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Diagnostic Molecular Pathology [Hardback]

  • Formāts: Hardback, 224 pages, height x width: 260x184 mm, weight: 725 g, Illustrated
  • Sērija : Major Problems in Pathology v. 41
  • Izdošanas datums: 07-Apr-2003
  • Izdevniecība: W B Saunders Co Ltd
  • ISBN-10: 0721600476
  • ISBN-13: 9780721600475
Citas grāmatas par šo tēmu:
  • Formāts: Hardback, 224 pages, height x width: 260x184 mm, weight: 725 g, Illustrated
  • Sērija : Major Problems in Pathology v. 41
  • Izdošanas datums: 07-Apr-2003
  • Izdevniecība: W B Saunders Co Ltd
  • ISBN-10: 0721600476
  • ISBN-13: 9780721600475
Citas grāmatas par šo tēmu:
US researchers in pathology and molecular biology help anatomic pathologists understand the significance of the wealth of molecular biological information that has recently become available and shows signs of continuing to increase. They begin by setting out basic molecular biology concepts and methods in a simple format with many illustrations. Then they survey the spectrum of currently used molecular tests in hematopathology, solid tumors, genetics, infectious diseases and identity testing. Annotation (c) Book News, Inc., Portland, OR (booknews.com)

Introduction to Molecular Pathology
1(4)
Debra G.B. Leonard
Genetics
1(1)
Infectious Diseases
1(1)
Leukemias and Lymphomas
2(1)
Solid Tumors
2(1)
Identity Testing
2(1)
Conclusion
3(2)
Basic Principles of Molecular Biology
5(20)
Hanna Rennert
Debra G.B. Leonard
Nucleic Acid Structure and Function
5(1)
DNA
5(2)
RNA
7(2)
Transcription and Translation
9(5)
Gene Expression and Cellular Phenotype
14(2)
Genes, Mutations, and Protein Functions
16(2)
Recombinant DNA Technology
18(7)
Molecular Methods in the Diagnostic Laboratory
25(28)
Hanna Rennert
Debra G.B. Leonard
Polymerase Chain Reaction
25(18)
Direct Hybridization Methods
43(2)
Southern Blot Analysis
45(1)
Northern Blot Analysis
46(1)
Cytogenetics
46(1)
Fluorescence In Situ Hybridization
46(2)
In Situ Hybridization
48(1)
Conclusions
49(4)
Sarcomas
53(24)
Frederic G. Barr
Marc Ladanyi
Introduction and Scope
53(1)
General Biologic Concepts
54(1)
Specific Sarcoma Types
55(12)
Minimal Disease Detection
67(2)
Conclusion
69(8)
Carcinomas
77(36)
Kathy Mangold
Karen Kaul
Overview
77(6)
Molecular Approaches to Testing
83(2)
Molecular Alterations in Solid Tumors
85(15)
Conclusion
100(13)
Leukemias and Lymphomas
113(16)
Margaret L. Gulley
Clonality
113(1)
Chronic Myelogenous Leukemia
113(3)
Acute Promyelocytic Leukemia
116(1)
Gene Translocations in Lymphomas
116(2)
Antigen Receptor Gene Rearrangements
118(6)
Lymphoma-Associated Viruses
124(1)
Conclusions and Future Directions
124(5)
Infectious Diseases
129(14)
Elizabeth R. Unger
Jeannette Guarner
Introduction
129(1)
Identification of Infectious Agents
130(7)
Viral Load Testing
137(1)
Molecular Epidemiology
137(6)
Genetics
143(20)
Jennifer L. Hunt
Karl Volkerding
Genetics in Anatomic Pathology
143(1)
Ethical Considerations in Genetics
143(2)
Genetic Models
145(18)
Identity Testing: Applications of DNA Typing in Anatomic Pathology
163(26)
Vivianna M.D. Van Deerlin
Introduction
163(1)
Historical Perspective
164(1)
Identity Testing by DNA Typing
164(6)
General Technical Issues for the Clinical Laboratory
170(13)
Clinical Applications of DNA Typing Conclusion
183(6)
The Future of Molecular Pathology
189(8)
Debra G.B. Leonard
Science
189(3)
Technology
192(2)
Ethical, Legal, and Social Issues
194(2)
Conclusion
196(1)
Index 197