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Cytopathology 2nd Revised edition [Mīkstie vāki]

Edited by (Consultant Clinical Cytologist, Cytopathology Department, Ashford and St Peters Hospitals NHS Trust)
  • Formāts: Paperback / softback, 608 pages, height x width x depth: 247x190x27 mm, weight: 1168 g
  • Sērija : Fundamentals of Biomedical Science
  • Izdošanas datums: 28-May-2018
  • Izdevniecība: Oxford University Press
  • ISBN-10: 0198717369
  • ISBN-13: 9780198717362
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  • Formāts: Paperback / softback, 608 pages, height x width x depth: 247x190x27 mm, weight: 1168 g
  • Sērija : Fundamentals of Biomedical Science
  • Izdošanas datums: 28-May-2018
  • Izdevniecība: Oxford University Press
  • ISBN-10: 0198717369
  • ISBN-13: 9780198717362
Citas grāmatas par šo tēmu:
Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.

The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed-from microbiology to cytopathology to transfusion science.

Cytopathology provides a wide-ranging overview of the microscopic study of normal and abnormal cells, showing how current visualization methods are used to study cell structure, and how early detection of abnormal cell pathology can lead to timely clinical interventions.

Recenzijas

Review from previous edition The flow of information is excellent and the text is well-written... a good introductory text for undergraduates with an interest in cytology and for professionals in training. * Dr Lesley Walton, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University * Lucid, logical coverage of material, set out thoughtfully and supported by good illustrations and learning features that make the text student-friendly... a very useful undergraduate cytopathology textbook. * Dr Nicholas Vardaxis, Endeavour College of Natural Health * Clearly written, factual and concise. * Dr Patricia Gadsdon, FIBMS, School of Biological Sciences, Bangor University *

An introduction to the Fundamentals of Biomedical Science series x
Online resources xii
Preface to the first edition xiv
Preface to the second edition xv
Contributors xvi
Abbreviations xix
1 Introduction: a glance at the past, a glimpse of the future
1(11)
Behdad Shambayati
1.1 What is cytology?
2(1)
1.2 The development of cytology
3(4)
3.3 Cytology in the late twentieth and early twenty-first century
7(5)
Summary
10(1)
Further reading
11(1)
2 Preparation techniques
12(33)
Andrew Evered
Behdad Shambayati
2.1 Principles and techniques of specimen collection
13(5)
2.2 The mode of action and effects of cytological fixatives
18(2)
2.3 Preparation techniques
20(10)
2.4 Demonstration techniques
30(15)
Summary
43(1)
Discussion questions
44(1)
3 The cervical screening process
45(24)
John Crossley
Beverley Crossley
3.1 The basic theory of screening programmes
45(8)
3.2 Cervical screening
53(2)
3.3 National Health Service Cervical Screening Programme
55(8)
3.4 Agencies involved in the NHS Cervical Screening Programme
63(6)
Summary
67(1)
Further reading
68(1)
Discussion questions
68(1)
4 Normal cervical cytology
69(42)
Andrew Evered
4.1 Normal anatomy and histology of the female genital system
70(4)
4.2 Physiology of the female genital system
74(7)
4.3 Squamous metaplasia
81(2)
4.4 The cytological failures of normal epithelial cells
83(3)
4.5 Hormonal variations in cervical samples
86(4)
4.6 Non-epithelial cells in cervical samples
90(4)
4.7 Microorganisms in cervical samples
94(5)
4.8 The cytology of inflammation
99(4)
4.9 Iatrogenic changes
103(4)
4.10 Criteria for judging the adequacy of cervical samples
107(4)
Summary
109(1)
Discussion questions
110(1)
5 Abnormal cervical cytology
111(32)
Andrew Evered
5.1 Cervical cancer epidemiology
112(4)
5.2 Squamous neoplasia of the cervix
116(7)
5.3 Glandular neoplasia
123(10)
5.4 Cytological pitfalls
133(4)
5.5 Borderline nuclear changes
137(1)
5.6 Colposcopy and treatment
138(5)
Summary
141(1)
Discussion questions
142(1)
6 Quality issues in cervical screening and cytology
143(14)
John Crossley
Paul Cross
6.1 Quality
144(1)
6.2 Quality of primary cervical screening
145(4)
6.3 Quality of cervical screening triage
149(2)
6.4 Quality measures and quality standards in cervical screening
151(2)
6.5 External quality assessment
153(1)
6.6 Multidisciplinary meetings
154(1)
6.7 Audit
155(2)
Summary
156(1)
Discussion questions
156(1)
7 Diagnostic cytopathology
157(16)
Andrew Evered
7.1 The general principles of diagnostic:, non-cervical cytology
158(2)
7.2 Nomenclature and classification of neoplastic conditions
160(2)
7.3 The mechanisms of tumour genesis and metastasis
162(2)
7.4 Benign processes affecting cell morphology
164(5)
7.5 The role of cancer multidisciplinary teams
169(4)
Summary
172(1)
Discussion questions
172(1)
8 Cytology of urine
173(34)
Behdad Shambayati
8.1 Anatomy and histology
174(1)
8.2 Specimen types
175(4)
8.3 Sample processing
179(1)
8.4 Terminology used in reporting urine samples
180(1)
8.5 Normal voided urine
180(3)
8.6 Benign findings
183(7)
8.7 Urothelial neoplasms
190(4)
8.8 Cytology of urothelial carcinoma
194(6)
8.9 Iatrogenic changes
200(5)
8.10 Ancillary techniques
205(2)
Summary
205(1)
Further reading
205(1)
Discussion questions
206(1)
9 Serous effusions and peritoneal washings
207(54)
Behdad Shambayati
9.1 Anatomy and physiology of serous membranes
208(2)
9.2 Specimen collection and sample processing
210(4)
9.3 Reporting terminology
214(1)
9.4 The cells of effusions
215(8)
9.5 Neoplastic effusions
223(24)
9.6 Peritoneal washings
247(14)
Summary
260(1)
Further reading
260(1)
Discussion questions
260(1)
10 Lower respiratory tract cytology
261(44)
Behdad Shambayati
10.1 Anatomy and normal cytology of the respiratory tract
261(8)
10.2 Specimen collection and sample processing
269(5)
10.3 Reporting terminology
274(1)
10.4 Assessment of sample adequacy
274(1)
10.5 Inflammatory and non-neoplastic cytology
275(2)
10.6 Infections
277(5)
10.7 Lung cancer
282(8)
10.8 Cytology of lung cancer
290(15)
Summary
303(1)
Further reading
303(1)
Discussion questions
304(1)
11 Fine needle aspiration cytology
305(24)
Behdad Shambayati
11.1 Principles and technique of fine needle aspiration
306(5)
11.2 Reporting terminology
311(1)
11.3 Assessment of sample adequacy
312(1)
11.4 Case studies
313(16)
Summary
327(1)
Further reading
327(1)
Discussion questions
327(2)
12 Cytology of the head and neck
329(44)
Paul Cross
Behdad Shambayati
12.1 Salivary glands
330(2)
12.2 Thyroid gland
332(2)
12.3 Parathyroid glands
334(1)
12.4 Lymph nodes
334(2)
12.5 Other tissues of the head and neck
336(1)
12.6 Clinical presentation
337(1)
12.7 Investigation
337(1)
12.8 Salivary gland pathologies
338(22)
12.9 Lymph node pathologies
360(13)
Summary
371(1)
Further reading
372(1)
Discussion questions
372(1)
13 Basic semen analysis
373(26)
Stephen Blackman
Behdad Shambayati
13.1 Spermatozoa production
374(2)
13.2 Semen composition
376(2)
13.3 Reasons for testing patients
378(1)
13.4 Specimen requirements
378(2)
13.5 Laboratory equipment
380(3)
1.3.6 Types of sample
381(2)
13.7 Standard laboratory tests for evaluation of semen
383(10)
13.8 Interpreting the test results
393(6)
Summary
397(1)
Further reading
398(1)
Discussion questions
398(1)
14 Cytology of the biliary tract and pancreas
399(24)
Behdad Shambayati
14.1 Anatomy of the bile ducts, gall bladder, and the pancreas
400(3)
14.2 Sampling techniques
403(4)
14.3 Sample preparation
407(1)
14.4 Normal cytology of the extra-hepatic bile ducts and pancreas
407(3)
14.5 Reporting terminology
410(1)
14.6 Aetiology, symptoms, and treatment of malignancies arising from the biliary tract and the pancreas
411(3)
14.7 Common cytological findings in malignancy
414(9)
Summary
422(1)
Further reading
422(1)
Discussion questions
422(1)
15 Advances in cytopathology
423(49)
Bruno Ping
15.1 Automated cervical screening
424(4)
15.2 Telepathology
428(1)
15.3 The role of HPV testing and the cervical cancer vaccine
428(3)
15.4 Future trends in immunocytochemistry
431(4)
15.5 Flow cytometry
435(1)
15.6 Molecular techniques
436(19)
15.7 Application of molecular techniques in cytopathology
455(17)
Summary
470(1)
Further reading
470(1)
Discussion questions
471(1)
16 Data analysis in cytopathology
472(37)
Andrew Evered
16.1 Types of data in cytology
473(1)
16.2 Presentation of cytology data
473(11)
16.3 Measures of individual and laboratory performance
484(6)
16.4 Procedures for managing cytology performance
490(1)
16.5 Research in cytology
491(18)
Summary
507(1)
Further reading
507(1)
Discussion questions
508(1)
17 Expertise in cytopathology
509(20)
Andrew Evered
17.1 What are the core mental skills in cytology? The three Ds
509(5)
17.2 Bias in cytology
514(3)
17.3 The role of visual memory
517(1)
17.4 The role of selective attention
517(1)
17.5 How do novice cytologists become experts?
518(1)
17.6 Cytology error and its consequences
519(6)
17.7 Beyond the limitations of human perception
525(4)
Summary
526(1)
Further reading
527(1)
Discussion questions
527(2)
Glossary 529(30)
References 559(4)
Index 563
Behdad Shambayati is Consultant Clinical Cytologist at the Cytopathology Department, Ashford and St. Peter's Hospitals Foundation Trust, Chertsey, Surrey