Comparative Genomics: Volume 2 2007 ed. [Hardback]

This second volume contains the final three of seven sections of tutorials for molecular biologists who are beginning to use comparative genomic analysis tools in a number of different areas. They consider tools for the comparative analysis of domain and gene families; using groups of genes and gene order to analyze genomic evolution; and experimental comparative genomics dealing with such matters as comparing gene copy number across an entire genome, and genome-wide mapping and typing systems for bacterial genomes. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)

Comparative Genomics, Volume 2, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume 2 contains the last three of seven sections. In the second volume, the fifth section describes a number of tools for comparative analysis of domain and gene families. These tools are particularly useful for predicting protein function as well as potential protein-protein interactions. In the sixth section, methods for comparing groups of genes and gene order are discussed, as are several tools for analyzing genome evolution. Finally, the seventh section deals with experimental comparative genomics. This section includes methods for comparing gene copy number across an entire genome, comparative genomic hybridization, SNP analysis, as well as genome-wide mapping and typing systems for bacterial genomes. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 1 is also available from Humana Press.

This volume provides a collection of robust protocols for molecular biologists studying comparative genomics. Each chapter includes detailed instructions for using a particular tool or method and an introduction to the theory behind the technique. Given the tremendous increase in available biosequence data over the past ten years, this volume is timely, comprehensive, and novel.