An introduction to the Fundamentals of Biomedical Science series |
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Acknowledgements |
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xiv | |
Contributors |
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xv | |
Abbreviations |
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xvi | |
1 Introduction: a glance at the past, a glimpse of the future |
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1 | (11) |
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2 | (1) |
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1.2 The development of cytology |
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3 | (4) |
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1.3 Cytology in the late twentieth and early twenty-first century |
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7 | (3) |
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10 | (1) |
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11 | (1) |
2 Preparation techniques |
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12 | (34) |
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2.1 Principles and techniques of specimen collection |
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13 | (6) |
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2.2 The mode of action and effects of cytological fixatives |
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19 | (2) |
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2.3 Preparation techniques |
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21 | (11) |
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2.4 Demonstration techniques |
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32 | (12) |
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44 | (1) |
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45 | (1) |
3 The cervical screening process |
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46 | (20) |
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3.1 The basic theory of screening programmes |
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46 | (8) |
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54 | (2) |
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3.3 National Health Service Cervical Screening Programme |
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56 | (2) |
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3.4 Agencies involved in the NHS Cervical Screening Programme |
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58 | (6) |
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64 | (1) |
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65 | (589) |
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654 | |
4 Normal cervical cytology |
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66 | (42) |
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4.1 Normal anatomy and histology of the female genital system |
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67 | (4) |
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4.2 Physiology of the female genital system |
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71 | (7) |
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78 | (2) |
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4.4 The cytological features of normal epithelial cells |
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80 | (3) |
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4.5 Hormonal variations in cervical samples |
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83 | (4) |
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4.6 Non-epithelial cells in cervical samples |
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87 | (4) |
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4.7 Microorganisms in cervical samples |
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91 | (5) |
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4.8 The cytology of inflammation |
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96 | (4) |
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100 | (4) |
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4.10 Criteria for judging the adequacy of cervical samples |
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104 | (2) |
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106 | (1) |
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107 | (1) |
5 Abnormal cervical cytology |
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108 | (29) |
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5.1 Cervical cancer epidemiology |
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109 | (4) |
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5.2 Squamous neoplasia of the cervix |
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113 | (7) |
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120 | (6) |
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126 | (5) |
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5.5 Borderline nuclear changes |
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131 | (1) |
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5.6 Colposcopy and treatment |
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132 | (3) |
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135 | (1) |
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135 | (2) |
6 Quality issues in cervical screening and cytology |
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137 | (24) |
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138 | (1) |
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6.2 Organization of the Cervical Screening Programme |
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139 | (1) |
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6.3 Quality issues in the call and recall office |
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140 | (5) |
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6.4 Quality issues in sample taking and primary care |
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145 | (1) |
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6.5 Quality issues in cytology services |
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146 | (9) |
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6.6 Quality issues in colposcopy services |
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155 | (1) |
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6.7 Quality issues in histology services within the Cervical Screening Programme |
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156 | (1) |
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6.8 Multidisciplinary meetings |
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157 | (1) |
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6.9 Quality assurance reference centre |
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158 | (1) |
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6.10 Cervical cancer audit |
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158 | (1) |
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159 | (1) |
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159 | (1) |
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160 | (1) |
7 Diagnostic cytopathology |
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161 | (16) |
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7.1 The general principles of diagnostic, non-cervical cytology |
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162 | (2) |
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7.2 Nomenclature and classification of neoplastic conditions |
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164 | (2) |
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7.3 The mechanisms of tumour genesis and metastasis |
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166 | (2) |
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7.4 Benign processes affecting cell morphology |
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168 | (5) |
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7.5 The role of cancer multidisciplinary teams |
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173 | (3) |
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176 | (1) |
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176 | (1) |
8 Cytology of urine |
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177 | (32) |
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8.1 Anatomy and histology |
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178 | (1) |
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179 | (4) |
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183 | (1) |
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8.4 Terminology used in reporting urine samples |
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184 | (1) |
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184 | (3) |
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187 | (7) |
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194 | (4) |
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8.8 Cytology of urothelial carcinoma |
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198 | (6) |
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204 | (3) |
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8.10 Ancillary techniques |
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207 | (1) |
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208 | (1) |
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208 | (1) |
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208 | (1) |
9 Serous effusions |
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209 | (38) |
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9.1 Anatomy and physiology of serous membranes |
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210 | (2) |
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9.2 Specimen collection and sample processing |
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212 | (5) |
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9.3 Reporting terminology |
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217 | (1) |
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9.4 The cells of effusions |
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217 | (8) |
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225 | (21) |
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246 | (1) |
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246 | (1) |
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246 | (1) |
10 Lower respiratory tract cytology |
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247 | (44) |
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10.1 Anatomy and normal cytology of the respiratory tract |
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247 | (8) |
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10.2 Specimen collection and sample processing |
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255 | (5) |
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10.3 Reporting terminology |
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260 | (1) |
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10.4 Assessment of sample adequacy |
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260 | (1) |
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10.5 Inflammatory and non-neoplastic cytology |
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261 | (2) |
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263 | (5) |
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268 | (7) |
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10.8 Cytology of lung cancer |
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275 | (14) |
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289 | (1) |
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289 | (1) |
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290 | (1) |
11 Fine needle aspiration cytology |
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291 | (23) |
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11.1 Principles and technique of fine needle aspiration |
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292 | (5) |
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11.2 Reporting terminology |
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297 | (1) |
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11.3 Assessment of sample adequacy |
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298 | (1) |
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299 | (14) |
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313 | (1) |
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313 | (1) |
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313 | (1) |
12 Bask semen analysis |
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314 | (25) |
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12.1 Spermatozoa production |
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315 | (2) |
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317 | (2) |
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12.3 Reasons for testing patients |
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319 | (1) |
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12.4 Specimen requirements |
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319 | (1) |
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12.5 Laboratory equipment |
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320 | (1) |
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321 | (2) |
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12.7 Standard laboratory test for evaluation of semen |
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323 | (10) |
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12.8 Interpreting the test results |
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333 | (4) |
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337 | (1) |
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338 | (1) |
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338 | (1) |
13 Advances in cytopathology |
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339 | (40) |
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13.1 Automated cervical screening |
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340 | (4) |
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344 | (1) |
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13.3 The role of HPV testing and the cervical cancer vaccine |
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344 | (3) |
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13.4 Future trends in immunocytochemistry |
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347 | (4) |
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351 | (1) |
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13.6 Molecular techniques |
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352 | (13) |
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13.7 Application of molecular techniques in cytopathology |
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365 | (11) |
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376 | (1) |
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377 | (1) |
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377 | (2) |
Glossary |
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379 | (24) |
References |
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403 | (4) |
Index |
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407 | |