White matter transmits the electrical signals of neurons in the central nervous system; its role in health and disease is a major focus of neuroscience. Recent studies of white matter are collected here, for those working in both basic and clinical science. Early chapters review what is known about white matter in the evolution of the nervous system and brain development. Later chapters describe research on white matter changes in HIV infection, cognitive decline, dementia, drug abuse, and neuromuscular disorders, and examine the role of white matter hyper-intensities in psychiatric disorders and their association with suicide risk. There is also discussion of the latest research techniques, such as brain tissue segmentation based on multi-channel diffusion tensor imaging data, three-dimensional microstructural analysis of human brain tissue using synchrotron radiation microtomographs, and diffusion tensor MRI data acquisition methods for white matter and clinical applications. The art program features b&w and color images, illustrations, and screenshots. Information on the editors is not given. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)
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