Contributors |
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ix | |
Preface |
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xi | |
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1 Perspectives on divergence of early developmental regulatory pathways: Insight from the evolution of echinoderm double negative gate |
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1 | (24) |
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2 | (1) |
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2 Echinoderm mesoderm specification pathways |
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3 | (7) |
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3 Evolution of echinoderm double negative gate |
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10 | (4) |
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4 Stepwise and gradual modification behind the drastic divergence of hesC function |
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14 | (2) |
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5 Overview of early developmental innovations in other organisms |
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16 | (4) |
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6 Conclusions and further insights |
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20 | (5) |
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21 | (4) |
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2 Development of a larval nervous system in the sea urchin |
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25 | (24) |
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1 Development and anatomy of the sea urchin larval nervous system |
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27 | (1) |
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2 Patterning the anterior neurectoderm (ANE) |
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27 | (4) |
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3 Neurogenesis in the ANE |
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31 | (2) |
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4 Patterning the ciliary band domain |
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33 | (2) |
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5 Neural specification in and near the ciliary band |
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35 | (4) |
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6 Patterning the endomesoderm |
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39 | (1) |
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7 Specification of neurons originating along the gut |
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40 | (1) |
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8 A functional nervous system in the larva |
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41 | (2) |
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43 | (6) |
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43 | (1) |
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43 | (6) |
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3 Post-transcriptional regulation of factors important for the germ line |
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49 | (30) |
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50 | (9) |
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2 Multiple transcripts from the same gene |
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59 | (2) |
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3 The differential regulation of mRNAs encoding germline factors |
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61 | (3) |
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4 Translational regulation of the germ line and their factors |
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64 | (2) |
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5 Turnover of germline proteins |
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66 | (3) |
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6 What does all this mean in terms of the germline vs somatic cell fates? |
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69 | (10) |
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72 | (7) |
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4 Extreme phenotypic divergence and the evolution of development |
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79 | (34) |
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80 | (1) |
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2 Studying developmental evolution |
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81 | (5) |
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3 Life history and the evolution of development |
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86 | (6) |
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4 Evolution of developmental processes within Heliocidaris |
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92 | (12) |
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104 | (9) |
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107 | (1) |
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107 | (6) |
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5 Lessons from a transcription factor: Alxl provides insights into gene regulatory networks, cellular reprogramming, and cell type evolution |
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113 | (36) |
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Jennifer Guerrero-Santoro |
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114 | (1) |
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2 The alxl gene and protein |
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114 | (9) |
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3 Alxl and gene regulatory network (GRN) architecture |
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123 | (12) |
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4 Alxl and other developmental and evolutionary processes |
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135 | (4) |
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139 | (10) |
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140 | (1) |
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140 | (9) |
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6 Pigment cells: Paragons of cellular development |
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149 | (34) |
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150 | (1) |
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2 Pigment cells are a distinct mesodermal lineage |
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151 | (2) |
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3 Pigment cell precursors transition to mesenchyme, migrate, and re-insert in epithelium |
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153 | (3) |
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156 | (3) |
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5 Pigment cells and archenteron formation |
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159 | (1) |
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6 Localized maternal factors in the egg lead to short range signals that cause differentiation of pigment cells |
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160 | (4) |
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7 A network of interacting genes controls pigment cell differentiation |
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164 | (2) |
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8 Detailed descriptions of lineage specific genes provide insights into the enigmatic functions of pigment cells |
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166 | (4) |
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9 Pigment cells as immunocytes |
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170 | (2) |
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172 | (11) |
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176 | (1) |
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176 | (7) |
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7 Dorsal-ventral axis formation in sea urchin embryos |
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183 | (28) |
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184 | (2) |
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2 DV morphological differences during planktotrophic sea urchin embryogenesis |
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186 | (2) |
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3 Oxidase activity is related to the sea urchin dorsoventral axis |
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188 | (1) |
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4 Molecular mechanisms patterning the planktotrophic sea urchin DV axis |
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189 | (11) |
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5 DV patterning in lecithotrophic sea urchins |
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200 | (2) |
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6 Evolution of DV patterning in sea urchins |
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202 | (2) |
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204 | (7) |
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204 | (1) |
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204 | (7) |
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8 Micromere formation and its evolutionary implications in the sea urchin |
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211 | (21) |
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212 | (3) |
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2 Micromere formation in the sea urchin embryo |
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215 | (2) |
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3 Unique properties of the micromere |
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217 | (7) |
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4 Mechanism of micromere formation through asymmetric cell division |
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224 | (5) |
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5 Unique transcriptional and translational activity of the micromere and its descendants |
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229 | (2) |
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6 Conclusions and perspectives |
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231 | (1) |
Acknowledgment |
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232 | (1) |
References |
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232 | |