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E-grāmata: Establishing Precompetitive Collaborations to Stimulate Genomics-Driven Product Development: Workshop Summary

  • Formāts: 90 pages
  • Izdošanas datums: 17-Feb-2011
  • Izdevniecība: National Academies Press
  • Valoda: eng
  • ISBN-13: 9780309161831
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  • Formāts: 90 pages
  • Izdošanas datums: 17-Feb-2011
  • Izdevniecība: National Academies Press
  • Valoda: eng
  • ISBN-13: 9780309161831

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Despite the many basic research discoveries in genetics, relatively few gene-based treatments, drugs, or preventative measures have been developed. One way to bridge this gap may be for industry, academia, and government to develop partnerships that share resources while distributing risk. However, intellectual property protections and other barriers can inhibit collaborative efforts. The Institute of Medicine held a workshop on July 22, 2010, to explore these issues and develop solutions.

Table of Contents



Front Matter 1 Introduction 2 A Lesson About Precompetitive Collaboration 3 Requisites for Successful Precompetitive Collaboration 4 Frameworks for Collaboration 5 The Use of Biospecimens in Precompetitive Collaborations 6 Ethical Challenges in the Use of Biospecimens 7 Toward Developing a Cultural, Legal, and Behavioral Framework for Precompetitive Collaboration References Appendix A: Workshop Agenda Appendix B: Speaker Biographical Sketches
Abbreviations and Acronyms xv
1 Introduction
1(8)
Expanded Use of Precompetitive Collaborations
3(1)
Identifying New Approaches to Precompetitive Collaboration
3(3)
The Potential for Precompetitive Sharing of Biobanked Specimens
6(3)
2 A Lesson About Precompetitive Collaboration
9(4)
The SEMATECH Experience
9(2)
Lessons from SEMATECH
11(2)
3 Requisites for Successful Precompetitive Collaboration
13(8)
Requisites from the Pharmaceutical Industry
13(2)
Requisites from Diagnostic Companies
15(1)
Requisites from Academia
16(5)
4 Frameworks for Collaboration
21(10)
Public-Private Partnerships with NIH or Government
21(3)
Advancing Technological Achievements Through Collaboration
24(2)
Open Access Partnerships
26(2)
Access to Large-Scale Data Networks
28(3)
5 The Use of Biospecimens in Precompetitive Collaborations
31(14)
Standards for Biospecimen Quality
32(3)
Linking Health Outcomes Data to Biorepository Samples
35(3)
Sustaining Access to Biospecimens
38(2)
Creating a National Virtual Biospecimen Bank
40(2)
Clinical and Genetic Data Access in the Pharmaceutical Industry
42(3)
6 Ethical Challenges in The Use of Biospecimens
45(4)
Discussion
47(2)
7 Toward Developing a Cultural, Legal, and Behavioral Framework for Precompetitive Collaboration
49(6)
Facing the Problems
49(2)
Drawing the Line Between Precompetitive and Competitive Efforts
51(1)
Moving Forward
52(1)
Sharing Biospecimens and Data
52(1)
Final Thoughts
53(2)
REFERENCES
55(2)
APPENDIXES
A Workshop Agenda
57(6)
B Speaker Biographical Sketches
63