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E-grāmata: Genomics in Biosecurity: Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts

(Scientific Advisor, The Golden Helix Foundation, Craven House, London, UK, and Post Doc Researcher, Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, University of Patras, Rio Patras, Greece)
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Genomics in Biosecurity: Principles and Applications of Genomic Technologies in Expanded Biosecurity ConceptsPalielināt
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Genomics in Biosecurity: Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts, in the Translational and Applied Genomics series, explains in definite and practical terms the applicability of genomic technologies in every aspect of biosecurity, from emergent diagnostics to bioterrorism, agroterrorism, next generation biowarfare, biosurveillance and risk assessment. This book offers an integrated discussion of genomics and GCBR (global catastrophic biological risks) events, considering both basic aspects of biosecurity genomics and application of genomic technologies to drive new solutions. Readers will find evidence-based strategies to apply genomics in disease and pathogen monitoring and diagnosis, and more.

Social aspects of GCBR events and genomic biosecurity, such as issues of terrorism, policy ethics, and practice, are also considered in-depth.

  • Examines the use of genomics in pathogen monitoring and diagnosis, biosurveillance, and countermeasures for spontaneous and perpetrated events
  • Discusses social, ethical, and policy aspects of GCBR events and the use of genomic technologies in biosecurity
  • Empowers new solutions in biorestoration, biocrime, counterbioterrorism, disaster management, and humanitarian crisis response
  • Features chapter contributions from a range of international specialists

Part I. The Spontaneous Risk: Microbes and Bugs
1. Exploring the concepts: Biosecurity, biodefense and biovigilance
2. The concept of humanome and the microbiomic dimension
3. Global catastrophic biological risks: Nature and response
4. Surveillance policies, levels, patterns, and techniques
5. The emerging pathogens: Nature, status, and threat
6. Non-microbial biothreats: DNA, prions, and (bio)regulators/(bio)toxins
7. Public health microbiomics

Part II. The Perpetrated Biothreat: Bioterrorism, Biocrime, and Biowarfare
8. Bio-offense: Black biology
9. Bio-offense: Technical means, tactical approaches, operational orientations, and strategic concepts

Part III. Biodefense Response and Intervention
10. Biodefense response: Cognition and diagnosis
11. Bio-defence build 2.0: The muscle
12. The genomic dimension in biodefense: Therapeutics
13. The genomic dimension in biodefense: Decontamination
14. Regulation and legislation
15. Epilogue: Resilience and preparedness, the case study of the United States

Dr. Manousos E. Kambouris serves as a Scientific Advisor for the Golden Helix Foundation, Craven House, London, UK, an international non-profit research organization aiming to advance research and education in the area of genomic and personalized medicine and as a Post Doc Researcher in the Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, University of Patras. Dr. Kambouris has long participated in different aspects and applications of microbiology, human genomics, biosecurity and cancer research. In his own work, he pursues an integrative approach to microbiomics, employing various -omics-driven approaches and realizing their application in human health, selective and personalized medicine, and panbiosurveillance among other areas. He has published widely in such peer-reviewed journals as OMICS-JIB, Hemoglobin, Medical Mycology, FEMS Immunology & Medical Microbiology, Public Health Genomics, and Future Microbiology.
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