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Engineering and Application of Pluripotent Stem Cells 2018 ed. [Hardback]

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  • Formāts: Hardback, 228 pages, height x width: 235x155 mm, weight: 4794 g, VII, 228 p., 1 Hardback
  • Sērija : Advances in Biochemical Engineering/Biotechnology 163
  • Izdošanas datums: 12-Mar-2018
  • Izdevniecība: Springer International Publishing AG
  • ISBN-10: 331973590X
  • ISBN-13: 9783319735900
  • Hardback
  • Cena: 270,03 €*
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  • Standarta cena: 317,69 €
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  • Formāts: Hardback, 228 pages, height x width: 235x155 mm, weight: 4794 g, VII, 228 p., 1 Hardback
  • Sērija : Advances in Biochemical Engineering/Biotechnology 163
  • Izdošanas datums: 12-Mar-2018
  • Izdevniecība: Springer International Publishing AG
  • ISBN-10: 331973590X
  • ISBN-13: 9783319735900

?This book reviews the latest biotechnological advances with pluripotent stem cells, exploring their application in tissue engineering and medicinal chemistry. Chapters from expert contributors cover topics such as the production of transgene-free induced pluripotent stem cells (iPSCs), expansion, controlled differentiation and programming of pluripotent stem cells, and their genetic instability. Particular attention is given to the application of the pluripotent stem cells for vascularision of engineered tissue and for drug screening.

This book will appeal to researchers working in regenerative medicine and drug discovery, and to bioengineers and professionals interested in stem cell research.

Nonintegrating Human Somatic Cell Reprogramming Methods.- Scalable
Expansion of Pluripotent Stem Cells.- Scalable Cardiac Differentiation of
Pluripotent Stem Cells Using Specific Growth Factors and Small Molecules.-
 Specific Cell (Re-)Programming: Approaches and Perspectives.- Bioengineered
Cardiac Tissue Based 4 on Human Stem Cells for Clinical Application.- Human
Pluripotent Stem Cells to Engineer Blood Vessels.- Targeted Gene Editing in
Human Pluripotent Stem Cells Using Site-Specific Nucleases.- Acquired Genetic
and Epigenetic Variation in Human Pluripotent Stem Cells.- Requirements for
Using iPSC-Based Cell Models for Assay Development in Drug Discovery.