Klientu atbalsts: 27018494

Grāmatu iegāde | Jauns profils | Ienākt

E-grāmata: Cell Wall Deficient Forms: Stealth Pathogens

4.80/5 (9 ratings by Goodreads)

Lida H. Mattman

Formāts: 448 pages
Izdošanas datums: 26-Oct-2000
Izdevniecība: CRC Press Inc
Valoda: eng
ISBN-13: 9781482275216

Citas grāmatas par šo tēmu:

Bacteriology (non-medical)

Formāts - PDF+DRM
Cena: 288,03 €*
* ši ir gala cena, t.i., netiek piemērotas nekādas papildus atlaides
Ielikt grozā
Pievienot vēlmju sarakstam
Šī e-grāmata paredzēta tikai personīgai lietošanai. E-grāmatas nav iespējams atgriezt un nauda par iegādātajām e-grāmatām netiek atmaksāta.
Bibliotēkām

Formāts: 448 pages
Izdošanas datums: 26-Oct-2000
Izdevniecība: CRC Press Inc
Valoda: eng
ISBN-13: 9781482275216

Citas grāmatas par šo tēmu:

Bacteriology (non-medical)

DRM restrictions

Kopēšana (kopēt/ievietot):

nav atļauts
Drukāšana:

nav atļauts
Lietošana:

Digitālo tiesību pārvaldība (Digital Rights Management (DRM))
Izdevējs ir piegādājis šo grāmatu šifrētā veidā, kas nozīmē, ka jums ir jāinstalē bezmaksas programmatūra, lai to atbloķētu un lasītu. Lai lasītu šo e-grāmatu, jums ir jāizveido Adobe ID. Vairāk informācijas šeit. E-grāmatu var lasīt un lejupielādēt līdz 6 ierīcēm (vienam lietotājam ar vienu un to pašu Adobe ID).

Nepieciešamā programmatūra
Lai lasītu šo e-grāmatu mobilajā ierīcē (tālrunī vai planšetdatorā), jums būs jāinstalē šī bezmaksas lietotne: PocketBook Reader (iOS / Android)

Lai lejupielādētu un lasītu šo e-grāmatu datorā vai Mac datorā, jums ir nepieciešamid Adobe Digital Editions (šī ir bezmaksas lietotne, kas īpaši izstrādāta e-grāmatām. Tā nav tas pats, kas Adobe Reader, kas, iespējams, jau ir jūsu datorā.)

Jūs nevarat lasīt šo e-grāmatu, izmantojot Amazon Kindle.

Numerous infectious diseases are described as idiopathic, meaning that "the cause is a complete mystery." For many idiopathic diseases, the causes become clear when certain techniques are applied to the patient's blood or other tissues. Cell Wall Deficient Forms: Stealth Pathogens, Third Edition describes these techniques. In the case of tuberculosis, a disease that has recently regained importance because the strains have acquired antibiotic resistance, the book describes a method that is widely used abroad. This method typically renders the diagnosis within 72 hours. The book examines a plethora of issues and provides answers to the following questions:

What organism should be added to the childhood vaccine, especially for boys?

What bacteria in its pleomorphic state is found in direct smears of synovial fluid of rheumatoid arthritis cases?

In which chronic diseases ( presently considered as being of unknown origin) is an acid-fast organism routinely found in smears of 72 hour blood cultures?

Which "bacterium" has a life cycle in the human erythrocyte as complex as that of Plasmodium malaria?

Which common pathogen's L Form can permanently damage myocardium mammaliam? Cell Wall Deficient Forms: Stealth Pathogens, Third Edition discloses significant aspects of microbiology, aspects that are not taught, and which go unrecognized in the clinical laboratory.

History

Introduction

(6)

References

(2)

Definitions

Introduction

(3)

L-Phase Variant

(1)

Protoplasts

(1)

Spheroplasts

(1)

Transitionals

(1)

L-Bodies

(1)

Filtrable Forms

(1)

Pleomorphs

(1)

Induction

(1)

Reversion

(1)

Gymnoplasts

(1)

L-Dependents

(1)

References

(1)

Comparing Mycoplasma, CWD Forms, and Rickettsia

Introduction

(1)

Similarities Relating Mycoplasma and CWD Forms

(2)

Fine Structure

(1)

Atmosphere Optimum for Growth

(1)

Serum Requirements

(1)

Ribosomes

(1)

Hemadsorption

(1)

Sugar Phosphotransferase

(1)

pH Requirements

(1)

Biochemical Properties Shared

(1)

Factors Distinguishing Mycoplasma from CWD Forms

(3)

Growth in Liquid Culture

(1)

Colonial Appearance

(1)

Sensitivity to Penicillin

(1)

Nucleic Acid Homology

(1)

Biochemical Activities

(1)

Bacteriocin Susceptibility

(1)

Wall-Associated Structures

(1)

Pathogenicity

(1)

Summary

(1)

References

(2)

Propeties and Peculiarities

Morphology

(1)

The L-Cycle

(1)

The Nucleoid

(1)

Variation in Development of Units

(1)

Syncytia

(1)

Halos

(1)

Substrate and Morphology: Order from Chaos

(1)

Amino Acids and Peptones

(1)

Carbohydrates Influence Morphology

(1)

Ions

(1)

Colonial Morphology

(1)

Growth at Varying Depths in Agar

(1)

Peculiarities in Corynebacterium diphtheria Colonies

(1)

Variation in CWD Colonies, Including Rough and Smooth

(1)

Pigments

(1)

Water-Soluble Pigments

(1)

Water-Insoluble Pigments

(1)

Luminescence and Fluorescence

(1)

Inhibition by Classical Bacteria

(1)

Generation Time

(1)

Osmotic Fragility

(1)

Resistance of CWD Forms to Physical Factors

(1)

Effect of Lytic Agents

(1)

Are All Wall Deficient Variants of a Strain Identical?

(1)

L-Forms as Plasmid Recipients

(1)

Electrical Properties

(1)

Role of CWD Forms in Nutrition of Amoeba

(1)

Why are Some Strains Highly Susceptible to CWD Form Induction?

(1)

Summary

(1)

References

(5)

Composition of Cell Wall Deficient Forms

Components

(2)

Loss of Murein Components

(1)

Substitutes for the Rigid Murein Layer

(1)

Retention of Murein Components

(1)

Amino Sugars in L-Forms

(1)

DAP in the Cell Wall

(1)

Teichoic Acid

(1)

Loss of Polysaccharides and Protein

(1)

Cytoplasmic Membrane

(1)

Total Lipid

(1)

Cholesterol in the Membrane

(1)

Membrane Protein in L-Form

(1)

Whole Cell Analyses

(2)

Lipopolysaccharides and Lipids

(1)

Composition Changes with Salts in Menstruum

(1)

Polysaccharides

(1)

Group-Specific Polysaccharides

(1)

Teichoic Acids

(1)

RNA

(1)

Ribosome Positioning

(1)

Phosphorus in L-Forms

(1)

Capsular Antigens

(1)

DNA of Spore Spheroplasts

(1)

Summary

(1)

References

(4)

Disclosures by Electron Microscopy

Introduction

(1)

A Close-Up View of the Wall

(3)

Protoplasts

(2)

Spheroplasts and L-Forms

(1)

Mureinoplasts

(1)

The Nucleoid

(1)

Changes in the Cytoplasmic Membrane

(1)

Mesosomes

(1)

Excursions of the Cytoplasmic Membrane

(1)

New Structures

(1)

Vacuoles between Wall and Membrane

(1)

New Capsules

(1)

Identifying-Structures and Antigens in Electron Micrographs

(1)

Microtubules in Group D Streptococci

(1)

Inclusions in Clostridium botulinum L-Forms

(1)

Ferritin-Labeled Antibody

(1)

Do All Variants Survive Fixation for Electron Microscopy?

(1)

Freeze-Etching

(1)

Scanning Beam Electron Microscope Studies

(1)

Summary

(1)

References

(4)

Public Health and Nosocomial Facets

Salmonella and Shigella Carriers

(1)

L-Forms in the Clinical Laboratory

(1)

CWD Forms in Water Supplies

(1)

Wall Deficient Bacteria in Foods

(4)

L-Forms in Fish

(1)

Flora of Ground Meats

(3)

Butter

(1)

Milk

(1)

CWD Bacteria in Diseases of Vegetables

(1)

Nosocomial Acquisition of Chlamydia

(1)

``Sterile'' Water in Hospitals

(2)

Pseudomonas aeruginosa Contamination

(2)

Significant Factors in Successful Contamination with P. aeruginosa

(1)

Detecting the Pseudomonas Variants

(1)

Reversion

(1)

Other ``Water Bugs''

(1)

Sterilization of Instruments

(1)

Possibility of CWD Stages in Toxoid

(1)

Plague-Carrying Rodents

(1)

Comments

(1)

References

(2)

Immunology

Detection of Typhoid Cases and Carriers by Their Spheroplast Antibody or Antigenemia

(1)

Wall Deficient Forms as Vaccines

(1)

Spheroplast Production by Lysozyme without Antibody

(1)

Spheroplasts in Identification of Pasteurella multocida Subtypes

(1)

Antibody-Complement in Induction of Variants

(1)

Spheroplasting by Leukocyte Products or Growth within Phagocytic Cells

(1)

Mycobacteria and Leukocyte Products

(1)

Immunogens

(1)

Antigens Unique to the CWD Variants

(1)

Antigens Retained by CWD Variants

(1)

Tissue Damage from CWD Antigens

(1)

Antigens Missing or Minimized in the CWD Stage

(1)

Interferon Production in Chicks

(1)

Interleukins

(1)

Activation of the HIV Terminal Repeat

(1)

Mitogens

(1)

Phagocytosis

(1)

Depression or Stimulation of the Major Immune Branches

(1)

Graft vs. Host Disease

(1)

Increase in Exudate Cells

(1)

Immortalizing Human Lymphocytes

(1)

Loss of Immunity in Burned Tissue

(1)

Summary

(1)

References

(4)

Induction by Antibiotics, Organic Compounds, and Miscellaneous Factors

Mechanisms that Result in Cell Wall Deficiency

(1)

Induction of CWD Forms by Antibiotics In Vitro

(3)

Responsive Bacteria

(1)

Penicillin Induction as a Tool in Identifying a Classical Bacterium

(2)

Formation of Wall Deficient Variants vs. Bacterial Death

(1)

Relative Inducing Ability of Antibiotics

(2)

Chloramphenicol

(1)

Erythromycin

(1)

Tetracyclines

(1)

Lysostaphin

(1)

Nystatin and Amphotericin B

(1)

Snail Juice Induces Cell Wall Deficiency

(1)

Dyes as Agents which Promote Cell Wall Deficiency of Microorganisms

(1)

Effects of Pretreatments on Susceptibility to Induction

(1)

Result of Numerous Transfers In Vitro

(1)

In Vivo Induction of Cell Wall Deficient Microbes

(1)

Summary

(2)

References

(4)

Reversion and Revertants

To Revert or Not to Revert?

(1)

In Vitro Reversion Techniques

(4)

Omission of the Inducing Agent

(1)

Exposure to an Antibiotic

(1)

Changes in Nutrition

(1)

Role of Serum, Yeast, and Vitamins

(1)

Addition of Amino Sugars

(1)

Spermine

(1)

Exclusion of All Large Molecules

(1)

Physical Factors

(1)

Support by Firm Agar or Gelatin

(1)

Support by Cellulose Filter Pads

(1)

Atmosphere

(1)

Temperature

(1)

Alternation of Culture Menstrua

(1)

Mucin

(1)

Reversion Stimulated by Products from Microbes

(1)

Mycobacterial Reversion

(1)

A Muralytic Enzyme

(1)

Aging with or without Transfers

(1)

Concentrated Populations

(1)

Mutagens

(1)

Stablizing Induced L-Forms

(1)

Characteristics of Revertants

(1)

Inhibition of Reversion

(3)

Inhibition of Reversion of Yeast Protoplasts by 2-Deoxyglucose

(1)

Presence of Serum

(1)

Destroying the Reversion Inhibitor

(3)

Morphology of the Reverting Organism

100

(1)

In Vivo Manipulations

100

(1)

Chick Embryo Inoculation

100

(1)

Injections in Mice

100

(1)

Summary

100

(1)

References

101

(4)

Septicemia and Cardiopathies

Endocarditis

105

(6)

Subacute Bacterial Endocarditis

105

(1)

SBE with CWD Propionibacterium

105

(3)

Endocarditis Due to CWD Pseudomonas

108

(1)

Acute Endocarditis

108

(1)

Administration of Antibiotic before Taking Blood Cultures

109

(1)

Following Administration of an Antibiotic Inhibitory to the Classical Pathogen

110

(1)

Infections Following Insertion of Prosthetic Cardiac Valves

110

(1)

Nutritionally Variant Streptococci

110

(1)

Septicemia

111

(1)

Myocarditis and Combined Myocarditis and Endocarditis

112

(1)

Hypertonic Media

112

(1)

Where Positive ``Negative'' Cultures can be Found

112

(1)

Skip Cultures in Septicemia

112

(1)

Allergy and Other Conditions Associated with CWD Bacteremia

113

(1)

Summary

113

(1)

References

113

(4)

Intracellular Growth of CWD Forms

Intraerythrocytic Cell Wall Deficient Forms

117

(3)

Erythrocyte Parasitism Associated with Disease

117

(2)

Postulations Concerning Auto-Immune Disease

119

(1)

The Most Hypnotic of all Intraerythrocytic Forms

119

(1)

CWD Forms within Platelets

120

(1)

CWD Forms in Circulating Leukocytes

120

(2)

Intracellular Growth of CWD Forms in Host Tissue

122

(1)

Treponema

122

(1)

Borrelia

122

(1)

Fowl Spirochetosis

123

(1)

Vibrio

123

(1)

Bordetella

123

(1)

Intracellular Growth of CWD Forms in Tissue Culture

123

(1)

Changes in the Microbial Variant in the Tissue Culture Cells

123

(1)

CWD-Induction by Inoculation of Classical Bacteria into Tissue Culture

124

(1)

Salmonella typhi in Tissue Culture

124

(1)

L-Forms in Tissue Culture Cells

124

(1)

CWD Forms as Tissue Culture Contaminants

124

(1)

Growth of Bacteria within Fungi

124

(1)

Summary

125

(1)

References

125

(4)

L-Forms in Thrombi

L-Forms in Surgery and Contraception

129

(1)

Chlamydia in Coronary Thrombosis

129

(2)

Comment

131

(1)

References

131

(2)

Urinary Tract Infections: Idiopathic Hematuria, Interstitial Cystitis, and Others

Disease in Man

133

(6)

Chronic Pyelonephritis as a Disease with Occult Organisms

133

(1)

Treated and Untreated Cases Show Variants

133

(1)

Renal Fanconi Syndrome

134

(1)

Idiopathic Hematuria

134

(3)

Glomerulonephritis

137

(1)

Systemic Lupus Erythermatosis

137

(1)

Nephrotic Syndrome

137

(1)

Lithiasis

138

(1)

Therapy

138

(1)

Variants in Relapses

138

(1)

Animal Models

139

(1)

Formation of Spheroplasts in the Rat and Mouse Kidney

139

(1)

Bladder Stones in Rats

139

(1)

Glomerulonephritis in Guinea Pigs

139

(1)

Kidney Medulla as a Protective Environment

139

(1)

Usual Situation

139

(1)

Negating the Protective Hypertonicity of the Medulla

139

(1)

The Kidney as a Site Fostering Reversion

140

(1)

Low Urine Glucose and Latent Infection

140

(2)

Interstitial Cystitis

140

(2)

Nanobacteria

142

(1)

CWD Bacteria as Normal Flora in Urine

142

(1)

Summary

142

(1)

References

143

(4)

Listeria monocytogenes Studies

Introduction

147

(1)

Listeriosis in Children

147

(1)

Listeriosis in Adults

147

(2)

Laboratory Studies on Wall Deficient Variants

149

(1)

Listeria

149

(1)

Listeria in Foods and Hospital Tubing

149

(1)

Pathogenicity of Wall Deficient Variants

150

(1)

Epidemiology of Listeria in Man

150

(1)

Listeria in Livestock

151

(1)

Sensitivity to Bacteriophage

151

(1)

Summary

151

(1)

References

151

(4)

Latency and Persistence

Introduction

155

(3)

Staphylococci

155

(1)

Enteric Bacilli

155

(1)

Listeria

156

(1)

Yersinia

156

(1)

Erysipelothrix rhusiopathiae

157

(1)

Listeria monocytogenes

157

(1)

Glasser's Disease of Swine

157

(1)

Pseudomonas pseudomallei

157

(1)

Rickettsia prowazekii

157

(1)

Actinomyces and Nocardia

157

(1)

Streptococci

158

(1)

Microbial Persistence Related to Intracellular Survival of CWD Forms

158

(1)

Latency in Tuberculosis

159

(1)

Summary

159

(1)

References

159

(4)

Meningitis and Associated Conditions

Introduction

163

(1)

Meningitis Series

163

(1)

Species Wall Deficient in Meningitis

163

(2)

Staphylococci

164

(1)

Streptococci

164

(1)

Pseudomonas

164

(1)

Mycobacteria

165

(1)

Nocardia

165

(1)

Neisseria meningitidis

165

(1)

Postoperative Infections in the Brain

165

(1)

Summary

166

(1)

References

166

(3)

Rheumatic Fever and Erysipelas

Cross-Reacting Antibody

169

(1)

Role of Persisting Cocci and CWD Variants in Antibody Stimulation

169

(4)

Pertinent Organisms in Circulating Blood

169

(1)

Scleroderma

170

(1)

CWD Streptococci in Cardiac Tissues

170

(2)

Variants in Synovial Fluids of Rheumatic Fever Patients

172

(1)

Erysipelas and Recurrent Erysipelas

173

(1)

Summary

174

(1)

References

174

(3)

Joint and Bone Disease

Osteomyelitis

177

(1)

Recurrent Staphylococcal Osteomyelitis

177

(1)

Chronic Staphylococcal Osteomyelitis

177

(1)

Streptococcal Osteomyelitis

177

(1)

Listeria Osteomyelitis

178

(1)

Sclerosing Osteomyelitis

178

(1)

Pyoarthrosis

178

(1)

Nonrheumatoid Arthritis

178

(2)

Gonococcal Arthritis

178

(1)

Clostridial Arthritis

179

(1)

Salmonella Arthritis

179

(1)

Staphylococcal Arthritis

179

(1)

Septic Arthritis in Children

179

(1)

Hemophilus influenzae in Arthritis

180

(1)

Mycobacterial Arthritis

180

(1)

Nocardia asteroides in Canine Arthritis

180

(1)

Streptococcal Arthritis

180

(1)

Rheumatoid Arthritis

180

(4)

Are Classical Streptococci Involved?

180

(1)

Listeria-Like CWD Forms in Blood

180

(1)

Mycoplasma

181

(1)

The Virus in Rheumatoid Arthritis

181

(1)

Role of CWD Propionibacterium acnes in Rheumatoid Arthritis

182

(1)

Resume Rheumatoid Arthritis

183

(1)

Juvenile Rheumatoid Arthritis

184

(1)

Spondylitis

184

(1)

Findings in Veterinary Medicine

184

(1)

Subcutaneous Abscesses with Arthritis

184

(1)

Summary

185

(1)

References

186

(3)

Mycobacterium tuberculosis and the Atypicals

Introduction

189

(1)

In Vitro Growth of CWD Mycobacteria

189

(1)

Spontaneous Variant Growth in Plants

190

(1)

Wall Deficient Mycobacterium tuberculosis in Blood

191

(1)

Enzymatic Reactions of Wall-Deficient Tubercle Bacilli

192

(1)

Wall Deficient Variants in Sputum and Other Specimens

192

(1)

Incidence in Sputum and Significance

192

(1)

Stained Smears of Exudate

193

(1)

Concentration of CWD Colonies

193

(1)

Disease from Only the CWD Stages

193

(1)

Filtrable Stages of Mycobacterium tuberculosis

194

(1)

Mycobacterium scrofulaceum

195

(1)

Mycobacterium avium-intracellulaire (MAC Complex)

195

(1)

Mycobacterium fortuitum

196

(1)

Mycobacterium chelonei

196

(1)

Factors Fostering Mycobacterial Wall Deficiency

197

(1)

``Fragility'' of CWD Mycobacteria

197

(1)

Summary

197

(1)

References

197

(4)

Sarcoidosis

Characteristics of the Disease

201

(1)

Kveim Reaction

201

(1)

Anergy

201

(1)

Evidence Involving a Mycobacterium as Causative Agent

201

(6)

Antibody

201

(1)

Role of Phage?

201

(1)

Acid-Fast Organisms Sighted

202

(1)

Evidence of a Transmissible Pathogen

202

(1)

Culture of an Acid-Fast Organism

203

(1)

Antibody vs. the Sarcoid Isolates

204

(1)

Gel Electrophoresis of Protein Content

204

(1)

Electron Microscopy

204

(2)

Biochemical Reactions

206

(1)

Autofluorescence of Microcolonies

206

(1)

Antimicrobial Sensitivity

206

(1)

New Methods for Tuberculosis and Sarcoid Diagnosis

207

(1)

Finding the Organism in the Blood

207

(1)

Identifying the Organism

207

(1)

Screening Method for TB

207

(1)

Summary

207

(1)

References

208

(3)

Leprosy

Introduction

211

(1)

In Vitro Growth of Mycobacterium leprae

211

(2)

In Vivo Propagation of Mycobacterium leprae

213

(1)

Growth in Mice

213

(1)

Leprosy in an Immunologically Deficient Animal

213

(1)

Growth in the Armadillo

213

(1)

Cell Cultures in Peritoneal Cavities

214

(1)

A Stain for the Classical and Variant Stages of Mycobacterium leprae

214

(1)

Analysis of Immune Complexes

214

(1)

Monoclonal Antibodies

214

(1)

Summary

214

(1)

References

215

(2)

Crohn's Disease and Ulcerative Colitis

Introduction

217

(3)

Is CWD Pseudomonas maltophilia the Agent of CD?

217

(1)

Is the CWD Form of Streptococcus fecalis Involved in These Inflammatory Bowel Diseases?

218

(1)

Findings When Seeking Viruses

218

(1)

Mycobacterial Involvement? Which One?

218

(1)

Does Therapy Suggest Mycobacterial Involvement?

219

(1)

Summary

220

(1)

References

221

(4)

Characteristics of Filtrable Forms

Introduction

225

(1)

Physical Characteristics of Filtrable Forms

225

(1)

Stability and Resistance of the Filtrable Stage

225

(1)

A Nonfiltrable L-Phase Organism

225

(1)

Methods to Increase Filtrability

226

(1)

Treatment to Release Filtrable Units

226

(1)

Inhibitors and Increased Filtrability

226

(1)

In Vivo vs. In Vitro Production of Filtrable Forms

226

(1)

Types of Filters

226

(2)

Collodion Membranes

227

(1)

Membranes of Modified Cellulose

228

(1)

Isolation and/or Reversion of Filtrable Forms

228

(2)

Reversion of Filtrable Forms in Man

228

(1)

Reversion of Filtrates in Laboratory Animals

229

(1)

Isolations of Filtrable States from Man

229

(1)

Filtrable Viruses May Not Be Filtrable Either

230

(1)

Summary

230

(1)

References

230

(5)

Spirochetae

Introduction

235

(1)

Evidence that the Spirochetal Stage is Rare in Syphilis

235

(2)

In Vitro Growth of Nontreponemal Stages

237

(2)

Spinal Fluid as Culture Medium

237

(1)

Tissue Culture

237

(1)

Chicken Embryo

237

(1)

Electron Microscopy

238

(1)

Treponema microdentium

239

(1)

Treponema calligyrum

240

(1)

Yaws (Treponema pertenue)

240

(1)

Lyme Disease

240

(2)

Spirochaeta myelophora in Multiple Sclerosis

242

(1)

An L-Form Laboratory Looks at MS Specimens

243

(1)

Lou Gehrig's Disease (ALS)

243

(1)

Rabbit Spirochetes

243

(1)

Free-Living Spirochetes

244

(1)

Borrelia duttoni of African Relapsing Fever

244

(1)

Borrelia recurrentis of European Relapsing Fever

244

(1)

Borrelia of Fowls

244

(1)

Growth Phases of a Borrelia from Bovine Rumen

244

(1)

Leptospira

245

(1)

Leptospira icterohemorrhagiae

245

(1)

Leptospira pomona

246

(1)

Summary of the Spirochetal Growth Cycle

246

(1)

References

247

(4)

Toxin Formation

Clostridia

251

(2)

Tetanus

251

(1)

Botulism

251

(1)

Gas Gangrene

252

(1)

Corynebacteria

253

(1)

Dermonecrotoxin of Corynebacterium hemolyticum

253

(1)

Diphtheria Bacillus

253

(1)

Toxic Products from Vibrio

253

(1)

Staphylococcal Enterotoxins

253

(1)

Endotoxins

254

(1)

Endotoxicity in Mice Made Hypersensitive by BCG

254

(1)

Shwartzmann Reaction with Microbial L-Forms

254

(1)

Lethality in Chick Embryo

254

(1)

Endotoxins of Hemophilus and Bordetella

254

(1)

Endotoxins of Pseudomonas aeruginosa

255

(1)

Neurotoxins

255

(1)

Summary

255

(1)

References

255

(2)

Fungi

Recognizing Wall Deficiency of Fungi

257

(1)

Huge L-Bodies

257

(1)

Spontaneous Wall Deficient Variants In Vitro

257

(2)

Natural Protoplasts of Histoplasma capsulatum

257

(1)

Spontaneous Wall Deficient Saccharomyces and Candida

257

(1)

Growth of Nutrient-Depleted Candida Cells

258

(1)

Filtration to Demonstrate Spontaneously Wall Deficient Candida

259

(1)

Pleomorphism after Injection into Plants

259

(1)

Fungal Variants in Infections

259

(1)

Mimicking of Tissue Cells by Fungal Wall-Free Variants

260

(1)

Fluorescent Reagents and Polyacrylamide Gel to Identify Fungal Variants

260

(1)

CWD Fungi Formed by Antibiotic, Dyes, or Enzymes

261

(2)

Ramicidin, Mycostatin, Amphotericin B, Crystal Violet, and Brilliant Green

261

(1)

Virulence of CWD Candida

262

(1)

Filtration of Candida Cultures Grown with Inhibitors

262

(1)

Enzymes of the Snail, Helix pomatia

262

(1)

Streptoenzyme from Streptomyces

263

(1)

Enzyme from Mating Gametes

263

(1)

Reversion of Protoplasts

263

(1)

Antibiotic-Dependent Gymnoplasts

263

(1)

Variants as Research Tools

264

(1)

Summary

265

(1)

References

265

(4)

Sensitivity to Antimicrobial Agents

Antibiotic Sensitivities

269

(1)

Sensitivity of CWD Variants from Infections

269

(1)

Sensitivity of In Vitro-Produced Variants

270

(2)

CWD Forms Inhibited by Cell Wall Inhibitors

272

(1)

Bacitracin

272

(1)

Findings with Penicillin

272

(1)

Findings with D-Cycloserine

272

(1)

Reading Antibiotic Sensitivity Tests

272

(1)

CWD Forms Resistant to Agents Lethal for Classical Organisms

273

(1)

CWD Forms Inhibited by Agents Tolerated by the Classical Organism

273

(1)

Revertants May Differ from Parents in Antibiotic Sensitivity

273

(1)

Eradication of CWD Forms when Tissue Cultures are Contaminated

274

(1)

Summary

275

(1)

References

275

(4)

Miscellaneous Disease and Malfunctions

Lung and Bronchial Disease

279

(2)

Historic Study with Streptobacillus moniliformis

279

(1)

Pleurisy and Interstitial Lung Disease by CWD Forms from Uveitis

279

(1)

Pneumonia Complicating a Kidney Graft

280

(1)

Pneumococci Routinely Present in the Blood of Pneumonia Cases

280

(1)

Hemophilus parainfluenzae

281

(1)

L-Phase of Bordetella pertussis

281

(1)

Chronic Bronchitis

281

(1)

Pleurisy and Chronic Empyema

281

(1)

Ocular Disease

281

(2)

Chronic Sinusitis

283

(1)

Tonsillitis

283

(1)

Whipple's Disease

284

(1)

Behcet's Syndrome and Canker Sores (Aphthous Ulcers)

285

(2)

Specific Therapy in Behcet's Disease

287

(1)

Canker Sores (Aphthous Ulcers)

287

(1)

Brucellosis

287

(1)

Neuroendocrine System Damage

288

(1)

Kaposi's Sarcoma

288

(1)

Infections of the Ear

289

(1)

Systemic Lupus Erythermatosis

289

(1)

L-Forms in Dentistry

289

(1)

Human Sterility

289

(1)

Summary

289

(1)

References

290

(5)

Phage

Interactions of CWD Forms with Complete Phage

295

(1)

Receptors for Phage

295

(1)

Metabolism in Spheroplasts after Phage Invasion

295

(1)

Phage Susceptibility and L-Phase Colony Type

295

(1)

Revertability Related to Phage Adsorption

295

(1)

Phage Type and Susceptibility to L-Phase Induction by Antibiotics

296

(1)

Mechanism of Phage Release

296

(1)

Sensitivity to Phage Acquired by Spheroplasting

296

(1)

Comparative Yield of Free Phage from Parent and CWD Stages

296

(1)

General Characteristics of Phage Related to the Ability to Attack CWD Variants

296

(1)

Lysogeny in CWD Forms

296

(3)

Existence and Duration of Lysogeny in CWD Forms

296

(2)

Production of Virulent Phage from Lysogenic CWD Forms

298

(1)

Lysogeny Represses or Fosters Spheroplastic Tendencies

298

(1)

In Vivo Associations of Phage and Host Microbe

299

(1)

Susceptibility of Protoplasts to Phage

299

(1)

Spheroplasts as Hosts for Phage Nucleic Acids

299

(1)

Double-Stranded DNA

299

(1)

Spheroplasts Interpret DNA and Repair Breaks in Nucleic Acids

300

(1)

DNA Replication in Spheroplasts

300

(1)

Phage RNA Reaction with a Psychotropic Drug

300

(1)

Formation of CWD Cells by Phage

300

(1)

Phage Penetrates Classical Organism

300

(1)

CWD Formation after Contact with Inactivated Phage

301

(1)

Phage-Associated Lysins (PAL)

301

(1)

Genetics and Protoplasts

301

(1)

Summary

301

(1)

References

302

(3)

Bacteriocins

Introduction

305

(1)

Relative Susceptibility of CWD Forms to Bacteriocins

305

(1)

CWD Produced by Bacteriocins

306

(1)

Bacteriocin Synthesis by CWD Forms

306

(1)

Are Phage and Colicin Receptors Identical?

306

(2)

Summary

308

(1)

References

308

(3)

Entomology

Sterility from CWD Streptococci

311

(1)

Legacy in Insects of Wall-Deficient Microbes

311

(3)

Housing the Legacy in Colorful Mycetomes

311

(1)

Mycetomes and their Content

311

(1)

Symbionts Essential for Host Life

311

(1)

Variation and Cycling in the Symbionts

312

(1)

Symbionts in the Blood

312

(1)

Fine Structure Studies

312

(1)

Culture of the Bacterial Symbionts

313

(1)

Symbionts May Make N2 Available for Recycling by the Host

314

(1)

Effects of Antibiotics on Symbionts

314

(1)

Microbial Chef for the Leech

314

(1)

Summary

315

(1)

References

315

(2)

Ecology

Introduction

317

(1)

Atypical pH

317

(1)

Temperature

317

(1)

Muralytic Molecules

318

(1)

Chalaropsis B Enzyme (An N-Acetyl Hexosaminidase)

318

(1)

Enzymes from Pseudomonas

318

(1)

Phosphomannanase, An Enzyme from Bacillus circulans

318

(1)

Actinomycete Enzymes

318

(1)

L-Forms Supporting Growth of a Ciliate

318

(1)

Alcohols

318

(1)

Lithium Chloride

319

(1)

Tellurite

319

(1)

Salt Content and Identification of Species

319

(1)

Induction or Fostering by Unidentified Products of Microbial Growth

319

(1)

Antibiotics Produced in Soil

320

(1)

Exposure to Ultraviolet

320

(1)

Bdellovibrios

320

(1)

Alcaligenes L-Forms and Hepatitis Virus

321

(1)

Furunculosis in Fish

321

(1)

Summary

321

(2)

References

323

(2)

Soil Microorganisms

Beef Steak and Peanut Butter

325

(2)

L-Forms and the Tobacco Industry

326

(1)

Pathology of Plants Caused by CWD Bacteria

327

(1)

Tumors in Bean and Carrot Plants

327

(1)

Aster Yellows Disease

327

(1)

Myriad Soil Bacteria Counted by Plating and Electron Microscopy

327

(3)

Pour Plates Compared with Direct Microscopy

327

(1)

Findings by Electron Microscopy

327

(1)

L-Cycle of Azotobacter and Arthrobacter

328

(1)

Gonidia Contrasted with the CWD Cycle

328

(1)

Cores and Crystals in Streptomyces

328

(2)

Summary

330

(1)

References

330

(3)

Microbes and Malignancies

Introduction

333

(1)

Etiology of Hodgkin's Disease

333

(1)

Conclusions

334

(1)

Wall-Deficient Bacteria in Other Malignancies

334

(1)

Diller's Murine Organism

334

(1)

Nazum's Coccus

335

(1)

Classical Organisms which Produce Experimental Malignancies

335

(2)

Bacteria and Fungi of Unknown Pathogenicity Found in Neoplasia

337

(1)

How May a Bacterium Be Carcinogenic?

337

(1)

Altering the Host's Antibody Response

337

(1)

Anergy

337

(1)

Does a Carcinogen-Fostering Bacterium Act as a Helper Virus?

337

(1)

Does a Cancer Bacterium Work by In Vivo Synthesis of a Carcinogenic Compound?

337

(1)

Do Carcinogen-Stimulating Bacteria Carry a Virus of Malignancy?

337

(1)

Do Oncogenic Bacteria Flood the Host with Hormone-Like Substances?

338

(1)

Inherent Difficulties in the Research

338

(1)

Practical Application of Bacteria-in-Cancer Studies

338

(1)

Vaccines for Prophylaxis

338

(1)

Cancer

338

(1)

Antiserum for Therapy

339

(1)

Diagnosis of Cancer by Serological Approach

339

(1)

Current Findings

339

(1)

Summary

339

(1)

References

340

(5)

Artifacts and Contaminants

Introduction

345

(1)

Summary

346

(1)

References

347

(2)

The Placenta

The Placenta and L-Forms

349

(1)

References

350

(1)

Media, Methods, and Stains

Media for Clinical Use

351

(2)

Medium M 70

351

(1)

Rosner's Blood Culture Medium

351

(1)

Domingue's Media for Isolation of CWD Forms from Blood or Urine

352

(1)

MPM Medium

352

(1)

Horse Muscle Infusion Medium

353

(1)

Galactose-Containing Medium

353

(1)

Induction of Variants

353

(4)

Penicillin Induction and Subculture of L-Forms of Staphylococci

353

(1)

Gradient Plates for Induction or to Test Variables

353

(1)

Semidefined Medium for Induction of Staphylococcus aureus L-Forms

354

(1)

Inocula

354

(1)

To Induce L-Forms from Streptococci

354

(1)

Tryptic Digest of Cardiac Muscle

354

(1)

To Induce L-Forms from Salmonella

355

(1)

For Inducing L-Forms of Mycobacteria

355

(1)

Induction of CWD Forms from Nocardia asteroides

355

(1)

Medium to Produce Stable L-Forms of Clostridium perfringens

356

(1)

Medium to Obtain L-Forms of Neisseria meningitidis

356

(1)

Medium for Continued Propagation of CWD Forms

357

(2)

Medium for Maintaining L-Forms of Staphylococcus aureus

358

(1)

Medium for Maintenance of CWD Mycobacteria

358

(1)

Caprice of Culture Media and of CWD Microbes

359

(2)

Age of Media

359

(1)

Water

359

(1)

Agar Source and Concentration

359

(1)

Meat Infusions

360

(1)

Sera

360

(1)

Changes in the Same Medium

360

(1)

eH Requirements

360

(1)

pH Requirements

360

(1)

Erythrocyte Lysate

361

(1)

Osmotic Stabilizers and Adjusting to Normal Osmolality

361

(2)

Solid vs. Liquid Medium

362

(1)

Stabilizing Amines

362

(1)

Inorganic Salts in Stabilizing

362

(1)

Hypertonicity from Carbohydrates

362

(1)

Adaptation of CWD Staphylococcus aureus to Normal Osmolality

362

(1)

Essential Vitamins

363

(1)

Yeast Extracts: Sources, ``Sterilizing,'' and Content

364

(1)

Amino Acid Requirements for Nutrition

364

(1)

Media Components that Inhibit CWD Variants

365

(1)

Reversion Methods

365

(1)

Reversion a la Domingue

365

(1)

Ogawa Medium for Mycobacteria

365

(1)

Xylol Concentrates

366

(1)

Concentrating Organisms from a Broth Culture

366

(1)

Concentrating Borrelia from Lyme, Multiple Sclerosis, and ALS

366

(1)

Storage of the Variants

366

(1)

Pour Plates of Distilled or Deionized Water

366

(1)

Preparations for Electron Microscopy

366

(1)

Stains

367

(5)

Fixation and Washing Smears

367

(1)

Acridine Orange Staining

367

(1)

Procedure for Acridine Orange Stain

367

(1)

Acridine Orange Acid-Fast Stain

367

(1)

Fluorescent Muramidase

368

(1)

Rhodamine B-Labeled Muramidase

368

(1)

Dienes' Stain for Impression Smears

369

(1)

Vital Staining of L-Forms with Chlorazol Black E

370

(1)

Kinyoun's Stain: Intensified for Detection of Acid-Fast CWD Forms

370

(1)

Metanil Yellow Counter Stain

371

(1)

Periodic Acid Pretreatment

371

(1)

Auramine-Rhodamine (AR) Fluorescent Stain for Mycobacteria

371

(1)

Victoria Blue Acid-Fast Stain for Classical and CWD Mycobacteria

371

(1)

Directions for Staining

371

(1)

Composition of Stain, Decolorizer, and Counterstain

371

(1)

The Phenol Phenomenon

372

(1)

Summary

372

(1)

References

372

(7)

Identification

Staining

379

(1)

Temperature Requirements

379

(1)

Biochemical Reactions and Unique Components

379

(3)

Reactions with Analytab Substrates

379

(1)

Cytochrome Oxidase

380

(1)

Lipase

380

(1)

Catalase

381

(1)

DNAase

381

(1)

Agar Hydrolysis

381

(1)

Free Coagulase

382

(1)

Hippuricase

382

(1)

Dye Reductions

382

(1)

Triphenyltetrazolium Chloride (TTC) Reactions

382

(1)

Tellurite Reduction Medium

383

(1)

Hemolysins

383

(1)

CAMP Factor

383

(1)

Pigmentation

384

(1)

M Protein and Hyaluronic Acid from β-Hemolytic Strep

384

(1)

Agglutination and Hemagglutination

384

(1)

Fluorescent Antibody

385

(1)

Fluorescent Lysostaphin

385

(1)

Gel Electrophoresis

386

(2)

Growth Readings Suggest CWD Organisms

388

(1)

Bacteriocins and Bacteriophage

388

(1)

Bacteriocin Production

388

(1)

Phage Lysis

388

(1)

Pathogenesis

388

(1)

Immunoassay and Radioimmunoassay

388

(1)

Nucleic Acid Probes and Hybridization

389

(1)

Gas Chromatography-Mass Spectroscopy

389

(1)

Immunogold Reactions

389

(1)

Antibody Sensitivity Testing

390

(1)

Electron Microscopy with Antibody

390

(1)

Lectins

390

(1)

Summary

391

(1)

References

391

(4)

Appendix

395

(2)

Author Index

397

(8)

Subject Index

405

Lida H. Mattman

Biežāk uzdotie jautājumi par e-grāmatām

Permanent link: https://www.kriso.lv/db/97814822752162e.html

Keywords:

L-form bacteria - Pathogenicity

E-grāmata: Cell Wall Deficient Forms: Stealth Pathogens

DRM restrictions

Kopēšana (kopēt/ievietot):

Drukāšana:

Lietošana:

Konts un iestatījumi

Meklēšana

Meklēt datubāzē

Refine By

Tēmas Ebook Subjects

Izvēlieties iepirkumu grozu