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Forensic Histopathology: Fundamentals and Perspectives 1st ed. 2011. Corr. 5th printing 2013 [Hardback]

  • Formāts: Hardback, 454 pages, height x width: 260x193 mm, weight: 1403 g, 370 Illustrations, color; XXIV, 454 p. 370 illus. in color., 1 Hardback
  • Izdošanas datums: 08-Sep-2011
  • Izdevniecība: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • ISBN-10: 3642206581
  • ISBN-13: 9783642206580
Citas grāmatas par šo tēmu:
  • Formāts: Hardback, 454 pages, height x width: 260x193 mm, weight: 1403 g, 370 Illustrations, color; XXIV, 454 p. 370 illus. in color., 1 Hardback
  • Izdošanas datums: 08-Sep-2011
  • Izdevniecība: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • ISBN-10: 3642206581
  • ISBN-13: 9783642206580
Citas grāmatas par šo tēmu:

Forensic Histopathology presents findings in forensic histology, immunohistochemistry, and cytology based on microscopic investigations. The text provides practitioners with detailed information and guidance on how microscopy can help to clarify the cause of sudden and unexpected death.



This book, which combines the features of an atlas and a textbook, presents findings in forensic histology, immunohistochemistry, and cytology based on microscopic investigations using different stainings and different antibodies. The principal aim is to provide practitioners with detailed information and guidance on how microscopy can help to clarify the cause of sudden and unexpected death. Many of the topics will be of interest not only to forensic pathologists but also to general pathologists, whether practitioners or researchers. Examples include the pathology of drug abuse, wound age determination, adverse drug reactions, histopathology of the sudden infant death syndrome, and age determination of myocardial infarction. Both typical and unusual findings are demonstrated with the aid of numerous high-quality color illustrations, and other key literature in forensic histology and immunohistochemistry is highlighted for each topic.

Recenzijas

From the reviews:

Strength of this book, is the fact that it combines the features of both an atlas and a textbook, a feature that is not present in the other books available on the subject. Dettmeyer gives an exhaustive literature overview with the main results of both earlier and most recent publications on the different topics of forensic histopathology in the respective text sections. it is written from the forensic pathology practitioners point of view. However, many topics will also be of interest to clinical pathologists. (Michael Tsokos, Forensic Science, Medicine and Pathology, Vol. 9, 2013)

In this present work over the course of 20 chapters, he offers the reader profound insights into the areas of application of forensic histopathology as well as its significance. The 370 colour plates are marked by their high quality. The legends are informative and lucid. Each chapter is based on a synopsis of the latest literature on the subject. This book is to be recommended to all physicians involved in forensic work as a new standard work on forensic histopathology.--- (Heidi Pfeiffer, International Journal of Legal Medicine, November, 2011)

1 Introduction
1(16)
1.1 Microscopic Examinations and Medical Malpractice Cases
6(8)
Case 1
7(1)
Case 2
8(1)
Case 3
9(1)
Case 4
10(1)
Case 5
11(1)
Case 6
12(1)
Case 7
13(1)
References
14(3)
2 Staining Techniques and Microscopy
17(20)
2.1 Conventional Histological Staining
17(3)
2.1.1 Background Staining and Artifacts in Conventional Staining Methods
19(1)
2.2 Immunohistochemical Techniques
20(8)
2.2.1 Methods of Antigen Demasking
23(1)
2.2.2 ABC-Method
24(1)
2.2.3 APAAP-Method
24(1)
2.2.4 Background Staining and Artifacts in Immunohistochemical Staining
24(4)
2.3 Selection of Antigens and Antibodies
28(3)
2.4 Special Examination Techniques
31(2)
2.4.1 TUNEL Assay
31(1)
2.4.2 In Situ Hybridization
31(1)
2.4.3 Confocal Laser Scanning Microscopy
32(1)
2.4.4 Electron Microscopy
32(1)
2.4.5 Laser Microdissection
33(1)
References
33(4)
3 Histopathology of Selected Trauma
37(30)
3.1 Hemorrhage, Necrosis, and Skeletal Muscle Trauma
37(6)
3.1.1 Hemorrhage
38(3)
3.1.2 Necrosis
41(1)
3.1.3 Skeletal Muscle Trauma
41(2)
3.2 Neck Trauma
43(2)
3.3 Cardiac Concussion
45(1)
3.4 Drowning -- Water-Submerged Victims
46(5)
3.4.1 Determining the Postmortem Interval in Water-Submerged Corpses
47(1)
3.4.2 Histology of the Drowned Lung
48(2)
3.4.3 Detection of Diatoms in Death by Drowning
50(1)
3.5 Injury by Firearms and Explosives
51(3)
3.6 Stab Wounds and Hemorrhage
54(2)
3.6.1 Stab Wounds
54(1)
3.6.2 Fatal Hemorrhage with Subendocardial Hemorrhage
54(2)
3.7 Asphyxiation
56(1)
3.8 Differentiation Between SIDS and Asphyxiation
57(1)
3.9 Some Histopathologic Changes Due To Cardiopulmonary Resuscitation
58(1)
3.10 Death by Starvation/Dehydration
58(1)
3.11 Traumatic Injury to the Kidneys, Liver and Pancreas
59(1)
References
60(7)
4 Histopathology and Drug Abuse
67(28)
4.1 Pulmonary Histopathological Findings
67(7)
4.1.1 Pulmonary Edema
69(1)
4.1.2 Pulmonary Granulomatosis (So-Called Junkie Pneumopathy)
70(3)
4.1.3 Pneumonia
73(1)
4.2 Cardiac Histopathological Findings in Intravenous Drug Abuse
74(4)
4.2.1 Myocarditis
74(2)
4.2.2 Cocaine-Induced Findings
76(1)
4.2.3 Endocarditis
77(1)
4.3 Drug-Associated Nephropathies
78(5)
4.3.1 Glomerulonephritis and Glomerulosclerosis
79(4)
4.4 Hepatic Histopathological Findings
83(3)
4.4.1 Hepatitis
83(1)
4.4.2 Peliosis Hepatis
84(1)
4.4.3 Amphetamine-Induced Liver Cell Necroses
85(1)
4.4.4 Intravenous Injection of Methadone
85(1)
4.5 Neuropathological Findings
86(1)
4.6 Organ Infarction After Drug Consumption
86(1)
4.7 Injection-Related Tissue and Vascular Wall Damage
87(2)
References
89(6)
5 Toxin- and Drug-Induced Pathologies
95(42)
5.1 Hepatotoxic Histopathological Findings
98(7)
5.1.1 Nonspecific Drug-Induced Hepatitis
99(3)
5.1.2 Hepatic Peliosis and Focal Nodular Hyperplasia
102(3)
5.1.3 Hepatic Lipofuscin
105(1)
5.1.4 Transfusion Siderosis of the Liver
105(1)
5.2 Histopathology of the Cardiotoxic Effects of Selected Medications: Drug-Induced Myocarditis
105(5)
5.3 Histopathology of Other Special Intoxications
110(21)
5.3.1 Special Histopathology in the Case of Colchicine Intoxication
111(2)
5.3.2 Special Histopathology in Cases of Ethylene Glycol Intoxication
113(3)
5.3.3 Lethal Death Cap Intoxication
116(3)
5.3.4 Histopathological Findings in Anabolic Abuse
119(2)
5.3.5 Reye's Syndrome
121(1)
5.3.6 Antibiotic-Induced Pseudomembranous Colitis
122(1)
5.3.7 Acute Drug-Induced Anaphylaxis (Anaphylactic Shock)
122(3)
5.3.8 Anorganic Toxins, Metals, Metalloids, Carbon Monoxide, and Oxygen
125(1)
5.3.9 Intoxication by Medication (Sleep Medications, Analgesics, Anesthetics, etc.), Organic Poisons, Solvents, Pesticides (Herbicides, Fungicides, etc.), and Other Selected Poisons
125(4)
5.3.10 Further Fatal Adverse Drug Reactions and Medical Errors
129(2)
References
131(6)
6 Alcohol-Related Histopathology
137(12)
6.1 Alcoholic Liver Pathology
137(4)
6.2 The Pancreas
141(1)
6.3 Alcoholic Cardiomyopathy
142(4)
6.3.1 Other Alcohol-Associated Histopathological Findings
145(1)
References
146(3)
7 Heat, Fire, Electricity, Lightning, Radiation, and Gases
149(16)
7.1 Heat and Fire
149(6)
7.1.1 The Effects of Heat on the Skin
149(1)
7.1.2 Heat Inhalation Trauma
150(3)
7.1.3 Histological and Immunohistochemical Findings in the Case of Burn Shock
153(2)
7.2 Electricity and Lightning stroke
155(4)
7.2.1 Electrocution
155(3)
7.2.2 Lightning
158(1)
7.3 Malignant Hyperthermia
159(1)
7.4 Radiation
160(1)
7.5 Gases
161(1)
References
161(4)
8 Hypothermia
165(8)
References
170(3)
9 Thrombosis and Embolism
173(18)
9.1 Thrombosis
173(5)
9.2 Embolism
178(9)
9.2.1 Thromboembolism
179(1)
9.2.2 Fat and Bone Marrow Embolism
179(5)
9.2.3 Air Embolism
184(1)
9.2.4 Amniotic Fluid Embolism
185(1)
9.2.5 Other Embolisms
186(1)
References
187(4)
10 Vitality, Injury Age, Determination of Skin Wound Age, and Fracture Age
191(20)
10.1 Vitality of an Injury or Skin Wound
192(3)
10.2 Wound Age in the Case of Tissue Injuries
195(5)
10.2.1 Invasion of Granulocytes
196(1)
10.2.2 Occurrence of Macrophages
197(1)
10.2.3 Granulation Tissue Formation
198(1)
10.2.4 Inflammation Age in the Case of Fibrinous and Purulent Peritonitis, Pleurisy, and Pericarditis
198(1)
10.2.5 Injury Age of Muscle Trauma
199(1)
10.3 Skin Wounds
200(3)
10.4 Bone Fractures and Fracture Healing
203(2)
References
205(6)
11 Aspiration and Inhalation
211(20)
11.1 Aspiration of Water
211(2)
11.2 Aspiration of Blood
213(2)
11.3 Aspiration of Gastric Content or Chyme
215(1)
11.4 Amniotic Fluid Aspiration
216(3)
11.5 Aspiration of Barium Sulfate
219(1)
11.6 Aspiration of Textile Material and Fibers
219(1)
11.7 Aspiration of Other Substances
220(1)
11.8 Inhalation of Smoke, Dust, Gases, and Allergens
221(5)
11.8.1 Histopathological Findings After Inhalation of Volatile Substances
221(1)
11.8.2 Asthma and Fatal Anaphylaxis
222(4)
References
226(5)
12 Forensic-Histological Diagnosis of Species, Gender, Age, and Identity
231(10)
12.1 Species Diagnosis
231(1)
12.2 Cytological Gender Determination
231(3)
12.3 Tissue and Organ Determination
234(1)
12.4 ABO Blood Type Verification
234(1)
12.5 Histological Age Estimation
234(1)
12.5.1 Tooth Cementum Annulation for Age Estimation
234(1)
12.5.2 Age Estimation from Human Bones
234(1)
12.5.3 Age Estimation Using Routine Histology
235(1)
12.6 Evidence of Tattoo Remnants in the Identification Process
235(2)
References
237(4)
13 Coronary Sclerosis, Myocardial Infarction, Myocarditis, Cardiomyopathy, Coronary Anomalies, and the Cardiac Conduction System
241(42)
13.1 Sudden Coronary Death
241(4)
13.2 Myocardial Infarction
245(4)
13.3 Acute and Chronic Viral Myocarditis
249(9)
13.3.1 Acute Viral Myocarditis
250(7)
13.3.2 Chronic Myocarditis
257(1)
13.4 Non-virus Based Myocarditis
258(4)
13.4.1 Bacterial Myocarditis
258(1)
13.4.2 Tuberculous Myocarditis
259(1)
13.4.3 Fungal Myocarditis
260(1)
13.4.4 Rheumatoid Myocarditis
261(1)
13.4.5 Giant Cell Myocarditis
261(1)
13.4.6 Myocardial Involvement in Sarcoidosis
262(1)
13.4.7 Eosinophilic Myocarditis
262(1)
13.5 Cardiomyopathy
262(7)
13.5.1 Hypertrophic Cardiomyopathy
263(1)
13.5.2 Dilative Cardiomyopathy (DCM)
264(2)
13.5.3 Arrhythmogenic Right-Ventricular Cardiomyopathy/Dysplasia (ARVCM)
266(1)
13.5.4 Isolated Noncompaction Cardiomyopathy
267(1)
13.5.5 Alcoholic Cardiomyopathy
268(1)
13.5.6 Rare Forms of Cardiomyopathy
268(1)
13.6 Coronary Anomalies
269(1)
13.7 Cardiac Conduction System: CCS
270(2)
13.7.1 Examining the CCS
270(1)
13.7.2 Histopathologic Findings in the CCS
271(1)
References
272(11)
14 Vascular, Cardiac Valve, and Metabolic Diseases
283(20)
14.1 Vascular Diseases
283(5)
14.1.1 General, Coronary, and Cerebral Sclerosis
284(1)
14.1.2 Aneurysms
284(1)
14.1.3 Dissecting Aortic Aneurysm in Idiopathic Cystic Medial Necrosis
284(3)
14.1.4 Marfan Syndrome
287(1)
14.1.5 Ehlers--Danlos Syndrome
287(1)
14.1.6 Aneurysms in Other Arteries
288(1)
14.2 Arteritis
288(6)
14.2.1 Syphilitic Mesaortitis
288(1)
14.2.2 Suppurative Aortitis in Atherosclerosis
289(1)
14.2.3 Giant-Cell Arteritis
289(2)
14.2.4 Isolated Coronary Arteritis
291(1)
14.2.5 Takayasu's Arteritis
292(1)
14.2.6 Kawasaki Disease
293(1)
14.2.7 Drug-Associated Vasculitis
293(1)
14.3 Heart Valve Defect -- Endocarditis
294(1)
14.4 Amyloidosis
294(2)
14.5 Hemochromatosis
296(2)
References
298(5)
15 Lethal Infections, Sepsis, and Shock
303(30)
15.1 Pneumonias
303(7)
15.1.1 Purulent Bronchopneumonia
304(1)
15.1.2 Lobar Pneumonia and Carnificating Pneumonia
304(1)
15.1.3 Fungal Pneumonia
305(1)
15.1.4 Pulmonary Tuberculosis
306(3)
15.1.5 Viral Pneumonia
309(1)
15.1.6 Acute Interstitial Pneumonitis (Hamman--Rich Syndrome)
309(1)
15.2 Pancreatitis
310(1)
15.3 Malaria
311(1)
15.4 Clostridia
312(1)
15.5 Measles
312(1)
15.6 Hydatid Disease (Echinococcosis)
313(1)
15.7 Ascending Cholangitis
314(1)
15.8 Ascending Urinary Tract Infections
315(1)
15.9 Glomerulonephritis
315(2)
15.10 OPSI Syndrome
317(2)
15.11 Shock
319(5)
15.12 Iatrogenic Infections
324(1)
15.13 Allergies, Insect Bites, and Anaphylactic Shock
325(1)
15.14 H1N1-Infection
326(2)
15.15 Black Esophagus
328(1)
References
328(5)
16 Endocrine Organs
333(14)
16.1 Diabetes
333(3)
16.2 Loss of Adrenocortical Lipids
336(1)
16.3 Acute Primary Adrenal Insufficiency (Addison's Disease)
336(1)
16.4 Fatal Pheochromocytoma
337(1)
16.5 Thyroid and Parathyroid Dysfunction
338(6)
16.5.1 The Thyroid Gland
339(3)
16.5.2 Parathyroid Glands
342(2)
16.6 Hypophyseal Dysfunction
344(1)
References
344(3)
17 Pregnancy-Related Death, Death in Newborns, and Sudden Infant Death Syndrome
347(44)
17.1 Pregnancy-Related Maternal Deaths
347(2)
17.1.1 Extrauterine Pregnancy or Ruptured Tubal/Ectopic Pregnancy
348(1)
17.1.2 HELLP Syndrome
348(1)
17.1.3 Amniotic Fluid Embolism
349(1)
17.2 Perinatal Fatalities
349(6)
17.2.1 Death Shortly Before or During Birth
349(4)
17.2.2 Amniotic Infection Syndrome (AIS)
353(1)
17.2.3 Endangiitis Obliterans of the Placental Vessels
354(1)
17.3 Newborns Found Lifeless
355(1)
17.3.1 Histological Pulmonary Findings
355(1)
17.3.2 Pregnancy Decidua and the Arias-Stella Phenomenon
355(1)
17.4 Sudden Infant Death Syndrome (SIDS)
355(25)
17.4.1 The Respiratory Tract and Lungs
357(7)
17.4.2 Myocarditis and SIDS
364(8)
17.4.3 Cardiomyopathies and SIDS
372(2)
17.4.4 Hypoxia-Related Changes
374(1)
17.4.5 Histopathological Findings in the Cardiac Conduction System
375(1)
17.4.6 Salivary Glands
375(2)
17.4.7 The Liver
377(1)
17.4.8 The Thymus
378(1)
17.4.9 Endocrine Organs (Pancreas, Thyroid, Pituitary)
378(1)
17.4.10 Lymph Nodes and Spleen
379(1)
17.4.11 Additional Histopathological Findings
380(1)
References
380(11)
18 Forensic Cytology
391(10)
18.1 Detection, Isolation, and Species Identification of Cells
391(1)
18.2 Cytological Diagnosis in Sexual Offenses
392(4)
18.2.1 Sperm Detection
392(1)
18.2.2 Detection of Condom Residues
393(2)
18.2.3 Detection of Vaginal Epithelial Cells
395(1)
18.3 Identification of Cells and Tissues in the Case of Suspected Material Contamination or Mix-Up
396(1)
18.4 Transfusion Reactions
396(1)
18.5 Additional Methods of Forensic Cytological Diagnosis
397(1)
References
397(4)
19 Autolysis -- Putrefaction -- Histothanatology
401(12)
19.1 Time Frame for the Reliable Detection of Microscopic Findings
402(7)
19.2 Microscopic Examination of Stomach Contents
409(1)
References
410(3)
20 Forensic Neuropathology
413(26)
20.1 Forensic Neurotraumatology
413(6)
20.1.1 Intracranial Hematomas or Hemorrhages
414(1)
20.1.2 Wound Age Estimation of Cortical Contusions
415(2)
20.1.3 Apoptosis in Human Traumatic Brain Injury
417(1)
20.1.4 Boxing
418(1)
20.2 Ischemic and Hypoxic Changes
419(2)
20.3 Meningitis
421(2)
20.3.1 Waterhouse--Friderichsen Syndrome
421(1)
20.3.2 Posttraumatic Meningitis
422(1)
20.4 Unknown Brain Tumors and Malignant Diseases of the Central Nervous System as Cause of Death
423(1)
20.5 Nontraumatic Subarachnoid and Intracerebral Hemorrhages
423(4)
20.5.1 Ruptured Congenital Cerebral Aneurysms Within the Circle of Willis
424(1)
20.5.2 Intracerebral Arteriovenous Malformations
425(1)
20.5.3 Amyloid Angiopathy
426(1)
20.6 Shaken Baby Syndrome (SBS)
427(3)
20.7 Neuropathology of Drug Abuse
430(2)
20.8 Fahr Disease
432(1)
20.9 Epilepsy
432(1)
References
433(6)
Index 439
Professor Reinhard Dettmeyer is Head of the Institute of Forensic Medicine at Justus-Liebig University, Giessen, Germany. Professor Dettmeyer is qualified in both general pathology and forensic pathology, and studied medicine at the University of Düsseldorf and jurisprudence at the Ruhr University, Bochum. Prior to taking up his post in Giessen, he was Senior Physician in the Department of Forensic Medicine at the University of Bonn.

He has written many journal articles on forensic pathology and is co-author of several German language books on child abuse, forensic medicine, and medicolegal issues; in addition, he acted as scientific editor for Volume 2 of the comprehensive Handbuch Gerichtliche Medizin (Handbook of Forensic Medicine).