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Cardiovascular Pathology 4th edition [Hardback]

Edited by (Professor, University of Toronto and Director, Division of Pathology, Deptartment of Laboratory Medicine and Pathobio), Edited by (Professor of Pathology and Laboratory Medicine at the University of Texas Health Science Center, Houston, TX, USA)
  • Formāts: Hardback, 830 pages, height x width: 276x216 mm, weight: 2540 g
  • Izdošanas datums: 05-Jan-2016
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0124202195
  • ISBN-13: 9780124202191
Citas grāmatas par šo tēmu:
Cardiovascular Pathology 4th editionPalielināt
  • Formāts: Hardback, 830 pages, height x width: 276x216 mm, weight: 2540 g
  • Izdošanas datums: 05-Jan-2016
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0124202195
  • ISBN-13: 9780124202191
Citas grāmatas par šo tēmu:
Permanent link: https://www.kriso.lv/db/9780124202191.html
Keywords:

Cardiovascular Pathology, Fourth Edition, provides users with a comprehensive overview that encompasses its examination, cardiac structure, both normal and physiologically altered, and a multitude of abnormalities. This updated edition offers current views on interventions, both medical and surgical, and the pathology related to them.

Congenital heart disease and its pathobiology are covered in some depth, as are vasculitis and neoplasias. Each section has been revised to reflect new discoveries in clinical and molecular pathology, with new chapters updated and written with a practical approach, especially with regards to the discussion of pathophysiology. New chapters reflect recent technological advances with cardiac devices, transplants, genetics, and immunology. Each chapter is highly illustrated and covers contemporary aspects of the disease processes, including a section on the role of molecular diagnostics and cytogenetics as specifically related to cardiovascular pathology.

  • Serves as a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows of pathology, cardiology, cardiac surgery, and internal medicine
  • Offers new organization of each chapter to enable uniformity for learning and reference: Definition, Epidemiology, Clinical Presentation, Pathogenesis/Genetics, Light and Electron Microscopy/Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications
  • Features six new chapters and expanded coverage of the normal heart and blood vessels, cardiovascular devices, congenital heart disease, tropical and infectious cardiac disease, and forensic pathology of the cardiovascular system
  • Contains 400+ full color illustrations and an online image collection facilitate research, study, and lecture slide creation

Papildus informācija

This updated book provides an encyclopedic translational reference on cardiovascular disease that includes a comprehensive overview encompassing its examination, cardiac structure both normal and physiologically altered, and a multitude of abnormalities to offer users the most current views on interventions both medical and surgical, and the pathology related to them. Customers buy the Print + Electronic product together!
Contributors xi
Preface xiii
Acknowledgments xv
1 Anatomic Considerations and Examination of Cardiovascular Specimens (Excluding Devices)
1(56)
J.J. Maleszewski
C.K. Lai
J.P. Veinot
Gross Examination of the Heart
2(17)
Examination of Surgical Cardiovascular Specimens
19(3)
Microscopic Examination of the Blood Vessels and Heart
22(29)
References
51(6)
2 Age-related Cardiovascular Changes and Diseases
57(28)
A. Seki
M.C. Fishbein
Nonspecific Cardiovascular Changes of Aging
57(7)
Changes in the Conduction System
64(1)
Changes in Arteries
65(3)
Age-related Diseases
68(9)
Disorders of Premature Aging
77(1)
Telomere
78(1)
References
79(6)
3 Vascular Pathobiology: Atherosclerosis and Large Vessel Disease
85(40)
S. Xu
M. Bendeck
A.I. Gotlieb
Introduction to Atherosclerosis
86(1)
Epidemiology and Risk Factors
86(2)
Gross and Microscopic Morphology of the Fibroinflammatory Lipid Plaque
88(3)
Steps in Atherosclerotic Plaque Formation and Complications
91(5)
Cellular Function and Pathways in Atherogenesis
96(15)
Nonatherosclerotic Diseases of the Aorta
111(4)
References
115(10)
4 Diseases of Small and Medium-sized Blood Vessels
125(44)
J.R. Stone
Introduction
126(1)
Vascular Activation and Common Vascular Pathologic Changes
126(1)
Congenital Vascular Diseases
127(1)
Genetic Vascular Disorders
128(4)
Endocrine/Metabolic Vascular Disorders
132(1)
Vasculitis
133(9)
Infection
142(3)
Toxic Vasculopathies
145(1)
Coagulopathic Disorders
145(2)
Hypertension
147(2)
Vascular Deposition Disorders
149(3)
Intimai Proliferative Diseases
152(2)
Arterial Dissections
154(2)
Miscellaneous Conditions
156(3)
Disorders of Veins
159(3)
References
162(7)
5 Aneurysms of the Aorta: Ascending, Thoracic and Abdominal and Their Management
169(44)
E. Ladich
J. Butany
R. Virmani
Introduction
170(1)
Normal Anatomy and Histology of the Aorta
170(1)
Aging Changes of the Aorta
171(1)
Thoracic Aortic Aneurysms
172(4)
Etiology and Pathologic Findings
176(14)
Clinical Presentation and Natural History
190(1)
Abdominal Aortic Aneurysm
190(4)
Aortic Dissection
194(7)
Management
201(3)
References
204(9)
6 Fundamental Principles in Cardiovascular Genetics
213(26)
M.A. Seidman
R.N. Mitchell
Genetic Variation
214(2)
Modern Molecular Diagnostics
216(12)
Identifying the Genetic Basis of Cardiovascular Disease
228(2)
Representative Genetic Cardiovascular Conditions
230(1)
Molecular Diagnostics in Cardiovascular Pathology Practice
231(4)
References
235(4)
7 Myocardial Ischemia and Its Complications
239(32)
G.A. Fishbein
M.C. Fishbein
L.M. Buja
Definition and History
239(1)
Clinical Manifestations
240(1)
Epidemiology
241(1)
Biochemical Changes with Ischemia and Biochemical Markers
241(1)
Ultrastructural Evolution of Acute Ischemic Injury
242(2)
Cellular and Subcellular Mechanisms of Myocardial Injury
244(1)
Microscopic Evolution of Acute Ischemic Injury
245(4)
Morphology of Coronary Arteries and Plaques
249(2)
Tako-Tsubo Cardiomyopathy
251(1)
Gross Evolution of Acute Ischemic Injury
251(1)
Patterns of MI
252(1)
Phenomena Associated with Ischemic Injury
253(3)
Reperfusion of Ischemic Myocardium
256(1)
Complications of MI
257(4)
Recognition and Quantification of Acute Ischemic Injury
261(2)
Pathology of Interventions
263(2)
Pathophysiological and Pharmacological Interventions
265(1)
Molecular Biology of Myocardial Ischemia
265(1)
References
266(5)
8 Pathophysiology of Heart Failure and an Overview of Therapies
271(70)
J.M. Berthiaume
J.A. Kirk
M.J. Ranek
R.C. Lyon
F. Sheikh
B.C. Jensen
B.D. Hoit
J. Butany
M. Tolend
V. Rao
M.S. Willis
Overview of Heart Failure
272(4)
Pathophysiology of HF
276(5)
Neurohormonal Alterations in HF
281(2)
Signaling Responses to Various Stimuli During HF
283(10)
HF-related Alterations in Cellular Function and Biochemical Pathways
293(6)
Metabolic Remodeling in HF
299(7)
Summary of HF
306(1)
Therapeutic Management of HF
306(18)
References
324(17)
9 Myocarditis
341(20)
M.A. Seidman
B.M. McManus
Definition of Myocarditis
341(1)
Diagnosis of Myocarditis
342(3)
Histopathologic Patterns of Myocarditis
345(4)
Etiologies of Myocarditis
349(7)
Treatment of Myocarditis
356(1)
References
357(4)
10 Pathology of Sudden Death, Cardiac Arrhythmias and Conduction System
361(74)
G. Thiene
S. Rizzo
C. Basso
Sudden Death
362(37)
Cardiac Conduction System
399(18)
Atrial Fibrillation
417(3)
Appendix Guidelines for Postmortem Study of Sudden Death
420(3)
Acknowledgments
423(1)
References
423(12)
11 Cardiomyopathies
435(50)
G. D'Amati
C. Giordano
Definition and Classification of Cardiomyopathies
436(1)
Dilated Cardiomyopathy
437(9)
Hypertrophic Cardiomyopathy
446(14)
Arrhythmogenic Cardiomyopathy
460(8)
Restrictive Cardiomyopathy
468(8)
Others
476(3)
References
479(6)
12 Valvular Heart Disease
485(44)
P. Vaideeswar
J. Butany
Introduction
485(1)
Functional Anatomy
486(1)
Types of Valvular Dysfunction
487(39)
References
526(3)
13 Cardiac Valve Replacement and Related Interventions
529(48)
F.J. Schoen
J. Butany
General Considerations
530(10)
Valve-related Complications: Clinical Importance, Morphology, Secondary Effects, and Pathogenesis
540(11)
Other Tissue Valve Substitutes
551(4)
Catheter-based Valve Implantation
555(3)
Valve Repair and Valve Sparing Procedures
558(4)
New Developments and Future Considerations
562(1)
Pathologic Considerations in Analysis of Heart Valve Substitutes
562(6)
Disclosure
568(1)
Appendix
568(1)
References
569(8)
14 The Pathology of Cardiovascular Interventions and Devices for Coronary Artery Disease, Vascular Disease, Heart Failure, and Arrhythmias
577(34)
L.M. Buja
F.J. Schoen
Endovascular Therapies and Myocardial Revascularization
578(13)
Aortic and Peripheral Vascular Replacement and Reconstruction
591(7)
Cardiac Assist and Replacement
598(2)
Arrhythmia Control
600(5)
References
605(6)
15 Congenital Heart Disease: Pathology, Natural History, and Interventions
611(34)
G. Ottaviani
L.M. Buja
Introduction
611(1)
Epidemiology and Etiology
612(3)
Embryology of the Cardiovascular System
615(5)
Clinical Features and Consequences
620(1)
Specific Forms of CHD
621(18)
Surgical and Nonsurgical Interventions for Treatment of CHD
639(2)
CHD in the Adult
641(3)
Natural History of CHD without and with Interventions
644(1)
References
644(1)
16 The Pericardium and Its Diseases
645(34)
P. Singhal
P. Thavendiranathan
J. Butany
Anatomy
650(1)
Physiology
650(1)
Histology
650(1)
Echocardiography
651(1)
Pericardiocentesis and Biopsy
651(1)
Congenital Abnormalities
651(3)
Pericardial Effusion After Cardiac Surgery
654(1)
Pneumopericardium
654(9)
Early Postmyocardial Infarction Pericarditis and Dressler Syndrome
663(1)
Iatrogenic and Traumatic Pericarditis
664(10)
References
674(5)
17 Pathology of Cardiac Transplantation
679(42)
C.D. Tan
M.K. Halushka
E.R. Rodriguez
General Clinicopathologic Considerations
680(1)
Pathology of the Explanted Recipient Heart
681(2)
Pathology of the Donor Heart
683(1)
Pathology of the Allograft
684(22)
Heart Transplantation in Combination with Other Organs
706(1)
Pathological Review of an EMB
706(3)
Approach to the Examination of a Failed Allograft
709(2)
Future Considerations
711(1)
References
711(10)
18 Toxins and the Heart
721(14)
M.C. Fishbein
Introduction
721(1)
Endocardium
722(1)
Myocardium
723(5)
Pericarditis
728(1)
Primary Conduction System Abnormalities
729(1)
Coronary Artery Lesions
730(1)
Cocaine-Other Drug Interactions
731(1)
Drugs to Treat Attention Deficit-Hyperactivity Disorders
731(1)
Antipsychotic Medications
731(1)
Nonsteroidal Anti-inflammatory Drugs
731(1)
Myocardial Toxins as a Cause of Death
732(1)
References
732(3)
19 Tumors of the Cardiovascular System: Heart and Blood Vessels
735(38)
E. Ladich
R. Virmani
Incidence and Classification
736(1)
Clinical Symptoms
737(1)
Reactive Cardiac Masses and Pseudotumors
737(3)
Ectopias
740(2)
Hamartomas and Benign Neoplasms
742(1)
Hamartomas of Cardiac Muscle
743(2)
Benign Fatty Tumors
745(1)
Benign Tumors of Myofibroblastic Tissue
746(1)
Miscellaneous Benign Fibrous Tumors
747(1)
Cardiac Myxoma
748(5)
Benign Neural Neoplasms
753(2)
Malignant Tumors
755(5)
Metastatic Tumors
760(2)
Sarcomas of the Great Vessels
762(4)
References
766(7)
20 Forensic Aspects of Cardiovascular Pathology
773(26)
B. Sampson
J.L. Hammers
Investigative Information
773(1)
General Changes
774(1)
Primary Diseases/Injuries of the Heart
775(6)
Cardiomyopathies, Myocarditis, and Genetic Causes of SCD
781(2)
Anomalies and Diseases of the Aorta and Coronary Arteries
783(4)
Diseases of the Cardiac Valves
787(5)
Ancillary Studies
792(1)
Sudden Death Following Surgery and Medical Procedures
793(1)
Organ and Tissue Harvesting
794(1)
Cardiovascular Pathology Consultation
795(1)
Summary
795(1)
References
796(3)
Index 799
Professor of Pathology and Laboratory Medicine, Medical School, The University of Texas Health Science Center at Houston (UTHealth); Distinguished Teaching Professor, The University of Texas System; Executive Director, The TMC Library; Editor-in-Chief, Cardiovascular Pathology (the official journal of the Society for Cardiovscular Pathology)

Dr. Buja MD is a Professor of Pathology and Laboratory Medicine at the University of Texas Health Science Center at Houston. His subspecialty interest is cardiovascular pathology with research interests in myocardial cell injury, myocardial ischemia, atherosclerosis and cardiomyopathies.Dr. Buja teaches medical students, medical residents, clinical fellows, graduate students and research post-doctoral fellows. He also conducts a clinical practice in cardiovascular pathology providing staffing of autopsy cases and surgical pathology consultation of cardiac and vascular cases and interpretation of myocardial biopsies from referrals. He directs a cardiovascular pathology fellowship approved by the Texas Medical Board.He is the editor-in-chief of Cardiovascular Pathology, the official journal of the Society for Cardiovascular Pathology.He also serves as the Executive Director of The Texas Medical Center Library located adjacent to the medical school. Consultant Cardiovascular Pathologist/Director Autopsy Services Co-Editor-in-Chief, Cardiovascular Pathology, Guest Editor, Seminars in Diagnostic Pathology Secretary-Treasurer, WASPaLM, Professor, University of Toronto & Director, Division of Pathology,Dept. of Laboratory Medicine and Pathobiology, University Health Network / Laboratory Medicine Program Toronto General Hospital,Toronto, Ontario, Canada.

Dr. Butany is Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto, Canada and Director of the Division of Pathology in the Department. He is a Staff Cardiovascular Pathologist at the University Health Network (Toronto General Hospital Site), and Director of Autopsy Services. His investigative work has primarily been based on clinical investigations and outcomes and collaboration with clinical colleagues in basic and applied research. His major interest has been prosthetic heart valves. Dr. Butany has been involved in teaching at the undergraduate and post-graduate levels, including medical students, pathology residents, cardiology residents and cardiac surgery residents and fellows. He is a founding member of the Society for Cardiovascular Pathology and served as the president from 2007-2009). He has been Co-Editor-in-Chief of Cardiovascular Pathology, the official journal of the Society of Cardiovascular Pathology and continues to serve on its Editorial Board.