This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes and patient management. Authored by leading clinicians, epidemiologists, basic scientists, and clinical trialists, this book captures the latest evidence and best practices for treating patients with AKI.
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Part I Epidemiology and Diagnosis |
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1 Epidemiology, Incidence, Risk Factors, and Outcomes of Acute Kidney Injury |
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3 | (10) |
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2 Definition and Classification of Acute Kidney Injury |
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13 | (10) |
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3 Diagnostic Approach: Differential Diagnosis, Physical Exam, Lab Tests, Imaging, and Novel Biomarkers |
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23 | (22) |
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4 Overview of Pathophysiology of Acute Kidney Injury: Human Evidence, Mechanisms, Pathological Correlations and Biomarkers and Animal Models |
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45 | (24) |
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5 Tubular Physiology in Acute Kidney Injury: Cell Signalling, Injury and Inflammation |
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69 | (26) |
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Part III Clinical Syndromes |
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6 Contrast-Associated Acute Kidney Injury |
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95 | (18) |
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7 Acute Kidney Injury and Liver Disease: Incidence, Pathophysiology, Prevention/Treatment, and Outcomes |
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113 | (20) |
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8 Acute Kidney Injury and Cancer: Incidence, Pathophysiology, Prevention/Treatment, and Outcomes |
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133 | (12) |
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9 Drug-Induced Acute Kidney Injury |
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145 | (20) |
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10 Sepsis and Acute Kidney Injury: Epidemiology, Pathophysiology, Diagnosis, and Management |
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165 | (16) |
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11 Acute Kidney Failure and Minimal Change Disease |
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181 | (14) |
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12 Core Concepts: Post-cardiac Surgery Acute Kidney Injury |
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195 | (8) |
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13 Rare and Overlooked Causes of Acute Kidney Injury |
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203 | (18) |
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14 Acute Kidney Injury in the Tropics: Epidemiology, Presentation, Etiology, Specific Diseases, and Treatment |
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221 | (16) |
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15 Pediatric Acute Kidney Injury: Diagnosis, Epidemiology, and Treatment |
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237 | (10) |
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16 Post-renal Acute Kidney Injury: Epidemiology, Presentation, Pathophysiology, Diagnosis, and Management |
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247 | (10) |
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17 Cardiorenal Acute Kidney Injury: Epidemiology, Presentation, Causes, Pathophysiology, and Treatment |
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257 | (14) |
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18 Perioperative (Non-cardiac) Acute Kidney Injury: Epidemiology, Pathophysiology, Prevention, and Treatment |
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271 | (18) |
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19 Non-dialytic Management of Acute Kidney Injury |
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289 | (20) |
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20 Diuretics in Acute Kidney Injury |
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309 | (8) |
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21 Emerging Therapies: What's on the Horizon? |
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317 | (16) |
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22 Dialytic Therapy of Acute Kidney Injury |
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333 | (10) |
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23 Drug Dosing in Acute Kidney Injury |
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343 | (20) |
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Index |
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363 | |
Ajay K. Singh, MB, MRCP, MBA, Renal Division, Brigham and Womens Hospital, 75 Francis Street, Boston, MA 02115, USA Sushrut S. Waikar, MD, MPH, Renal Division, Brigham and Womens Hospital, 75 Francis Street, Boston, MA 02115, USA Patrick Murray, MDDean of Medicine & Head of SchoolUniversity College Dublin School of Medicine & Medical ScienceDublin, Ireland