This book offers a comprehensive review of the global exosome trials in neurology and ophthalmology, that are registered with the United States National Institutes of Health website, clinicaltrials.gov. Clinicaltrials.gov is the largest listing of research studies in the world. The study titles are provided, as is the country of origin and the Clinical Trial Number in order to make it easier for the reader to locate the study and obtain further information. The book begins with an introduction to exosomes and exosome therapy, which involves the injection or infusion of exosomes, making it less invasive than traditional gene therapy, which involves the introduction, removal, or alteration of genetic material. Subsequent chapters discuss neurologic exosome therapy trials and ophthalmic exosome therapy trials. The book covers topics such as Alzheimer's Disease, back pain, cancer, dementia, neuralgia, dry eyes, diabetic retinopathy, and macular hole. Chapters will examine currently recruiting studies as well as soon-to-be recruiting studies.
Global Exosome Trials in Neurology and Ophthalmology will be a valuable resource for neurologists, neurosurgeons, ophthalmologists, related and allied physicians, PhDs, and researchers.
.- Section
1. Introduction.
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Chapter
1. What are Exosomes?
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Chapter
2. Tables.
.- Section 2: Neurologic Exosome Therapy Trials.
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Chapter
3. Alzheimer's Disease.
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Chapter
4. Back Pain.
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Chapter
5. Cancer.
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Chapter
6. Depression, Anxiety, and Dementia.
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Chapter
7. Epilepsy.
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Chapter
8. Knee Pain.
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Chapter
9. Low Birth Weight Infants.
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Chapter
10. Meningitis.
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Chapter
11. Myasthenia Gravis.
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Chapter
12. Neuralgia.
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Chapter
13. Parkinson's Disease.
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Chapter
12. Sleep Apnea.
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Chapter
13. Stroke.
.- Section 3: Ophthalmic Exosome Therapy Trials.
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Chapter
14. Dry Eyes.
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Chapter
15. Diabetic Retinopathy.
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Chapter
16. Macular Hole.
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Chapter
17. Retinitis Pigmentosa.
Jeffrey N. Weiss, M.D., is the former Chief of Retinal Surgery at the Joslin Diabetes Center in Boston, Faculty of Harvard Medical School, and Visiting Scientist at the Massachusetts Institute of Technology.
Dr. Weiss is the author of more than 100 publications, including 28 books, holds more than 22 U.S. and foreign patents and has been a Reviewer for multiple scholarly journals. He has served as a Visiting Professor, performed surgery, and lectured both nationally and internationally. Dr. Weiss is also the founder of two companies, Ocular Research Associates Inc., and Micron Ophthalmic, Inc., which have manufactured and sold Dr. Weiss inventions worldwide.
Dr. Weiss was the first to invent the equipment and develop the technique to safely perform retinal vessel cannulation. This surgery remains the only option for patients with severe stroke in the eye. He was also the first to report the use of hyperbaric oxygen treatment to successfully treat dry age-related macular degeneration and longer standing central retinal artery occlusions.
Dr. Weiss performed the first retinal stem cell surgery in 2010, and is the Principal Investigator of The Stem Cell Ophthalmology Treatment Studies I/II, the largest retinal and optic nerve stem cell studies in the world, and The Neurologic Stem Cell Treatment Study. The studies are Institutional Review Board (IRB) approved, registered with NIH, and listed on ClinicalTrials.gov.
