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E-grāmata: Handbook of Toxicology of Chemical Warfare Agents

Edited by (Professor and Head, Toxicology Department, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA)
  • Formāts: EPUB+DRM
  • Izdošanas datums: 21-Jan-2015
  • Izdevniecība: Academic Press Inc
  • Valoda: eng
  • ISBN-13: 9780128004944
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  • Formāts: EPUB+DRM
  • Izdošanas datums: 21-Jan-2015
  • Izdevniecība: Academic Press Inc
  • Valoda: eng
  • ISBN-13: 9780128004944
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Handbook of Toxicology of Chemical Warfare Agents, Second Edition covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors and biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, and countermeasures.

Expanding on the ground-breaking first edition, Handbook of Toxicology of Chemical Warfare Agentshas been completely updated, presenting the most recent advances in field. Brand new chapters include a case study of the Iran-Iraq war, an overview of chemical weapons of mass destruction, explosives, ricin, the human respiratory system, alternative testing methods, brain injuries, and more.

  • Unites world-leading experts to present cutting-edge, agent-specific information on chemical warfare agents and their adverse effects on human and animal health and the environment.
  • Covers all aspects of chemical warfare agent modes of action, detection, prevention, therapeutic treatment and countermeasures.
  • Features a full update on the first edition to reflect the most recent advances in the field as well as nine new chapters.

Recenzijas

"...a large, high-quality publication...provides a broader perspective than the few other titles in this field. This edition expands topics and updates references, driven by the ongoing threat, use, and research of chemical warfare agents around the world. Score: 92 - 4 Stars" --Doody's

Papildus informācija

Covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism
List of Contributors
xi
I INTRODUCTION, HISTORICAL PERSPECTIVE, AND EPIDEMIOLOGY
1 Introduction
3(4)
Ramesh C. Gupta
2 Historical Perspective of Chemical Warfare Agents
7(10)
Nathan H. Johnson
Joseph C. Larsen
Edward Meek
3 Global Impact of Chemical Warfare Agents Used Before and After 1945
17(10)
Jiri Bajgar
Josef Fusek
Jiri Kassa
Kamil Kuca
Daniel Jun
4 The Tokyo Subway Sarin Attack: Acute and Delayed Health Effects in Survivors
27(10)
Tetsu Okumura
Kenji Taki
Kouichiro Suzuki
Takemi Yoshida
Yukio Kuroiwa
Tetsuo Satoh
5 Early and Delayed Effects of Sulfur Mustard in Iranian Veterans After the Iraq--Iran Conflict
37(10)
Mahdi Balali-Mood
6 Epidemiology of Chemical Warfare Agents
47(8)
Linda A. McCauley
7 Chemical Weapons of Mass Destruction and Terrorism: A Threat Analysis
55(14)
Rene Pita
Arturo Anadon
II Agents That Can Be Used As Weapons Of Mass Destruction
8 Mustards and Vesicants
69(18)
Robert A. Young
Cheryl B. Bast
9 Organophosphate Nerve Agents
87(24)
Annetta Watson
Dennis Opresko
Robert A. Young
Weronique Hauschild
Joseph King
Kulbir Bakshi
10 Russian VX
111(20)
Vladimir Rembovskiy
Andrey Radilov
Elena Savelieva
Sergey Kuznetsov
Igor Mindukshev
Daria Prokofieva
Nadezhda Krivorotova
Natalia Khlebnikova
Richard O. Jenkins
Nikolay Goncharov
11 Riot Control Agents
131(20)
Corey J. Hilmas
12 Psychotomimetic Agent BZ (3-Quinuclidinyl Benzilate)
151(8)
Josef Fusek
Jiri Bajgar
Jiri Kassa
Kamil Kuca
Daniel Jun
13 Neurological Effects and Mechanisms of Blast Overpressure Injury
159(8)
Dorothy L. Dobbins
Xiaoping Pan
14 Thallium
167(4)
Larry J. Thompson
15 Arsenicals: Toxicity, Their Use as Chemical Warfare Agents, and Possible Remedial Measures
171(22)
Swaran J.S. Flora
16 Fluoroacetate
193(22)
Nikolay Goncharov
Elena Savelieva
Valeriy Zinchenko
Sergey Kuznetsov
Igor Mindukshev
Maxim Vinokurov
Pavel Avdonin
Natalia Voitenko
Anton Ukolov
Tatiana Orlova
Richard O. Jenkins
Anatoliy Kuznetsov
17 Strychnine
215(8)
Jiri Patocka
18 Superwarfarins
223(16)
Michael J. Murphy
Andres M. Lugo
19 PCBs, Dioxins and Furans: Human Exposure and Health Effects
239(10)
Bommanna G. Loganathan
Shigeki Masunaga
20 Polycyclic Aromatic Hydrocarbons: Implications for Developmental, Molecular, and Behavioral Neurotoxicity
249(18)
Claire E. Bollinger
Monique McCallister
Ryan Clark
Raina Rhoades
Mark Maguire
Russell E. Savage
Yuqin Jiao
Aramandla Ramesh
Darryl B. Hood
21 Carbon Monoxide: From Public Health Risk to Painless Killer
267(20)
Daya R. Varma
Shree Mulay
Sylvain Chemtob
22 Methyl Isocyanate: The Bhopal Gas
287(14)
Daya R. Varma
Shree Mulay
23 Cyanide Toxicity and its Treatment
301(14)
Rahul Bhattacharya
Swaran J.S. Flora
24 Chlorine
315(12)
Sylvia Milanez
25 Phosgene
327(10)
Cheryl B. Bast
Dana F. Glass-Mattie
26 Other Toxic Chemicals as Potential Chemical Warfare Agents
337(10)
Jiri Bajgar
Jiri Kassa
Josef Fusek
Kamil Kuca
Daniel Jun
27 Ricin
347(14)
Russell Dorsey
George Emmett
Harry Salem
28 Botulinum Toxin
361(26)
Jaime Anderson
Corey J. Hilmas
29 Anthrax
387(24)
Corey J. Hilmas
Jaime Anderson
30 Onchidal and Fasciculins
411(10)
Arturo Anadon
Maria Rosa Martinez-Larranaga
Luis G. Valerio Jr.
31 Cyanobacterial (Blue-Green Algae) Toxins
421(10)
Deon Van Der Merwe
32 Radiation and Health Effects
431(16)
Kausik Ray
Melissa Stick
33 Depleted Uranium
447(16)
George C-T Jiang
Michael Aschner
III Target Organ Toxicity
34 Chemical Warfare Agents and the Nervous System
463(14)
Jing Liu
Chibuzor Uchea
Linnzi Wright
Carey Pope
35 Behavioral Toxicity of Nerve Agents
477(12)
Jiri Kassa
Jiri Bajgar
Kamil Kuca
Daniel Jun
36 The Respiratory Toxicity of Chemical Warfare Agents
489(30)
Alfred M. Sciuto
Urmila P. Kodavanti
37 Cardiovascular System as a Target of Chemical Warfare Agents
519(16)
Csaba K. Zoltani
38 Ocular Toxicity of Chemical Warfare Agents
535(22)
Patrick M. McNutt
Tracey L. Hamilton
39 Dermal Toxicity of Sulfur Mustard
557(20)
Joshua P. Gray
Michael P. Shakarjian
Donald R. Gerecke
Robert P. Casillas
40 Skeletal Muscle
577(22)
Ramesh C. Gupta
Snjezana Zaja-Milatovic
Wolf D. Dettbarn
Jitendra K. Malik
41 Reproductive Toxicity and Endocrine Disruption of Potential Chemical Warfare Agents
599(16)
Timothy J. Evans
42 Liver Toxicity of Chemical Warfare Agents
615(12)
Shashi K. Ramaiah
Atrayee Banerjee
43 Renal System
627(12)
Sharon M. Gwaltney-Brant
44 The Immune System as a Target for Chemical Warfare Agents
639(18)
Kavita Gulati
Arunabha Ray
45 Alternative Animal Toxicity Testing of Chemical Warfare Agents
657(20)
Gopala Krishna
Saryu Goel
IV Special Topics
46 Genomics and Proteomics in Brain Complexity in Relation to Chemically Induced PTSD
677(14)
Beena M. Kadakkuzha
Xin-An Liu
Valerio Rizzo
47 Clinical and Cellular Aspects of Traumatic Brain Injury
691(18)
Jason Pitt
Yiuka Leung
48 Excitotoxicity, Oxidative Stress, and Neuronal Injury
709(16)
Snjezana Zaja-Milatovic
Ramesh C. Gupta
49 Blood---Brain Barrier Damage and Dysfunction by Chemical Toxicity
725(16)
Ramesh C. Gupta
Jason Pitt
Snjezana Zaja-Milatovic
50 Neuropathologic Effects of Chemical Warfare Agents
741(10)
Randall L. Woltjer
51 The Effects of Organophosphates in the Early Stages of Human Muscle Regeneration
751(10)
Tomaz Mars
Katarina Mis
Sergej Pirkmajer
Maja Katalinic
Zoran Grubic
52 Cholinesterase Inhibitors: From Molecular Mechanisms of Action to Current and Future Prospects
761(20)
Nir Waiskopf
Hermona Soreq
V Risks To Animals And Wildlife
53 Potential Agents That Can Cause Contamination of Animal Feedstuffs and Terror
781(10)
Robert W. Coppock
Margitta Dziwenka
54 Chemical Warfare Agents and Risks to Animal Health
791(18)
Tina Wismer
55 Threats to Wildlife by Chemical and Warfare Agents
809(8)
Robert W. Coppock
Margitta Dziwenka
VI Toxicokinetics, Toxicodynamics And Physiologically-Based Pharmacokinetics
56 Toxicokinetic Aspects of Nerve Agents and Vesicants
817(40)
Harald John
Frank Balszuweit
Kai Kehe
Franz Worek
Horst Thiermann
57 Toxicokinetics and Toxicodynamics of DFP
857(18)
Miguel Sogorb
Jorge Estevez
Eugenio Vilanova
58 Physiologically Based Pharmacokinetic Modeling of Chemical Warfare Agents
875(8)
Jeffery M. Gearhart
Peter J. Robinson
Edward M. Jakubowski
59 Biotransformation of Warfare Nerve Agents
883(14)
Milan Jokanovic
VII Analytical Methods, Biosensors And Biomarkers
60 On-Site Detection of Chemical Warfare Agents
897(18)
Yasuo Seto
61 Laboratory Analysis of Chemical Warfare Agents, Adducts, and Metabolites in Biomedical Samples
915(10)
M.J. Van Der Schans
62 Biosensors for the Detection of OP Nerve Agents
925(10)
Jun-Ichi Anzai
63 Neuropathy Target Esterase as a Biomarker and Biosensor of Delayed Neuropathic Agents
935(18)
Rudy J. Richardson
R. Mark Worden
Sanjeeva J. Wijeyesakere
Nichole D. Hein
John K. Fink
Halina F. Makhaeva
64 Biomarkers of Exposure to Organophosphorus Poisons: A New Motif for Covalent Binding to Tyrosine in Proteins That Have No Active Site Serine
953(14)
Oksana Lockridge
Lawrence M. Schopfer
Patrick Masson
65 Monitoring of Blood Cholinesterase Activity in Workers Exposed to Nerve Agents
967(12)
Daniel Jun
Jiri Bajgar
Kamil Kuca
Jiri Kassa
VIII Prophylactic, Therapeutic And Countermeasures
66 Pharmacological Prophylaxis Against Nerve Agent Poisoning: Experimental Studies and Practical Implications
979(10)
Jiri Bajgar
Josef Fusek
Jiri Kassa
Kamil Kuca
Daniel Jun
67 Prophylactic and Therapeutic Measures in Nerve Agents Poisoning
989(14)
Trond Myhrer
Aas Pal
68 Medical Management of Chemical Toxicity in Pediatrics
1003(32)
Elora Hilmas
Corey J. Hilmas
69 Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling of Countermeasures to Nerve Agents
1035(14)
Elaine Merrill
Chris Ruark
Jeffery Gearhart
Peter J. Robinson
70 Strategies to Enhance Medical Countermeasures After the Use of Chemical Warfare Agents on Civilians
1049(8)
David A. Jett
David T. Yeung
71 Pyridinium Oximes in the Treatment of Poisoning with Organophosphorus Compounds
1057(14)
Milan Jokanovic
72 Novel Cholinesterase Reactivators
1071(18)
Kamil Musilek
Jan Korabecny
Daniel Jun
Jiri Kassa
Kamil Kuca
73 Paraoxonase (PON1) and Detoxication of Nerve Agents
1089(10)
Lucio G. Costa
Toby B. Cole
Clement E. Furlong
74 The Role of Carboxylesterases in Therapeutic Intervention of Nerve Gases Poisoning
1099(8)
Sigrun Hanne Sterri
Frode Fonnum
75 Catalytic Bioscavengers: The New Generation of Bioscavenger-Based Medical Countermeasures
1107(20)
Patrick Masson
IX Decontamination And Detoxification
76 Rapid Decontamination of Chemical Warfare Agents from the Skin
1127(14)
Edward D. Clarkson
Richard K. Gordon
Index 1141
Dr. Ramesh C. Gupta, Professor & Head of Toxicology Department at Murray State university, is engaged in experimental brain research in relation to Alzheimers disease (AD) and pesticide toxicity. He has delivered lectures in Australia, Italy, Japan, Germany, France, Switzerland, Spain, Czech Republic, China, South Korea, and Sweden. He served the panels of NIH, CDC, NIOSH, and NAS. He has >350 publications to his credit, including seven major books with Elsevier: (1) Toxicology of Organophosphate and Carbamate Compounds, (2) Veterinary Toxicology: Basic and Clinical Principles, (3) Handbook of Toxicology of Chemical Warfare Agents, (4) Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology, (5) Reproductive and Developmental Toxicology, (6) Biomarkers in Toxicology and (7) Neutraceuticals. He is recipient of Murray State University's distinguished researcher award of the year-2006. He is a diplomate of American Board of Toxicology, and fellow of American College of Toxicology, American College of Nutrition, and Academy of Toxicological Sciences.