Clinical Reproductive Immunology provides an up-to-date overview of clinical research in the field of reproductive immunology and pregnancy. With a strong focus on the use of clinical diagnostics to identify immune-related etiologies in pregnancy complications and/or failure, the book also addresses a significant informational gap by providing an overview of clinical data followed by a diagnostic algorithm at the end of each chapter. Every chapter addresses a significant information gap by providing a diagnostic algorithm that will serve to translate the findings from clinical research into a concise, stepwise guide developed with the clinical reproductive specialist in mind. This title builds nicely on the foundational Reproductive Immunology text and serves as a more concise diagnostic reference tool, addressing clinical utility and the significance of related research when developing background sections for manuscripts/literature reviews or for significant sections on grant proposals.
I. Introduction
II. Diagnostic utility of Immune Cells in recurrent implantation failure and early pregnancy loss
1. Decidual immune cells and diagnosis of pregnancy failure
2. Peripheral NK cells and diagnosis of pregnancy failure
3. NK cell KIR and placental HLA haplotype compatibility and pregnancy failure
4. T cell populations and cytokines in diagnosis of pregnancy failure
5. Diagnosis of auto-antibody syndromes in recurrent pregnancy loss (ANA/APA/TPO)
III. Diagnosis of pathogen-associated pregnancy complications and neonatal outcomes
6. Maternal auto-antibodies and fetal neurodevelopment
7. Diagnosis of reproductive tract infections during pregnancy (Bacterial; 1)
8. Diagnosis of reproductive tract infections during pregnancy (Viral; 2)
9. Postnatal screening and diagnosis of congenital infections
10. Endometrial microflora and diagnosis of pregnancy outcomes
IV. Appendix with summary and combination of diagnostic algorithms
Dr. Racicot has over fifteen years of experience working with cell-based assays, in vivo disease models (rodents), and population-based outcome studies related to womens health, immunology, and neurodevelopment. She has significant experience developing cross-functional collaborations with scientific and clinical leaders in the fields of womens health and pediatrics demonstrated by previous and ongoing work as a co-investigator on the nation-wide ECHO program funded by the National Institute of Health. She was the treasurer and chair of the 2019 meeting of the American Society of Reproductive Immunology.
