Enormous progress in asthma research has been made in the past 50 years, including a greater understanding of its complex pathogenesis and new and more effective therapies. Consequently, the scientific literature has grown vast and can be difficult to integrate. With contributions from a distinguished panel of world-renowned authors, the Second Edition of Clinical Asthma: Theory and Practice presents a comprehensive study of both the common and the more challenging problems faced by all healthcare personnel who treat patients with asthma.
The book is divided into seven sections, starting with the basics of asthma and ending with a discussion on the approach to asthma worldwide and in the primary care setting. Reflecting a strong clinical emphasis, each chapter begins with a patient case study supported by essential background information on the basic science and clinical decision-making process. This is followed by a discussion of clinical evaluation and management.
The multidisciplinary coverage explores a range of topics including genetics, inflammation, immunology, and the identification of different endotypes. Using a bench-to-bedside approach, the book links basic science to the clinical management of asthma and explores options for improvement. The carefully selected authorship from experts worldwide presents a truly global outlook.
Jonathan A. Bernstein, MD, FAAAAI, FACAAI, FACP, FACCP Professor of Medicine, University of Cincinnati, Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology; Partner Advanced Allergy Services, LLC; Partner Bernstein Clinical Research Center, Cincinnati, Ohio
Mark L. Levy, MBChB (Pret), FRCGPSemi-Retired General Practitioner in London, United Kingdom, with a special interest in asthma. Currently a General Practice Appraiser, London; Member of the Board of Directors and Chair of the Dissemination Working Group of the Global Initiative for Asthma (GINA)
The Basics of Asthma. Understanding Asthma: A Global Epidemiological
Perspective. Immunopathogenesis. Smart Inhalers, Telemedicine and Artificial
Intelligence, and the Future of Asthma Care Worldwide. Endotypes and Asthma.
Diagnosis of Asthma. Guidelines in Asthma. Diagnosis of Asthma in Preschool
Children. Diagnosis of Asthma in Older Children and Adults. United Airways:
Managing Patients with Allergic Rhinitis and Asthma. Asthma Triggers. Viral
Infections in Asthma. Asthma and Allergens. Air Pollutants. Exercise-Induced
Bronchoconstriction. Asthma Education and Outcomes. Asthma Education.
Adherence and Outcomes. Inhaler Devices. Asthma Management and Treatments.
Management of Pediatric Asthma. Management of Adolescent Asthma. Management
of Adult Asthma. Management of Asthma in Older Adults. Severe Acute and
Life-Threatening Asthma in Children. Severe Acute and Chronic
Life-Threatening Asthma in Adults. Learning from Asthma Deaths to Prevent
Attacks. Asthma and Special Populations. Occupational Asthma. Pregnancy and
Asthma. Anxiety and Depression and Asthma. Approach to Asthma Worldwide and
in the Primary Care Setting. Managing Asthma and Allergy: Need for a
Countrywide Approach to Integrating Care. Primary Care Setting and
Integrating Care across Primary/Secondary Care Interface.
Jonathan A. Bernstein, MD, is Professor of Clinical Medicine in the Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology at the University of Cincinnati Medical Center and a partner of Advanced Allergy Services and Bernstein Clinical Research Center. He received his MD from the University of Cincinnati College of Medicine (19811985), completed his residency in Internal Medicine at the Cleveland Clinic Hospital (19851988) and Allergy/Clinical Immunology training at Northwestern University (19881990). He has been a faculty member of UC since 1990. He is the immediate past president of the AAAAI (20222023). He is also a member of the Joint Task Force Guideline committee, the WAO board of directors, President of Interasma, GINA advocacy council, HAEA organization medical advisory board, and WE CU patient advocacy organization. He is a member of the Cincinnati Alpha Lambda Omega society. Dr. Bernstein is a DIA-certified clinical trial investigator and conducting multicenter and physician-initiated clinical therapeutic trials for a number of clinical conditions including asthma, chronic urticaria, hereditary angioedema, atopic dermatitis, and systemic mastocytosis and is considered a key opinion leader in these areas. He was the editor-in-chief of the Journal of Asthma from 2009 to 2022 and is currently on the editorial board for the Journal of Allergy Clinical Immunology; Journal of Allergy in Practice; Annals of Allergy, Asthma & Immunology; and Allergy Proceedings. Dr. Bernstein is the recipient of many awards, including the Distinguished Clinician Awards from the AAAAI and World Allergy Organization (2019). He is currently an author or coauthor of over 510 scientific articles and five books pertaining to asthma, rhinitis, and immunodeficiency. Dr. Bernstein is actively involved with the University of Cincinnati Allergy Fellowship Training Program in the education of fellows and also teaches residents and medical students. Dr. Bernstein has been voted Best Doctor in Cincinnati from 1999 to 2025 by Cincinnati magazine and has been ranked by US News & World Report as being in the top 1% of doctors in his specialty. He is director or codirector for several centers of excellence in Cincinnati, including the WAO center of excellence, the American Initiative for Mast Cell Diseases (AIM), Urticaria Centers of Excellence and Reference (UCARE), Angioedema Centers of Excellence and Reference Care (ACARE), Atopic Dermatitis Centers of Excellence and Reference Care (ADCARE), and Anaphylaxis Centers of Excellence and Reference Care (ANACARE).
Mark L. Levy FRCGP did his medical training in South Africa where he lived until 1977. He has been a United Kingdom (UK) General Practitioner for over 45 years, was a GP trainer for 13 years and was an expert assessor for the National Clinical Assessment service in England for 6 years. He was a voluntary first line responder for the London Ambulance service for 6 years. His interest in respiratory disease started in medical school, followed by six months working in a respiratory intensive care unit in Johannesburg, and has since developed a special interest in asthma. He has authored & co-authored over 180 papers & six books on asthma. He was one of the six founder members, first chairman and past editor of the Primary Care Respiratory Society UK (formerly the GPIAG); currently Editor Emeritus for the Primary Care Respiratory Journal. He was Clinical Lead for the UK National Review of Asthma Deaths (NRAD) (20112014) and has since been expert witness for Coroners in preventable asthma deaths. He was a member of the UK acute asthma guidelines (BTS/SIGN) from 19922017; and is currently an Executive Board member and Chair of the Dissemination Task Group of the annually updated, evidence based, Global Initiative on Asthma (GINA www. ginasthma.org). He was Clinical Lead for the NHS England Data and Digital Transformation program workstream for children and young people and currently is an adviser for the UK All Party Parliamentary Respiratory Group on asthma, COPD and allergy.
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