Continued geographic expansion of dengue viruses and their mosquito vectors has seen the magnitude and frequency of epidemic dengue/dengue hemorrhagic fever (DF/DHF) increase dramatically. Recent exciting research on dengue has resulted in major advances in our understanding of all aspects of the biology of these viruses, and this updated second edition brings together leading research and clinical scientists to review dengue virus biology, epidemiology, entomology, therapeutics, vaccinology and clinical management.
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viii | |
| Preface |
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xiii | |
| Acknowledgement |
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xv | |
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PART I HISTORY AND EPIDEMIOLOGY |
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1 Dengue Viruses: Their Evolution, History and Emergence as a Global Public Health Problem |
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1 | (29) |
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2 Mapping the Epidemiology of Dengue |
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30 | (20) |
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3 Economic and Disease Burden of Dengue |
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50 | (28) |
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4 Surveillance for Dengue |
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78 | (12) |
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5 Dengue Infections in Travelers |
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90 | (9) |
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6 A Review of Transmission Models of Dengue: A Quantitative and Qualitative Analysis of Model Features |
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99 | (16) |
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Isabel Rodriguez-Barraquer |
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7 Clinical Features of Dengue |
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115 | (30) |
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8 Neurological Manifestations of Dengue Virus Infection |
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145 | (23) |
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9 The Southeast Asia Regional Office (WHO) Guidelines for Clinical Management of Dengue Hemorrhagic Fever |
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168 | (16) |
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10 Laboratory Diagnosis of Dengue |
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184 | (30) |
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11 Dengue Pathogenesis: Host Factors |
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214 | (15) |
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12 Dengue Pathogenesis: Viral Factors |
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229 | (20) |
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13 The Acquired Immune Response in Dengue Virus Infection |
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249 | (19) |
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14 Innate Immune Responses to Dengue Infection |
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268 | (16) |
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15 Pathology of Dengue Virus Infection |
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284 | (9) |
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16 Dengue Drug Development |
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293 | (29) |
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17 Taxonomy and Evolutionary Relationships of Flaviviruses |
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322 | (12) |
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18 Molecular Virology of Dengue Virus |
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334 | (31) |
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19 The Structural Biology of Dengue Virus |
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365 | (12) |
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20 The Nonstructural Proteins of Dengue Virus |
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377 | (29) |
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PART IV VIRUS--HOST INTERACTION |
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21 The Interface between Dengue Virus and the Human Host |
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406 | (19) |
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22 Dengue Virus--Mosquito Interactions and Molecular Methods of Vector Control |
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425 | (17) |
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Christopher M. Cirimotich |
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23 Animal Models of Dengue Infection and Disease |
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442 | (13) |
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24 Dengue Vector Bionomics: Why Aedes aegypti is Such a Good Vector |
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455 | (26) |
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25 Surveillance and Control of Urban Dengue Vectors |
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481 | (38) |
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26 Dengue Vector Control: New Approaches |
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519 | (18) |
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27 Biological Control of Dengue and Wolbachia-based Strategies |
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537 | (11) |
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548 | (29) |
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29 Dengue Virus Neutralization and Surrogates of Protection |
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577 | (14) |
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| Index |
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Duane J Gubler is Professor and Program director at Duke-NUS Graduate Medical School, Singapore Ooi Eng Eong and Subhash Vasudevan, Duke-NUS Graduate Medical School, Singapore Jeremy Farrar is Professor of Tropical Medicine, Director of the Oxford University Clinical Research Unit in Viet Nam, Ho Chi Minh City, Vietnam
Biežāk uzdotie jautājumi par e-grāmatām