Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers.
Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene therapy and gene delivery. Written by prominent authors in the field, this book covers various aspects of gene delivery including challenges in delivering gene therapy, advances in genome editing, RNA-based gene therapy, Green nanoparticles for oligonucleotide delivery.
Additional features include"
Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing.
Includes knowledge of the current application of CRISPR/Cas9 gene-editing technique; an approach that has recently been given the Noble Prize.
Examines the development of mRNA vaccines for Covid -19 in challenging pandemic scenario
Discusses siRNA, mRNA, and DNA plasmids.
Recenzijas
"This book succeeds in presenting the challenges and barriers facing the field of nucleic acid delivery for therapeutic purposes, as well as the current status and main achievements of existing nanotechnologies in different therapeutic areas".
- Doody's Review
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Chapter 1 Challenges in Delivering Gene Therapy |
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1 | (14) |
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Chapter 2 Advances in Genome Editing: The Technology of Choice for Precise and Efficient Disease Treatment, with Special Focus on Nano Delivery Systems |
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Chapter 3 Extracellular Vesicles for Nucleic Acid Delivery: Progress and Prospects for Safe RNA-Based Gene Therapy |
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Chapter 4 Green Synthesis of Nanoparticles in Oligonucleotide Drug Delivery System |
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Chapter 5 Development of m-RNA Vaccines in Covid-19 Pandemic Scenario |
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Chapter 6 Gene Therapy for Cardiovascular Diseases: Clinical Evidences |
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Chapter 7 Current Application of CRISPR/Cas9 Gene-Editing Technique to Eradication of HIV/AIDS |
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Chapter 8 Sirna Delivery for Therapeutic Applications Using Nanoparticles |
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103 | (12) |
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Chapter 9 Clinical Perspectives on Gene Therapy for Retinal and Eye Diseases |
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Chapter 10 Herpesvirus microRNAs for Use in Gene Therapy Immune-Evasion Strategies |
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129 | (10) |
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Chapter 11 Gene Therapy and Small Molecules Used in the Treatment of Cystic Fibrosis |
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139 | (24) |
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Chapter 12 Non-Viral Delivery of Genome-Editing Nucleases for Gene Therapy |
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163 | (16) |
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Chapter 13 CRISPER Gene Therapy Recent Trends and Clinical Applications |
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179 | (16) |
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Chapter 14 Clinical Applications of Gene Therapy for Immuno-Deficiencies |
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195 | (12) |
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Chapter 15 Regulatory Challenges for Gene Delivery |
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207 | (14) |
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| Index |
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Dr. Yashwant Pathak completed his Ph.D. in Pharmaceutical Technology from Nagpur University,
India and his EMBA MS in Conflict Management from Sullivan University. He is Professor and
Associate Dean for Faculty Affairs at the College of Pharmacy, University of South Florida. Tampa,
Florida. With extensive experience in academia as well as industry, he has more than 100 publications,
two patents and two patent applications, twenty edited books published, including seven books
in Nanotechnology and six in Nutraceuticals and drug delivery systems. He has several books in cultural
studies and conflict management. He has received several National and International awards.
His recent assignment was Fulbright Senior Fellow in Indonesia for six months, where he traveled
in seven countries and lectured in more than twenty universities. He was a key note speaker at the
World Hindu Wisdom meeting in Bali, Indonesia, in June 2017 and co-chaired with the Governor
of Bali. Dr Yashwant Pathak is also a Professor of Global Health with the College of Public Health
at USF. Recently, his student completed a PhD in Global Health on homeopathy medicine and its
efficacy, a survey of 1274 patients in Pune in India. Dr Pathak is also an adjunct faculty member at
AirLangga University College of Public Health at Surabaya Indonesia.
