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Cytopathology [Mīkstie vāki]

3.75/5 (16 ratings by Goodreads)
Edited by (Consultant Clinical Cytologist, Cytopathology Department, Ashford and St Peters Hospitals NHS Trust.)
  • Formāts: Paperback / softback, 448 pages, height x width x depth: 246x190x18 mm, weight: 838 g, 85 colour line drawings and over 400 photos
  • Sērija : Fundamentals of Biomedical Science
  • Izdošanas datums: 17-Feb-2011
  • Izdevniecība: Oxford University Press
  • ISBN-10: 019953392X
  • ISBN-13: 9780199533923
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  • Formāts: Paperback / softback, 448 pages, height x width x depth: 246x190x18 mm, weight: 838 g, 85 colour line drawings and over 400 photos
  • Sērija : Fundamentals of Biomedical Science
  • Izdošanas datums: 17-Feb-2011
  • Izdevniecība: Oxford University Press
  • ISBN-10: 019953392X
  • ISBN-13: 9780199533923
Citas grāmatas par šo tēmu:
The Fundamentals Of Biomedical Science Series is written to reflect the challenges of practising biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis.

-A blend of science theory and biomedical science practice make this series ideal for those seeking both the knowledge and skills to become proficient Biomedical Scientists.

-Content carefully developed to help you demonstrate the competencies required during the study of biomedical science at both undergraduate and postgraduate level.

-Case studies and other examples enrich the text, firmly rooting it in the context of clinical and biomedical practice.

Cytopathology provides a wide-ranging overview of the microscopic study of normal and abnormal cells, showing how current visualization methods are used to study cell structure, and how early detection of abnormal cell pathology can lead to timely clinical interventions.

Cytopathology provides a wide-ranging overview of the microscopic study of normal and abnormal cells, showing how current visualization methods are used to study cell structure, and how early detection of abnormal cell pathology can lead to timely clinical interventions.

`The flow of information is excellent and the text is well written... a good introductory text for undergraduates with an interest in cytology and for professionals in training.'

Dr Lesley Walton, School of Biomolecular Science, Liverpool John Moores University

`Clearly written, factual, and concise.'

Dr Patricia Gadsdon, School of Biological Sciences, Bangor University

Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.

The Fundamentals of Biomedical Science series is written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis.

Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Alongside volumes exploring specific biomedical themes and related laboratory diagnosis, an overarching Biomedical Science Practice volume gives a grounding in the professional and experimental skills with which any Biomedical Scientist must be equipped.

The series
DT Understands the complex roles of Biomedical Scientists in the modern practice of medicine.
DT Understands the development needs of employers and the Profession.
DT Addresses the need for understanding of a range of fundamental sciences in the context of Biomedicine.
DT Places the theoretical aspects of Biomedical Science in their practical context.

Cytopathology provides a broad-ranging overview of the microscopic study of normal and abnormal cells, which embraces the latest imaging and visualization methods to study the structure of cells.

Written with the needs of the biomedical scientist centre-stage, it provides a firm grounding in normal cell structure, and the abnormal features that are indicative of different clinical conditions. It also explains how screening programmes can be used to detect changes early, giving an invaluable opportunity for treatment regimes to be implemented in a timely way.

Crucially, it demonstrates throughout how an understanding of cellular physiology underpins the key investigations carried out by a biomedical scientist to forge a clear link between science and practice.


Online Resource Centre
The Online Resource Centre to accompany Cytopathology features:

For registered adopters of the book:
DT Figures from the book, available to download

For students:
DT An interactive Digital Microscope, encouraging the exploration of tissue samples
DT Self-assessment modules to help you to check and reinforce understanding of the basic science introduced in each volume
DT Video podcasts including interviews with practicing biomedical scientists, and 'in the lab' footage showing biomedical science in practice

Recenzijas

The flow of information is excellent and the text is well-written... a good introductory text for undergraduates with an interest in cytology and for professionals in training. * Dr Lesley Walton, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University * Lucid, logical coverage of material, set out thoughtfully and supported by good illustrations and learning features that make the text student-friendly... a very useful undergraduate cytopathology textbook. * Dr Nicholas Vardaxis, Endeavour College of Natural Health * Clearly written, factual and concise. * Patricia Gadsdon PhD, FIBMS, School of Biological Sciences, Bangor University * I would definitely recommend this book to anyone. * Jermin Simon, student, DeMontfort University *

An introduction to the Fundamentals of Biomedical Science series x
Acknowledgements xiv
Contributors xv
Abbreviations xvi
1 Introduction: a glance at the past, a glimpse of the future 1(11)
Viv Beavers
1.1 What is cytology?
2(1)
1.2 The development of cytology
3(4)
1.3 Cytology in the late twentieth and early twenty-first century
7(3)
Summary
10(1)
Further Reading
11(1)
2 Preparation techniques 12(34)
Allan Wilson
Andrew Evered
2.1 Principles and techniques of specimen collection
13(6)
2.2 The mode of action and effects of cytological fixatives
19(2)
2.3 Preparation techniques
21(11)
2.4 Demonstration techniques
32(12)
Summary
44(1)
Discussion Questions
45(1)
3 The cervical screening process 46(20)
John Crossley
3.1 The basic theory of screening programmes
46(8)
3.2 Cervical screening
54(2)
3.3 National Health Service Cervical Screening Programme
56(2)
3.4 Agencies involved in the NHS Cervical Screening Programme
58(6)
Summary
64(1)
Further Reading
65(589)
Discussion Questions
654
4 Normal cervical cytology 66(42)
Andrew Evered
4.1 Normal anatomy and histology of the female genital system
67(4)
4.2 Physiology of the female genital system
71(7)
4.3 Squamous metaplasia
78(2)
4.4 The cytological features of normal epithelial cells
80(3)
4.5 Hormonal variations in cervical samples
83(4)
4.6 Non-epithelial cells in cervical samples
87(4)
4.7 Microorganisms in cervical samples
91(5)
4.8 The cytology of inflammation
96(4)
4.9 Iatrogenic changes
100(4)
4.10 Criteria for judging the adequacy of cervical samples
104(2)
Summary
106(1)
Discussion Questions
107(1)
5 Abnormal cervical cytology 108(29)
Andrew Evered
5.1 Cervical cancer epidemiology
109(4)
5.2 Squamous neoplasia of the cervix
113(7)
5.3 Glandular neoplasia
120(6)
5.4 Cytological pitfalls
126(5)
5.5 Borderline nuclear changes
131(1)
5.6 Colposcopy and treatment
132(3)
Summary
135(1)
Discussion Questions
135(2)
6 Quality issues in cervical screening and cytology 137(24)
John Crossley
6.1 Quality
138(1)
6.2 Organization of the Cervical Screening Programme
139(1)
6.3 Quality issues in the call and recall office
140(5)
6.4 Quality issues in sample taking and primary care
145(1)
6.5 Quality issues in cytology services
146(9)
6.6 Quality issues in colposcopy services
155(1)
6.7 Quality issues in histology services within the Cervical Screening Programme
156(1)
6.8 Multidisciplinary meetings
157(1)
6.9 Quality assurance reference centre
158(1)
6.10 Cervical cancer audit
158(1)
Summary
159(1)
Further Reading
159(1)
Discussion Questions
160(1)
7 Diagnostic cytopathology 161(16)
Andrew Evered
7.1 The general principles of diagnostic, non-cervical cytology
162(2)
7.2 Nomenclature and classification of neoplastic conditions
164(2)
7.3 The mechanisms of tumour genesis and metastasis
166(2)
7.4 Benign processes affecting cell morphology
168(5)
7.5 The role of cancer multidisciplinary teams
173(3)
Summary
176(1)
Discussion Questions
176(1)
8 Cytology of urine 177(32)
Behdad Shambayati
8.1 Anatomy and histology
178(1)
8.2 Specimen types
179(4)
8.3 Sample processing
183(1)
8.4 Terminology used in reporting urine samples
184(1)
8.5 Normal voided urine
184(3)
8.6 Benign findings
187(7)
8.7 Urothelial neoplasms
194(4)
8.8 Cytology of urothelial carcinoma
198(6)
8.9 latrogenic changes
204(3)
8.10 Ancillary techniques
207(1)
Summary
208(1)
Further Reading
208(1)
Discussion Questions
208(1)
9 Serous effusions 209(38)
Behdad Shambayati
9.1 Anatomy and physiology of serous membranes
210(2)
9.2 Specimen collection and sample processing
212(5)
9.3 Reporting terminology
217(1)
9.4 The cells of effusions
217(8)
9.5 Neoplastic effusions
225(21)
Summary
246(1)
Further Reading
246(1)
Discussion Questions
246(1)
10 Lower respiratory tract cytology 247(44)
Behdad Shambayati
10.1 Anatomy and normal cytology of the respiratory tract
247(8)
10.2 Specimen collection and sample processing
255(5)
10.3 Reporting terminology
260(1)
10.4 Assessment of sample adequacy
260(1)
10.5 Inflammatory and non-neoplastic cytology
261(2)
10.6 Infections
263(5)
10.7 Lung cancer
268(7)
10.8 Cytology of lung cancer
275(14)
Summary
289(1)
Further Reading
289(1)
Discussion Questions
290(1)
11 Fine needle aspiration cytology 291(23)
Behdad Shambayati
11.1 Principles and technique of fine needle aspiration
292(5)
11.2 Reporting terminology
297(1)
11.3 Assessment of sample adequacy
298(1)
11.4 Case studies
299(14)
Summary
313(1)
Further Reading
313(1)
Discussion Questions
313(1)
12 Bask semen analysis 314(25)
Stephen Blackman
Behdad Shambayati
12.1 Spermatozoa production
315(2)
12.2 Semen composition
317(2)
12.3 Reasons for testing patients
319(1)
12.4 Specimen requirements
319(1)
12.5 Laboratory equipment
320(1)
12.6 Types of sample
321(2)
12.7 Standard laboratory test for evaluation of semen
323(10)
12.8 Interpreting the test results
333(4)
Summary
337(1)
Further Reading
338(1)
Discussion Questions
338(1)
13 Advances in cytopathology 339(40)
Margaret Morgan
13.1 Automated cervical screening
340(4)
13.2 Telepathology
344(1)
13.3 The role of HPV testing and the cervical cancer vaccine
344(3)
13.4 Future trends in immunocytochemistry
347(4)
13.5 Flow cytometry
351(1)
13.6 Molecular techniques
352(13)
13.7 Application of molecular techniques in cytopathology
365(11)
Summary
376(1)
Further Reading
377(1)
Discussion Questions
377(2)
Glossary 379(24)
References 403(4)
Index 407
Behdad Shambayati is a Consultant Clinical Cytologist at Ashford and St. Peter's Cytology Department. Behdad was part time lecturer on the IBMS fellowship course at Bromley College of Technology from 1992 to 1996 (when the course ended), and is periodically invited to lecture for the BSc and MSc courses at University of Westminster, NESCOT and University of West of England. He regularly teaches Cytology on courses at Northwick Park Cytology Training School, Welsh Cytology Training School, Sheffield Cytology Training School and South West Cytology Training School. Behdad has been a member of the IBMS Scientific Advisory Panel in cytology since 1999, and is currently their Chief Examiner for cytology.