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Chromatographic Techniques in the Forensic Analysis of Designer Drugs [Hardback]

Edited by , Edited by (Lafayette College, Easton, Pennsylvania, USA), Edited by
  • Formāts: Hardback, 478 pages, height x width: 234x156 mm, weight: 952 g, 1 Tables, color; 42 Tables, black and white; 45 Line drawings, color; 82 Line drawings, black and white; 9 Halftones, color; 4 Halftones, black and white
  • Sērija : Chromatographic Science Series
  • Izdošanas datums: 06-Feb-2018
  • Izdevniecība: CRC Press
  • ISBN-10: 1138033286
  • ISBN-13: 9781138033283
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  • Cena: 288,80 €
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  • Formāts: Hardback, 478 pages, height x width: 234x156 mm, weight: 952 g, 1 Tables, color; 42 Tables, black and white; 45 Line drawings, color; 82 Line drawings, black and white; 9 Halftones, color; 4 Halftones, black and white
  • Sērija : Chromatographic Science Series
  • Izdošanas datums: 06-Feb-2018
  • Izdevniecība: CRC Press
  • ISBN-10: 1138033286
  • ISBN-13: 9781138033283
Citas grāmatas par šo tēmu:

There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials. The methods are based on molecular characteristics of the drugs belonging to each individual class of compounds, so it will be clear how the current methods are adaptable to future new drugs that appear in the market.

Preface xiii
About the Editors xv
Contributors xix
SECTION I
Chapter 1 Introduction
3(14)
Teresa Kowalska
Mieczyslaw Sajewicz
Joseph Sherma
Chapter 2 Designer Drugs: Legislating for Tomorrow Through the Use of Class Definitions and Pharmacophore Principles
17(12)
Gregory W. Endres
Travis J. Worst
Jon E. Sprague
Chapter 3 Alternative Legislation with Designer Drugs
29(10)
Dariusz Zuba
Chapter 4 Biological Background of Designer Drugs
39(28)
Lukasz Komsta
Katarzyna Wicha-Komsta
Chapter 5 Liquid Chromatography-Mass Spectrometry in the Analysis of Designer Drugs
67(48)
Beril Anilanmert
Chapter 6 Ambient Plasma Ionization Techniques in Forensic Analysis
115(8)
Przemyslaw Mielczarek
Marek Smoluch
Chapter 7 Application of LC-QTOFMS for the Identification of the Structure of New Psychoactive Substances
123(24)
Karolina Sekuta
Dariusz Zuba
Chapter 8 Rapid Generation of Metabolites by Electrochemical Method
147(10)
Przemyslaw Mielczarek
Marek Smoluch
Chapter 9 Gas Chromatography-Mass Spectrometry in the Analysis of Designer Drugs
157(20)
Bogumita Byrska
Roman Stanaszek
Chapter 10 NMR Spectroscopy in the Analysis of Illegal Drugs
177(22)
Vlatka Vajs
Iris Djordjevic
Ljubodrag Vujisic
Slobodan M. Milosavljevic
Chapter 11 Preparation of Biological Material for Toxicological Analysis
199(12)
Milena Majchrzak
Rafal Celinski
Chapter 12 Discrimination among Designer Drug Isomers by Chromatographic and Spectrometric Methods
211(24)
Piotr Adamowicz
Dariusz Zuba
SECTION II
Chapter 13 Mass Spectrometric Analysis Applied for the Determination of Synthetic Cannabinoids
235(16)
Akira Namera
Takeshi Saito
Yuji Fujita
Chapter 14 Cathinone Derivatives and Their Analysis
251(26)
Milena Majchrzak
Rafal Celinski
Chapter 15 2C Derivatives of Phenylethylamines and Their Analysis
277(28)
Beril Anilanmert
Fatma Cavus Yonar
All Acar Ozdemir
Chapter 16 NBOMe Derivatives of Phenylethylamines and Their Analysis
305(24)
Beril Anilanmert
Fatma Cavus Yonar
Sena Caglar Andac
Chapter 17 Forensic Analysis of Piperazines
329(12)
Chipo Kuleya
Michael D. Cole
Chapter 18 Chromatographic Analysis of Fentanyl and Its Analogs
341(28)
Thomas A. Brettell
Matthew R. Wood
Chapter 19 Modern Techniques for the Identification of Tryptamines
369(22)
Dariusz Zuba
Chapter 20 Toxicological Analysis of New Opioids
391(28)
Karina Sommerfeld-Klatta
Artur Tezyk
Bogna Geppert
Chapter 21 Toxicological Analysis of Designer Benzodiazepines
419(20)
Artur Teiyk
Karina Sommerfeld-Klatta
Bogna Geppert
Chapter 22 Thin-Layer Chromatography in the Analysis of Designer Drugs
439(18)
Joseph Sherma
Teresa Kowalska
Mieczyslaw Sajewicz
Index 457
Teresa Kowalska earned an MSc in chemistry from the former Pedagogical High School in Katowice, Poland, a PhD in physical chemistry from the University of Silesia, Katowice, and a DSc in physical chemistry from The Maria Curie-Sklodowska University in Lublin, Poland. She has authored and coauthored approximately 300 original research and review papers, 16 invited book chapters, and approximately 500 conference papers for scientific conferences. She is also coeditor-in-chief of the international chromatography journal Acta Chromatographica and an editorial board member for several chromatography journals. Her main research interests focus on applications of thin-layer, high-performance liquid and gas chromatography to physicochemical problems.



Mieczyslaw Sajewicz earned an MSc and a PhD in chemistry from the University of Silesia, Katowice, Poland, and a DSc in pharmacy from Collegium Medicum, Jagiellonian University, Kraków, Poland. He has authored and coauthored over 150 original research papers, over 350 conference papers, an encyclopedia entry in Encyclopedia of Chromatography, Second Edition, and two book chapters. He is an editorial board member and coeditor-in-chief of Acta Chromatographica and an editorial board member for the analytical chemistry section of The Scientific World Journal. He is also a member of the Organizing Committee of the annual all-Polish Symposium on Chromatographic Methods of Investigating the Organic Compounds and co-chairman of the Scientific and Organizing Committee of the same event.



Joseph Sherma is professor emeritus of chemistry at Lafayette College, Easton, Pennsylvania. He earned his PhD in analytical chemistry from Rutgers, the State University, New Brunswick, New Jersey, under the supervision of the renowned ion exchange chromatography expert William Rieman III. He taught courses in analytical chemistry for more than 40 years, was head of the Lafayette College Chemistry Department for 12 years, and continues to supervise research students. He has authored, coauthored, edited, or coedited more than 750 publications, including research papers and review articles; approximately 30 invited book chapters; and more than 65 books and U.S. government agency manuals in the areas of analytical chemistry and chromatography. He served for 23 years as editor for residues and trace elements of the Journal of AOAC International and is currently its acquisitions editor. He received the 1995 ACS Award for Research at an Undergraduate Institution sponsored by Research Corporation, and the first 2009 issue of the journal Acta Universitatis Cibiensis, Seria F, Chemia was dedicated in honor of his teaching, research, and publication accomplishments in analytical chemistry and chromatography.