This handbook has been designed to provide a comprehensive and state-of-the art review and update of the major issues and challenges specific to fine needle aspiration (FNA) and small tissue core biopsies, which have emerged as primary modalities in establishing a definitive cancer diagnosis in the field of anatomic pathology, both in the U.S. and worldwide. Making an accurate diagnosis from a limited sample can be quite challenging yet crucial to patient care. The handbook, using the most current and evidence-based resources, will 1) emphasize a triple test (clinical, radiologic, and cytologic/histologic correlation); 2) stress the importance of cellblock preparation/small tissue core biopsy in modern cytopathology; 3) include over 100 diagnostic immunostaining panels/tables to address the utility and importance of ancillary studies; 4) incorporate relevant FISH and molecular tests into each chapter; and 5) summarize the pearls and pitfalls of FNA/small tissue biopsies at the beg
inning of each chapter. The book also includes highly practical presentations of typical case scenarios seen in an anatomic pathology laboratory. These are in the form of case presentations with step-by-step expert analysis. Sample cases include common but challenging situations, such as work-up of a tumor of unknown origin, evaluation of well-differentiated malignant tumors vs. benign/reactive lesions, identification of newly described tumor entities, and implementation of best practice in immunohistochemistry and molecular testing in a difficult case. Handbook of Practical Fine Needle Aspiration and Small Tissue Biopsies is written by recognized experts in their fields and provides a unique and valuable resource in the field of cytopathology, both for those currently in training and for those already in clinical practice at various skill levels. It represents a new, comprehensive yet concise resource on these timely and critical topics.v
Contents AcknowledgmentsPrefaceContributors1: Introduction and Application of Fine Needle Aspiration Biopsy Fan Lin, Jun Zhang, and Haiyan Liu 2: Salivary Glands and Other Head and Neck StructuresHaiyan Liu, Jun Zhang, and Fan Lin3: Thyroid and Parathyroid GlandsFan Lin, Haiyan Liu, and Jun Zhang4: Lymph NodesXiaohong (Mary) Zhang and Fan Lin5: BreastHaiyan Liu, Fan Lin, and Jun Zhang6: Lung and MediastinumHaiyan Liu, Jun Zhang, and Fan Lin7: LiverFan Lin, Jun Zhang, and Haiyan Liu8: Pancreas and Biliary TractFan Lin, Haiyan Liu, and Jun Zhang9: Kidney and Adrenal GlandsJun Zhang, Fan Lin, and Haiyan Liu10: Soft TissueJun Zhang, Fan Lin, and Haiyan LiuIndex