| Preface |
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xxi | |
| Contributors |
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xxiii | |
| Abbreviations |
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xxv | |
| Introduction |
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Cutaneous Lymphomas---Historical Aspects |
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1 | (6) |
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Unique Features of Cutaneous Lymphomas |
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7 | (4) |
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Cutaneous Lymphoma: A Prototype Neoplasia for Cancer Research |
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11 | (2) |
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13 | (8) |
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13 | (1) |
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Cutaneous T-cell Lymphomas |
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13 | (3) |
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Epidemiologic Factors Influencing Incidence and Mortality Rates |
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16 | (1) |
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Cutaneous B-cell Lymphomas (CBCL) |
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17 | (4) |
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STRUCTURE AND FUNCTION OF THE LYMPHOID SYSTEM |
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21 | (2) |
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Structure and Function of Secondary Lymphoid Tissues |
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23 | (6) |
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27 | (1) |
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Mucosa-Associated Lymphoid Tissues |
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27 | (1) |
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28 | (1) |
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Ontogeny of Lymphoid Cells |
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29 | (8) |
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29 | (1) |
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30 | (1) |
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30 | (1) |
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31 | (1) |
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31 | (1) |
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32 | (1) |
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32 | (1) |
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Monocytes and Macrophages |
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33 | (4) |
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Histo- and Cytomorphology |
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37 | (2) |
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Growth Patterns of Lympho- and Myeloproliferative Infiltrates of the Skin |
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39 | (6) |
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39 | (1) |
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Growth Pattern in Cutaneous Lymphomas |
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40 | (3) |
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Growth Patterns of Myeloproliferative Infiltrates in the Skin |
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43 | (2) |
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DIAGNOSTIC APPROACH TO CUTANEOUS LYMPHOMAS |
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Stepwise Approach to the Diagnosis of Lymphoproliferative Skin Infiltrates and Related Disorders |
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45 | (4) |
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45 | (1) |
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45 | (4) |
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Clinical Staging of Cutaneous Lymphomas |
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49 | (4) |
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Classical Alibert--Bazin Staging |
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49 | (1) |
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49 | (1) |
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50 | (3) |
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Laboratory Investigations |
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53 | (4) |
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53 | (1) |
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Lymph Node and Bone Marrow Biopsies |
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53 | (1) |
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53 | (1) |
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54 | (3) |
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Immunohistochemistry and Phenotypic Features |
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57 | (8) |
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57 | (1) |
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Technical Aspects of Immunophenotyping in Cutaneous Lymphomas |
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57 | (1) |
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A Practical Stepwise Approach to Cutaneous Lymphomas |
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58 | (1) |
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CTCL and Cytotoxic Lymphomas |
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58 | (1) |
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CD30-Positive Lymphoproliferative Diseases |
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59 | (2) |
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CBCL and B-cell Pseudolymphoma |
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61 | (2) |
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Leukemic Infiltrates of the Skin |
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63 | (1) |
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Immunophenotypic Markers as Prognostic Parameters |
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63 | (2) |
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65 | (4) |
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The Identification of a Malignant T-cell Clone by PCR-DGGE |
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66 | (1) |
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Advantages and Limitations of PCR-DGGE |
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67 | (2) |
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Cytogenetic Studies in Cutaneous Lymphomas |
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69 | (4) |
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69 | (1) |
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Genetic Abnormalities in Cutaneous T-cell Lymphomas |
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69 | (1) |
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Genetic Abnormalities in Cutaneous B-cell Lymphomas |
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70 | (1) |
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71 | (2) |
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Functional Profiling by Microarray Technology |
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73 | (6) |
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Types of Microarray Experiments |
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74 | (1) |
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DNA Microarray Experiments |
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75 | (1) |
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Protein-Based Gene Expression Analysis |
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76 | (1) |
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76 | (3) |
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Classification of Nodal Lymphomas in Historical Perspective |
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79 | (4) |
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Revised European--American (REAL) Classification |
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82 | (1) |
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World Health Organization (WHO) Classification of Hematologic Malignancies |
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82 | (1) |
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Classification of Cutaneous Lymphomas in Historical Perspective |
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83 | (8) |
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WHO/EORTC Classification of Cutaneous Lymphomas |
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91 | (4) |
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Prognostic Categorization of Lymphoproliferative Disorders of the Skin: A New and Clinically Oriented Approach |
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95 | (6) |
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95 | (6) |
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CUTANEOUS T-CELL AND NK-CELL LYMPHOMAS |
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101 | (16) |
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101 | (1) |
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101 | (1) |
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101 | (3) |
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104 | (1) |
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105 | (1) |
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106 | (1) |
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107 | (1) |
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107 | (1) |
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Clinical Course and Prognosis |
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107 | (1) |
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108 | (1) |
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109 | (1) |
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Mycosis Fungoides in Childhood and Adolescence |
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109 | (1) |
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109 | (1) |
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109 | (1) |
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109 | (1) |
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109 | (1) |
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109 | (1) |
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Clinical Course and Prognosis |
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110 | (1) |
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110 | (1) |
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110 | (3) |
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113 | (4) |
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113 | (1) |
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113 | (1) |
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113 | (2) |
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115 | (1) |
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115 | (1) |
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Clinical Course and Prognosis |
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115 | (1) |
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116 | (1) |
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Variants and Subtypes of Mycosis Fungoides |
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117 | (22) |
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117 | (6) |
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117 | (1) |
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117 | (1) |
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118 | (1) |
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118 | (1) |
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119 | (1) |
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120 | (1) |
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120 | (1) |
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Clinical Course and Prognosis |
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120 | (1) |
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120 | (1) |
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121 | (2) |
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Syringotropic Cutaneous T-cell Lymphoma |
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123 | (4) |
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123 | (1) |
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123 | (1) |
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123 | (1) |
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123 | (1) |
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124 | (1) |
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125 | (1) |
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125 | (1) |
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Clinical Course and Prognosis |
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125 | (1) |
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125 | (1) |
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125 | (2) |
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Other Variants of Mycosis Fungoides |
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127 | (12) |
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Granulomatous Cutaneous T-cell Lymphomas |
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139 | (14) |
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Granulomatous Variants of CTCL |
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139 | (1) |
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139 | (1) |
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139 | (1) |
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140 | (1) |
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Clinical Course and Prognosis |
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140 | (1) |
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140 | (1) |
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140 | (3) |
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143 | (6) |
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143 | (1) |
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143 | (1) |
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143 | (2) |
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145 | (1) |
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146 | (1) |
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146 | (1) |
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146 | (1) |
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Clinical Course and Prognosis |
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146 | (1) |
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147 | (1) |
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147 | (2) |
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Juvenile Granulomatous Cutaneous T-cell Lymphoma |
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149 | (4) |
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149 | (1) |
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149 | (1) |
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149 | (1) |
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150 | (1) |
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151 | (1) |
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151 | (1) |
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Clinical Course and Prognosis |
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151 | (1) |
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151 | (1) |
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151 | (2) |
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153 | (10) |
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153 | (1) |
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153 | (1) |
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154 | (1) |
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155 | (2) |
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157 | (1) |
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158 | (1) |
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158 | (1) |
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159 | (1) |
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Clinical Course and Prognosis |
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159 | (1) |
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159 | (1) |
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159 | (4) |
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CD30+ T-cell Lymphoproliferative Disorders of the Skin |
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163 | (18) |
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165 | (8) |
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165 | (1) |
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165 | (1) |
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165 | (2) |
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167 | (1) |
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167 | (2) |
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169 | (1) |
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170 | (1) |
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Clinical Course and Prognosis |
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170 | (1) |
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171 | (1) |
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171 | (2) |
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Primary Cutaneous Anaplastic Large Cell Lymphoma |
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173 | (8) |
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Classification and Terminology |
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173 | (1) |
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173 | (1) |
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174 | (1) |
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174 | (1) |
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175 | (1) |
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176 | (1) |
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176 | (1) |
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Clinical Course and Prognosis |
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176 | (1) |
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177 | (1) |
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177 | (4) |
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Subcutaneous Panniculitis-like T-cell Lymphoma |
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181 | (6) |
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181 | (1) |
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181 | (1) |
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181 | (1) |
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181 | (1) |
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182 | (1) |
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183 | (1) |
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Clinical Course and Prognosis |
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184 | (1) |
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184 | (1) |
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184 | (3) |
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Primary Cutaneous Peripheral T-cell Lymphoma, Unspecified |
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187 | (18) |
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187 | (10) |
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188 | (1) |
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CD8+ Cytotoxic Cutaneous T-cell Lymphomas |
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189 | (1) |
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MF-Like Hypo- or Hyperpigmented Form of Cytotoxic CD8+ T-cell Lymphoma |
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189 | (2) |
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Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma |
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191 | (1) |
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Nodular Form of Cytotoxic CD8+ CTCL |
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192 | (3) |
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Cutaneous Gamma/Delta T-cell Lymphoma |
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195 | (1) |
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195 | (1) |
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195 | (1) |
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195 | (1) |
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195 | (1) |
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196 | (1) |
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196 | (1) |
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196 | (1) |
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Clinical Course and Prognosis |
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196 | (1) |
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196 | (1) |
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Primary Cutaneous Peripheral T-cell Lymphoma, Unspecified Noncytotoxic Variants |
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197 | (8) |
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Primary Cutaneous CD4-Positive Small- to Medium-Sized Pleomorphic T-cell Lymphoma |
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197 | (1) |
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197 | (1) |
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197 | (1) |
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197 | (1) |
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198 | (1) |
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198 | (1) |
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199 | (1) |
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199 | (1) |
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Clinical Course and Prognosis |
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199 | (1) |
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199 | (2) |
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Primary Cutaneous Peripheral T-cell Lymphomas, Unspecified, Other Forms |
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201 | (1) |
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201 | (1) |
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201 | (1) |
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202 | (1) |
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202 | (1) |
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202 | (1) |
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202 | (1) |
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Clinical Course and Prognosis |
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202 | (1) |
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202 | (1) |
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203 | (2) |
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Extranodal NK/T-cell Lymphoma, Nasal Type |
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205 | (10) |
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205 | (1) |
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205 | (1) |
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205 | (1) |
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206 | (1) |
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206 | (1) |
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206 | (1) |
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206 | (1) |
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Clinical Course and Prognosis |
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206 | (3) |
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209 | (6) |
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209 | (1) |
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209 | (1) |
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209 | (1) |
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210 | (1) |
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211 | (1) |
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211 | (1) |
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211 | (1) |
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Clinical Course and Prognosis |
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211 | (1) |
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211 | (1) |
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212 | (3) |
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Adult T-cell Leukemia/Lymphoma |
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215 | (6) |
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215 | (1) |
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215 | (1) |
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215 | (1) |
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215 | (2) |
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217 | (1) |
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217 | (1) |
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217 | (1) |
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217 | (1) |
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218 | (3) |
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Cutaneous Manifestations in Other Mature T-cell Neoplasms |
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221 | (10) |
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Angioimmunoblastic T-cell Lymphoma |
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221 | (4) |
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221 | (1) |
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221 | (1) |
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221 | (1) |
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222 | (1) |
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223 | (1) |
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223 | (1) |
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223 | (1) |
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Clinical Course and Prognosis |
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223 | (1) |
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224 | (1) |
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224 | (1) |
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225 | (6) |
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225 | (1) |
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225 | (1) |
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225 | (1) |
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226 | (1) |
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226 | (1) |
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227 | (1) |
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227 | (1) |
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Clinical Course and Prognosis |
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227 | (1) |
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228 | (1) |
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228 | (3) |
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CUTANEOUS B-CELL LYMPHOMAS |
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Primary Cutaneous Marginal Zone B-cell Lymphoma |
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231 | (22) |
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231 | (1) |
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231 | (1) |
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231 | (1) |
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232 | (1) |
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233 | (1) |
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233 | (1) |
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234 | (1) |
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Clinical Course and Prognosis |
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234 | (1) |
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234 | (3) |
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237 | (6) |
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237 | (1) |
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237 | (1) |
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237 | (1) |
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237 | (2) |
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239 | (1) |
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239 | (1) |
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239 | (1) |
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Clinical Course and Prognosis |
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240 | (1) |
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240 | (3) |
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Primary Cutaneous Plasmacytoma (PCP) |
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243 | (6) |
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243 | (1) |
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243 | (1) |
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243 | (2) |
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245 | (1) |
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245 | (1) |
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245 | (1) |
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245 | (1) |
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Clinical Course and Prognosis |
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245 | (1) |
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246 | (1) |
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246 | (3) |
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Cutaneous Follicular Lymphoid Hyperplasia with Monotypic Plasma Cells |
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249 | (4) |
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249 | (1) |
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249 | (1) |
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249 | (1) |
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250 | (1) |
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250 | (1) |
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250 | (1) |
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Clinical Course and Prognosis |
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250 | (1) |
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250 | (1) |
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251 | (2) |
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Primary Cutaneous Follicle Center Lymphoma |
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253 | (6) |
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253 | (1) |
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253 | (1) |
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253 | (1) |
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253 | (2) |
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255 | (1) |
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255 | (1) |
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Clinical Course and Prognosis |
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256 | (1) |
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256 | (1) |
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256 | (3) |
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Primary Cutaneous Diffuse Large B-cell Lymphoma |
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259 | (10) |
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259 | (1) |
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259 | (1) |
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Primary Cutaneous Large B-cell Lymphoma, Leg Type |
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259 | (6) |
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Other Primary Cutaneous Large B-cell Lymphoma |
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263 | (2) |
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Primary Cutaneous Diffuse Large B-cell Lymphomas, Other: T-cell-Rich B-cell Lymphoma |
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265 | (4) |
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265 | (1) |
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265 | (1) |
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265 | (1) |
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266 | (1) |
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266 | (1) |
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267 | (1) |
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267 | (1) |
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Clinical Course and Prognosis |
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268 | (1) |
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268 | (1) |
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268 | (1) |
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Intravascular Large B-cell Lymphoma |
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269 | (6) |
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269 | (1) |
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269 | (1) |
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269 | (1) |
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270 | (1) |
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270 | (1) |
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271 | (1) |
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271 | (1) |
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Clinical Course and Prognosis |
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271 | (1) |
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271 | (1) |
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272 | (3) |
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B-cell Lymphomas with Common Secondary Cutaneous Involvement |
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275 | (18) |
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Lymphomatoid Granulomatosis |
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275 | (4) |
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275 | (1) |
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275 | (1) |
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275 | (1) |
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276 | (1) |
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276 | (1) |
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276 | (1) |
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276 | (1) |
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Clinical Course and Prognosis |
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276 | (1) |
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277 | (2) |
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279 | (6) |
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279 | (1) |
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279 | (1) |
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279 | (1) |
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280 | (1) |
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281 | (1) |
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281 | (1) |
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282 | (1) |
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Clinical Course and Prognosis |
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282 | (1) |
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282 | (1) |
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282 | (3) |
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285 | (4) |
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285 | (1) |
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285 | (1) |
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285 | (1) |
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285 | (1) |
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286 | (1) |
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286 | (1) |
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286 | (1) |
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Clinical Course and Prognosis |
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287 | (1) |
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287 | (2) |
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Waldenstrom Macroglobulinemia |
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289 | (4) |
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289 | (1) |
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289 | (1) |
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289 | (1) |
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290 | (1) |
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290 | (1) |
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290 | (1) |
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291 | (1) |
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Clinical Course and Prognosis |
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291 | (1) |
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291 | (1) |
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291 | (2) |
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Other Forms of Cutaneous B-cell Lymphomas |
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293 | (4) |
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Subcutaneous B-cell Lymphoma |
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293 | (2) |
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293 | (2) |
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Cutaneous B-cell Lymphoma with Signet Ring-Cell Morphology |
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295 | (2) |
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295 | (1) |
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295 | (1) |
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295 | (1) |
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295 | (1) |
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296 | (1) |
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296 | (1) |
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296 | (1) |
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296 | (1) |
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296 | (1) |
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IMMATURE HEMATOPOIETIC MALIGNANCIES |
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297 | (6) |
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297 | (1) |
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297 | (1) |
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297 | (1) |
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297 | (2) |
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299 | (1) |
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299 | (1) |
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300 | (1) |
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Clinical Course and Prognosis |
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300 | (1) |
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301 | (2) |
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Precursor Lymphoblastic Leukemia/Lymphoma |
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303 | (8) |
|
Precursor T-Lymphoblastic Leukemia/Lymphoma |
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303 | (4) |
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303 | (1) |
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303 | (1) |
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303 | (1) |
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304 | (1) |
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304 | (1) |
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304 | (1) |
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304 | (1) |
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Clinical Course and Prognosis |
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304 | (1) |
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|
304 | (3) |
|
Precursor B-Lymphoblastic Leukemia/Lymphoma |
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307 | (4) |
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307 | (1) |
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307 | (1) |
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307 | (1) |
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308 | (1) |
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309 | (1) |
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309 | (1) |
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310 | (1) |
|
Clinical Course and Prognosis |
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|
310 | (1) |
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310 | (1) |
|
Cutaneous Manifestations of Hodgkin Lymphoma |
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311 | (6) |
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311 | (1) |
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Secondary Involvement of the Skin by Systemic Hodgkin Lymphoma |
|
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311 | (1) |
|
Skin Disorders Associated with Systemic Hodgkin Lymphoma |
|
|
312 | (1) |
|
HIV-Associated Hodgkin Lymphoma |
|
|
312 | (1) |
|
Primary Cutaneous Hodgkin Lymphoma |
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|
312 | (5) |
|
Cutaneous Pseudolymphomas |
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|
317 | (34) |
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317 | (1) |
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317 | (2) |
|
Cutaneous T-cell Pseudolymphoma |
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319 | (6) |
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Lymphocytic Infiltration of Jessner-Kanof (Idiopathic Cutaneous T-cell Pseudolymphoma) |
|
|
319 | (2) |
|
Palpable Migratory Arciform Erythema |
|
|
321 | (2) |
|
Lymphomatoid Contact Dermatitis |
|
|
323 | (1) |
|
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|
323 | (1) |
|
Persistent Nodular Arthropod-Bite Reactions |
|
|
323 | (2) |
|
Cutaneous B-cell Pseudolymphoma |
|
|
325 | (6) |
|
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|
Lymphadenosis Benigna Cutis |
|
|
325 | (1) |
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|
325 | (1) |
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326 | (1) |
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327 | (1) |
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328 | (1) |
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328 | (1) |
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|
328 | (3) |
|
Acral Pseudolymphomatous Angiokeratoma of Children |
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331 | (6) |
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331 | (1) |
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331 | (1) |
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331 | (1) |
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332 | (1) |
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333 | (1) |
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|
333 | (1) |
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|
334 | (1) |
|
Clinical Course and Prognosis |
|
|
334 | (1) |
|
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|
334 | (3) |
|
Pseudolymphomatous Folliculitis |
|
|
337 | (4) |
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|
337 | (1) |
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|
337 | (1) |
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|
337 | (1) |
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338 | (1) |
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338 | (1) |
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|
338 | (1) |
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|
338 | (1) |
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|
338 | (3) |
|
Cutaneous Inflammatory Pseudotumor |
|
|
341 | (4) |
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|
341 | (1) |
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|
341 | (2) |
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343 | (1) |
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343 | (1) |
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343 | (1) |
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344 | (1) |
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344 | (1) |
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344 | (1) |
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|
345 | (4) |
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345 | (1) |
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345 | (1) |
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|
345 | (1) |
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|
346 | (1) |
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|
346 | (1) |
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|
346 | (1) |
|
Clinical Course and Prognosis |
|
|
347 | (1) |
|
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|
347 | (1) |
|
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|
348 | (1) |
|
Pseudolymphomatous Infiltrates in the Context of Other Skin Disorders |
|
|
349 | (2) |
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|
351 | (12) |
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|
351 | (1) |
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|
352 | (1) |
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|
352 | (3) |
|
Small Plaque Parapsoriasis |
|
|
355 | (4) |
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|
355 | (1) |
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|
355 | (1) |
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355 | (1) |
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355 | (1) |
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|
356 | (1) |
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|
356 | (1) |
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|
357 | (1) |
|
Clinical Course and Prognosis |
|
|
357 | (1) |
|
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|
357 | (2) |
|
Large Plaque Parapsoriasis With and Without Poikiloderma |
|
|
359 | (4) |
|
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|
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|
Large Patch Type Without Poikiloderma |
|
|
359 | (1) |
|
Large Patch Type With Poikiloderma |
|
|
360 | (3) |
|
Cutaneous T-cell Lymphoproliferative Disorders of Unknown Significance |
|
|
363 | (10) |
|
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|
Papuloerythroderma of Ofuji |
|
|
363 | (4) |
|
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|
363 | (1) |
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|
363 | (1) |
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|
364 | (1) |
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|
364 | (1) |
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|
365 | (1) |
|
Clinical Course and Prognosis |
|
|
365 | (1) |
|
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|
365 | (1) |
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|
365 | (2) |
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|
367 | (6) |
|
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|
368 | (1) |
|
Lichen Planus and Psoriasis |
|
|
368 | (1) |
|
|
|
368 | (2) |
|
Persistent Pigmented Purpuric Dermatitis (PPPD) |
|
|
370 | (1) |
|
Angiolymphoid Hyperplasia with Eosinophilia and Kimura Disease |
|
|
371 | (2) |
|
Skin Involvement in Leukemias |
|
|
373 | (40) |
|
|
|
|
|
373 | (2) |
|
Chronic Lymphocytic Leukemia, B-cell Type (B-CLL) |
|
|
375 | (4) |
|
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|
375 | (1) |
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|
376 | (1) |
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|
377 | (1) |
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|
377 | (2) |
|
Chronic Lymphocytic Leukemia, T-cell Type (T-CLL) |
|
|
379 | (4) |
|
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|
379 | (1) |
|
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|
380 | (1) |
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|
381 | (2) |
|
Chronic Myeloid Leukemia (CML) |
|
|
383 | (4) |
|
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|
|
|
383 | (1) |
|
|
|
384 | (1) |
|
|
|
384 | (3) |
|
Hairy-Cell Leukemia (HCL) |
|
|
387 | (4) |
|
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|
|
|
|
387 | (1) |
|
|
|
388 | (1) |
|
|
|
389 | (2) |
|
Acute Lymphoblastic Leukemia (ALL) |
|
|
391 | (2) |
|
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|
|
|
|
391 | (1) |
|
|
|
391 | (1) |
|
|
|
392 | (1) |
|
Acute (Myelo-) Monocytic Leukemia (AMoL, AMMoL) |
|
|
393 | (6) |
|
|
|
393 | (2) |
|
|
|
395 | (1) |
|
|
|
396 | (3) |
|
Acute Granulocytic (Myeloid) Leukemia (AML) |
|
|
399 | (4) |
|
|
|
|
|
|
|
400 | (1) |
|
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|
400 | (1) |
|
|
|
401 | (2) |
|
Granulocytic Sarcoma (Chloroma) |
|
|
403 | (4) |
|
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|
|
403 | (1) |
|
|
|
404 | (1) |
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|
404 | (3) |
|
Large Granular Lymphocyte Leukemias |
|
|
407 | (4) |
|
|
|
|
|
|
|
Chronic Neutrophilic Leukemia |
|
|
411 | (2) |
|
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|
411 | (1) |
|
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|
411 | (1) |
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|
411 | (1) |
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412 | (1) |
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|
412 | (1) |
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|
412 | (1) |
|
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|
412 | (1) |
|
|
|
412 | (1) |
|
Clinical Course and Prognosis |
|
|
412 | (1) |
|
|
|
412 | (1) |
|
Paraneoplastic Cutaneous Reactions in Leukemia and Lymphomas |
|
|
413 | (6) |
|
|
|
|
|
|
|
|
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|
|
413 | (1) |
|
Classic Paraneoplastic Diseases |
|
|
413 | (1) |
|
Acute Febrile Neutrophilic Dermatosis |
|
|
413 | (2) |
|
|
|
415 | (1) |
|
|
|
416 | (1) |
|
|
|
416 | (1) |
|
|
|
416 | (3) |
|
|
|
419 | (42) |
|
|
|
|
|
|
|
Langerhans Cell Histiocytosis (Histiocytosis X) |
|
|
423 | (8) |
|
|
|
|
|
|
|
|
|
423 | (1) |
|
|
|
423 | (4) |
|
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|
427 | (1) |
|
|
|
428 | (1) |
|
|
|
428 | (1) |
|
|
|
428 | (3) |
|
Indeterminate Cell Histiocytosis |
|
|
431 | (4) |
|
|
|
|
|
|
|
|
|
431 | (1) |
|
|
|
431 | (1) |
|
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|
431 | (1) |
|
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|
432 | (1) |
|
|
|
432 | (1) |
|
|
|
433 | (1) |
|
Clinical Course and Prognosis |
|
|
433 | (1) |
|
|
|
433 | (2) |
|
Sinus Histiocytosis with Massive Lymphadenopathy |
|
|
435 | (6) |
|
|
|
|
|
|
|
|
|
435 | (1) |
|
|
|
435 | (1) |
|
|
|
436 | (1) |
|
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|
437 | (1) |
|
|
|
437 | (1) |
|
Clinical Course and Prognosis |
|
|
437 | (1) |
|
|
|
438 | (1) |
|
|
|
438 | (3) |
|
Multicentric Reticulohistiocytosis (Lipoid Dermatoarthritis) |
|
|
441 | (6) |
|
|
|
|
|
|
|
|
|
441 | (1) |
|
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|
441 | (1) |
|
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|
442 | (1) |
|
|
|
443 | (1) |
|
|
|
443 | (1) |
|
|
|
443 | (1) |
|
Clinical Course and Prognosis |
|
|
444 | (1) |
|
|
|
444 | (3) |
|
|
|
447 | (4) |
|
|
|
|
|
|
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|
|
447 | (1) |
|
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|
447 | (1) |
|
|
|
448 | (1) |
|
|
|
448 | (1) |
|
|
|
449 | (1) |
|
Clinical Course and Prognosis |
|
|
449 | (1) |
|
|
|
450 | (1) |
|
Benign Cephalic Histiocytosis |
|
|
451 | (4) |
|
|
|
|
|
|
|
|
|
451 | (1) |
|
|
|
451 | (1) |
|
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|
451 | (1) |
|
|
|
452 | (1) |
|
|
|
452 | (1) |
|
|
|
453 | (1) |
|
Clinical Course and Prognosis |
|
|
453 | (1) |
|
|
|
453 | (2) |
|
Solitary Reticulohistiocytoma |
|
|
455 | (4) |
|
|
|
|
|
|
|
|
|
455 | (1) |
|
|
|
455 | (1) |
|
|
|
455 | (1) |
|
|
|
456 | (1) |
|
|
|
456 | (1) |
|
Clinical Course and Prognosis |
|
|
457 | (1) |
|
|
|
457 | (2) |
|
Malignant Histiocytic Tumors |
|
|
459 | (2) |
|
|
|
|
|
|
|
|
|
459 | (1) |
|
Malignant Histiocytic Tumors of the Skin |
|
|
459 | (2) |
|
Etiology and Pathogenesis of Cutaneous Lymphomas |
|
|
461 | (14) |
|
|
|
|
|
|
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|
|
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|
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|
|
461 | (1) |
|
|
|
461 | (1) |
|
|
|
462 | (1) |
|
|
|
462 | (2) |
|
Human T-cell Lymphotropic Viruses |
|
|
462 | (1) |
|
Epstein--Barr Virus and Other Herpesviruses |
|
|
463 | (1) |
|
|
|
463 | (1) |
|
|
|
463 | (1) |
|
|
|
464 | (1) |
|
Pathogenetic Models of Cutaneous Lymphomagenesis |
|
|
465 | (10) |
|
|
|
465 | (1) |
|
A Multifactorial Concept of the Pathogenesis of Cutaneous Lymphomas |
|
|
466 | (9) |
|
Therapy of Cutaneous Lymphomas |
|
|
475 | (54) |
|
|
|
475 | (6) |
|
|
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|
|
|
|
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|
|
|
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|
|
479 | (2) |
|
|
|
481 | (16) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Nonaggressive Topical Therapies |
|
|
481 | (4) |
|
Aggressive Topical Therapies |
|
|
485 | (12) |
|
|
|
497 | (14) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Nonaggressive Systemic Therapies |
|
|
497 | (7) |
|
Aggressive Systemic Therapies |
|
|
504 | (7) |
|
|
|
511 | (14) |
|
|
|
|
|
|
|
|
|
Topical Experimental Therapies |
|
|
511 | (3) |
|
Systemic Experimental Therapies |
|
|
514 | (5) |
|
|
|
519 | (6) |
|
Stage-Adjusted Treatment of Cutaneous Lymphomas: The Practical Approach |
|
|
525 | (4) |
|
|
|
|
|
|
|
|
|
|
|
|
|
Cutaneous T-cell Lymphomas (CTCL) |
|
|
525 | (2) |
|
Cutaneous B-cell Lymphomas |
|
|
527 | (2) |
|
|
|
529 | (18) |
|
|
|
|
|
|
|
Prognostic Parameters in Cutaneous Lymphomas |
|
|
529 | (14) |
|
Prognostic Parameters in Cutaneous T-cell Lymphomas |
|
|
529 | (5) |
|
Prognostic Parameters in Cutaneous B-cell Lymphomas |
|
|
534 | (3) |
|
|
|
537 | (6) |
|
Survival Rates in Cutaneous Lymphomas |
|
|
543 | (4) |
|
|
|
|
|
Concepts, Misconceptions, and Controversies in Cutaneous Lymphomas |
|
|
547 | (4) |
|
|
|
Who Was First?: There Will Always Be Somebody ``Before'' |
|
|
547 | (1) |
|
The Infinite Loop of Lymphoma Classification |
|
|
547 | (1) |
|
Using the Same Words Does Not Mean Speaking the Same Language |
|
|
548 | (1) |
|
The Emperor's New Clothes: Seeing Something That Is Not There |
|
|
548 | (1) |
|
Pink and Blue vs. Red and Brown |
|
|
548 | (1) |
|
What Makes the Lymphocyte Angry? |
|
|
549 | (1) |
|
Which Target Do We Really Treat? |
|
|
549 | (2) |
| Index |
|
551 | |
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