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Dengue and Zika: Control and Antiviral Treatment Strategies Softcover Reprint of the Original 1st 2018 ed. [Mīkstie vāki]

  • Formāts: Paperback / softback, 375 pages, height x width: 254x178 mm, weight: 1008 g, 70 Illustrations, color; 29 Illustrations, black and white; XIII, 375 p. 99 illus., 70 illus. in color., 1 Paperback / softback
  • Sērija : Advances in Experimental Medicine and Biology 1062
  • Izdošanas datums: 11-Feb-2019
  • Izdevniecība: Springer Verlag, Singapore
  • ISBN-10: 9811342253
  • ISBN-13: 9789811342257
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  • Formāts: Paperback / softback, 375 pages, height x width: 254x178 mm, weight: 1008 g, 70 Illustrations, color; 29 Illustrations, black and white; XIII, 375 p. 99 illus., 70 illus. in color., 1 Paperback / softback
  • Sērija : Advances in Experimental Medicine and Biology 1062
  • Izdošanas datums: 11-Feb-2019
  • Izdevniecība: Springer Verlag, Singapore
  • ISBN-10: 9811342253
  • ISBN-13: 9789811342257
Citas grāmatas par šo tēmu:
This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa.





For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research.





A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the salt in the soup of this book.
Chapter
1. Arboviruses on the rise.
Chapter 2.  Historical perspective
of arboviruses in Mozambique and its implication for current and future
epidemics.
Chapter
3. Reliable serological testing for the diagnosis of
emerging infectious diseases.
Chapter
4. Flaviviral RNA structures and their
role in replication and immunity.
Chapter
5. The Molecular Specificity of
the Human Antibody Response to Dengue Virus Infections.
Chapter
6.
Structures of Zika virus E & NS1: relations with virus infection and host
immune responses.
Chapter 7.  Plugging the leak is dengue a case of
aseptic shock with NS1 at its center.
Chapter
8. Entry & NS1 as drug
targets.
Chapter
9. The dengue virus replication complex: from RNA
replication to protein-protein interactions to evasion of innate immunity.-
Chapter
10. Crystal structure of Zika virus NS2B-NS3 protease.
Chapter
11.
The transactions of NS3 and NS5 in Dengue viral RNA replication.
Chapter
12.
Establishment and application of flavivirus replicons.
Chapter
13.
Strategies towards protease inhibitors for emerging flaviviruses.
Chapter
14. Discovery of potent non-nucleoside inhibitors of dengue viral
RNA-dependent RNA polymerase from fragment screening and structure-guided
design.
Chapter
15. Nuclear cytoplasmic trafficking of dengue non-structural
protein 5 as a target  for antivirals.
Chapter
16. Animal Models for Dengue
and Zika Vaccine Development.
Chapter 17 Understandingthe human T cell
response to dengue virus.
Chapter
18. Regulation and function of NK and T
cells during dengue virus infection and vaccination.
Chapter
19. Structural
insights into the broad-spectrum antiviral target Endoplasmic Reticulum alpha
glucosidase II.
Chapter
20. Mechanisms of antiviral activity of iminosugars
against dengue virus.
Chapter
21. Countering Zika Virus: The USAMRIID
Response.
Chapter 22 Dengue Antiviral Development: A Continuing Journey.-
Chapter 23 An industry perspective on dengue drug discovery and development.-
Chapter
24. The use of Wolbachia by the Eliminate Dengue program to interrupt
transmission of Aedes Aegypti transmitted viruses.
Chapter 25 
Seroepidemiological studies of Arboviruses in Africa.