Series Preface |
|
ix | |
Preface |
|
xi | |
Editors |
|
xv | |
Contributors |
|
xvii | |
1 Introduction to Functional Foods and Nutraceuticals |
|
1 | (32) |
|
|
|
|
2 | (1) |
|
|
2 | (2) |
|
1.2.1 The concept of functional foods |
|
|
2 | (1) |
|
1.2.2 World market for functional foods |
|
|
3 | (1) |
|
|
4 | (2) |
|
1.3.1 The concept of nutraceuticals |
|
|
4 | (1) |
|
1.3.2 Market scenario for nutraceuticals |
|
|
5 | (1) |
|
1.3.3 Safety aspects of nutraceuticals |
|
|
6 | (1) |
|
1.4 Sources of functional foods |
|
|
6 | (5) |
|
|
6 | (6) |
|
|
6 | (1) |
|
|
7 | (1) |
|
|
7 | (1) |
|
|
7 | (2) |
|
|
9 | (1) |
|
|
9 | (1) |
|
|
9 | (1) |
|
|
10 | (1) |
|
|
10 | (1) |
|
|
10 | (1) |
|
1.4.1.11 Breakfast cereals |
|
|
10 | (1) |
|
1.5 Dairy-based functional foods |
|
|
11 | (1) |
|
|
12 | (1) |
|
|
12 | (1) |
|
1.8 Confectionery-based functional foods |
|
|
12 | (1) |
|
|
12 | (1) |
|
|
12 | (1) |
|
|
13 | (1) |
|
1.9 Beverage-based functional foods |
|
|
13 | (1) |
|
|
13 | (1) |
|
1.10 Legume-based functional foods |
|
|
13 | (1) |
|
|
13 | (1) |
|
1.11 Fruit- and vegetable-based functional foods |
|
|
14 | (5) |
|
|
14 | (1) |
|
|
15 | (1) |
|
1.11.3 Broccoli and other cruciferous vegetables |
|
|
15 | (2) |
|
|
17 | (1) |
|
|
17 | (1) |
|
1.11.6 Red wine and grapes |
|
|
17 | (1) |
|
|
18 | (1) |
|
|
18 | (1) |
|
1.11.9 Cordyceps mushrooms |
|
|
18 | (1) |
|
|
19 | (1) |
|
1.12 Animal-Based functional foods |
|
|
19 | (3) |
|
|
19 | (2) |
|
|
21 | (1) |
|
1.12.3 Eggs enriched with PUFAs |
|
|
21 | (1) |
|
|
22 | (1) |
|
|
22 | (11) |
2 Flavoring of Pediatric Nutritional Supplements and Pediatric Compliance: A Perspective |
|
33 | (18) |
|
|
|
|
|
33 | (2) |
|
2.2 Child nourishment problems, related diseases, and nutritional supplementation solutions |
|
|
35 | (1) |
|
2.3 Nutritional deficiencies that affect infants and children |
|
|
36 | (2) |
|
2.3.1 Vitamin D deficiency |
|
|
36 | (1) |
|
|
36 | (1) |
|
|
37 | (1) |
|
2.3.4 Vitamin A deficiency |
|
|
37 | (1) |
|
2.4 Effect of flavor on supplement intake and consumption in children |
|
|
38 | (1) |
|
2.5 Flavoring agents: Types and applications |
|
|
39 | (2) |
|
2.6 Regulatory consideration of pediatric flavoring agents |
|
|
41 | (3) |
|
|
44 | (2) |
|
2.7.1 Advanced demasking of iron supplements |
|
|
44 | (1) |
|
2.7.2 Masking the fishy odor and taste of omega 3 fatty acids |
|
|
45 | (1) |
|
2.7.3 Masking the taste of calcium and magnesium supplements |
|
|
45 | (1) |
|
2.8 Discussion and conclusion |
|
|
46 | (2) |
|
|
48 | (3) |
3 Flavors in Probiotics and Prebiotics |
|
51 | (24) |
|
|
|
|
|
51 | (4) |
|
3.2 Flavors in probiotics and prebiotics |
|
|
55 | (1) |
|
3.3 Flavor characteristics of probiotic/prebiotic products |
|
|
56 | (9) |
|
3.3.1 Fermented dairy products |
|
|
56 | (7) |
|
|
56 | (2) |
|
|
58 | (1) |
|
|
59 | (2) |
|
|
61 | (1) |
|
3.3.1.5 Fermented milk drinks |
|
|
61 | (2) |
|
3.3.1.6 Miscellaneous dairy-based probiotic beverages |
|
|
63 | (1) |
|
3.3.2 Fermented nondairy probiotic beverages |
|
|
63 | (2) |
|
3.4 Flavor/aroma defects in probiotics and prebiotics |
|
|
65 | (1) |
|
3.5 Testing of flavor/sensory defects |
|
|
66 | (2) |
|
|
68 | (1) |
|
|
68 | (7) |
4 Natural Ingredients/Botanical Extracts for the Nutraceutical Industry |
|
75 | (48) |
|
|
|
|
|
|
|
|
|
|
76 | (1) |
|
4.2 The global nutraceutical industry |
|
|
77 | (1) |
|
4.3 Nutraceutical markets for plant extracts |
|
|
77 | (1) |
|
4.3.1 The European market |
|
|
77 | (1) |
|
|
78 | (1) |
|
4.4 Classification of nutraceuticals based on natural sources |
|
|
78 | (12) |
|
|
78 | (2) |
|
|
80 | (2) |
|
|
80 | (1) |
|
|
81 | (1) |
|
|
81 | (1) |
|
|
82 | (1) |
|
|
82 | (2) |
|
|
84 | (6) |
|
|
84 | (4) |
|
|
88 | (1) |
|
|
88 | (1) |
|
|
88 | (1) |
|
4.4.4.5 Phenolic compounds and prebiotics |
|
|
89 | (1) |
|
4.4.4.6 Enzymes, vitamins, and minerals |
|
|
89 | (1) |
|
4.5 Methods for extracting herbal products |
|
|
90 | (16) |
|
|
90 | (1) |
|
|
91 | (2) |
|
4.5.2.1 Modifications made to the percolation process |
|
|
92 | (1) |
|
4.5.2.2 Types of percolators |
|
|
92 | (1) |
|
|
93 | (2) |
|
|
95 | (1) |
|
4.5.5 Continuous hot extraction |
|
|
95 | (2) |
|
|
95 | (1) |
|
|
96 | (1) |
|
4.5.5.3 Advantages and disadvantages |
|
|
97 | (1) |
|
4.5.6 Aqueous alcoholic extraction |
|
|
97 | (1) |
|
4.5.7 Countercurrent extraction |
|
|
98 | (1) |
|
|
98 | (1) |
|
|
98 | (3) |
|
4.5.8.1 Types of distillation for extraction |
|
|
99 | (2) |
|
4.5.9 Supercritical fluid extraction |
|
|
101 | (2) |
|
|
101 | (2) |
|
|
103 | (1) |
|
4.5.10 Microextraction techniques |
|
|
103 | (23) |
|
4.5.10.1 Solid-phase microextraction |
|
|
103 | (1) |
|
4.5.10.2 Stir bar sportive extraction (SBSE) |
|
|
104 | (1) |
|
4.5.10.3 Liquid-phase microextraction |
|
|
105 | (1) |
|
4.6 Common plant/herbal extracts and their therapeutic applications |
|
|
106 | (1) |
|
4.7 Ongoing clinical trials on natural ingredients/botanical extracts |
|
|
106 | (1) |
|
|
106 | (6) |
|
|
112 | (1) |
|
|
113 | (10) |
5 Taste-Masking Techniques in Nutraceutical and Functional Food Industry |
|
123 | (22) |
|
|
|
|
|
|
|
|
124 | (2) |
|
5.2 Sensory evaluation strategies for taste masking |
|
|
126 | (3) |
|
5.2.1 Insent taste-sensing system |
|
|
127 | (1) |
|
5.2.2 α-ASTREE electronic tongue |
|
|
127 | (1) |
|
5.2.3 Carbon nanotubule field-effect transistor bioelectronic sensors |
|
|
128 | (1) |
|
|
128 | (1) |
|
5.3 Conventional techniques used in taste masking |
|
|
129 | (7) |
|
5.3.1 Sweeteners and flavors |
|
|
129 | (1) |
|
|
129 | (1) |
|
|
130 | (1) |
|
|
130 | (1) |
|
|
131 | (1) |
|
|
132 | (1) |
|
|
132 | (1) |
|
|
133 | (1) |
|
5.3.7 Ion-exchange resins |
|
|
134 | (1) |
|
|
135 | (1) |
|
5.3.9 Supercritical fluids |
|
|
135 | (1) |
|
|
136 | (2) |
|
5.4.1 Nanohybrid technology |
|
|
136 | (1) |
|
|
136 | (1) |
|
5.4.3 Solvent-free cold extrusion |
|
|
137 | (1) |
|
5.4.4 Off-taste masking agents |
|
|
137 | (1) |
|
5.4.5 Lipid nanoparticles |
|
|
137 | (1) |
|
5.4.6 Porous microspheres |
|
|
137 | (1) |
|
5.4.7 Multi-particulate rupture |
|
|
138 | (1) |
|
|
138 | (3) |
|
5.5.1 Microcaps technology® |
|
|
138 | (1) |
|
|
139 | (1) |
|
|
139 | (1) |
|
|
139 | (1) |
|
|
139 | (1) |
|
|
140 | (1) |
|
|
140 | (1) |
|
|
140 | (1) |
|
|
140 | (1) |
|
|
141 | (1) |
|
|
141 | (4) |
6 The Effect of Bitter Components on Sensory Perception of Food and Technology Improvement for Consumer Acceptance |
|
145 | (22) |
|
|
|
|
146 | (1) |
|
|
147 | (2) |
|
|
147 | (1) |
|
|
147 | (1) |
|
|
147 | (1) |
|
|
147 | (1) |
|
|
148 | (1) |
|
|
149 | (1) |
|
6.4 Aspects of taste perception |
|
|
149 | (1) |
|
|
150 | (3) |
|
6.5.1 A common myth: Bitter is in back, sweet is in front |
|
|
150 | (1) |
|
6.5.2 Mechanisms of bitter taste perception |
|
|
151 | (1) |
|
6.5.3 Bitter taste perception |
|
|
152 | (1) |
|
6.5.4 Bitter taste receptors as potential therapeutic targets |
|
|
153 | (1) |
|
6.6 Genetics of sweet and bitter perception |
|
|
153 | (2) |
|
6.6.1 Naturally occurring alleles |
|
|
153 | (1) |
|
6.6.2 Cross-species comparisons |
|
|
154 | (1) |
|
6.6.3 Family and twin studies |
|
|
154 | (1) |
|
6.7 Taste perception and behavior |
|
|
155 | (1) |
|
6.7.1 Challenges in the population |
|
|
155 | (1) |
|
6.7.2 Bitter taste and food rejection |
|
|
156 | (1) |
|
6.8 Consumer acceptance of functional foods |
|
|
156 | (1) |
|
6.8.1 Socio-demographic determinants |
|
|
156 | (1) |
|
6.8.2 Cognitive and attitudinal determinants |
|
|
157 | (1) |
|
6.9 Challenges in consumer acceptance and successful marketing of products |
|
|
157 | (2) |
|
6.9.1 Role of sensory science in decision making |
|
|
158 | (1) |
|
6.9.2 Sensory evaluation and quality of food |
|
|
159 | (1) |
|
6.10 Taste improvement technology |
|
|
159 | (3) |
|
|
160 | (1) |
|
6.10.2 Suppression of mixture |
|
|
160 | (1) |
|
6.10.3 Masking by encapsulation |
|
|
161 | (1) |
|
6.10.4 Using food technology to create new flavors |
|
|
162 | (1) |
|
6.10.5 Role of umami in food science |
|
|
162 | (1) |
|
|
162 | (1) |
|
|
163 | (4) |
7 Sensory Qualities and Nutraceutical Applications of Flavors of Terpenoid Origin |
|
167 | (34) |
|
|
|
|
|
167 | (2) |
|
7.2 Sensory qualities of terpenes |
|
|
169 | (5) |
|
7.3 Nutraceutical applications of terpene flavors |
|
|
174 | (20) |
|
|
180 | (4) |
|
7.3.1.1 Biological properties of citral |
|
|
180 | (4) |
|
|
184 | (3) |
|
7.3.2.1 Biological properties of geraniol |
|
|
184 | (3) |
|
|
187 | (19) |
|
7.3.3.1 Biological properties of menthol |
|
|
189 | (5) |
|
|
194 | (1) |
|
|
194 | (7) |
8 The Biopsychology of Flavor Perception and Its Application to Nutraceuticals |
|
201 | (16) |
|
|
|
201 | (1) |
|
8.2 Sensory and affective responses to food and drink |
|
|
202 | (4) |
|
8.3 Flavor problems with nutraceuticals |
|
|
206 | (3) |
|
|
206 | (1) |
|
|
207 | (1) |
|
|
208 | (1) |
|
8.3.3.1 Texture and astringency |
|
|
208 | (1) |
|
|
208 | (1) |
|
|
208 | (1) |
|
8.4 Solutions to flavor-related problems |
|
|
209 | (4) |
|
|
209 | (2) |
|
|
211 | (1) |
|
|
212 | (1) |
|
|
213 | (1) |
|
|
214 | (3) |
9 Flavor Nanotechnology: Recent Trends and Applications |
|
217 | (18) |
|
|
|
|
|
217 | (5) |
|
9.2 Nanotechnology in flavors |
|
|
222 | (1) |
|
9.3 Techniques for nanoencapsulation of flavor components |
|
|
223 | (5) |
|
|
223 | (1) |
|
|
224 | (1) |
|
9.3.3 Coacervation phase separation |
|
|
224 | (1) |
|
|
225 | (1) |
|
9.3.5 Supercritical fluid technology |
|
|
226 | (1) |
|
|
227 | (1) |
|
|
227 | (1) |
|
9.4 Applications of nanoencapsulation in flavor compounds |
|
|
228 | (1) |
|
9.5 Evaluation of flavor products |
|
|
229 | (1) |
|
|
230 | (1) |
|
|
230 | (5) |
10 Nanoencapsulation of Flavors: Advantages and Challenges |
|
235 | (38) |
|
|
|
|
|
|
|
|
|
236 | (4) |
|
|
236 | (1) |
|
10.1.2 Production of natural flavoring substances |
|
|
236 | (3) |
|
10.1.2.1 Extraction processes |
|
|
237 | (1) |
|
10.1.2.2 Distillation process |
|
|
237 | (1) |
|
10.1.2.3 Solvent extraction |
|
|
238 | (1) |
|
10.1.2.4 Supercritical fluid extraction |
|
|
238 | (1) |
|
10.1.2.5 Microwave extraction |
|
|
238 | (1) |
|
10.1.2.6 Pressurized liquid extraction |
|
|
239 | (1) |
|
10.1.3 Biotechnological production processes |
|
|
239 | (1) |
|
|
239 | (1) |
|
10.2 Perception of flavor |
|
|
240 | (2) |
|
10.3 Flavor encapsulation |
|
|
242 | (2) |
|
10.3.1 Flavor encapsulation challenges |
|
|
242 | (1) |
|
10.3.2 Applications of encapsulation |
|
|
242 | (2) |
|
10.4 Methods of nanoencapsulation of flavors |
|
|
244 | (14) |
|
10.4.1 Physical/mechanical methods |
|
|
245 | (6) |
|
|
245 | (1) |
|
10.4.1.2 Spray cooling/spray chilling or spray congealing |
|
|
246 | (2) |
|
10.4.1.3 Fluid bed spray coating |
|
|
248 | (1) |
|
|
248 | (2) |
|
|
250 | (1) |
|
10.4.1.6 Co-crystallization |
|
|
251 | (1) |
|
10.4.2 Physicochemical methods |
|
|
251 | (5) |
|
|
251 | (1) |
|
10.4.2.2 Liposome entrapment |
|
|
252 | (4) |
|
|
256 | (2) |
|
10.4.3.1 Molecular inclusion |
|
|
256 | (2) |
|
10.4.3.2 Interfacial polymerization |
|
|
258 | (1) |
|
|
258 | (6) |
|
|
260 | (1) |
|
10.5.2 Controlled flavor release |
|
|
260 | (15) |
|
10.5.2.1 Flavor release by diffusion |
|
|
262 | (1) |
|
10.5.2.2 Flavor release by degradation |
|
|
262 | (1) |
|
10.5.2.3 Flavor release by swelling |
|
|
262 | (1) |
|
10.5.2.4 Flavor release by melting |
|
|
263 | (1) |
|
10.5.2.5 Stability of encapsulated flavors |
|
|
263 | (1) |
|
10.5.2.6 Characterization of nanocapsules |
|
|
263 | (1) |
|
|
264 | (1) |
|
|
265 | (8) |
11 Nanoencapsulated Nutraceuticals: Pros and Cons |
|
273 | (38) |
|
|
|
|
|
|
|
274 | (1) |
|
11.2 Definition of nutraceutical |
|
|
275 | (2) |
|
11.2.1 Categories of nutraceuticals |
|
|
276 | (1) |
|
11.2.1.1 Dietary supplements |
|
|
276 | (1) |
|
11.2.1.2 Functional foods |
|
|
276 | (1) |
|
|
277 | (1) |
|
|
277 | (1) |
|
11.3 Nutraceutical nomenclature in Canada and the United States |
|
|
277 | (1) |
|
11.3.1 Nomenclature in Canada |
|
|
277 | (1) |
|
11.3.2 Nomenclature in the United States |
|
|
277 | (1) |
|
11.4 International market potential and quality issues |
|
|
277 | (1) |
|
11.4.1 Market potential of nutraceuticals |
|
|
277 | (1) |
|
11.4.2 Global quality issues |
|
|
278 | (1) |
|
11.5 Natural antioxidants |
|
|
278 | (2) |
|
|
278 | (1) |
|
|
279 | (1) |
|
|
279 | (1) |
|
11.6 Nanotechnology in drug delivery systems |
|
|
280 | (1) |
|
11.6.1 Advantages of nanotechnology |
|
|
280 | (1) |
|
11.6.2 Goals of nanotechnology |
|
|
280 | (1) |
|
11.7 Nanoparticle preparation |
|
|
280 | (4) |
|
11.8 Nanoencapsulation of bioactive agents/ingredients |
|
|
284 | (4) |
|
11.8.1 Encapsulation materials |
|
|
285 | (3) |
|
|
285 | (1) |
|
|
286 | (1) |
|
|
287 | (1) |
|
|
287 | (1) |
|
11.9 Methods of producing chitosan nanoparticles |
|
|
288 | (3) |
|
11.9.1 Coacervation/precipitation |
|
|
288 | (1) |
|
11.9.2 Emulsion-droplet coalescence |
|
|
288 | (1) |
|
|
289 | (1) |
|
11.9.4 Ionotropic gelation |
|
|
290 | (1) |
|
11.10 Applications of chitosan nanoparticles |
|
|
291 | (1) |
|
11.11 Activity of nanoparticles |
|
|
291 | (4) |
|
11.11.1 Controlled release of liposomes |
|
|
292 | (1) |
|
11.11.2 Antimicrobial activity of nanoemulsions |
|
|
293 | (1) |
|
11.11.3 Protein-based nanoencapsulates |
|
|
294 | (1) |
|
11.11.4 Polysaccharide-based nanoencapsulates |
|
|
295 | (1) |
|
11.11.5 Inorganic-based nanoencapsulates |
|
|
295 | (1) |
|
11.12 Characterization of nanoparticles by analytical methods |
|
|
295 | (5) |
|
11.12.1 Electron microscopy: Transmission electron microscopy and scanning electron microscopy |
|
|
296 | (1) |
|
11.12.2 Dynamic light scattering |
|
|
296 | (1) |
|
11.12.3 In-vitro evaluation of nanoparticles |
|
|
297 | (2) |
|
|
299 | (1) |
|
11.13 Potential health benefits |
|
|
300 | (2) |
|
11.13.1 Advantages of nanoencapsulation |
|
|
300 | (2) |
|
11.13.1.1 Nanoencapsulation of antioxidants and flavoring agents |
|
|
300 | (2) |
|
11.13.1.2 Nanoencapsulation of anti-cancer agents |
|
|
302 | (1) |
|
11.14 Disadvantages of nanoencapsulation |
|
|
302 | (1) |
|
|
303 | (1) |
|
|
303 | (8) |
Index |
|
311 | |