Functional magnetic resonance imaging (FMRI) has become the most widely used method for imaging normal brain function in a relatively short period of time. The use of FMRI in clinically related research has been much slower; however, FMRI is now becoming a valuable tool in the study of many neurological and psychiatric disorders.
This book explains the status of current clinical applications of FMRI in preoperative evaluation, diagnosis and discrimination of pathology, and in understanding recovery, therapeutics and rehabilitation of neurological and psychiatric conditions. Individual chapters cover the use of FMRI in the preoperative assessment of both motor function and language as well as in the assessment of age-related changes in memory. More focused chapters cover the use of FMRI in specific medical conditions including dementia, schizophrenia, depression and anxiety disorders, stroke, Parkinson's disease and multiple sclerosis. The book concludes with a chapter on the role of FMRI in monitoring changes in brain function following exposure to clinical pharmacotherapeutics and experimental drug compounds. This book will be of interest to both novice FMRI researchers and expert FMRI scientists as well as to clinicans in neurology, radiology and psychiatry.
Recenzijas
This is a very useful book for anyone interested in learning the basics of this emerging and important research and clinical tool. Highly recommended. * Doody's Notes *
| Contributors |
|
vii | |
| Preface |
|
ix | |
|
An introduction to clinical functional magnetic resonance imaging of the brain |
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|
1 | (38) |
|
Preoperative assessment: motor function |
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|
39 | (32) |
|
Preoperative assessment: language |
|
|
71 | (44) |
|
Ageing: age-related changes in episodic and working memory |
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|
115 | (34) |
|
Dementia: mild cognitive impairment and Alzheimer's disease |
|
|
149 | (24) |
|
Dementia: visualizing the metabolic changes of early Alzheimer's disease |
|
|
173 | (12) |
|
|
|
185 | (24) |
|
Depression and anxiety disorders |
|
|
209 | (56) |
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|
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265 | (20) |
|
|
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285 | (26) |
|
|
|
311 | (32) |
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fMRI and pharmacology: what role in clinical practice? |
|
|
343 | (38) |
| Index |
|
381 | |
Serge A.R.B Rombouts is Associate Professor of Functional Neuroimaging, Department of Physics and Medical Technology at Vrije University Medical Center, Amsterdam, The Netherlands and is Director of the Leiden Institute for Brain and Cognition (LIBC), Leiden University Medical Center, Leiden, The Netherlands. His primary research interests are functional magnetic resonance neuroimaging and Alzheimer's Disease.
Frederick Barkhof is Professor of Radiology, Vrije University Medical Center, Amsterdam, The Netherlands.
Philip Scheltens is Professor of Cognitive Neurology and Director of the Alzheimer Center at the Vrije Universiteit Medical Center, Amsterdam The Netherlands. His main clinical and research interests are Alzheimer's disease, vascular dementia, frontotemporal dementia, structural and functional magnetic resonance imaging and biomarkers.
