(2)
Ventricular septal defects
348(2)
Atrio-ventricular septal defects
350(2)
Patent ductus arteriosus
352(2)
Other congenital aortic abnormalities
354(2)
Transposition of the great arteries
356(2)
Congenitally corrected transposition of the great arteries
358(2)
Anomalous pulmonary venous connection
360(2)
Major aorto-pulmonary collateral arteries
362(2)
Tetralogy of Fallot
364(2)
The Functionally univentricular heart
366(2)
Congenital valve pathology
368(3)
24 Non-cardiac findings on cardiac CT
371(24)
Introduction
372(2)
Lung parenchyma
374(2)
Lung nodules
376(2)
Parenchymal lung disease
378(2)
Mediastinal anatomy
380(2)
Mediastinal pathology
382(2)
Differential diagnosis of mediastinal tumours and masses
384(4)
Patterns of mediastinal lymphadenopathy
388(202)
Chest wall and pleural pathology
390(1)
Upper abdominal pathology
391(1)
Conclusions
392(3)
25 Thoracic aortic imaging
395(24)
Normal anatomy of the thoracic aorta
396(4)
Aortic aneurysms and dilatation
400(2)
Aortic dissection
402(2)
Aortic intramural haematoma
404(2)
Coarctation of the aorta
406(302)
Other congenital aortic abnormalities
408(1)
Aortitis
409(1)
Pre- and post-surgical assessment
410(2)
Assessment prior to transcatheter aortic valve implantation (1)
412(4)
Assessment prior to transcatheter aortic valve implantation (2)
416(3)
26 Pulmonary artery imaging
419(10)
Introduction
420(2)
CT pulmonary angiography
422(3)
Peripheral venous imaging
425(1)
Chronic pulmonary hypertension
426(3)
27 Combined multivessel angiography
429(4)
The triple rule-out
430(2)
Combined CT coronary and pulmonary angiography
432(1)
28 Peripheral arterial imaging
433(12)
Introduction
434(2)
CT technique
436(2)
Abdominal aorta and branches
438(2)
Renal artery Imaging
440(2)
Carotid artery imaging
442(3)
29 Systemic veins
445(10)
Introduction
446(2)
Systemic venous anatomy
448(4)
Imaging the systemic veins
452(3)
30 Guidelines, accreditation, and certification
455(10)
Cardiovascular CT guidelines
456(2)
Appropriate use criteria for cardiovascular CT
458(2)
Cardiac CT in other clinical guidelines
460(2)
Accreditation in cardiovascular CT
462(2)
Certification in cardiovascular CT
464(1)
31 Comparison of multimodality imaging
465(36)
Introduction
466(2)
Basis of functional imaging: coronary physiology and stress testing
468(2)
Cardiac stress for functional imaging
470(2)
Myocardial perfusion single photon emission CT (1)
472(2)
Myocardial perfusion single photon emission CT (2)
474(2)
Myocardial perfusion single photon emission CT in clinical practice
476(2)
Myocardial perfusion positron emission tomography (PET)
478(476)
Radionuclide ventriculography
480(2)
Echocardiography
482(2)
Echocardiography in clinical practice
484(2)
Stress echocardiography
486(2)
Cardiovascular magnetic resonance imaging
488(2)
Cardiovascular magnetic resonance in clinical practice
490(4)
Stress cardiovascular magnetic resonance imaging
494(2)
Practical aspects of imaging techniques: infrastructure requirements
496(2)
Practical aspects of imaging techniques: patient-related issues
498(3)
Index 501
Ed Nicol is a Consultant Cardiologist at the Royal Brompton Hospital, and National Heart and Lung Institute, Imperial College, London. He has wide experience in cardiovascular imaging including cardiovascular CT, MRI, echocardiography and nuclear cardiology. He was involved in establishing the clinical cardiovascular CT service at both the Royal Brompton and the Royal Berkshire Hospitals.

James Stirrup is a Clinical Research Fellow in Cardiac Imaging at the Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London. He has experience in nuclear cardiology and cardiovascular computed tomography, holding both CBNC and CBCCT certification in addition to Level 3 accreditation from the Society for Cardiovascular Computed Tomography.

Andrew Kelion is Consultant Cardiologist and Director of Imaging at Harefield Hospital, Harefield, UK. He qualified from the University of Oxford, and trained in cardiology in London, Reading and Oxford. He is an experienced nuclear and echo cardiologist. He is a former President of the British Nuclear Cardiology Society and co-author of the Oxford Handbook of Nuclear Cardiology.

Simon Padley is a Consultant Radiologist at the Royal Brompton Hospital and Chelsea and Westminster Hospital. He qualified from Westminster Medical School, University of London, and trained in Radiology in London, Cambridge and Vancouver. He is an experienced cardiothoracic imager and interventionalist.