Musculoskeletal tissues are hard to heal if damaged by disease or trauma. If damaged, they cause pain and hinder regular movements of our bodies. Drug delivery systems that can be used for healing and regenerating these tissues need to be specialized to bear physiological loading on these tissues while helping in controlled release of drug or biomolecules for healing the tissue. This book discusses the pathology of orthopaedic diseases and the requirements of local drug delivery platforms that can help in the treatment of the pathology as well as regeneration of the tissue. The book also discusses in detail the mechanical properties and support that these systems provide to the damaged musculoskeletal tissues and how long-term healing and regeneration is possible. This is an ideal book for students, postdoctoral fellows and faculty at academic universities, and industry professionals who are working on drug delivery, orthopaedic diseases, tissue engineering, and regenerative medicine.
Introduction to Musculoskeletal Tissues & Drug Delivery Systems.- Drug
Delivery Systems for Bone.- Drug Delivery Systems for Cartilage.- Drug
Delivery Systems for Intervertebral Disc.- Drug Delivery Systems for Tendon
and Ligament.- Drug Delivery Systems for Muscles.- Challenges in Clinical
Translation of Musculoskeletal Drug Delivery Systems.- Index.
Dr. Sumit Murab is an Assistant Professor in the School of Biosciences & Bioengineering at Indian Institute of Technology (IIT) Mandi. He also holds secondary appointments in the BioX Centre, Advanced Materials Research Centre (AMRC), Indian Knowledge System and Mental Health Applications Centre (IKSMHA) and Technology Innovation Hub in Human-Computer Interaction (iHub) at IIT Mandi. He is the Coordinator of the Undergraduate Program in Bioengineering and is the Director of the Translational Tissue Engineering Lab at IIT Mandi.
His research interests include orthopaedic tissue engineering, regenerative medicine, in vitro disease models, and biomaterials.
Discusses the existing treatment modalities available for the treatment of diseases
