This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.
Part I: Structure and Biology of the Components of the Extracellular Matrix
1. The Collagen Family of Proteins
2. Elastin: Structure and Biology
3. The Microfibrillar Component of the Elastic Fibers: Morphology and Biochemistry
4. Advances in the Biochemistry of Proteoglycans Part II: Molecular Organization of the Extracellular Matrix
5. Diseases of the Extracellular Matrix: Structural Alterations of Collagen Fibrils in Skin
6. The Molecular Organization of Basement Membrane
7. Vascular Connective Tissue: Normal Biology and Derangement in Human Diseases
8. Cell-Matrix Interactions: Biochemistry of Close and Tight-Focal Adhesive Contacts of Fibroblasts to Extracellular Matrices
9. Matrix Interactions of Cell Surface Proteoglycans
10. Intracellular Degradation as a Modulator of Collagen Production Part III: Pathology of the Extracellular Matrix
11. Disorders Associated with Collagen Biosynthesis: Dermatological Diseases as Prototypes for Collagen Abnormalities
12. Posttranslational Modifications of Collagen and Their Alterations in Heritable Diseases
13. Genetic Diseases of Collagen in Animals
14. The Molecular Pathology of Pulmonary Fibrosis
15. Fibrotic Skin Diseases: Keloids as a Model to Study the Mechanisms of Collagen Deposition in Tissues
16. Pharmacological and Environmental Modulation of Wound Healing
17. Molecular Mechanisms of Glucocorticoid Action on Connective Tissue Metabolism
18. Pathology of the Elastic Fibers
19. Pulmonary Emphysema: From Animal Models to Human Diseases
20. Fibronectin and Disease Processes
21. Vascular and Cutaneous Complications of Diabetes Mellitus: The Role of Nonenzymatic Glucosylation of Collagens
22. Diseases of Glycosaminoglycan and Proteoglycan Metabolism
23. The Role of Connective Tissue Degrading Enzymes in Human Pathology
Jouni Uitto (Harbor-UCLA Med Center, Torrance, California, USA) (Edited by)