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E-grāmata: Corneal Cross-Linking, Second Edition

  • Formāts: 296 pages
  • Izdošanas datums: 03-May-2017
  • Izdevniecība: SLACK Incorporated
  • Valoda: eng
  • ISBN-13: 9781630912123
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  • Bibliotēkām
  • Formāts: 296 pages
  • Izdošanas datums: 03-May-2017
  • Izdevniecība: SLACK Incorporated
  • Valoda: eng
  • ISBN-13: 9781630912123
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"The first of its kind, this comprehensive book, Corneal Collagen Cross-Linking, brings together cross-linking theory, treatment, outcomes, complications and their management. Corneal Collagen Cross-Linking provides a concise yet comprehensive summary ofthe cross-linking (CXL) process, including the basic science foundations, treatment protocols and outcomes, recognition and management of potential complications, and modifications of the standard protocol for special circumstances. Inside the pages of Corneal Collagen Cross-Linking, Dr. Farhad Hafezi and Dr. J. Bradley Randleman include the latest available information on CXL and additional clinical applications, including CXL for infectious keratitis and corneal edema, CXL combined with other treatments for improved refractive outcomes in patients with keratoconus and ectasia after LASIK, and CXL in the pediatric population. Corneal Collagen Cross-Linking is a perfect resource for a wide range of clinicians and researchers, including general ophthalmologists, refractive surgeons, corneal specialists, pediatric ophthalmologists, and optometrists"--Provided by publisher.


The first of its kind, this comprehensive book, Corneal Collagen Cross-Linking, brings together cross-linking theory, treatment, outcomes, complications and their management.

Corneal Collagen Cross-Linking provides a concise yet comprehensive summary of the cross-linking (CXL) process, including the basic science foundations, treatment protocols and outcomes, recognition and management of potential complications, and modifications of the standard protocol for special circumstances.

Inside the pages of Corneal Collagen Cross-Linking, Dr. Farhad Hafezi and Dr. J. Bradley Randleman include the latest available information on CXL and additional clinical applications, including CXL for infectious keratitis and corneal edema, CXL combined with other treatments for improved refractive outcomes in patients with keratoconus and ectasia after LASIK, and CXL in the pediatric population.

Corneal Collagen Cross-Linking is a perfect resource for a wide range of clinicians and researchers, including general ophthalmologists, refractive surgeons, corneal specialists, pediatric ophthalmologists, and optometrists.

Recenzijas

This book is a tour de force, an extremely valuable resource for anyone interested in and performing cornea cross-linking. It is a must-read for cornea specialists and a one-stop source of everything and anything related to cornea cross-linking. -Charles C Lin, MD, Doodys Book Review Service

Dedication v
About the Editors xi
About the Associate Editor xii
Contributing Authors xiii
Foreword xix
Eberhard Spoerl
Theo Seiler
Introduction xxi
Section I Basic Principles of Corneal Biomechanics and Corneal Cross-Linking
1(70)
Chapter 1 History of Corneal Cross-Linking
3(6)
Eberhard Spoerl
Frederik Raiskup
Chapter 2 Introduction to Corneal Biomechanics
9(10)
William J. Dupps Jr
Chapter 3 Fundamental Principles of Corneal Cross-Linking
19(8)
Gregor Wollensak
Chapter 4 Riboflavin, Ultraviolet Light, and the Photochemical Reaction
27(6)
Arie L. Marcovich
Alexander Brandis
Chapter 5 The Role of Oxygen in Corneal Cross-Linking
33(6)
Olivier Richoz
Sabine Kling
Farhad Hafezi
Chapter 6 Cross-Linking Initiated by Other Chromophores and by Multiphoton Excitation
39(4)
Irene Kochevar
Chapter 7 Corneal Cross-Linking Safety Considerations
43(2)
Christina Giannikas Starcic
Leejee H. Suh
Stephen L. Trokel
Chapter 8 Molecular Aspects of Corneal Cross-Linking
45(4)
Rohit Shetty
Natasha Kishore Pahuja
Harsha Nagaraja
Chapter 9 Evaluation and Diagnosis of Keratoconus and Pellucid Marginal Degeneration
49(12)
Marcony R. Santhiago
Yawn S. Rabinowitz
J. Bradley Randleman
Chapter 10 Evaluation and Diagnosis of Postoperative Corneal Ectasia
61(10)
J. Bradley Randleman
Maria A. Woodward
Marcony R. Santhiago
Section II Corneal Cross-Linking for Corneal Ectasias
71(20)
Chapter 11 Corneal Cross-Linking for Progressive Keratoconus
73(8)
Tobias Roller
Stefan Seiler
Theo Seiler
Chapter 12 Corneal Cross-Linking for Postoperative Corneal Ectasia
81(6)
David Tabibian
Farhad Hafezi
Chapter 13 Corneal Cross-Linking for Pellucid Marginal Degeneration
87(4)
Leopoldo Spadea
Roberto Secondi
Section III Corneal Cross-Linking Protocols and Complication Management
91(50)
Chapter 14 The Standard Protocol and Its Parameters
93(6)
Maria A. Woodward
David L. DeMill
Francis W. Price Jr
Marianne O. Price
Chapter 15 Corneal Cross-Linking Using Accelerated Protocols
99(4)
George D. Kymionis
Konstantinos I. Tsoulnaras
Chrysanthi Koutsandrea
Chapter 16 Epithelium-On Protocols: Conceptual/Basic Science
103(8)
Eberhard Spoerl
Suphi Taneri
Chapter 17 Transepithelial Corneal Cross-Linking in Progressive Keratoconus
111(4)
Frederik Raiskup
Chapter 18 Corneal Cross-Linking With Iontophoresis
115(6)
Paolo Vinciguerra
Riccardo Vinciguerra
Fabrizio Camesasca
Vito Romano
Pietro Rosetta
Chapter 19 Cross-Linking Protocols in Thin Corneas
121(6)
Soosan Jacob
Amar Agarwal
Chapter 20 Pediatric Corneal Cross-Linking
127(6)
Joseph Frucht-Pery
Denise Wajnsztajn
Chapter 21 Corneal Cross-Linking Complications and Management
133(8)
Karolinne Maia Rocha
Koray Gumus
J. Bradley Randleman
Section IV Corneal Cross-Linking Imaging and Diagnostic Evaluations
141(38)
Chapter 22 Measuring the Efficacy of Corneal Cross-Linking Using Advanced Corneal Biomechanical Diagnostic Modalities
143(8)
Renato Ambrosio Jr
Marcella Q. Salomao
Cynthia Roberts
Chapter 23 Measuring the Efficacy of Cross-Linking: Clinical Metrics
151(6)
J. Bradley Randleman
Praneetha Thulasi
Chapter 24 Measuring Corneal Cross-Linking Efficacy: Biomechanical Measurement Approach
157(6)
Giuliano Scarcelli
Seok Hyun Yun
J. Bradley Randleman
Chapter 25 Confocal Microscopy in Corneal Cross-Linking
163(6)
Cosimo Mazzotta
Luigi Fontana
Chapter 26 Optical Coherence Tomography Use in Corneal Cross-Linking
169(4)
Sumitra S. Khandelwal
J. Bradley Randleman
Chapter 27 Epithelial Remodeling After Corneal Cross-Linking
173(6)
Karolinne Maia Rocha
Sudeep Dilip Sunthankar
Section V Cross-Linking Plus: Combination Procedures
179(32)
Chapter 28 Corneal Cross-Linking in Combination With Transepithelial Phototherapeutic Keratectomy: Cretan Protocol
181(4)
George D. Kymionis
Michael A. Grentzelos
Chrysanthi Koutsandrea
Chapter 29 Corneal Cross-Linking in Combination With Surface Ablation: Athens Protocol
185(6)
Anastasios John Kanellopoulos
George Asimellis
Chapter 30 Corneal Cross-Linking in Combination With Intracorneal Ring Segment
191(6)
Aylin Kilic
David Touboul
Chapter 31 Corneal Cross-Linking in Combination With Phakic Intraocular Lenses
197(6)
Jose L. Guell
Merce Morral
Emilio J. Segovia
Oscar Gris
Daniel Elies
Felicidad Manero
Chapter 32 Corneal Cross-Linking: Combined Treatment Options
203(4)
Efekan Coskunseven
Onurcan Sahin
Chapter 33 Corneal Cross-Linking as a Primary Refractive Procedure
207(4)
George D. Kymionis
Dimitra M. Portaliou
Michael A. Grentzelos
Chrysanthi Koutsandrea
Section VI Cross-Linking for Infectious Keratitis: PACK-CXL
211(12)
Chapter 34 PACK-CXL
213(6)
Jes Mortensen
Karim Makdoumi
Chapter 35 PACK-CXL for Viral Keratitis and Acanthamoeba Keratitis
219(4)
Francis W. Price Jr
Marianne O. Price
Section VII Other Uses for Cross-Linking
223(10)
Chapter 36 Corneal Cross-Linking for Corneal Stromal Edema
225(4)
Niels Ehlers
Jesper Hjortdal
Chapter 37 Sclera Cross-Linking
229(4)
Brendan Geraghty
Ahmed Elsheikh
Section VIII Current Controversies and Perspectives
233(30)
Chapter 38 Epithelium-On Treatments In Favor
235(8)
Steven E. Wilson
Andre A.M. Torricelli
Opposed
238(5)
Aldo Caporossi
Antonio Villano
Stefano Baiocchi
Orsola Caporossi
Chapter 39 Corneal Cross-Linking Can Impact Limbal Stem Cells In Favor
243(6)
Johnny E. Moore
David Schiroli
C.B. Tara Moore
Opposed
246(3)
Farhad Hafezi
Sabine Kling
Chapter 40 Performing Corneal Cross-Linking After Definitive Signs of Ectasia Progression Are Detected
249(4)
Renato Ambrosio Jr
Rosane de Oliveira Correa
Rozalia Litewski Beildeck
Chapter 41 Prophylactic Cross-Linking Combined With LASIK In Favor
253(4)
Anastasios John Kanellopoulos
George Asimellis
Opposed
255(2)
Theo Seiler
Chapter 42 Summary of Commercially Available Corneal Cross-Linking Units
257(6)
George O. Waring
Susannah L. Brown
Frederik Raiskup
Financial Disclosures 263(4)
Index 267
Farhad Hafezi, MD, PhD, was born in 1967 and grew up in Fribourg, Switzerland. He studied medicine in Fribourg and Berne.Farhad Hafezi fluently speaks German (mother tongue), English, French, Polish, and Farsi. He is married to Nikki Hafezi and has three daughters, Leilah Alina (2008), Lilian Malaya (2010), and Lola Alexandra (2016). Professor Hafezis clinical focus are the cornea and complication management after complicated refractive laser surgery. Being part of the team around Theo Seiler that translated cross-linking from experimental research into the clinical application, he was instrumental in implementing corneal cross-linking technology in ophthalmology. From 2010 to 2014, Farhad Hafezi was Professor and Chairman of the Department of Ophthalmology of the Geneva University Hospitals, Geneva, Switzerland. Currently, Dr. Hafezi holds the following positions: Professor at the Faculty of Medicine, University of Geneva, Switzerland; Clinical Professor of Ophthalmology, Department of Ophthalmology USC Los Angeles, USA; Medical Director, The ELZA Institute, Zürich, Switzerland; Research Group Leader, Center for Applied Biotechnology and Molecular Medicine (CABMM), University of Zürich, Switzerland; and Visiting Professor, Faculty of Medicine, University of Wenzhou, China. As of March 2017, Professor Hafezi has published more than 160 scientific articles, his scientific work has been cited more than 5700 times, his total impact factor is 510, and his h-index is 39. He is an Associate Editor for the Journal of Refractive Surgery and is on the Editorial Boards of TVST, the International Journal of Keratoconus and Ectatic Corneal Disease, Eye and Vision and the Iranian Journal of Ophthalmology. Professor Hafezi is also a member of the Advisory Board of Global ONE, the educational network of the American Academy of Ophthalmology (AAO). Professor Hafezi has received 22 national and international awards and distinctions, both for his scientific work and for the development of new technologies (innovation awards). Awards include, among others, the ARVO Foundation/Carl Camras Translational Research Award (USA) 2014, as well as the highest distinctions in ophthalmology from Switzerland and Belgium. In 2014, Professor Hafezi was voted by peers onto the PowerList, a list of the 100 most influential international personalities in ophthalmology. In April 2016, he was again voted onto the PowerList. For more information, please visit: https://en.wikipedia.org/wiki/Farhad_Hafezi or http://www.elza-institute.com

J. Bradley Randleman, MD, is Professor of Ophthalmology at the Keck School of Medicine of USC and Director of the Cornea & Refractive Surgery Service at the USC Roski Eye Institute in Los Angeles, California. A widely respected cornea specialist, his areas of expertise include: corneal and intraocular refractive surgical procedures including LASIK and premium laser-assisted cataract and IOL surgery, complicated cataract surgery, and the management of corneal ectatic disorders. His primary research focuses on identification and management of corneal ectatic diseases including keratoconus and postoperative ectasia after LASIK, and the avoidance, diagnosis, and management of refractive surgical complications. Dr. Randleman received his BA degree from Columbia College at Columbia University in New York City, his M.D. degree from Texas Tech University School of Medicine in Lubbock, Texas, where he was elected to the Alpha Omega Alpha medical honor society in his junior year, followed by his Ophthalmology residency at Emory University in Atlanta, Georgia. Dr. Randleman joined the Emory faculty and served as Assistant Residency Director for two years while also completing a fellowship in Cornea/External Disease, and Refractive Surgery at Emory University. He served as Director of the Emory Corneal Fellowship program until taking over as Director of the Cornea Service. Dr. Randleman has been awarded the Claus Dohlman Fellow Award, the inaugural Binkhorst Young Ophthalmologist Award from the American Society of Cataract and Refractive Surgery, the Kritzinger Memorial Award, the Inaugural ISRS Recognition Award, the Secretariat Award, Achievement Award, and Senior Achievement Award from the American Academy of Ophthalmology. Dr. Randleman has served as Editor-in-Chief for the Journal of Refractive Surgery since 2011. He has authored more than 120 peer-reviewed publications in leading ophthalmology journals in addition to 30 book chapters on refractive surgery evaluation, corneal cross-linking, and management of complications with IOLs, and has authored two additional textbooks, Refractive Surgery: An Interactive Case-Based Approach (2014), and Intraocular Lens Surgery: Selection, Complications, and Complex Cases.