This book primarily aims to discuss emerging topics in statistical methods and to booster research, education, and training to advance statistical modeling on interval-censored survival data. Commonly collected from public health and biomedical research, among other sources, interval-censored survival data can easily be mistaken for typical right-censored survival data, which can result in erroneous statistical inference due to the complexity of this type of data. The book invites a group of internationally leading researchers to systematically discuss and explore the historical development of the associated methods and their computational implementations, as well as emerging topics related to interval-censored data. It covers a variety of topics, including univariate interval-censored data, multivariate interval-censored data, clustered interval-censored data, competing risk interval-censored data, data with interval-censored covariates, interval-censored data from electric medical records, and misclassified interval-censored data. Researchers, students, and practitioners can directly make use of the state-of-the-art methods covered in the book to tackle their problems in research, education, training and consultation.
- Part I Introduction and Review. - Overview of Historical Developments
in Modeling Interval-Censored Survival Data. - Overview of Recent Advances on
the Analysis of Interval-Censored Failure Time Data. - Predictive Accuracy of
Prediction Model for Interval-Censored Data. - Part II Emerging Topics in
Methodology. - A Practical Guide to Exact Confidence Intervals for a
Distribution of Current Status Data Using the Binomial Approach.
- Accelerated Hazards Model and Its Extensions for Interval-Censored Data.
- Maximum Likelihood Estimation of Semiparametric Regression Models with
Interval-Censored Data. - Use of the INLA Approach for the Analysis of
Interval-Censored Data. - Copula Models and Diagnostics for Multivariate
Interval-Censored Data. - Efficient Estimation of the Additive Risks Model
for Interval-Censored Data. - Part III Emerging Topics in Applications.
- Modeling and Analysis of Chronic Disease Processes Under Intermittent
Observation. - Case-Cohort Studies with Time-Dependent Covariates and
Interval-Censored Outcome. - The BivarIntCensored: An R Package for
Nonparametric Inference of Bivariate Interval-Censored Data. - Joint Modeling
for Longitudinal and Interval-Censored Survival Data: Application to IMPI
Multi-Center HIV/AIDS Clinical Trial. - Regression Analysis with
Interval-Censored Covariates. Application to Liquid Chromatography.
- Misclassification Simulation Extrapolation Procedure for Interval-Censored
Log-Logistic Accelerated Failure Time Model.
Professor (Tony) Jianguo Sun is a Curators Distinguished Professor in the Department of Statistics at the University of Missouri, USA. He is a world-leading researcher in survival data analysis and has in particular been working on the analysis of interval-censored data for over 30 years. He has published over 200 papers and three books and has been invited several times to write review articles on the analysis of interval-censored data. Professor Sun is a Fellow of the American Statistical Association and the Institute of Mathematical Statistics and an Elected Member of the International Statistical Institute.
Professor (Din) Ding-Geng Chen received his Ph.D. in Statistics from the University of Guelph (Canada) in 1995 and is now executive director and professor in Biostatistics at the College of Health Solutions, Arizona State University. He served as a professor in biostatistics at the University of North Carolina-Chapel Hill, a biostatistics professor at the University of Rochester Medical Center, and held the Karl E. Peace endowed eminent scholar chair in biostatistics at the Jiann-Ping Hsu College of Public Health at Georgia Southern University. Dr. Chen is an elected fellow of the American Statistical Association and a senior expert consultant for biopharmaceuticals and government agencies with extensive expertise in clinical trial biostatistics. He has more than 200 scientific publications and has co-authored/co-edited 33 books on clinical trials, survival data, meta-analysis, Monte-Carlo simulation-based statistical modeling, causal inference, big data analytics, and statistical modeling for public health applications. His research has been funded as PI/Co-PI from NIH R01s and other multi-milliondollar state and federal government agencies.
